HUT77518A - Kompetitív progeszteron-antagonisták szükség szerinti női termékenységszabályozásra - Google Patents

Kompetitív progeszteron-antagonisták szükség szerinti női termékenységszabályozásra

Info

Publication number: HUT77518A
Authority: HU; Hungary
Prior art keywords: progesterone antagonists; competitive progesterone; female fertility; dosage; regulating female
Prior art date: 1994-10-24

Application number

HU9702177A

Other languages

English (en)

Other versions

HU226566B1 (en

Inventor

Kristof Chwalisz

Walter Klemann

Karin Schmidt-Gollwitzer

Klaus Stöckemann

Original Assignee

Schering Aktiengesellschaft

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-10-24

Filing date

1995-10-24

Publication date

1998-05-28

1995-10-24 Application filed by Schering Aktiengesellschaft filed Critical Schering Aktiengesellschaft

1998-05-28 Publication of HUT77518A publication Critical patent/HUT77518A/hu

2009-04-28 Publication of HU226566B1 publication Critical patent/HU226566B1/hu

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
- A61K31/569—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones

Landscapes

Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Epidemiology (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Endocrinology (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Diabetes (AREA)
Gynecology & Obstetrics (AREA)
Reproductive Health (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Steroid Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Investigating Or Analysing Biological Materials (AREA)
Peptides Or Proteins (AREA)

HU9702177A 1994-10-24 1995-10-24 Use of competitive progesterone antagonists for producing pharmaceutical compositions for regulating female fertility as required HU226566B1 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE4438820		1994-10-24
PCT/EP1995/004191 WO1996012494A1 (de)	1994-10-24	1995-10-24	Kompetitive progesteronantagonisten zur bedarfsorientierten weiblichen fertilitätskontrolle

Publications (2)

Publication Number	Publication Date
HUT77518A true HUT77518A (hu)	1998-05-28
HU226566B1 HU226566B1 (en)	2009-04-28

Family

ID=6532105

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HU9702177A HU226566B1 (en)	1994-10-24	1995-10-24	Use of competitive progesterone antagonists for producing pharmaceutical compositions for regulating female fertility as required

Country Status (25)

Country	Link
US (1)	US6143754A (hu)
EP (1)	EP0787002B1 (hu)
JP (1)	JPH10507461A (hu)
KR (1)	KR970706827A (hu)
CN (1)	CN1211087C (hu)
AT (1)	ATE347894T1 (hu)
AU (1)	AU707235B2 (hu)
BG (1)	BG62877B1 (hu)
BR (1)	BR9509478A (hu)
CA (1)	CA2203541A1 (hu)
CZ (1)	CZ290690B6 (hu)
DE (1)	DE59511071D1 (hu)
DK (1)	DK0787002T3 (hu)
ES (1)	ES2279515T3 (hu)
FI (1)	FI971742A (hu)
HU (1)	HU226566B1 (hu)
IL (1)	IL115738A (hu)
NO (1)	NO314437B1 (hu)
NZ (1)	NZ295365A (hu)
PL (1)	PL319869A1 (hu)
PT (1)	PT787002E (hu)
RO (1)	RO120606B1 (hu)
SK (1)	SK283662B6 (hu)
WO (1)	WO1996012494A1 (hu)
ZA (1)	ZA959008B (hu)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE19745085A1 (de) *	1997-10-11	1999-04-15	Jenapharm Gmbh	11ß-Benzaldoxim-9alpha,10alpha-epoxy-estr-4-en-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Präparate
DE19809845A1 (de) *	1998-03-03	1999-09-09	Jenapharm Gmbh	S-substituierte 11beta-Benzaldoxim-estra-4,9-dien-kohlensäurethiolester, Verfahren zu deren Herstellung und diese Verbindungen enthaltende pharmazeutische Zubereitungen
EP1605924B1 (en) *	1999-08-31	2008-11-05	Bayer Schering Pharma Aktiengesellschaft	Mesoprogestins (progesterone receptor modulators) as a component of compositions for hormone replacement therapy (hrt)
IL148415A0 (en) *	1999-08-31	2002-09-12	Jenapharm Gmbh	Mesoprogestins (progesterone receptor modulators) as a component of female contraceptives
US7629334B1 (en)	1999-08-31	2009-12-08	Bayer Schering Pharma Aktiengesellschaft	Mesoprogrestins (progesterone receptor modulations) as a component of compositions for hormone replacement therapy (HRT)
DE102005050729A1 (de) *	2005-10-19	2007-04-26	Schering Ag	Verfahren zur präventiven bedarfsweisen hormonalen Kontrazeption
JP2011507853A (ja) *	2007-12-20	2011-03-10	テバウィメンズヘルスインコーポレイテッド	緊急避妊のための投与量レジメンならびに薬学的組成物およびパッケージ
ES2574999T3 (es) *	2009-04-14	2016-06-23	Laboratoire Hra-Pharma	Método para la contracepción a demanda usando levonorgestrel o norgestrel
PL2419108T3 (pl)	2009-04-14	2017-08-31	Laboratoire Hra Pharma	Sposób antykoncepcji na żądanie
MX2015016121A (es)	2013-05-23	2016-03-31	Bayer Pharma AG	Composicion farmaceutica, su uso y regimen de administracion para contracepcion a demanda.
AU2015350241B2 (en)	2014-11-17	2021-05-20	Context Biopharma Inc.	Onapristone extended-release compositions and methods
EP3353148A4 (en)	2015-09-25	2019-04-24	Context Biopharma Inc.	PROCESS FOR THE PRODUCTION OF ONAPRISTONE INTERMEDIATE PRODUCTS
US10548905B2 (en)	2015-12-15	2020-02-04	Context Biopharma Inc.	Amorphous onapristone compositions and methods of making the same
US20180148471A1 (en)	2016-11-30	2018-05-31	Arno Therapeutics, Inc.	Methods for onapristone synthesis dehydration and deprotection

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5439913A (en) *	1992-05-12	1995-08-08	Schering Aktiengesellschaft	Contraception method using competitive progesterone antagonists and novel compounds useful therein

1995
- 1995-10-24 ES ES95937845T patent/ES2279515T3/es not_active Expired - Lifetime
- 1995-10-24 CN CNB951958178A patent/CN1211087C/zh not_active Expired - Fee Related
- 1995-10-24 RO RO97-00635A patent/RO120606B1/ro unknown
- 1995-10-24 PL PL95319869A patent/PL319869A1/xx unknown
- 1995-10-24 PT PT95937845T patent/PT787002E/pt unknown
- 1995-10-24 WO PCT/EP1995/004191 patent/WO1996012494A1/de active IP Right Grant
- 1995-10-24 DE DE59511071T patent/DE59511071D1/de not_active Expired - Fee Related
- 1995-10-24 CA CA002203541A patent/CA2203541A1/en not_active Abandoned
- 1995-10-24 SK SK518-97A patent/SK283662B6/sk unknown
- 1995-10-24 DK DK95937845T patent/DK0787002T3/da active
- 1995-10-24 IL IL11573895A patent/IL115738A/en not_active IP Right Cessation
- 1995-10-24 EP EP95937845A patent/EP0787002B1/de not_active Expired - Lifetime
- 1995-10-24 CZ CZ19971180A patent/CZ290690B6/cs not_active IP Right Cessation
- 1995-10-24 NZ NZ295365A patent/NZ295365A/xx unknown
- 1995-10-24 HU HU9702177A patent/HU226566B1/hu not_active IP Right Cessation
- 1995-10-24 JP JP8513655A patent/JPH10507461A/ja active Pending
- 1995-10-24 BR BR9509478A patent/BR9509478A/pt active Search and Examination
- 1995-10-24 ZA ZA959008A patent/ZA959008B/xx unknown
- 1995-10-24 AT AT95937845T patent/ATE347894T1/de not_active IP Right Cessation
- 1995-10-24 AU AU38696/95A patent/AU707235B2/en not_active Ceased
1997
- 1997-04-21 BG BG101427A patent/BG62877B1/bg unknown
- 1997-04-23 FI FI971742A patent/FI971742A/fi unknown
- 1997-04-23 NO NO19971869A patent/NO314437B1/no unknown
- 1997-04-24 KR KR1019970702695A patent/KR970706827A/ko active Search and Examination
1999
- 1999-03-22 US US09/273,485 patent/US6143754A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
EP0787002A1 (de)	1997-08-06
MX9703018A (es)	1997-10-31
ZA959008B (en)	1996-09-16
NO314437B1 (no)	2003-03-24
FI971742A0 (fi)	1997-04-23
PT787002E (pt)	2007-03-30
US6143754A (en)	2000-11-07
SK283662B6 (sk)	2003-11-04
CN1211087C (zh)	2005-07-20
CA2203541A1 (en)	1996-05-02
AU3869695A (en)	1996-05-15
NO971869L (no)	1997-04-23
DE59511071D1 (de)	2007-01-25
KR970706827A (ko)	1997-12-01
IL115738A0 (en)	1996-01-19
FI971742A (fi)	1997-04-23
JPH10507461A (ja)	1998-07-21
SK51897A3 (en)	1997-09-10
WO1996012494A1 (de)	1996-05-02
BG62877B1 (bg)	2000-10-31
BG101427A (en)	1997-11-28
CZ290690B6 (cs)	2002-09-11
HU226566B1 (en)	2009-04-28
AU707235B2 (en)	1999-07-08
NO971869D0 (no)	1997-04-23
PL319869A1 (en)	1997-09-01
ATE347894T1 (de)	2007-01-15
DK0787002T3 (da)	2007-04-10
RO120606B1 (ro)	2006-05-30
BR9509478A (pt)	1997-09-30
CZ118097A3 (en)	1997-07-16
NZ295365A (en)	1999-07-29
CN1161649A (zh)	1997-10-08
IL115738A (en)	2002-05-23
ES2279515T3 (es)	2007-08-16
EP0787002B1 (de)	2006-12-13

Publication	Publication Date	Title
NZ295365A (en)	1999-07-29	Competitive progesterone antagonists for regulating female fertility as required
ATE217192T1 (de)	2002-05-15	Kombinationsprodukt zur kontrazeption enthaltend progesteronantagonisten und gestagenen
NZ234051A (en)	1991-09-25	Treating post-menopausal disorders using an estrogenic compound mixed with a compound having progestational activity
GB9416442D0 (en)	1994-10-05	Therapeutic heterocycles
BG101553A (en)	1998-09-30	Progesterone antagonist and antiestrogenous active compounds of general application for female contraceptives
HUT75930A (en)	1997-05-28	Progesterone antagonists useful preparing medicaments for treating dysfunctional uterine bleeding
MX9702162A (es)	1997-06-28	Procedimiento para hacer unidades de dosis mediante granulacion en humedo.
IL78017A (en)	1989-06-30	Sustained release tablets of theophylline
IL109076A0 (en)	1994-06-24	Imidazolo-quinoxalinones, their preparation and pharmaceutical compositions containing them
GB2165750A (en)	1986-04-23	Contraceptive synergistic association
ES8802372A1 (es)	1988-05-16	Procedimiento para preparar un agente que contiene tirosina o un derivado de tirosina como sustancia activa para mejorar la fecundidad de mamiferos.
EP0301850A3 (en)	1990-10-31	Lhrh antagonist analogs and 19-nor-progestational steroids for therapy
HUP9900313A1 (hu)	1999-06-28	Antiösztrogének alkalmazása hím nemzőképesség szabályozására
JPS57185567A (en)	1982-11-15	Alteration requesting system for system
JPS5591012A (en)	1980-07-10	Decentralized bus system
JPS5414120A (en)	1979-02-02	Initial setting system for device
Crist	1974	Post-coital estrogen
ES395365A1 (es)	1974-07-16	Procedimiento para la obtencion de agentes anticonceptivos.
JPS55124825A (en)	1980-09-26	Bus control unit
UA23363A (uk)	1998-08-31	Спосіб лікування запальних процесів придатків матки
UA10995C2 (uk)	1996-12-25	Препарат "hейтрам" для лікуваhhя hеоhатальhих діарей у телят

Legal Events

Date	Code	Title	Description
2009-07-28	MM4A	Lapse of definitive patent protection due to non-payment of fees