IL103262A - Crystalline etoposide 4'-phosphate diethanolate, its preparation and pharmaceutical compositon containing it - Google Patents

Crystalline etoposide 4'-phosphate diethanolate, its preparation and pharmaceutical compositon containing it

Info

Publication number: IL103262A
Authority: IL; Israel
Prior art keywords: preparation; pharmaceutical compositon; phosphate diethanolate; crystalline etoposide; compositon containing
Prior art date: 1991-10-08

Application number

IL103262A

Other languages

English (en)

Other versions

IL103262A0 (en

Original Assignee

Bristol Myers Squibb Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-10-08

Filing date

1992-09-23

Publication date

1997-06-10

1992-09-23 Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co

1993-02-21 Publication of IL103262A0 publication Critical patent/IL103262A0/xx

1997-06-10 Publication of IL103262A publication Critical patent/IL103262A/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Medicinal Preparation (AREA)

IL103262A 1991-10-08 1992-09-23 Crystalline etoposide 4'-phosphate diethanolate, its preparation and pharmaceutical compositon containing it IL103262A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/773,056 US5648474A (en)	1991-10-08	1991-10-08	Crystalline etoposide 4'-phosphate diethanolate

Publications (2)

Publication Number	Publication Date
IL103262A0 IL103262A0 (en)	1993-02-21
IL103262A true IL103262A (en)	1997-06-10

Family

ID=25097069

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL103262A IL103262A (en)	1991-10-08	1992-09-23	Crystalline etoposide 4'-phosphate diethanolate, its preparation and pharmaceutical compositon containing it

Country Status (27)

Country	Link
US (1)	US5648474A (zh)
EP (1)	EP0537555B1 (zh)
JP (1)	JP3205816B2 (zh)
KR (1)	KR100243981B1 (zh)
CN (1)	CN1030610C (zh)
AT (1)	ATE156832T1 (zh)
AU (1)	AU650572B2 (zh)
CA (1)	CA2079581C (zh)
CZ (1)	CZ283735B6 (zh)
DE (1)	DE69221573T2 (zh)
DK (1)	DK0537555T3 (zh)
EG (1)	EG20187A (zh)
ES (1)	ES2109970T3 (zh)
FI (1)	FI105034B (zh)
GR (1)	GR3025176T3 (zh)
HU (2)	HU213606B (zh)
IL (1)	IL103262A (zh)
MX (1)	MX9205777A (zh)
MY (1)	MY108969A (zh)
NO (1)	NO178342C (zh)
NZ (1)	NZ244521A (zh)
PH (1)	PH31666A (zh)
PL (1)	PL168332B1 (zh)
RU (1)	RU2042686C1 (zh)
SK (1)	SK278935B6 (zh)
TW (1)	TW239863B (zh)
ZA (1)	ZA926903B (zh)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5459248A (en) *	1993-11-04	1995-10-17	Bristol-Myers Squibb Company	Process of preparing etoposide phosphate and etoposide

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4914222A (en) *	1983-08-29	1990-04-03	Merck & Co., Inc.	Crystalline salts of L or (S)-3-(3,4-dihydroxyphenyl)-2-methylalanine esters and process
US4670578A (en) *	1983-08-29	1987-06-02	Merck & Co., Inc.	Process for crystalline salts of L or (S)-3-(3,4-dihydroxyphenyl)-2-methylalanine esters
US4713246A (en) *	1984-03-19	1987-12-15	Bristol-Myers Company	Etoposide oral dosage form
US4775751A (en) *	1985-06-03	1988-10-04	Eli Lilly & Company	Process for cephalexin hydrochloride alcoholates
US4927638A (en) *	1986-10-08	1990-05-22	Bristol-Myers Company	Etoposide solutions
US4904768A (en) *	1987-08-04	1990-02-27	Bristol-Myers Company	Epipodophyllotoxin glucoside 4'-phosphate derivatives
ES2061891T3 (es) *	1988-11-16	1994-12-16	Nippon Kayaku Kk	Cristales de dihidrato de dihidrocloruro de compuesto de etoposido-2-dimetilamina y un procedimiento para su produccion.
US5081234A (en) *	1990-04-30	1992-01-14	Bristol-Myers Squibb Co.	4'-demethylepipodophyllotoxin glycosides

1991
- 1991-10-08 US US07/773,056 patent/US5648474A/en not_active Expired - Lifetime
1992
- 1992-03-07 TW TW081101734A patent/TW239863B/zh not_active IP Right Cessation
- 1992-09-10 ZA ZA926903A patent/ZA926903B/xx unknown
- 1992-09-11 MY MYPI92001632A patent/MY108969A/en unknown
- 1992-09-22 JP JP30024092A patent/JP3205816B2/ja not_active Expired - Lifetime
- 1992-09-23 AU AU25301/92A patent/AU650572B2/en not_active Expired
- 1992-09-23 IL IL103262A patent/IL103262A/xx not_active IP Right Cessation
- 1992-09-26 EG EG56692A patent/EG20187A/xx active
- 1992-09-28 NZ NZ244521A patent/NZ244521A/en not_active IP Right Cessation
- 1992-09-28 NO NO923754A patent/NO178342C/no not_active IP Right Cessation
- 1992-09-29 PL PL92296078A patent/PL168332B1/pl unknown
- 1992-09-29 FI FI924359A patent/FI105034B/fi not_active IP Right Cessation
- 1992-09-30 CZ CS922986A patent/CZ283735B6/cs not_active IP Right Cessation
- 1992-09-30 HU HU9203119A patent/HU213606B/hu unknown
- 1992-09-30 ES ES92116749T patent/ES2109970T3/es not_active Expired - Lifetime
- 1992-09-30 SK SK2986-92A patent/SK278935B6/sk not_active IP Right Cessation
- 1992-09-30 AT AT92116749T patent/ATE156832T1/de active
- 1992-09-30 DE DE69221573T patent/DE69221573T2/de not_active Expired - Lifetime
- 1992-09-30 EP EP92116749A patent/EP0537555B1/en not_active Expired - Lifetime
- 1992-09-30 CN CN92111350A patent/CN1030610C/zh not_active Expired - Lifetime
- 1992-09-30 DK DK92116749.0T patent/DK0537555T3/da active
- 1992-09-30 PH PH45023A patent/PH31666A/en unknown
- 1992-09-30 CA CA002079581A patent/CA2079581C/en not_active Expired - Lifetime
- 1992-09-30 RU SU925052958A patent/RU2042686C1/ru active
- 1992-10-01 KR KR1019920018032A patent/KR100243981B1/ko not_active Expired - Lifetime
- 1992-10-08 MX MX9205777A patent/MX9205777A/es unknown
1995
- 1995-06-22 HU HU95P/P00385P patent/HU211672A9/hu unknown
1997
- 1997-10-29 GR GR970402811T patent/GR3025176T3/el unknown

Also Published As

Publication number	Publication date
CA2079581A1 (en)	1993-04-09
ZA926903B (en)	1993-05-03
IL103262A0 (en)	1993-02-21
HU213606B (en)	1997-08-28
PL296078A1 (en)	1993-04-19
EP0537555A1 (en)	1993-04-21
ES2109970T3 (es)	1998-02-01
DE69221573D1 (de)	1997-09-18
JP3205816B2 (ja)	2001-09-04
SK298692A3 (en)	1998-04-08
SK278935B6 (sk)	1998-04-08
NO923754D0 (no)	1992-09-28
NO178342C (no)	1996-03-06
HU9203119D0 (en)	1992-12-28
GR3025176T3 (en)	1998-02-27
PH31666A (en)	1999-01-12
NO923754L (no)	1993-04-13
PL168332B1 (pl)	1996-02-29
JPH05194575A (ja)	1993-08-03
EP0537555B1 (en)	1997-08-13
CN1030610C (zh)	1996-01-03
US5648474A (en)	1997-07-15
HUT62309A (en)	1993-04-28
TW239863B (zh)	1995-02-01
CA2079581C (en)	2002-11-12
KR930007968A (ko)	1993-05-20
CZ298692A3 (en)	1993-04-14
NO178342B (no)	1995-11-27
MX9205777A (es)	1993-04-01
DE69221573T2 (de)	1998-02-26
DK0537555T3 (da)	1998-01-26
FI924359L (fi)	1993-04-09
KR100243981B1 (ko)	2000-02-01
ATE156832T1 (de)	1997-08-15
AU2530192A (en)	1993-04-22
RU2042686C1 (ru)	1995-08-27
CN1071432A (zh)	1993-04-28
FI924359A0 (fi)	1992-09-29
CZ283735B6 (cs)	1998-06-17
NZ244521A (en)	1994-02-25
EG20187A (en)	1997-09-30
HU211672A9 (en)	1995-12-28
AU650572B2 (en)	1994-06-23
MY108969A (en)	1996-11-30
FI105034B (fi)	2000-05-31

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Legal Events

Date	Code	Title
1998-01-04	FF	Patent granted
1998-06-15	KB	Patent renewed
1999-01-26	KB	Patent renewed
2002-12-01	KB	Patent renewed
2006-10-30	KB	Patent renewed
2010-11-30	KB	Patent renewed
2013-04-30	EXP	Patent expired