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HUP9902897A2 - Mikrokapszulázott fluorozott gázok leképező szerként történő alkalmazásra - Google Patents

Mikrokapszulázott fluorozott gázok leképező szerként történő alkalmazásra

Info

Publication number
HUP9902897A2
HUP9902897A2 HU9902897A HUP9902897A HUP9902897A2 HU P9902897 A2 HUP9902897 A2 HU P9902897A2 HU 9902897 A HU9902897 A HU 9902897A HU P9902897 A HUP9902897 A HU P9902897A HU P9902897 A2 HUP9902897 A2 HU P9902897A2
Authority
HU
Hungary
Prior art keywords
microparticle
incorporating
imaging agents
imaging
fluorinated gases
Prior art date
Application number
HU9902897A
Other languages
English (en)
Inventor
Howard Bernstein
Henry T. Brush
Edith Mathiowitz
Julie Ann Straub
Richard E. Wing
Original Assignee
Acusphere, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27086474&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUP9902897(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US08/611,248 external-priority patent/US5611344A/en
Application filed by Acusphere, Inc. filed Critical Acusphere, Inc.
Publication of HUP9902897A2 publication Critical patent/HUP9902897A2/hu
Publication of HUP9902897A3 publication Critical patent/HUP9902897A3/hu
Publication of HU226714B1 publication Critical patent/HU226714B1/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/48—Diagnostic techniques
    • A61B8/481—Diagnostic techniques involving the use of contrast agents, e.g. microbubbles introduced into the bloodstream
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Acoustics & Sound (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Treatments Of Macromolecular Shaped Articles (AREA)

Abstract

A találmány tárgya flűőrőzőtt gázők, különösen perflűőrőzőttszénhidrőgének, pl. őktaflűőr-prőpán beépítése szintetikűs pőlimermikrőrészecskékbe, amely eljárás jelentősen megnöveli azechőgenicitást a beépített levegőjű mikrőrészecskékkelösszehasőnlítva. A mikrőkapszűlázőtt perflűőrőzőtt szénhidrőgénelőállítására az átmérőt úgy választják meg, hőgy az megfelelő legyena leképezendő célszövetekhez, pl. intravénás vagy őrális adagőlásra. Atalálmány tárgyát képezi tővábbá a nyálkás felületek főkőzőttleképezését szőlgáló biőadhezív mikrőrészecskék előállítására. ŕ
HU9902897A 1996-03-05 1997-02-27 Microencapsulated fluorinated gases for use as imaging agents HU226714B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/611,248 US5611344A (en) 1996-03-05 1996-03-05 Microencapsulated fluorinated gases for use as imaging agents
US08/745,676 US5853698A (en) 1996-03-05 1996-11-08 Method for making porous microparticles by spray drying
PCT/US1997/003117 WO1997032609A2 (en) 1996-03-05 1997-02-27 Microencapsulated fluorinated gases for use as imaging agents

Publications (3)

Publication Number Publication Date
HUP9902897A2 true HUP9902897A2 (hu) 2000-01-28
HUP9902897A3 HUP9902897A3 (en) 2000-03-28
HU226714B1 HU226714B1 (en) 2009-07-28

Family

ID=27086474

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9902897A HU226714B1 (en) 1996-03-05 1997-02-27 Microencapsulated fluorinated gases for use as imaging agents

Country Status (21)

Country Link
US (1) US6132699A (hu)
EP (1) EP0904113B1 (hu)
JP (1) JP3178724B2 (hu)
AT (1) ATE266426T1 (hu)
AU (1) AU721209B2 (hu)
BR (1) BR9707936B1 (hu)
CA (1) CA2247151C (hu)
CZ (1) CZ281298A3 (hu)
DE (1) DE69729088T2 (hu)
DK (1) DK0904113T3 (hu)
ES (1) ES2221687T3 (hu)
HK (1) HK1020428A1 (hu)
HU (1) HU226714B1 (hu)
ID (1) ID17753A (hu)
IL (1) IL126073A (hu)
MY (1) MY124549A (hu)
NO (1) NO312940B1 (hu)
NZ (1) NZ331460A (hu)
PT (1) PT904113E (hu)
TW (1) TWI246426B (hu)
WO (1) WO1997032609A2 (hu)

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US20060165606A1 (en) 1997-09-29 2006-07-27 Nektar Therapeutics Pulmonary delivery particles comprising water insoluble or crystalline active agents
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US6223455B1 (en) * 1999-05-03 2001-05-01 Acusphere, Inc. Spray drying apparatus and methods of use
KR100769224B1 (ko) * 1999-12-10 2007-10-22 아이싸이언스 인터벤셔날 코포레이션 안 질환의 치료방법
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US6919068B2 (en) * 2002-05-17 2005-07-19 Point Biomedical Corporation Method of preparing gas-filled polymer matrix microparticles useful for echographic imaging
US20040121003A1 (en) * 2002-12-19 2004-06-24 Acusphere, Inc. Methods for making pharmaceutical formulations comprising deagglomerated microparticles
US6962006B2 (en) * 2002-12-19 2005-11-08 Acusphere, Inc. Methods and apparatus for making particles using spray dryer and in-line jet mill
US20050171425A1 (en) * 2004-01-16 2005-08-04 Phantoms-By-Design Medical devices having MRI-enhancing encapsulated fluids
MXPA06014111A (es) * 2004-06-04 2007-03-07 Acusphere Inc Formulacion de dosificacion de agente de contraste de ultrasonido.
US8012457B2 (en) 2004-06-04 2011-09-06 Acusphere, Inc. Ultrasound contrast agent dosage formulation
EP1973523A2 (en) * 2005-12-15 2008-10-01 Acusphere, Inc. Processes for making particle-based pharmaceutical formulations for pulmonary or nasal administration
EP1978933A2 (en) * 2005-12-15 2008-10-15 Acusphere, Inc. Processes for making particle-based pharmaceutical formulations for oral administration
DE102008045152A1 (de) * 2008-07-09 2010-01-14 Universität Duisburg-Essen Künstliche Sauerstoffträger und ihre Verwendung
KR101061224B1 (ko) * 2008-10-08 2011-08-31 포항공과대학교 산학협력단 Ｘ 선을 이용한 유동정보 측정용 캡슐
NL2003660C2 (en) * 2009-10-16 2011-04-19 Giskit B V Composition and method for medical imaging of body cavities.
JP2011140527A (ja) * 2011-04-20 2011-07-21 Acusphere Inc 超音波造影剤の投薬処方物

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Also Published As

Publication number Publication date
MY124549A (en) 2006-06-30
ES2221687T3 (es) 2005-01-01
HK1020428A1 (en) 2000-04-20
DK0904113T3 (da) 2004-08-30
AU2139297A (en) 1997-09-22
WO1997032609A2 (en) 1997-09-12
CA2247151C (en) 2008-05-20
ATE266426T1 (de) 2004-05-15
NZ331460A (en) 1998-12-23
IL126073A (en) 2002-02-10
AU721209B2 (en) 2000-06-29
WO1997032609A3 (en) 1998-01-29
ID17753A (id) 1998-01-22
HUP9902897A3 (en) 2000-03-28
TWI246426B (en) 2006-01-01
NO984089L (no) 1998-09-04
HU226714B1 (en) 2009-07-28
NO312940B1 (no) 2002-07-22
PT904113E (pt) 2004-09-30
EP0904113B1 (en) 2004-05-12
IL126073A0 (en) 1999-05-09
CZ281298A3 (cs) 1999-01-13
CA2247151A1 (en) 1997-09-12
DE69729088T2 (de) 2005-05-12
NO984089D0 (no) 1998-09-04
EP0904113A2 (en) 1999-03-31
JP2000501745A (ja) 2000-02-15
US6132699A (en) 2000-10-17
BR9707936B1 (pt) 2010-12-14
JP3178724B2 (ja) 2001-06-25
BR9707936A (pt) 2000-01-04
DE69729088D1 (de) 2004-06-17

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