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MXPA03000905A - Compuestos de poliamina ciclicos como tratamiento contra el cancer. - Google Patents

Compuestos de poliamina ciclicos como tratamiento contra el cancer.

Info

Publication number
MXPA03000905A
MXPA03000905A MXPA03000905A MXPA03000905A MXPA03000905A MX PA03000905 A MXPA03000905 A MX PA03000905A MX PA03000905 A MXPA03000905 A MX PA03000905A MX PA03000905 A MXPA03000905 A MX PA03000905A MX PA03000905 A MXPA03000905 A MX PA03000905A
Authority
MX
Mexico
Prior art keywords
cancer therapy
polyamine compounds
cyclic polyamine
cyclic
compounds
Prior art date
Application number
MXPA03000905A
Other languages
English (en)
Inventor
Benjamin Frydman
Original Assignee
Slil Biomedical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Slil Biomedical Corp filed Critical Slil Biomedical Corp
Publication of MXPA03000905A publication Critical patent/MXPA03000905A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D255/00Heterocyclic compounds containing rings having three nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D249/00 - C07D253/00
    • C07D255/02Heterocyclic compounds containing rings having three nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D249/00 - C07D253/00 not condensed with other rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D257/00Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
MXPA03000905A 2000-08-02 2001-08-02 Compuestos de poliamina ciclicos como tratamiento contra el cancer. MXPA03000905A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US22252200P 2000-08-02 2000-08-02
PCT/US2001/024282 WO2002010142A1 (en) 2000-08-02 2001-08-02 Cyclic polyamine compounds for cancer therapy

Publications (1)

Publication Number Publication Date
MXPA03000905A true MXPA03000905A (es) 2003-06-24

Family

ID=22832553

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA03000905A MXPA03000905A (es) 2000-08-02 2001-08-02 Compuestos de poliamina ciclicos como tratamiento contra el cancer.

Country Status (7)

Country Link
EP (1) EP1305299A1 (es)
JP (1) JP2004505112A (es)
AU (2) AU7814301A (es)
CA (1) CA2417064A1 (es)
IL (1) IL153864A0 (es)
MX (1) MXPA03000905A (es)
WO (1) WO2002010142A1 (es)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1177197B1 (en) 1999-04-30 2006-08-09 Cellgate, Inc. Polyamines and their use in therapy
US7312244B2 (en) 1999-04-30 2007-12-25 Cellgate, Inc. Polyamine analog-amino acid conjugates useful as anticancer agents
CA2490298A1 (en) * 2002-06-26 2004-01-08 Cellgate, Inc. Porphyrin-polyamine conjugates for cancer therapy
CN101410367A (zh) 2005-08-10 2009-04-15 约翰·霍普金斯大学 多胺用在抗寄生虫与抗癌治疗学以及作为赖氨酸-特异性脱甲基酶抑制剂
US9822364B2 (en) 2008-03-11 2017-11-21 Yale University Compositions and methods for controlled delivery of inhibitory ribonucleic acids
WO2009114614A2 (en) 2008-03-11 2009-09-17 Yale University Compositions and methods for controlled delivery of inhibitory ribonucleic acids
US9895451B2 (en) 2011-12-02 2018-02-20 Yale University Formulations for targeted release of agents to low pH tissue environments or cellular compartments and methods of use thereof
WO2013082529A1 (en) 2011-12-02 2013-06-06 Yale University Enzymatic synthesis of poly(amine-co-esters) and methods of use thereof for gene delivery
US10465042B2 (en) 2011-12-02 2019-11-05 Yale University Poly(amine-co-ester) nanoparticles and methods of use thereof
IN2012DE00661A (es) 2012-03-07 2015-08-21 Univ Delhi
WO2013173203A1 (en) * 2012-05-15 2013-11-21 Thermo Electron Scientific Instruments Llc Ultra broadband multilayer dielectric beamsplitter coating
PL3140269T3 (pl) 2014-05-09 2024-03-11 Yale University Cząstki pokryte hiperrozgałęzionym poliglicerolem oraz sposoby ich wytwarzania i zastosowania
US11918695B2 (en) 2014-05-09 2024-03-05 Yale University Topical formulation of hyperbranched polymer-coated particles
CN106852146B (zh) 2014-05-21 2021-08-13 恩特拉达治疗学股份有限公司 细胞穿透肽及其制备和使用方法
US10815276B2 (en) 2014-05-21 2020-10-27 Entrada Therapeutics, Inc. Cell penetrating peptides and methods of making and using thereof
EP3185880B1 (en) 2014-08-27 2020-02-12 Ohio State Innovation Foundation Improved peptidyl calcineurin inhibitors
US10682422B2 (en) 2014-11-18 2020-06-16 Yale University Formulations for targeted release of agents under low pH conditions and methods of use thereof
WO2016081621A1 (en) 2014-11-18 2016-05-26 Yale University Formulations for targeted release of agents under low ph conditions and methods of use thereof
CA3014792A1 (en) 2016-02-16 2017-08-24 Carnegie Mellon University Compositions for enhancing targeted gene editing and methods of use thereof
AU2017221424A1 (en) 2016-02-16 2018-09-20 Yale University Compositions and methods for treatment of cystic fibrosis
WO2017197128A1 (en) 2016-05-11 2017-11-16 Yale University Poly(amine-co-ester) nanoparticles and methods of use thereof
WO2018187493A1 (en) 2017-04-04 2018-10-11 Yale University Compositions and methods for in utero delivery
CA3078504A1 (en) 2017-10-04 2019-04-11 Ohio State Innovation Foundation Bicyclic peptidyl inhibitors
WO2019148194A2 (en) 2018-01-29 2019-08-01 Ohio State Innovation Foundation Peptidyl inhibitors of calcineurin-nfat interaction
WO2019165183A1 (en) 2018-02-22 2019-08-29 Entrada Therapeutics, Inc. Compositions and methods for treating mitochondrial neurogastrointestinal encephalopathy
US11987647B2 (en) 2018-05-09 2024-05-21 Ohio State Innovation Foundation Cyclic cell-penetrating peptides with one or more hydrophobic residues
US20210189431A1 (en) 2018-08-10 2021-06-24 Yale University Compositions and methods for embryonic gene editing in vitro
US11814464B2 (en) 2019-04-29 2023-11-14 Yale University Poly(amine-co-ester) polymers and polyplexes with modified end groups and methods of use thereof
US20220372474A1 (en) 2019-06-21 2022-11-24 Yale University Hydroxymethyl-modified gamma-pna compositions and methods of use thereof
US20220243211A1 (en) 2019-06-21 2022-08-04 Yale University Peptide nucleic acid compositions with modified hoogsteen binding segments and methods of use thereof
US20220280656A1 (en) 2019-07-31 2022-09-08 Yale University Compositions and methods for treating sickle cell disease
MX2022016581A (es) 2020-06-19 2023-02-01 Univ Yale Polimeros de poli(amina-co-ester) con grupos de extremo modificado y liberacion pulmonar mejorada.
US20220031633A1 (en) 2020-07-28 2022-02-03 Yale University Poly(amine-co-ester) polymeric particles for selective pulmonary delivery
EP4444359A2 (en) 2021-12-08 2024-10-16 Yale University Nanoparticle immunogenic compositions and vaccination methods
WO2023159189A1 (en) 2022-02-18 2023-08-24 Yale University Branched poly(amine-co-ester) polymers for more efficient nucleic expression
GB202307563D0 (en) 2023-05-19 2023-07-05 Univ King Abdullah Sci & Tech Methods and compositions
US20250032644A1 (en) 2023-07-25 2025-01-30 Massachusetts Institute Of Technology Compositions and methods for treating fan1 associated trinucleotide repeat expansion disorders
CN117088825A (zh) * 2023-10-12 2023-11-21 成都威斯津生物医药科技有限公司 一种可离子化脂质、含该可离子化脂质的药物组合物及其用途

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4999349A (en) * 1990-03-22 1991-03-12 Bristol-Myers Squibb Co. BU-4164E - A and B, prolyl endopeptidase inhibitors
DE69704731D1 (de) * 1996-02-27 2001-06-13 Lilly Co Eli Cryptophycinderivate und ihre Verwendung als antimikrotubuli Mittel

Also Published As

Publication number Publication date
EP1305299A1 (en) 2003-05-02
WO2002010142A1 (en) 2002-02-07
AU2001278143B2 (en) 2007-08-09
AU7814301A (en) 2002-02-13
CA2417064A1 (en) 2002-02-07
IL153864A0 (en) 2003-07-31
JP2004505112A (ja) 2004-02-19

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Legal Events

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