IL153864A0 - Cyclic polyamine compounds and methods for the preparation thereof - Google Patents
Cyclic polyamine compounds and methods for the preparation thereofInfo
- Publication number
- IL153864A0 IL153864A0 IL15386401A IL15386401A IL153864A0 IL 153864 A0 IL153864 A0 IL 153864A0 IL 15386401 A IL15386401 A IL 15386401A IL 15386401 A IL15386401 A IL 15386401A IL 153864 A0 IL153864 A0 IL 153864A0
- Authority
- IL
- Israel
- Prior art keywords
- preparation
- methods
- polyamine compounds
- cyclic polyamine
- cyclic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D255/00—Heterocyclic compounds containing rings having three nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D249/00 - C07D253/00
- C07D255/02—Heterocyclic compounds containing rings having three nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D249/00 - C07D253/00 not condensed with other rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22252200P | 2000-08-02 | 2000-08-02 | |
| PCT/US2001/024282 WO2002010142A1 (fr) | 2000-08-02 | 2001-08-02 | Composes de polyamine cyclique pour la cancerotherapie |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL153864A0 true IL153864A0 (en) | 2003-07-31 |
Family
ID=22832553
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL15386401A IL153864A0 (en) | 2000-08-02 | 2001-08-02 | Cyclic polyamine compounds and methods for the preparation thereof |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP1305299A1 (fr) |
| JP (1) | JP2004505112A (fr) |
| AU (2) | AU7814301A (fr) |
| CA (1) | CA2417064A1 (fr) |
| IL (1) | IL153864A0 (fr) |
| MX (1) | MXPA03000905A (fr) |
| WO (1) | WO2002010142A1 (fr) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE335719T1 (de) | 1999-04-30 | 2006-09-15 | Cellgate Inc | Polyamine und ihre therapeutische verwendung |
| WO2002091989A2 (fr) | 2000-11-08 | 2002-11-21 | Slil Biomedical Corporation | Therapies antivirales a base de conjugues d'acides amines a une polyamine ou a des analogues de polyamine |
| AU2003279756A1 (en) * | 2002-06-26 | 2004-01-19 | Cellgate, Inc. | Porphyrin-polyamine conjugates for cancer therapy |
| EP1940773B1 (fr) | 2005-08-10 | 2015-03-18 | Johns Hopkins University | Polyamines utiles en tant q'agents therapeutiques antiparasites et anticancereux et en tant qu'inhibiteurs de demethylase specifiques a la lysine |
| US9241898B2 (en) | 2008-03-11 | 2016-01-26 | Yale University | Compositions and methods for controlled delivery of inhibitory ribonucleic acids |
| US9822364B2 (en) | 2008-03-11 | 2017-11-21 | Yale University | Compositions and methods for controlled delivery of inhibitory ribonucleic acids |
| US10465042B2 (en) | 2011-12-02 | 2019-11-05 | Yale University | Poly(amine-co-ester) nanoparticles and methods of use thereof |
| WO2013082529A1 (fr) | 2011-12-02 | 2013-06-06 | Yale University | Synthèse enzymatique de poly(amine-co-esters) et ses méthodes d'utilisation pour une libération de gènes |
| US9895451B2 (en) | 2011-12-02 | 2018-02-20 | Yale University | Formulations for targeted release of agents to low pH tissue environments or cellular compartments and methods of use thereof |
| ES2899730T3 (es) | 2012-03-07 | 2022-03-14 | Mclean Hospital Corp | Derivados de la aminoquinolina y sus usos |
| WO2013173203A1 (fr) * | 2012-05-15 | 2013-11-21 | Thermo Electron Scientific Instruments Llc | Revêtement de séparateur de faisceau diélectrique multicouche à ultra large bande |
| US11918695B2 (en) | 2014-05-09 | 2024-03-05 | Yale University | Topical formulation of hyperbranched polymer-coated particles |
| EP3721875B1 (fr) | 2014-05-09 | 2023-11-08 | Yale University | Particules revêtues de polyglycérol hyperramifié et leurs procédés de fabrication |
| CN106852146B (zh) | 2014-05-21 | 2021-08-13 | 恩特拉达治疗学股份有限公司 | 细胞穿透肽及其制备和使用方法 |
| US10815276B2 (en) | 2014-05-21 | 2020-10-27 | Entrada Therapeutics, Inc. | Cell penetrating peptides and methods of making and using thereof |
| WO2016033368A1 (fr) | 2014-08-27 | 2016-03-03 | Ohio State Innovation Foundation | Inhibiteurs améliorés de la peptidyl-calcineurine |
| US10682422B2 (en) | 2014-11-18 | 2020-06-16 | Yale University | Formulations for targeted release of agents under low pH conditions and methods of use thereof |
| WO2016081621A1 (fr) | 2014-11-18 | 2016-05-26 | Yale University | Formulations à libération ciblée d'agents sous des conditions de ph bas, et procédés d'utilisation de celles-ci |
| CA3014795A1 (fr) | 2016-02-16 | 2017-08-24 | Yale University | Compositions et procedes pour le traitement de la mucoviscidose |
| CA3014792A1 (fr) | 2016-02-16 | 2017-08-24 | Carnegie Mellon University | Compositions permettant d'ameliorer l'edition ciblee de genes et leurs procedes d'utilisation |
| WO2017197128A1 (fr) | 2016-05-11 | 2017-11-16 | Yale University | Nanoparticules de poly(amine-co-ester) et leurs procédés d'utilisation |
| WO2018187493A1 (fr) | 2017-04-04 | 2018-10-11 | Yale University | Compositions et procédés d'administration in utero |
| EP3749365A4 (fr) | 2018-01-29 | 2022-01-12 | Ohio State Innovation Foundation | Inhibiteurs peptidyliques de l'interaction calcineurine-nfat |
| TW201945014A (zh) | 2018-02-22 | 2019-12-01 | 美商安卓達治療股份有限公司 | 用於治療粒線體性神經胃腸腦病變之組合物及方法 |
| WO2019217682A1 (fr) | 2018-05-09 | 2019-11-14 | Ohio State Innovation Foundation | Peptides cycliques de pénétration cellulaire avec un ou plusieurs résidus hydrophobes |
| WO2020033951A1 (fr) | 2018-08-10 | 2020-02-13 | Yale University | Compositions et procédés d'édition de gène embryonnaire in vitro |
| US11814464B2 (en) | 2019-04-29 | 2023-11-14 | Yale University | Poly(amine-co-ester) polymers and polyplexes with modified end groups and methods of use thereof |
| WO2020257776A1 (fr) | 2019-06-21 | 2020-12-24 | Yale University | Compositions d'acides nucléiques peptidiques ayant des segments de liaison de type hoogsteen modifiés et leurs procédés d'utilisation |
| WO2020257779A1 (fr) | 2019-06-21 | 2020-12-24 | Yale University | Compositions pna à gamma-hydroxyméthyle modifiée et leurs procédés d'utilisation |
| US20220280656A1 (en) | 2019-07-31 | 2022-09-08 | Yale University | Compositions and methods for treating sickle cell disease |
| CA3183351A1 (fr) | 2020-06-19 | 2021-12-23 | Yale University | Polymeres de poly(amine-co-ester) presentant des groupes terminaux modifies et administration pulmonaire amelioree |
| US20220031633A1 (en) | 2020-07-28 | 2022-02-03 | Yale University | Poly(amine-co-ester) polymeric particles for selective pulmonary delivery |
| JP2025502630A (ja) | 2021-12-08 | 2025-01-28 | イエール・ユニバーシテイ | ナノ粒子免疫原性組成物及びワクチン接種法 |
| WO2023159189A1 (fr) | 2022-02-18 | 2023-08-24 | Yale University | Polymères de poly(amine-co-ester) ramifiés pour une expression nucléique plus efficace |
| GB202307563D0 (en) | 2023-05-19 | 2023-07-05 | Univ King Abdullah Sci & Tech | Methods and compositions |
| WO2025024693A1 (fr) | 2023-07-25 | 2025-01-30 | Massachusetts Institute Of Technology | Compositions et procédés de traitement de troubles d'expansion de répétition trinucléotidique associés à fan1 |
| CN117088825A (zh) * | 2023-10-12 | 2023-11-21 | 成都威斯津生物医药科技有限公司 | 一种可离子化脂质、含该可离子化脂质的药物组合物及其用途 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4999349A (en) * | 1990-03-22 | 1991-03-12 | Bristol-Myers Squibb Co. | BU-4164E - A and B, prolyl endopeptidase inhibitors |
| DE69704731D1 (de) * | 1996-02-27 | 2001-06-13 | Lilly Co Eli | Cryptophycinderivate und ihre Verwendung als antimikrotubuli Mittel |
-
2001
- 2001-08-02 EP EP01956110A patent/EP1305299A1/fr not_active Withdrawn
- 2001-08-02 MX MXPA03000905A patent/MXPA03000905A/es not_active Application Discontinuation
- 2001-08-02 WO PCT/US2001/024282 patent/WO2002010142A1/fr active IP Right Grant
- 2001-08-02 CA CA002417064A patent/CA2417064A1/fr not_active Abandoned
- 2001-08-02 AU AU7814301A patent/AU7814301A/xx active Pending
- 2001-08-02 JP JP2002516274A patent/JP2004505112A/ja not_active Withdrawn
- 2001-08-02 IL IL15386401A patent/IL153864A0/xx unknown
- 2001-08-02 AU AU2001278143A patent/AU2001278143B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| JP2004505112A (ja) | 2004-02-19 |
| EP1305299A1 (fr) | 2003-05-02 |
| MXPA03000905A (es) | 2003-06-24 |
| WO2002010142A1 (fr) | 2002-02-07 |
| AU2001278143B2 (en) | 2007-08-09 |
| CA2417064A1 (fr) | 2002-02-07 |
| AU7814301A (en) | 2002-02-13 |
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