ID18983A - Pirazola sebagai inhibitor sekresi fosfolipase a2 non-pankreas pada manusia - Google Patents

Pirazola sebagai inhibitor sekresi fosfolipase a2 non-pankreas pada manusia

Info

Publication number: ID18983A
Authority: ID; Indonesia
Prior art keywords: secression; pirazola; secretary; human; pancreas phospholipase
Prior art date: 1996-12-04

Application number

IDP973793A

Other languages

English (en)

Inventor

Peter Jeremy Doman

Gary Alan Hite

Edward David Mihelich

Tulio Nmn Suarez

Stuart Edmund Willetts

Original Assignee

Lilly Co Eli

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-12-04

Filing date

1997-11-27

Publication date

1998-05-28

1997-11-27 Application filed by Lilly Co Eli filed Critical Lilly Co Eli

1998-05-28 Publication of ID18983A publication Critical patent/ID18983A/id

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/44—Oxygen and nitrogen or sulfur and nitrogen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Pulmonology (AREA)
Immunology (AREA)
Cardiology (AREA)
Rheumatology (AREA)
Heart & Thoracic Surgery (AREA)
Pain & Pain Management (AREA)
Diabetes (AREA)
Hematology (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Enzymes And Modification Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Investigating Or Analysing Materials By Optical Means (AREA)

IDP973793A 1996-12-04 1997-11-27 Pirazola sebagai inhibitor sekresi fosfolipase a2 non-pankreas pada manusia ID18983A (id)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US3321696P	1996-12-04	1996-12-04

Publications (1)

Publication Number	Publication Date
ID18983A true ID18983A (id)	1998-05-28

Family

ID=21869147

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IDP973793A ID18983A (id)	1996-12-04	1997-11-27	Pirazola sebagai inhibitor sekresi fosfolipase a2 non-pankreas pada manusia

Country Status (22)

Country	Link
US (1)	US5972972A (id)
EP (1)	EP0846687B1 (id)
JP (1)	JP2002515053A (id)
KR (1)	KR20000057366A (id)
AR (1)	AR010743A1 (id)
AT (1)	ATE203985T1 (id)
AU (1)	AU5365598A (id)
BR (1)	BR9713993A (id)
CA (1)	CA2274048A1 (id)
CO (1)	CO4910169A1 (id)
DE (1)	DE69706027T2 (id)
DK (1)	DK0846687T3 (id)
ES (1)	ES2160897T3 (id)
HK (1)	HK1011865A1 (id)
HU (1)	HUP0000292A3 (id)
ID (1)	ID18983A (id)
IL (1)	IL130202A0 (id)
PE (1)	PE20599A1 (id)
PT (1)	PT846687E (id)
TW (1)	TW432051B (id)
WO (1)	WO1998024437A1 (id)
ZA (1)	ZA9710878B (id)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6979686B1 (en)	2001-12-07	2005-12-27	Pharmacia Corporation	Substituted pyrazoles as p38 kinase inhibitors
US6514977B1 (en)	1997-05-22	2003-02-04	G.D. Searle & Company	Substituted pyrazoles as p38 kinase inhibitors
AU7726898A (en)	1997-05-22	1998-12-11	G.D. Searle & Co.	Pyrazole derivatives as p38 kinase inhibitors
JP4412521B2 (ja)	1998-03-31	2010-02-10	塩野義製薬株式会社	ｓＰＬＡ２阻害作用を有するピロロ［１，２−ａ］ピラジン誘導体
CN1302300A (zh)	1998-05-21	2001-07-04	盐野义制药株式会社	吡咯并[1,2－b]哒嗪sPLA2抑制剂
DE69931963D1 (de)	1998-10-14	2006-07-27	Shionogi & Co	Spla2-inhibitoren zur behandlung von ischämischen reperfusionsschäden
JP4636521B2 (ja)	1999-07-19	2011-02-23	塩野義製薬株式会社	ｓＰＬＡ２阻害作用を有する三環系化合物
JP4636522B2 (ja)	1999-08-02	2011-02-23	塩野義製薬株式会社	ｓＰＬＡ２阻害作用を有する三環式化合物
US6787545B1 (en)	1999-08-23	2004-09-07	Shiongi & Co., Ltd.	Pyrrolotriazine derivatives having spla2-inhibitory activities
ES2171116B1 (es) *	2000-04-14	2003-08-01	Esteve Quimica Sa	Procedimiento para la obtencion de derivados de (((piridil sustituido)metil)tio)bencimidazol.
US6967200B2 (en)	2000-06-29	2005-11-22	Shionogi & Co., Ltd.	Remedies for cirrhosis
JPWO2002000621A1 (ja)	2000-06-29	2004-04-22	塩野義製薬株式会社	Ｘ型ｓＰＬＡ２阻害作用を有する化合物
TWI314457B (id)	2001-03-19	2009-09-11	Shionogi & Co
US7076539B2 (en) *	2001-07-30	2006-07-11	Hewlett-Packard Development Company, L.P.	Network connectivity establishment at user log-in
WO2003101177A2 (en) *	2002-06-04	2003-12-11	Sequenom, Inc.	Diagnosing predisposition to fat deposition and therapeutic methods for reducing fat deposition and treatment of associated conditions
AUPS282602A0 (en)	2002-06-07	2002-06-27	Garvan Institute Of Medical Research	Method of inhibiting cell proliferation
US20050014158A1 (en) *	2002-06-27	2005-01-20	Adam Gail Isabel Reid	Therapeutic methods for reducing fat deposition and treating associated conditions
WO2004002295A2 (en) *	2002-06-27	2004-01-08	Sequenom, Inc.	Diagnosing predisposition to fat deposition and associated condition
CN101925588B (zh) *	2008-01-25	2014-01-15	先正达参股股份有限公司	用作杀虫剂的2-氰基苯基磺酰胺衍生物
SG175390A1 (en)	2009-04-29	2011-12-29	Amarin Corp Plc	Pharmaceutical compositions comprising epa and a cardiovascular agent and methods of using the same
CN105017134A (zh) *	2015-07-26	2015-11-04	陈吉美	一种4-吡啶丙烯酸的制备方法
CN117285547A (zh)	2018-02-15	2023-12-26	弗特克斯药品有限公司	作为cftr的调节剂的大环化合物、其药物组合物、它们的用途和制备方法
TWI867024B (zh)	2019-08-14	2024-12-21	美商維泰克斯製藥公司	囊腫纖維化跨膜傳導調節蛋白之調節劑
MX2022001828A (es)	2019-08-14	2022-06-08	Vertex Pharma	Formas cristalinas de moduladores del regulador de conductancia transmembrana de la fibrosis quistica (cftr).
TW202120517A (zh)	2019-08-14	2021-06-01	美商維泰克斯製藥公司	製備cftr調節劑之方法
EP4225737A1 (en) *	2020-10-07	2023-08-16	Vertex Pharmaceuticals Incorporated	Modulators of cystic fibrosis transmembrane conductance regulator
WO2022125826A1 (en)	2020-12-10	2022-06-16	Vertex Pharmaceuticals Incorporated	Methods of treatment for cystic fibrosis

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3616681A1 (de) *	1986-05-16	1987-11-19	Bayer Ag	1-aralkylpyrazole
JPH02229169A (ja) *	1989-03-01	1990-09-11	Takeda Chem Ind Ltd	ピラゾロン誘導体
JPH02229168A (ja) *	1989-03-01	1990-09-11	Takeda Chem Ind Ltd	ピラゾロン誘導体
EP0465913B1 (en) *	1990-07-10	1997-09-10	Ishihara Sangyo Kaisha, Ltd.	Diaminotrifluoromethylpyrimidine derivatives, process for their production and phospholipase A2 inhibitor containing them
EP0539034A1 (en) *	1991-10-22	1993-04-28	Konica Corporation	A novel photographic cyan coupler
US5541213A (en) *	1993-06-24	1996-07-30	Eisai Co., Ltd.	Propenoic acid derivatives diazole propenoic acid compounds which have useful pharmaceutical utility
US5466823A (en) *	1993-11-30	1995-11-14	G.D. Searle & Co.	Substituted pyrazolyl benzenesulfonamides
US5500439A (en) *	1993-12-09	1996-03-19	Alteon Inc.	Aminopyrazoles
US5559137A (en) *	1994-05-16	1996-09-24	Smithkline Beecham Corp.	Compounds
US5486534A (en) *	1994-07-21	1996-01-23	G. D. Searle & Co.	3,4-substituted pyrazoles for the treatment of inflammation

1997
- 1997-11-27 ID IDP973793A patent/ID18983A/id unknown
- 1997-12-01 AU AU53655/98A patent/AU5365598A/en not_active Abandoned
- 1997-12-01 BR BR9713993-9A patent/BR9713993A/pt unknown
- 1997-12-01 HU HU0000292A patent/HUP0000292A3/hu unknown
- 1997-12-01 JP JP52568198A patent/JP2002515053A/ja not_active Withdrawn
- 1997-12-01 WO PCT/US1997/021795 patent/WO1998024437A1/en not_active Application Discontinuation
- 1997-12-01 KR KR1019990704898A patent/KR20000057366A/ko not_active Application Discontinuation
- 1997-12-01 IL IL13020297A patent/IL130202A0/xx unknown
- 1997-12-01 CA CA002274048A patent/CA2274048A1/en not_active Abandoned
- 1997-12-01 PE PE1997001083A patent/PE20599A1/es not_active Application Discontinuation
- 1997-12-02 ES ES97309701T patent/ES2160897T3/es not_active Expired - Lifetime
- 1997-12-02 AT AT97309701T patent/ATE203985T1/de not_active IP Right Cessation
- 1997-12-02 CO CO97070453A patent/CO4910169A1/es unknown
- 1997-12-02 PT PT97309701T patent/PT846687E/pt unknown
- 1997-12-02 EP EP97309701A patent/EP0846687B1/en not_active Expired - Lifetime
- 1997-12-02 DE DE69706027T patent/DE69706027T2/de not_active Expired - Fee Related
- 1997-12-02 DK DK97309701T patent/DK0846687T3/da active
- 1997-12-03 US US08/984,261 patent/US5972972A/en not_active Expired - Fee Related
- 1997-12-03 AR ARP970105678A patent/AR010743A1/es unknown
- 1997-12-03 ZA ZA9710878A patent/ZA9710878B/xx unknown
- 1997-12-05 TW TW086118237A patent/TW432051B/zh not_active IP Right Cessation
1998
- 1998-12-10 HK HK98113166A patent/HK1011865A1/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
AU5365598A (en)	1998-06-29
EP0846687A1 (en)	1998-06-10
PT846687E (pt)	2001-12-28
CO4910169A1 (es)	2000-04-24
DK0846687T3 (da)	2001-10-08
EP0846687B1 (en)	2001-08-08
DE69706027D1 (de)	2001-09-13
HUP0000292A2 (hu)	2001-04-28
AR010743A1 (es)	2000-07-12
IL130202A0 (en)	2000-06-01
DE69706027T2 (de)	2002-03-14
US5972972A (en)	1999-10-26
KR20000057366A (ko)	2000-09-15
TW432051B (en)	2001-05-01
ZA9710878B (en)	1999-06-03
WO1998024437A1 (en)	1998-06-11
HUP0000292A3 (en)	2002-01-28
BR9713993A (pt)	2000-02-08
HK1011865A1 (en)	1999-07-23
PE20599A1 (es)	1999-03-05
ATE203985T1 (de)	2001-08-15
JP2002515053A (ja)	2002-05-21
CA2274048A1 (en)	1998-06-11
ES2160897T3 (es)	2001-11-16

Publication	Publication Date	Title
ID18983A (id)	1998-05-28	Pirazola sebagai inhibitor sekresi fosfolipase a2 non-pankreas pada manusia
DE69633991T2 (de)	2005-04-21	CMDA-Basisstaionssender
DE69720097D1 (de)	2003-04-30	Entwicklungsgerät
DE69735996D1 (de)	2006-07-06	Menschlicher bikunin
NO973216D0 (no)	1997-07-10	Substituerte oksazolidin-calpain- og/eller cathepsin B-inhibitorer
DE69738634D1 (de)	2008-05-29	Bildselektions- und anzeigegerät
DE69715313D1 (de)	2002-10-17	Entwicklungsgerät
DE69821408D1 (de)	2004-03-11	Multiplikationsverfahren und -vorrichtung
PT927183E (pt)	2004-12-31	Inibidores espirociclicos de metaloproteases
NO995324L (no)	1999-12-28	Baerer for gjenstander og emne for denne
NO963184D0 (no)	1996-07-30	Kompressoranordning
DE69834441D1 (de)	2006-06-08	Ausgabevorrichtung
DE69814039D1 (de)	2003-06-05	Ausstossvorrichtung
DE69815269D1 (de)	2003-07-10	Druckklebrige Folien
ATE192257T1 (de)	2000-05-15	Anzeigevorrichtung und-anordnung
NO983556L (no)	1998-08-03	Formulering og anvendelse
FR2772160B1 (fr)	2001-10-05	Circuit de calcul de la transformee de fourier rapide et de la transformee de fourier rapide inverse
DE69726402D1 (de)	2004-01-08	Filmentwicklungsgerät
EE200000352A (et)	2001-08-15	Elektrilist skeemi sisaldava seadmega seotud konstruktsioonid ja meetod
EP1007548A4 (en)	2002-07-03	THROMBIN INHIBITOR FROM TSE-TSE FLY
DK0895588T3 (da)	2003-10-27	Undersøgelsesanordning
DE59700141D1 (de)	1999-06-02	Zweiteiliger transparenter Zeiger
FI972010A0 (fi)	1997-05-13	Arrangemang i en borrningsanordning
NO20003054L (no)	2000-07-31	Kirurgisk anordning
KR970025030U (ko)	1997-06-20	전원 특성 시험장치