IL137954A0 - Novel substituted pyridino arylpiperazines useful in the treatment of benign prostatic hyperplasia - Google Patents

Novel substituted pyridino arylpiperazines useful in the treatment of benign prostatic hyperplasia

Info

Publication number: IL137954A0
Authority: IL; Israel
Prior art keywords: treatment; benign prostatic; prostatic hyperplasia; novel substituted; substituted pyridino
Prior art date: 1998-02-20

Application number

IL13795499A

Other languages

English (en)

Original Assignee

Ortho Mcneil Pharm Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-02-20

Filing date

1999-02-19

Publication date

2001-10-31

1999-02-19 Application filed by Ortho Mcneil Pharm Inc filed Critical Ortho Mcneil Pharm Inc

2001-10-31 Publication of IL137954A0 publication Critical patent/IL137954A0/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Urology & Nephrology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyridine Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

IL13795499A 1998-02-20 1999-02-19 Novel substituted pyridino arylpiperazines useful in the treatment of benign prostatic hyperplasia IL137954A0 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US7532198P	1998-02-20	1998-02-20
PCT/US1999/003608 WO1999042448A1 (en)	1998-02-20	1999-02-19	Novel substituted pyridino arylpiperazines useful in the treatment of benign prostatic hyperplasia

Publications (1)

Publication Number	Publication Date
IL137954A0 true IL137954A0 (en)	2001-10-31

Family

ID=22124955

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
IL13795499A IL137954A0 (en)	1998-02-20	1999-02-19	Novel substituted pyridino arylpiperazines useful in the treatment of benign prostatic hyperplasia
IL137954A IL137954A (en)	1998-02-20	2000-08-18	Converted pyridino-aripiprazines that are effective in treating the rest of the non-cancerous cell culture in the prostate

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
IL137954A IL137954A (en)	1998-02-20	2000-08-18	Converted pyridino-aripiprazines that are effective in treating the rest of the non-cancerous cell culture in the prostate

Country Status (24)

Country	Link
US (1)	US6218396B1 (pt)
EP (1)	EP1054868B1 (pt)
JP (1)	JP2002503724A (pt)
KR (1)	KR100591028B1 (pt)
CN (1)	CN1121390C (pt)
AR (1)	AR014626A1 (pt)
AT (1)	ATE250580T1 (pt)
AU (1)	AU766398B2 (pt)
BR (1)	BR9909647A (pt)
CZ (1)	CZ294136B6 (pt)
DE (1)	DE69911582T2 (pt)
DK (1)	DK1054868T3 (pt)
ES (1)	ES2209468T3 (pt)
HK (1)	HK1030776A1 (pt)
HU (1)	HUP0100781A3 (pt)
IL (2)	IL137954A0 (pt)
NO (1)	NO317103B1 (pt)
NZ (1)	NZ506462A (pt)
PL (1)	PL342339A1 (pt)
PT (1)	PT1054868E (pt)
TR (1)	TR200003220T2 (pt)
TW (1)	TW565555B (pt)
WO (1)	WO1999042448A1 (pt)
ZA (1)	ZA991315B (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2206928T3 (es) *	1997-05-12	2004-05-16	Ortho-Mcneil Pharmaceutical, Inc.	Piperacinas sustituidas con arilo utiles en el tratamiento de la hiperplasia benigna de prostata.
HUP0302893A3 (en)	2000-08-08	2006-04-28	Ortho Mcneil Pharm Inc	Non-imidazole aryloxypiperidines and pharmaceutical compositions containing them and their use
AU2002367425B2 (en)	2001-12-28	2006-03-09	Takeda Pharmaceutical Company Limited	Preventives/remedies for urinary disturbance
US8470859B2 (en)	2006-10-23	2013-06-25	Takeda Pharmaceutical Company Limited	Iminopyridine derivative and use thereof
UY31781A (es) *	2008-04-23	2009-12-14	Takeda Pharmaceutical	Derivados de iminopiridina y su uso
US8481569B2 (en)	2008-04-23	2013-07-09	Takeda Pharmaceutical Company Limited	Iminopyridine derivatives and use thereof
US20110039892A1 (en) *	2008-04-23	2011-02-17	Takeda Pharmaceutical Company Limited	Iminopyridine derivative and use thereof
CN103980195A (zh) *	2014-04-28	2014-08-13	广州医科大学	酰胺类苯基哌嗪衍生物及其盐与在制备治疗良性前列腺增生症药物中的应用
CN108530391B (zh) *	2018-05-17	2022-05-17	袁牧	一种酰胺类芳基哌嗪衍生物及其制备方法与应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2027898A6 (es) *	1991-01-24	1992-06-16	Espanola Prod Quimicos	Procedimiento de preparacion de nuevos derivados de la 2-metoxifenilpiperacina.
US5403847A (en)	1992-11-13	1995-04-04	Synaptic Pharmaceutical Corporation	Use of α1C specific compounds to treat benign prostatic hyperlasia
IT1266582B1 (it) *	1993-07-30	1997-01-09	Recordati Chem Pharm	Derivati (di)azacicloesanici e diazacicloeptanici
DE4425146A1 (de) *	1994-07-15	1996-01-18	Basf Ag	Verwendung heterocyclischer Verbindungen
US5688795A (en) *	1994-11-08	1997-11-18	Syntex (U.S.A.) Inc.	3-(4-phenylpiperazin-1-yl)propyl-amino, thio and oxy!-pyridine, pyrimidine and benzene derivatives as α1 -adrenoceptor antagonists
WO1999003833A1 (en) *	1997-07-15	1999-01-28	Sankyo Company, Limited	Piperazine derivatives

1999
- 1999-02-18 US US09/252,313 patent/US6218396B1/en not_active Expired - Lifetime
- 1999-02-18 ZA ZA9901315A patent/ZA991315B/xx unknown
- 1999-02-19 PL PL99342339A patent/PL342339A1/xx unknown
- 1999-02-19 CZ CZ20003044A patent/CZ294136B6/cs not_active IP Right Cessation
- 1999-02-19 DK DK99934281T patent/DK1054868T3/da active
- 1999-02-19 KR KR1020007009156A patent/KR100591028B1/ko not_active IP Right Cessation
- 1999-02-19 WO PCT/US1999/003608 patent/WO1999042448A1/en active IP Right Grant
- 1999-02-19 PT PT99934281T patent/PT1054868E/pt unknown
- 1999-02-19 AU AU33025/99A patent/AU766398B2/en not_active Ceased
- 1999-02-19 HU HU0100781A patent/HUP0100781A3/hu unknown
- 1999-02-19 EP EP99934281A patent/EP1054868B1/en not_active Expired - Lifetime
- 1999-02-19 BR BR9909647-1A patent/BR9909647A/pt not_active Application Discontinuation
- 1999-02-19 TR TR2000/03220T patent/TR200003220T2/xx unknown
- 1999-02-19 ES ES99934281T patent/ES2209468T3/es not_active Expired - Lifetime
- 1999-02-19 JP JP2000532400A patent/JP2002503724A/ja active Pending
- 1999-02-19 IL IL13795499A patent/IL137954A0/xx active IP Right Grant
- 1999-02-19 DE DE69911582T patent/DE69911582T2/de not_active Expired - Fee Related
- 1999-02-19 NZ NZ506462A patent/NZ506462A/en unknown
- 1999-02-19 CN CN99803027A patent/CN1121390C/zh not_active Expired - Fee Related
- 1999-02-19 AT AT99934281T patent/ATE250580T1/de not_active IP Right Cessation
- 1999-02-23 AR ARP990100675A patent/AR014626A1/es active IP Right Grant
- 1999-04-02 TW TW088102511A patent/TW565555B/zh not_active IP Right Cessation
2000
- 2000-08-18 IL IL137954A patent/IL137954A/en not_active IP Right Cessation
- 2000-08-18 NO NO20004141A patent/NO317103B1/no not_active IP Right Cessation
2001
- 2001-03-08 HK HK01101679A patent/HK1030776A1/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
ATE250580T1 (de)	2003-10-15
ES2209468T3 (es)	2004-06-16
HK1030776A1 (en)	2001-05-18
AU3302599A (en)	1999-09-06
NO317103B1 (no)	2004-08-09
NZ506462A (en)	2003-07-25
US6218396B1 (en)	2001-04-17
EP1054868A1 (en)	2000-11-29
IL137954A (en)	2007-06-03
AR014626A1 (es)	2001-03-28
PT1054868E (pt)	2004-01-30
CN1291188A (zh)	2001-04-11
PL342339A1 (en)	2001-06-04
WO1999042448A1 (en)	1999-08-26
TW565555B (en)	2003-12-11
CN1121390C (zh)	2003-09-17
HUP0100781A2 (hu)	2001-08-28
KR100591028B1 (ko)	2006-06-22
TR200003220T2 (tr)	2001-04-20
EP1054868B1 (en)	2003-09-24
DE69911582T2 (de)	2005-09-15
DK1054868T3 (da)	2003-12-22
DE69911582D1 (de)	2003-10-30
AU766398B2 (en)	2003-10-16
BR9909647A (pt)	2000-11-21
NO20004141D0 (no)	2000-08-18
NO20004141L (no)	2000-10-19
KR20010041115A (ko)	2001-05-15
CZ20003044A3 (cs)	2001-04-11
ZA991315B (en)	2000-11-20
CZ294136B6 (cs)	2004-10-13
HUP0100781A3 (en)	2002-12-28
JP2002503724A (ja)	2002-02-05

Publication	Publication Date	Title
NO993396L (no)	1999-07-09	Kinolin- og kinolinforbindelser nyttige i terapi, spesielt i behandlingen av benign prostatisk hyperplasi
AU1316000A (en)	2000-05-15	Compositions and methods for treating benign prostatic hyperplasia using tocotrienols
IL141235A0 (en)	2011-08-01	Combined use of an alpha-adrenoceptor antagonist and amuscarinic antagonist in the treatment of benign prostatic hyperplasi
AU3011299A (en)	1999-10-18	Combination therapy for the treatment of benign prostatic hyperplasia
AU1657097A (en)	1997-10-02	Use of alpha1-adrenoreceptor antagonists in the prevention and treatment of benign prostatic hyperplasia
IL137954A0 (en)	2001-10-31	Novel substituted pyridino arylpiperazines useful in the treatment of benign prostatic hyperplasia
ZA983968B (en)	1999-11-11	Arylsubstituted piperazines useful in the treatment of benign prostatic hyperplasia.
ZA981781B (en)	1999-03-03	The use of levobupivacaine in treating migraine
EP1139981A4 (en)	2002-04-17	COMPOSITIONS AND RELATED METHODS OF USE
ZA982819B (en)	1999-10-04	Treatment or prophylaxis of prostatic cancer and benign prostatic hyperplasia with selective estrogn receptor modulators.
ZA991319B (en)	2000-11-20	Novel phthalimido arylpiperazines useful in the treatment of benign prostatic hyperplasia.
AU9128998A (en)	1999-03-22	Composition and method for the treatment of benign prostatic hyperplasia and prostatitis
GB9602903D0 (en)	1996-04-10	Conjugates useful in the treatment of benign prostatic hyperplasia
EP0748627A3 (en)	1997-05-21	Melatonin agonists for the treatment of benign forms of hyperplasia of the prostate
AU2002232403A1 (en)	2002-05-15	Del-1 and benign prostatic hyperplasia
AU2002300904A1 (en)	2003-02-20	Arylsubstituted piperazines useful in the treatment of benign prostatic hyperplasia
GB9810895D0 (en)	1998-07-22	Combination therapy for the treatment of benign prostatic hyperplasia
AU2003204320A1 (en)	2003-06-19	Heterocycles useful in the treatment of benign prostatic hyperplasia and intermediates thereof

Legal Events

Date	Code	Title
2007-10-31	FF	Patent granted
2007-12-03	KB	Patent renewed
2009-07-27	KB	Patent renewed