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HUP9900902A2 - Vegyületek és eljárások a tuberkulózis diagnosztikájához és immunterápiájára - Google Patents

Vegyületek és eljárások a tuberkulózis diagnosztikájához és immunterápiájára

Info

Publication number
HUP9900902A2
HUP9900902A2 HU9900902A HUP9900902A HUP9900902A2 HU P9900902 A2 HUP9900902 A2 HU P9900902A2 HU 9900902 A HU9900902 A HU 9900902A HU P9900902 A HUP9900902 A HU P9900902A HU P9900902 A2 HUP9900902 A2 HU P9900902A2
Authority
HU
Hungary
Prior art keywords
immunotherapy
tuberculosis
diagnosis
compounds
methods
Prior art date
Application number
HU9900902A
Other languages
English (en)
Inventor
Antonio Campos-Neto
Davin C. Dillon
Raymond Houghton
Steven G. Reed
Yasir A. Skeiky
Daniel R. Twardzik
Thomas H. Vedvick
Original Assignee
Corixa Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27541835&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUP9900902(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Corixa Corporation filed Critical Corixa Corporation
Publication of HUP9900902A2 publication Critical patent/HUP9900902A2/hu
Publication of HUP9900902A3 publication Critical patent/HUP9900902A3/hu
Publication of HU225979B1 publication Critical patent/HU225979B1/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Public Health (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Cell Biology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

A találmány tárgyát Mycőbacteriűm tűbercűlősis fertőzés kiműtatása,kezelése és megelőzése képezi. Közelebbről, a találmány tárgyát őlyanpőlipeptidek képezik, amelyek Mycőbacteriűm tűbercűlősis antigénttartalmaznak, vagy annak egy részét vagy más variánsát tartalmazzák,valamint az ilyen pőlipeptidek alkalmazása Mycőbacteriűm tűbercűlősisfertőzés kiműtatására és alkalmazásűk a fertőzés elleni védőőltásban. ŕ
HU9900902A 1995-09-01 1996-08-30 Compounds and methods for immunotherapy and diagnosis of tuberculosis HU225979B1 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US52343695A 1995-09-01 1995-09-01
US53363495A 1995-09-22 1995-09-22
US62087496A 1996-03-22 1996-03-22
US65968396A 1996-06-05 1996-06-05
US68057496A 1996-07-12 1996-07-12
PCT/US1996/014674 WO1997009428A2 (en) 1995-09-01 1996-08-30 Compounds and methods for immunotherapy and diagnosis of tuberculosis

Publications (3)

Publication Number Publication Date
HUP9900902A2 true HUP9900902A2 (hu) 1999-07-28
HUP9900902A3 HUP9900902A3 (en) 2001-03-28
HU225979B1 HU225979B1 (en) 2008-02-28

Family

ID=27541835

Family Applications (2)

Application Number Title Priority Date Filing Date
HU9900902A HU225979B1 (en) 1995-09-01 1996-08-30 Compounds and methods for immunotherapy and diagnosis of tuberculosis
HU0900047A HU227778B1 (en) 1995-09-01 1996-08-30 Immogen peptid of m. tuberculosis origin, therapeutic and diagnostic use thereof

Family Applications After (1)

Application Number Title Priority Date Filing Date
HU0900047A HU227778B1 (en) 1995-09-01 1996-08-30 Immogen peptid of m. tuberculosis origin, therapeutic and diagnostic use thereof

Country Status (24)

Country Link
EP (5) EP1203817B9 (hu)
JP (5) JP4382160B2 (hu)
KR (1) KR100433750B1 (hu)
CN (1) CN1117149C (hu)
AT (5) ATE323165T1 (hu)
AU (1) AU727602B2 (hu)
BR (2) BR9612997B1 (hu)
CA (3) CA2230885C (hu)
CY (2) CY2570B1 (hu)
CZ (3) CZ300953B6 (hu)
DE (4) DE69636487T2 (hu)
DK (4) DK1347055T3 (hu)
ES (4) ES2324529T3 (hu)
HK (1) HK1059282A1 (hu)
HU (2) HU225979B1 (hu)
IL (1) IL123506A (hu)
MX (1) MX9801638A (hu)
NO (4) NO324372B1 (hu)
NZ (1) NZ319377A (hu)
PL (1) PL186774B1 (hu)
PT (4) PT851927E (hu)
SI (1) SI0851927T1 (hu)
TR (5) TR200806258T2 (hu)
WO (1) WO1997009428A2 (hu)

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US6641814B1 (en) 1997-04-02 2003-11-04 Statens Serum Institut Nucleic acids fragments and polypeptide fragments derived from M. tuberculosis
US6991797B2 (en) 1993-07-02 2006-01-31 Statens Serum Institut M. tuberculosis antigens
US6290969B1 (en) * 1995-09-01 2001-09-18 Corixa Corporation Compounds and methods for immunotherapy and diagnosis of tuberculosis
US6458366B1 (en) 1995-09-01 2002-10-01 Corixa Corporation Compounds and methods for diagnosis of tuberculosis
US6592877B1 (en) 1995-09-01 2003-07-15 Corixa Corporation Compounds and methods for immunotherapy and diagnosis of tuberculosis
TR199901569T2 (xx) * 1996-10-11 2000-12-21 Corixa Corporation T�berk�lozun te�hisi i�in bile�ikler ve y�ntemler.
US6627198B2 (en) 1997-03-13 2003-09-30 Corixa Corporation Fusion proteins of Mycobacterium tuberculosis antigens and their uses
US6544522B1 (en) 1998-12-30 2003-04-08 Corixa Corporation Fusion proteins of mycobacterium tuberculosis antigens and their uses
US6350456B1 (en) 1997-03-13 2002-02-26 Corixa Corporation Compositions and methods for the prevention and treatment of M. tuberculosis infection
US6982085B2 (en) 1997-04-02 2006-01-03 Statens Serum Institut TB diagnostic based on antigens from M. tuberculosis
EP1449922B1 (en) * 1997-04-02 2007-08-15 Statens Serum Institut Nucleic acid fragments and polypeptide fragments derived from M. tuberculosis
US7037510B2 (en) 1997-04-18 2006-05-02 Statens Serum Institut Hybrids of M. tuberculosis antigens
US6555653B2 (en) 1997-05-20 2003-04-29 Corixa Corporation Compounds for diagnosis of tuberculosis and methods for their use
US6613881B1 (en) * 1997-05-20 2003-09-02 Corixa Corporation Compounds for immunotherapy and diagnosis of tuberculosis and methods of their use
US7087713B2 (en) 2000-02-25 2006-08-08 Corixa Corporation Compounds and methods for diagnosis and immunotherapy of tuberculosis
AU8123898A (en) * 1997-07-16 1999-02-10 Institut Pasteur A polynucleotide functionally coding for the lhp protein from mycobacterium tuberculosis, its biologically active derivative fragments, as well as metho ds usingthe same
EP1029053A1 (en) * 1997-11-10 2000-08-23 Statens Seruminstitut Nucleic acid fragments and polypeptide fragments derived from mycobacterium tuberculosis
EP1484405A1 (en) * 1997-11-10 2004-12-08 Statens Serum Institut Nucleic acid fragments and polypeptide fragments derived from M. Tuberculosis
HU228354B1 (en) * 1998-04-07 2013-03-28 Corixa Corp Fusion proteins of mycobacterium tuberculosis antigens and their uses
GB9808720D0 (en) * 1998-04-23 1998-06-24 Smithkline Beecham Biolog Novel compounds
CA2348475A1 (en) * 1998-11-04 2000-05-11 Isis Innovation Limited Tuberculosis diagnostic test
US6465633B1 (en) 1998-12-24 2002-10-15 Corixa Corporation Compositions and methods of their use in the treatment, prevention and diagnosis of tuberculosis
AU2594500A (en) * 1998-12-24 2000-07-31 Corixa Corporation Methods for using mycobacterium tuberculosis molecules as immunological adjuvants
CA2372583C (en) * 1999-05-04 2012-07-10 The Public Health Research Institute Of The City Of New York, Inc. Proteins expressed by mycobacterium tuberculosis and not by bcg and their use as diagnostic reagents and vaccines
US7009042B1 (en) * 1999-10-07 2006-03-07 Corixa Corporation Methods of using a Mycobacterium tuberculosis coding sequence to facilitate stable and high yield expression of the heterologous proteins
US6316205B1 (en) 2000-01-28 2001-11-13 Genelabs Diagnostics Pte Ltd. Assay devices and methods of analyte detection
EP1542732B1 (en) 2000-06-20 2009-09-16 Corixa Corporation Fusion proteins of mycobacterium tuberculosis
AU2003213118A1 (en) 2002-02-15 2003-09-09 Corixa Corporation Fusion proteins of mycobacterium tuberculosis
ITRM20040091A1 (it) 2004-02-19 2004-05-19 Istituto Naz Per Le Malattie Test immunologico rapido per la diagnosi ed il monitoraggio dell'infezione tubercolare.
FI119445B (fi) * 2004-10-29 2008-11-14 Waertsilae Finland Oy Polttomoottorin polttoaineen syöttöjärjestelmän paineen värähtelyn vaimennin
EA012037B1 (ru) 2004-11-16 2009-06-30 Круселл Холланд Б.В. Поливалентные вакцины, содержащие рекомбинантные вирусные векторы
US8470338B2 (en) 2005-04-29 2013-06-25 Glaxosmithkline Biologicals, S.A. Method for preventing or treating M tuberculosis infection
FR2952058B1 (fr) * 2009-10-29 2013-10-04 Centre Nat Rech Scient Procede de ligation native de polypeptides
UA110103C2 (uk) 2010-01-27 2015-11-25 Ґлаксосмітклайн Байолоджікалз С.А. Модифікований туберкульозний антиген
MX344280B (es) 2010-12-14 2016-12-09 Glaxosmithkline Biologicals Sa Composicion antigenica de micobacteria.
FR2971509B1 (fr) * 2011-02-16 2013-02-22 Centre Nat Rech Scient Procede de preparation de peptides par assemblage de multiples fragments peptidiques
CN103290030A (zh) * 2012-02-23 2013-09-11 上海交通大学 一种结核分枝杆菌标志物HtdY的重组蛋白及其制备方法和临床应用
MX376235B (es) * 2012-05-04 2025-03-07 Pfizer Inc Antígenos asociados a próstata y regímenes de inmunoterapia basados en vacuna.
KR102643502B1 (ko) * 2014-04-04 2024-03-06 베스타론 코포레이션 인위적으로 활성화된 펩타이드
GB201513176D0 (en) 2015-07-27 2015-09-09 Glaxosmithkline Biolog Sa Novel methods for inducing an immune response
FR3048286B1 (fr) * 2016-02-26 2021-01-22 Omunis Peptides immunogenes et leur utilisation
CN107304231B (zh) * 2016-04-18 2021-01-01 华中农业大学 一种结核分枝杆菌融合蛋白及应用
GB201614485D0 (en) * 2016-08-25 2016-10-12 Univ Oxford Innovation Ltd Immunogenic composition

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Also Published As

Publication number Publication date
WO1997009428A2 (en) 1997-03-13
HUP9900902A3 (en) 2001-03-28
DE69630457D1 (de) 2003-11-27
WO1997009428A3 (en) 1997-07-17
CY2570B1 (en) 2008-07-02
KR100433750B1 (ko) 2004-09-01
AU7158696A (en) 1997-03-27
EP1347055A2 (en) 2003-09-24
CN1117149C (zh) 2003-08-06
CA2230885C (en) 2010-02-02
NO980883L (no) 1998-04-27
PT1347055E (pt) 2009-06-19
EP1203817B9 (en) 2006-08-16
JP4324597B2 (ja) 2009-09-02
DK1398379T3 (da) 2007-01-08
HU227778B1 (en) 2012-02-28
CZ300953B6 (cs) 2009-09-23
TR200901109T1 (tr) 2012-02-21
ES2262595T3 (es) 2006-12-01
CN1200147A (zh) 1998-11-25
EP1398379A3 (en) 2004-07-14
JP4324596B2 (ja) 2009-09-02
NZ319377A (en) 2000-01-28
EP1347055B1 (en) 2009-03-18
CA2230885A1 (en) 1997-03-13
DE69637879D1 (de) 2009-04-30
ATE337399T1 (de) 2006-09-15
BR9612997B1 (pt) 2012-01-10
NO20070618L (no) 1998-04-27
CZ297406B6 (cs) 2006-12-13
EP1203817A2 (en) 2002-05-08
JP2009159982A (ja) 2009-07-23
JP2006187292A (ja) 2006-07-20
HK1059282A1 (en) 2004-06-25
TR200403064T2 (tr) 2005-08-22
PT1398379E (pt) 2007-01-31
EP1712628A2 (en) 2006-10-18
JP2001517069A (ja) 2001-10-02
DE69636046D1 (de) 2006-05-24
DE69636487T2 (de) 2007-05-03
JP2007228972A (ja) 2007-09-13
PT851927E (pt) 2004-03-31
CZ62898A3 (cs) 1999-10-13
EP1203817A3 (en) 2003-01-29
BR9610262B1 (pt) 2013-11-26
IL123506A (en) 2004-12-15
NO324372B1 (no) 2007-10-01
NO980883D0 (no) 1998-02-27
ATE323165T1 (de) 2006-04-15
NO20070619L (no) 1998-04-27
AU727602B2 (en) 2000-12-14
CA2684425A1 (en) 1997-03-13
TR199800411T1 (xx) 1998-05-21
PL325373A1 (en) 1998-07-20
DK1203817T3 (da) 2006-08-14
CY2612B2 (en) 2010-12-22
DK1347055T3 (da) 2009-06-29
JP2006149406A (ja) 2006-06-15
JP4324618B2 (ja) 2009-09-02
NO20070621L (no) 1998-04-27
EP0851927B1 (en) 2003-10-22
ES2271449T3 (es) 2007-04-16
EP1712628A3 (en) 2007-05-23
IL123506A0 (en) 1998-10-30
PL186774B1 (pl) 2004-02-27
EP1712628B1 (en) 2011-06-22
TR200806258T2 (tr) 2008-10-21
EP1347055A3 (en) 2003-11-26
KR19990044347A (ko) 1999-06-25
BR9610262A (pt) 1999-07-06
SI0851927T1 (en) 2004-02-29
EP0851927A2 (en) 1998-07-08
CA2653566A1 (en) 1997-03-13
CA2653566C (en) 2013-06-25
EP1398379A2 (en) 2004-03-17
ATE513915T1 (de) 2011-07-15
CZ300688B6 (cs) 2009-07-15
EP1203817B1 (en) 2006-04-12
DE69636487D1 (de) 2006-10-05
ES2324529T3 (es) 2009-08-10
DE69636046T2 (de) 2006-11-23
TR200806259T2 (tr) 2008-10-21
ES2210392T3 (es) 2004-07-01
DK0851927T3 (da) 2004-01-26
JP4382160B2 (ja) 2009-12-09
ATE426025T1 (de) 2009-04-15
DE69630457T2 (de) 2004-11-25
NO336288B1 (no) 2015-07-13
HU225979B1 (en) 2008-02-28
EP1398379B1 (en) 2006-08-23
ATE252640T1 (de) 2003-11-15
MX9801638A (es) 1998-05-31
PT1203817E (pt) 2006-08-31

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Owner name: CORIXA CORPORATION, US

Free format text: FORMER OWNER(S): CORIXA CORPORATION, US

MM4A Lapse of definitive patent protection due to non-payment of fees