IL117485A0 - Method of treating acute myocardial infarction with hirudin and acetysalicylic acid in patients not undergoing thrombolytic treatment - Google Patents

Method of treating acute myocardial infarction with hirudin and acetysalicylic acid in patients not undergoing thrombolytic treatment

Info

Publication number: IL117485A0
Authority: IL; Israel
Prior art keywords: hirudin; patients; myocardial infarction; acute myocardial; treating acute
Prior art date: 1995-03-15

Application number

IL11748596A

Other languages

English (en)

Inventor

Hubert Dr Heinrichs

Charles H Hennekens

Original Assignee

Behringwerke Ag

Brigham & Womens Hospital

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-03-15

Filing date

1996-03-14

Publication date

1996-07-23

1996-03-14 Application filed by Behringwerke Ag, Brigham & Womens Hospital filed Critical Behringwerke Ag

1996-07-23 Publication of IL117485A0 publication Critical patent/IL117485A0/xx

Links

BSYNRYMUTXBXSQ-UHFFFAOYSA-N Aspirin Chemical compound CC(=O)OC1=CC=CC=C1C(O)=O BSYNRYMUTXBXSQ-UHFFFAOYSA-N 0.000 title 1
102000007625 Hirudins Human genes 0.000 title 1
108010007267 Hirudins Proteins 0.000 title 1
206010000891 acute myocardial infarction Diseases 0.000 title 1
239000003146 anticoagulant agent Substances 0.000 title 1
WQPDUTSPKFMPDP-OUMQNGNKSA-N hirudin Chemical compound C([C@@H](C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC=1C=CC(OS(O)(=O)=O)=CC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC=1NC=NC=1)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](CCCCN)NC(=O)[C@H]1N(CCC1)C(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H]1NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@@H]2CSSC[C@@H](C(=O)N[C@@H](CCC(O)=O)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@H](C(=O)N[C@H](C(NCC(=O)N[C@@H](CCC(N)=O)C(=O)NCC(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N2)=O)CSSC1)C(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H]1NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CC=2C=CC(O)=CC=2)NC(=O)[C@@H](NC(=O)[C@@H](N)C(C)C)C(C)C)[C@@H](C)O)CSSC1)C(C)C)[C@@H](C)O)[C@@H](C)O)C1=CC=CC=C1 WQPDUTSPKFMPDP-OUMQNGNKSA-N 0.000 title 1
229940006607 hirudin Drugs 0.000 title 1
230000002537 thrombolytic effect Effects 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
- A61K31/612—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid
- A61K31/616—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid by carboxylic acids, e.g. acetylsalicylic acid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
- A61K38/57—Protease inhibitors from animals; from humans
- A61K38/58—Protease inhibitors from animals; from humans from leeches, e.g. hirudin, eglin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Epidemiology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Immunology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Gastroenterology & Hepatology (AREA)
Zoology (AREA)
Tropical Medicine & Parasitology (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Diabetes (AREA)
Hematology (AREA)
Dermatology (AREA)
Nutrition Science (AREA)
Physiology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Peptides Or Proteins (AREA)

IL11748596A 1995-03-15 1996-03-14 Method of treating acute myocardial infarction with hirudin and acetysalicylic acid in patients not undergoing thrombolytic treatment IL117485A0 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US40526995A	1995-03-15	1995-03-15
US44055695A	1995-05-12	1995-05-12

Publications (1)

Publication Number	Publication Date
IL117485A0 true IL117485A0 (en)	1996-07-23

Family

ID=27019016

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL11748596A IL117485A0 (en)	1995-03-15	1996-03-14	Method of treating acute myocardial infarction with hirudin and acetysalicylic acid in patients not undergoing thrombolytic treatment

Country Status (14)

Country	Link
EP (1)	EP0732102A3 (xx)
JP (1)	JPH0920681A (xx)
KR (1)	KR960033468A (xx)
CN (1)	CN1141809A (xx)
AR (1)	AR002968A1 (xx)
AU (1)	AU711660B2 (xx)
BR (1)	BR9601024A (xx)
CA (1)	CA2171509A1 (xx)
FI (1)	FI961171L (xx)
IL (1)	IL117485A0 (xx)
NO (1)	NO961046L (xx)
NZ (1)	NZ286082A (xx)
SG (1)	SG43242A1 (xx)
UY (1)	UY24181A1 (xx)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2004262776A (ja) *	2003-02-21	2004-09-24	Teikoku Seiyaku Co Ltd	血管新生促進剤
WO2005027896A1 (ja) *	2003-09-19	2005-03-31	Kissei Pharmaceutical Co., Ltd.	併用医薬
US20060222640A1 (en) *	2005-03-29	2006-10-05	Boehringer Ingelheim International Gmbh	New pharmaceutical compositions for treatment of thrombosis
JP2009543842A (ja) *	2006-07-17	2009-12-10	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	心臓血管分野における直接トロンビン阻害薬のための新規適応

1996
- 1996-02-27 NZ NZ286082A patent/NZ286082A/en unknown
- 1996-02-29 SG SG1996006166A patent/SG43242A1/en unknown
- 1996-03-11 CA CA002171509A patent/CA2171509A1/en not_active Abandoned
- 1996-03-12 AR ARP960101719A patent/AR002968A1/es unknown
- 1996-03-12 EP EP96103821A patent/EP0732102A3/en not_active Withdrawn
- 1996-03-13 AU AU48072/96A patent/AU711660B2/en not_active Ceased
- 1996-03-13 FI FI961171A patent/FI961171L/fi unknown
- 1996-03-14 NO NO961046A patent/NO961046L/no not_active Application Discontinuation
- 1996-03-14 CN CN96101995A patent/CN1141809A/zh active Pending
- 1996-03-14 JP JP8057083A patent/JPH0920681A/ja active Pending
- 1996-03-14 KR KR1019960006762A patent/KR960033468A/ko not_active Application Discontinuation
- 1996-03-14 IL IL11748596A patent/IL117485A0/xx unknown
- 1996-03-15 BR BR9601024A patent/BR9601024A/pt active Search and Examination
- 1996-03-15 UY UY24181A patent/UY24181A1/es unknown

Also Published As

Publication number	Publication date
NO961046L (no)	1996-09-16
EP0732102A2 (en)	1996-09-18
FI961171A0 (fi)	1996-03-13
AR002968A1 (es)	1998-05-27
CA2171509A1 (en)	1996-09-16
AU711660B2 (en)	1999-10-21
AU4807296A (en)	1996-09-26
UY24181A1 (es)	1996-03-20
NZ286082A (en)	1998-09-24
BR9601024A (pt)	1997-12-30
KR960033468A (ko)	1996-10-22
EP0732102A3 (en)	1999-01-27
CN1141809A (zh)	1997-02-05
SG43242A1 (en)	1997-10-17
JPH0920681A (ja)	1997-01-21
FI961171L (fi)	1996-09-16
NO961046D0 (no)	1996-03-14

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