IL131854A0 - Novel pyridine derivatives and pharmaceutical compositions containing them - Google Patents

Novel pyridine derivatives and pharmaceutical compositions containing them

Info

Publication number: IL131854A0
Authority: IL; Israel
Prior art keywords: pharmaceutical compositions; compositions containing; pyridine derivatives; novel pyridine; novel
Prior art date: 1997-04-01

Application number

IL13185498A

Other languages

English (en)

Original Assignee

Astra Pharma Prod

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-04-01

Filing date

1998-03-27

Publication date

2001-03-19

1997-04-01 Priority claimed from SE9701194A external-priority patent/SE9701194D0/xx

1997-06-09 Priority claimed from SE9702200A external-priority patent/SE9702200D0/xx

1997-11-28 Priority claimed from SE9704402A external-priority patent/SE9704402D0/xx

1998-03-27 Application filed by Astra Pharma Prod filed Critical Astra Pharma Prod

2001-03-19 Publication of IL131854A0 publication Critical patent/IL131854A0/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/64—One oxygen atom attached in position 2 or 6
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/84—Nitriles
- C07D213/85—Nitriles in position 3
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Immunology (AREA)
Pulmonology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Pyridine Compounds (AREA)

IL13185498A 1997-04-01 1998-03-27 Novel pyridine derivatives and pharmaceutical compositions containing them IL131854A0 (en)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
SE9701194A SE9701194D0 (sv)	1997-04-01	1997-04-01	Novel compounds
SE9702200A SE9702200D0 (sv)	1997-06-09	1997-06-09	Novel compounds
SE9704402A SE9704402D0 (sv)	1997-11-28	1997-11-28	Novel compounds
PCT/SE1998/000575 WO1998043971A1 (en)	1997-04-01	1998-03-27	Novel pyridine derivatives and pharmaceutical compositions containing them

Publications (1)

Publication Number	Publication Date
IL131854A0 true IL131854A0 (en)	2001-03-19

Family

ID=27355867

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL13185498A IL131854A0 (en)	1997-04-01	1998-03-27	Novel pyridine derivatives and pharmaceutical compositions containing them

Country Status (23)

Country	Link
US (1)	US6143751A (pt)
EP (1)	EP0984961B1 (pt)
JP (1)	JP2001517228A (pt)
KR (1)	KR20010005840A (pt)
CN (1)	CN1258296A (pt)
AR (1)	AR012216A1 (pt)
AT (1)	ATE202351T1 (pt)
AU (1)	AU6861198A (pt)
BR (1)	BR9808447A (pt)
CA (1)	CA2284597A1 (pt)
DE (1)	DE69800970T2 (pt)
DK (1)	DK0984961T3 (pt)
EE (1)	EE9900435A (pt)
ES (1)	ES2159943T3 (pt)
GR (1)	GR3036638T3 (pt)
ID (1)	ID23163A (pt)
IL (1)	IL131854A0 (pt)
NO (1)	NO994764L (pt)
PL (1)	PL335884A1 (pt)
PT (1)	PT984961E (pt)
SK (1)	SK133399A3 (pt)
TR (1)	TR199902433T2 (pt)
WO (1)	WO1998043971A1 (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2000040557A1 (en) *	1999-01-08	2000-07-13	Vertex Pharmaceuticals Incorporated	Process for the formation of intermediates useful for the preparation of pharmaceuticals
CA2314458A1 (en) *	1999-08-02	2001-02-02	Kazumi Okuro	Process for production of 3-(3-pyridyl)-1-propanol derivatives
US6376524B1 (en)	2000-06-21	2002-04-23	Sunesis Pharmaceuticals, Inc.	Triphenyl compounds as interleukin-4 antagonists
JO3598B1 (ar) *	2006-10-10	2020-07-05	Infinity Discovery Inc	الاحماض والاسترات البورونية كمثبطات اميد هيدروليز الحامض الدهني
MX361692B (es)	2010-02-03	2018-12-13	Infinity Pharmaceuticals Inc	Inhibidores de amida hidrolasa de ácido graso.
WO2013097052A1 (en)	2011-12-30	2013-07-04	Abbott Laboratories	Bromodomain inhibitors
CN104718201A (zh)	2012-06-12	2015-06-17	艾伯维公司	吡啶酮和哒嗪酮衍生物
EP3693369A3 (en)	2016-04-15	2020-09-09	AbbVie Inc.	Bromodomain inhibitors

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU7955287A (en) *	1986-10-14	1988-04-21	G.D. Searle & Co.	Pyridine derivatives
EP0264114A1 (en) *	1986-10-16	1988-04-20	G.D. Searle & Co.	Alpha-[(phenylmethoxy)methyl]pyridine-alkanol derivatives
KR19990071968A (ko) *	1995-12-06	1999-09-27	니콜라스 피터 비가르트 (니크 비가르트), 콜린 레드롭	화합물

1998
- 1998-03-27 ES ES98914202T patent/ES2159943T3/es not_active Expired - Lifetime
- 1998-03-27 CN CN98805505A patent/CN1258296A/zh active Pending
- 1998-03-27 IL IL13185498A patent/IL131854A0/xx unknown
- 1998-03-27 ID IDW991125D patent/ID23163A/id unknown
- 1998-03-27 BR BR9808447-0A patent/BR9808447A/pt not_active IP Right Cessation
- 1998-03-27 DK DK98914202T patent/DK0984961T3/da active
- 1998-03-27 DE DE69800970T patent/DE69800970T2/de not_active Expired - Fee Related
- 1998-03-27 KR KR1019997008914A patent/KR20010005840A/ko not_active Application Discontinuation
- 1998-03-27 PL PL98335884A patent/PL335884A1/xx unknown
- 1998-03-27 CA CA002284597A patent/CA2284597A1/en not_active Abandoned
- 1998-03-27 SK SK1333-99A patent/SK133399A3/sk unknown
- 1998-03-27 WO PCT/SE1998/000575 patent/WO1998043971A1/en not_active Application Discontinuation
- 1998-03-27 PT PT98914202T patent/PT984961E/pt unknown
- 1998-03-27 EE EEP199900435A patent/EE9900435A/xx unknown
- 1998-03-27 EP EP98914202A patent/EP0984961B1/en not_active Expired - Lifetime
- 1998-03-27 JP JP54155998A patent/JP2001517228A/ja active Pending
- 1998-03-27 TR TR1999/02433T patent/TR199902433T2/xx unknown
- 1998-03-27 US US09/068,521 patent/US6143751A/en not_active Expired - Fee Related
- 1998-03-27 AU AU68611/98A patent/AU6861198A/en not_active Abandoned
- 1998-03-27 AT AT98914202T patent/ATE202351T1/de not_active IP Right Cessation
- 1998-03-31 AR ARP980101459A patent/AR012216A1/es unknown
1999
- 1999-09-30 NO NO994764A patent/NO994764L/no not_active Application Discontinuation
2001
- 2001-09-18 GR GR20010401496T patent/GR3036638T3/el not_active IP Right Cessation

Also Published As

Publication number	Publication date
GR3036638T3 (en)	2001-12-31
NO994764D0 (no)	1999-09-30
SK133399A3 (en)	2000-05-16
EP0984961B1 (en)	2001-06-20
WO1998043971A1 (en)	1998-10-08
PT984961E (pt)	2001-11-30
CN1258296A (zh)	2000-06-28
ID23163A (id)	2000-03-23
JP2001517228A (ja)	2001-10-02
NO994764L (no)	1999-09-30
DE69800970T2 (de)	2002-04-04
EP0984961A1 (en)	2000-03-15
US6143751A (en)	2000-11-07
CA2284597A1 (en)	1998-10-08
AU6861198A (en)	1998-10-22
DE69800970D1 (de)	2001-07-26
EE9900435A (et)	2000-04-17
KR20010005840A (ko)	2001-01-15
ES2159943T3 (es)	2001-10-16
DK0984961T3 (da)	2001-09-17
PL335884A1 (en)	2000-05-22
TR199902433T2 (xx)	2000-04-21
ATE202351T1 (de)	2001-07-15
BR9808447A (pt)	2000-05-23
AR012216A1 (es)	2000-09-27

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