DE69636046D1 - Verbindungen und Verfahren zur Immuntherapie und Diagnose von Tuberkulose - Google Patents

Verbindungen und Verfahren zur Immuntherapie und Diagnose von Tuberkulose

Info

Publication number: DE69636046D1
Authority: DE; Germany
Prior art keywords: tuberculosis; compounds; diagnosis; methods; immunotherapy
Prior art date: 1995-09-01
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

DE69636046T

Other languages

English (en)

Other versions

DE69636046T2 (de

Inventor

Steven G Reed

Yasir A W Skeiky

David C Dillon

Antonio Campos-Neto

Raymond L Houghton

Thomas S Vedvick

Daniel R Twardzik

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Corixa Corp

Original Assignee

Corixa Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-09-01

Filing date

1996-08-30

Publication date

2006-05-24

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27541835&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69636046(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1996-08-30 Application filed by Corixa Corp filed Critical Corixa Corp

2006-05-24 Publication of DE69636046D1 publication Critical patent/DE69636046D1/de

2006-11-23 Application granted granted Critical

2006-11-23 Publication of DE69636046T2 publication Critical patent/DE69636046T2/de

2016-08-31 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Genetics & Genomics (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Medicinal Chemistry (AREA)
Biotechnology (AREA)
Wood Science & Technology (AREA)
Immunology (AREA)
Zoology (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Public Health (AREA)
Gastroenterology & Hepatology (AREA)
Biophysics (AREA)
Veterinary Medicine (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Animal Behavior & Ethology (AREA)
General Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Microbiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Pulmonology (AREA)
Epidemiology (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Physics & Mathematics (AREA)
Plant Pathology (AREA)
Cell Biology (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Peptides Or Proteins (AREA)
Saccharide Compounds (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

DE69636046T 1995-09-01 1996-08-30 Verbindungen und Verfahren zur Immuntherapie und Diagnose von Tuberkulose Expired - Lifetime DE69636046T2 (de)

Applications Claiming Priority (10)

Application Number	Priority Date	Filing Date
US620874		1984-06-15
US52343695A	1995-09-01	1995-09-01
US523436		1995-09-01
US53363495A	1995-09-22	1995-09-22
US533634		1995-09-22
US62087496A	1996-03-22	1996-03-22
US65968396A	1996-06-05	1996-06-05
US659683		1996-06-05
US68057496A	1996-07-12	1996-07-12
US680574		1996-07-12

Publications (2)

Publication Number	Publication Date
DE69636046D1 true DE69636046D1 (de)	2006-05-24
DE69636046T2 DE69636046T2 (de)	2006-11-23

Family

ID=27541835

Family Applications (4)

Application Number	Title	Priority Date	Filing Date
DE69636487T Expired - Lifetime DE69636487T2 (de)	1995-09-01	1996-08-30	Zusammensetzungen zur Immuntherapie und Diagnose von Tuberculosis
DE69630457T Expired - Lifetime DE69630457T2 (de)	1995-09-01	1996-08-30	Verbindungen zur immunotherapie und diagnose von tuberkulose
DE69636046T Expired - Lifetime DE69636046T2 (de)	1995-09-01	1996-08-30	Verbindungen und Verfahren zur Immuntherapie und Diagnose von Tuberkulose
DE69637879T Expired - Lifetime DE69637879D1 (de)	1995-09-01	1996-08-30	Verbindungen und Verfahren zur Immuntherapie und Diagnose von Tuberkulose

Family Applications Before (2)

Application Number	Title	Priority Date	Filing Date
DE69636487T Expired - Lifetime DE69636487T2 (de)	1995-09-01	1996-08-30	Zusammensetzungen zur Immuntherapie und Diagnose von Tuberculosis
DE69630457T Expired - Lifetime DE69630457T2 (de)	1995-09-01	1996-08-30	Verbindungen zur immunotherapie und diagnose von tuberkulose

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
DE69637879T Expired - Lifetime DE69637879D1 (de)	1995-09-01	1996-08-30	Verbindungen und Verfahren zur Immuntherapie und Diagnose von Tuberkulose

Country Status (24)

Country	Link
EP (5)	EP1203817B9 (de)
JP (5)	JP4382160B2 (de)
KR (1)	KR100433750B1 (de)
CN (1)	CN1117149C (de)
AT (5)	ATE323165T1 (de)
AU (1)	AU727602B2 (de)
BR (2)	BR9612997B1 (de)
CA (3)	CA2230885C (de)
CY (2)	CY2570B1 (de)
CZ (3)	CZ300953B6 (de)
DE (4)	DE69636487T2 (de)
DK (4)	DK1347055T3 (de)
ES (4)	ES2324529T3 (de)
HK (1)	HK1059282A1 (de)
HU (2)	HU225979B1 (de)
IL (1)	IL123506A (de)
MX (1)	MX9801638A (de)
NO (4)	NO324372B1 (de)
NZ (1)	NZ319377A (de)
PL (1)	PL186774B1 (de)
PT (4)	PT851927E (de)
SI (1)	SI0851927T1 (de)
TR (5)	TR200806258T2 (de)
WO (1)	WO1997009428A2 (de)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
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US6641814B1 (en)	1997-04-02	2003-11-04	Statens Serum Institut	Nucleic acids fragments and polypeptide fragments derived from M. tuberculosis
US6991797B2 (en)	1993-07-02	2006-01-31	Statens Serum Institut	M. tuberculosis antigens
US6290969B1 (en) *	1995-09-01	2001-09-18	Corixa Corporation	Compounds and methods for immunotherapy and diagnosis of tuberculosis
US6458366B1 (en)	1995-09-01	2002-10-01	Corixa Corporation	Compounds and methods for diagnosis of tuberculosis
US6592877B1 (en)	1995-09-01	2003-07-15	Corixa Corporation	Compounds and methods for immunotherapy and diagnosis of tuberculosis
TR199901569T2 (xx) *	1996-10-11	2000-12-21	Corixa Corporation	T�berk�lozun te�hisi i�in bile�ikler ve y�ntemler.
US6627198B2 (en)	1997-03-13	2003-09-30	Corixa Corporation	Fusion proteins of Mycobacterium tuberculosis antigens and their uses
US6544522B1 (en)	1998-12-30	2003-04-08	Corixa Corporation	Fusion proteins of mycobacterium tuberculosis antigens and their uses
US6350456B1 (en)	1997-03-13	2002-02-26	Corixa Corporation	Compositions and methods for the prevention and treatment of M. tuberculosis infection
US6982085B2 (en)	1997-04-02	2006-01-03	Statens Serum Institut	TB diagnostic based on antigens from M. tuberculosis
EP1449922B1 (de) *	1997-04-02	2007-08-15	Statens Serum Institut	Nukleinsäure- und Polypeptidfragmente von M. tuberculosis
US7037510B2 (en)	1997-04-18	2006-05-02	Statens Serum Institut	Hybrids of M. tuberculosis antigens
US6555653B2 (en)	1997-05-20	2003-04-29	Corixa Corporation	Compounds for diagnosis of tuberculosis and methods for their use
US6613881B1 (en) *	1997-05-20	2003-09-02	Corixa Corporation	Compounds for immunotherapy and diagnosis of tuberculosis and methods of their use
US7087713B2 (en)	2000-02-25	2006-08-08	Corixa Corporation	Compounds and methods for diagnosis and immunotherapy of tuberculosis
AU8123898A (en) *	1997-07-16	1999-02-10	Institut Pasteur	A polynucleotide functionally coding for the lhp protein from mycobacterium tuberculosis, its biologically active derivative fragments, as well as metho ds usingthe same
EP1029053A1 (de) *	1997-11-10	2000-08-23	Statens Seruminstitut	Nukleinsäurefragmente und polypeptide von mycobacterium tuberculosis
EP1484405A1 (de) *	1997-11-10	2004-12-08	Statens Serum Institut	Nukleinsäure- und polypeptidfragmente von M. Tuberculosis
HU228354B1 (en) *	1998-04-07	2013-03-28	Corixa Corp	Fusion proteins of mycobacterium tuberculosis antigens and their uses
GB9808720D0 (en) *	1998-04-23	1998-06-24	Smithkline Beecham Biolog	Novel compounds
CA2348475A1 (en) *	1998-11-04	2000-05-11	Isis Innovation Limited	Tuberculosis diagnostic test
US6465633B1 (en)	1998-12-24	2002-10-15	Corixa Corporation	Compositions and methods of their use in the treatment, prevention and diagnosis of tuberculosis
AU2594500A (en) *	1998-12-24	2000-07-31	Corixa Corporation	Methods for using mycobacterium tuberculosis molecules as immunological adjuvants
CA2372583C (en) *	1999-05-04	2012-07-10	The Public Health Research Institute Of The City Of New York, Inc.	Proteins expressed by mycobacterium tuberculosis and not by bcg and their use as diagnostic reagents and vaccines
US7009042B1 (en) *	1999-10-07	2006-03-07	Corixa Corporation	Methods of using a Mycobacterium tuberculosis coding sequence to facilitate stable and high yield expression of the heterologous proteins
US6316205B1 (en)	2000-01-28	2001-11-13	Genelabs Diagnostics Pte Ltd.	Assay devices and methods of analyte detection
EP1542732B1 (de)	2000-06-20	2009-09-16	Corixa Corporation	Fusionsproteine aus mycobakterium tuberculosis
AU2003213118A1 (en)	2002-02-15	2003-09-09	Corixa Corporation	Fusion proteins of mycobacterium tuberculosis
ITRM20040091A1 (it)	2004-02-19	2004-05-19	Istituto Naz Per Le Malattie	Test immunologico rapido per la diagnosi ed il monitoraggio dell'infezione tubercolare.
FI119445B (fi) *	2004-10-29	2008-11-14	Waertsilae Finland Oy	Polttomoottorin polttoaineen syöttöjärjestelmän paineen värähtelyn vaimennin
EA012037B1 (ru)	2004-11-16	2009-06-30	Круселл Холланд Б.В.	Поливалентные вакцины, содержащие рекомбинантные вирусные векторы
US8470338B2 (en)	2005-04-29	2013-06-25	Glaxosmithkline Biologicals, S.A.	Method for preventing or treating M tuberculosis infection
FR2952058B1 (fr) *	2009-10-29	2013-10-04	Centre Nat Rech Scient	Procede de ligation native de polypeptides
UA110103C2 (uk)	2010-01-27	2015-11-25	Ґлаксосмітклайн Байолоджікалз С.А.	Модифікований туберкульозний антиген
MX344280B (es)	2010-12-14	2016-12-09	Glaxosmithkline Biologicals Sa	Composicion antigenica de micobacteria.
FR2971509B1 (fr) *	2011-02-16	2013-02-22	Centre Nat Rech Scient	Procede de preparation de peptides par assemblage de multiples fragments peptidiques
CN103290030A (zh) *	2012-02-23	2013-09-11	上海交通大学	一种结核分枝杆菌标志物HtdY的重组蛋白及其制备方法和临床应用
MX376235B (es) *	2012-05-04	2025-03-07	Pfizer Inc	Antígenos asociados a próstata y regímenes de inmunoterapia basados en vacuna.
KR102643502B1 (ko) *	2014-04-04	2024-03-06	베스타론 코포레이션	인위적으로 활성화된 펩타이드
GB201513176D0 (en)	2015-07-27	2015-09-09	Glaxosmithkline Biolog Sa	Novel methods for inducing an immune response
FR3048286B1 (fr) *	2016-02-26	2021-01-22	Omunis	Peptides immunogenes et leur utilisation
CN107304231B (zh) *	2016-04-18	2021-01-01	华中农业大学	一种结核分枝杆菌融合蛋白及应用
GB201614485D0 (en) *	2016-08-25	2016-10-12	Univ Oxford Innovation Ltd	Immunogenic composition

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Publication number	Priority date	Publication date	Assignee	Title
FR2244539A1 (en) *	1973-07-13	1975-04-18	Mitsui Pharmaceuticals	Tuberculin active proteins and peptides prepn - from tubercle bacillus
FR2265402A1 (en) *	1974-03-29	1975-10-24	Mitsui Pharmaceuticals	Tuberculin active proteins and peptides prepn - from tubercle bacillus
US4876089A (en) *	1984-09-06	1989-10-24	Chiron Corporation	Feline leukemia virus protein vaccines
US4751180A (en)	1985-03-28	1988-06-14	Chiron Corporation	Expression using fused genes providing for protein product
US4935233A (en)	1985-12-02	1990-06-19	G. D. Searle And Company	Covalently linked polypeptide cell modulators
US5075109A (en)	1986-10-24	1991-12-24	Southern Research Institute	Method of potentiating an immune response
US4897268A (en)	1987-08-03	1990-01-30	Southern Research Institute	Drug delivery system and method of making the same
FR2677365B1 (fr) *	1991-06-07	1995-08-04	Pasteur Institut	Proteines de mycobacterium et applications.
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DK79793D0 (da) *	1993-07-02	1993-07-02	Statens Seruminstitut	Diagnostic test
DK79893D0 (da) *	1993-07-02	1993-07-02	Statens Seruminstitut	New vaccine

1996
- 1996-08-30 NZ NZ319377A patent/NZ319377A/xx not_active IP Right Cessation
- 1996-08-30 MX MX9801638A patent/MX9801638A/es not_active IP Right Cessation
- 1996-08-30 CA CA002230885A patent/CA2230885C/en not_active Expired - Fee Related
- 1996-08-30 DK DK03005931T patent/DK1347055T3/da active
- 1996-08-30 BR BRPI9612997-2A patent/BR9612997B1/pt not_active IP Right Cessation
- 1996-08-30 EP EP01126628A patent/EP1203817B9/de not_active Expired - Lifetime
- 1996-08-30 IL IL12350696A patent/IL123506A/en not_active IP Right Cessation
- 1996-08-30 CA CA002684425A patent/CA2684425A1/en not_active Abandoned
- 1996-08-30 PT PT96933009T patent/PT851927E/pt unknown
- 1996-08-30 CZ CZ20090166A patent/CZ300953B6/cs not_active IP Right Cessation
- 1996-08-30 HU HU9900902A patent/HU225979B1/hu not_active IP Right Cessation
- 1996-08-30 HU HU0900047A patent/HU227778B1/hu unknown
- 1996-08-30 PT PT03021501T patent/PT1398379E/pt unknown
- 1996-08-30 ES ES03005931T patent/ES2324529T3/es not_active Expired - Lifetime
- 1996-08-30 TR TR2008/06258T patent/TR200806258T2/xx unknown
- 1996-08-30 AT AT01126628T patent/ATE323165T1/de active
- 1996-08-30 JP JP51146497A patent/JP4382160B2/ja not_active Expired - Lifetime
- 1996-08-30 CA CA2653566A patent/CA2653566C/en not_active Expired - Lifetime
- 1996-08-30 ES ES96933009T patent/ES2210392T3/es not_active Expired - Lifetime
- 1996-08-30 AT AT06112509T patent/ATE513915T1/de not_active IP Right Cessation
- 1996-08-30 PT PT03005931T patent/PT1347055E/pt unknown
- 1996-08-30 EP EP03021501A patent/EP1398379B1/de not_active Expired - Lifetime
- 1996-08-30 TR TR1998/00411T patent/TR199800411T1/xx unknown
- 1996-08-30 DK DK01126628T patent/DK1203817T3/da active
- 1996-08-30 CZ CZ20060387A patent/CZ300688B6/cs not_active IP Right Cessation
- 1996-08-30 DE DE69636487T patent/DE69636487T2/de not_active Expired - Lifetime
- 1996-08-30 DK DK96933009T patent/DK0851927T3/da active
- 1996-08-30 WO PCT/US1996/014674 patent/WO1997009428A2/en active Application Filing
- 1996-08-30 DK DK03021501T patent/DK1398379T3/da active
- 1996-08-30 EP EP06112509A patent/EP1712628B1/de not_active Expired - Lifetime
- 1996-08-30 ES ES01126628T patent/ES2262595T3/es not_active Expired - Lifetime
- 1996-08-30 BR BRPI9610262-4B1A patent/BR9610262B1/pt not_active IP Right Cessation
- 1996-08-30 AU AU71586/96A patent/AU727602B2/en not_active Expired
- 1996-08-30 TR TR2009/01109T patent/TR200901109T1/xx unknown
- 1996-08-30 KR KR10-1998-0701589A patent/KR100433750B1/ko not_active IP Right Cessation
- 1996-08-30 EP EP96933009A patent/EP0851927B1/de not_active Revoked
- 1996-08-30 EP EP03005931A patent/EP1347055B1/de not_active Expired - Lifetime
- 1996-08-30 CZ CZ0062898A patent/CZ297406B6/cs not_active IP Right Cessation
- 1996-08-30 DE DE69630457T patent/DE69630457T2/de not_active Expired - Lifetime
- 1996-08-30 PT PT01126628T patent/PT1203817E/pt unknown
- 1996-08-30 TR TR2004/03064T patent/TR200403064T2/xx unknown
- 1996-08-30 AT AT96933009T patent/ATE252640T1/de not_active IP Right Cessation
- 1996-08-30 ES ES03021501T patent/ES2271449T3/es not_active Expired - Lifetime
- 1996-08-30 AT AT03005931T patent/ATE426025T1/de active
- 1996-08-30 PL PL96325373A patent/PL186774B1/pl not_active IP Right Cessation
- 1996-08-30 TR TR2008/06259T patent/TR200806259T2/xx unknown
- 1996-08-30 DE DE69636046T patent/DE69636046T2/de not_active Expired - Lifetime
- 1996-08-30 AT AT03021501T patent/ATE337399T1/de active
- 1996-08-30 SI SI9630644T patent/SI0851927T1/xx unknown
- 1996-08-30 CN CN96197639A patent/CN1117149C/zh not_active Expired - Lifetime
- 1996-08-30 DE DE69637879T patent/DE69637879D1/de not_active Expired - Lifetime
1998
- 1998-02-27 NO NO19980883A patent/NO324372B1/no not_active IP Right Cessation
2004
- 2004-03-08 HK HK04101684.5A patent/HK1059282A1/xx not_active IP Right Cessation
2006
- 2006-02-10 JP JP2006034592A patent/JP4324596B2/ja not_active Expired - Fee Related
- 2006-02-10 JP JP2006034593A patent/JP4324597B2/ja not_active Expired - Lifetime
- 2006-12-19 CY CY0600033A patent/CY2570B1/xx unknown
2007
- 2007-02-01 NO NO20070618A patent/NO336288B1/no not_active IP Right Cessation
- 2007-02-01 NO NO20070619A patent/NO20070619L/no not_active Application Discontinuation
- 2007-02-01 NO NO20070621A patent/NO20070621L/no not_active Application Discontinuation
- 2007-03-23 JP JP2007077972A patent/JP4324618B2/ja not_active Expired - Fee Related
2009
- 2009-04-08 JP JP2009094008A patent/JP2009159982A/ja not_active Ceased
- 2009-06-05 CY CY0900006A patent/CY2612B2/xx unknown

Also Published As

Publication number	Publication date
WO1997009428A2 (en)	1997-03-13
HUP9900902A3 (en)	2001-03-28
DE69630457D1 (de)	2003-11-27
WO1997009428A3 (en)	1997-07-17
CY2570B1 (en)	2008-07-02
KR100433750B1 (ko)	2004-09-01
AU7158696A (en)	1997-03-27
EP1347055A2 (de)	2003-09-24
CN1117149C (zh)	2003-08-06
CA2230885C (en)	2010-02-02
NO980883L (no)	1998-04-27
PT1347055E (pt)	2009-06-19
EP1203817B9 (de)	2006-08-16
JP4324597B2 (ja)	2009-09-02
DK1398379T3 (da)	2007-01-08
HU227778B1 (en)	2012-02-28
CZ300953B6 (cs)	2009-09-23
TR200901109T1 (tr)	2012-02-21
ES2262595T3 (es)	2006-12-01
CN1200147A (zh)	1998-11-25
EP1398379A3 (de)	2004-07-14
JP4324596B2 (ja)	2009-09-02
NZ319377A (en)	2000-01-28
EP1347055B1 (de)	2009-03-18
CA2230885A1 (en)	1997-03-13
DE69637879D1 (de)	2009-04-30
ATE337399T1 (de)	2006-09-15
BR9612997B1 (pt)	2012-01-10
NO20070618L (no)	1998-04-27
CZ297406B6 (cs)	2006-12-13
EP1203817A2 (de)	2002-05-08
JP2009159982A (ja)	2009-07-23
JP2006187292A (ja)	2006-07-20
HK1059282A1 (en)	2004-06-25
TR200403064T2 (tr)	2005-08-22
PT1398379E (pt)	2007-01-31
EP1712628A2 (de)	2006-10-18
JP2001517069A (ja)	2001-10-02
DE69636487T2 (de)	2007-05-03
JP2007228972A (ja)	2007-09-13
PT851927E (pt)	2004-03-31
CZ62898A3 (cs)	1999-10-13
EP1203817A3 (de)	2003-01-29
BR9610262B1 (pt)	2013-11-26
IL123506A (en)	2004-12-15
NO324372B1 (no)	2007-10-01
NO980883D0 (no)	1998-02-27
ATE323165T1 (de)	2006-04-15
NO20070619L (no)	1998-04-27
AU727602B2 (en)	2000-12-14
CA2684425A1 (en)	1997-03-13
TR199800411T1 (xx)	1998-05-21
PL325373A1 (en)	1998-07-20
DK1203817T3 (da)	2006-08-14
CY2612B2 (en)	2010-12-22
DK1347055T3 (da)	2009-06-29
JP2006149406A (ja)	2006-06-15
JP4324618B2 (ja)	2009-09-02
NO20070621L (no)	1998-04-27
EP0851927B1 (de)	2003-10-22
ES2271449T3 (es)	2007-04-16
EP1712628A3 (de)	2007-05-23
IL123506A0 (en)	1998-10-30
PL186774B1 (pl)	2004-02-27
EP1712628B1 (de)	2011-06-22
TR200806258T2 (tr)	2008-10-21
EP1347055A3 (de)	2003-11-26
HUP9900902A2 (hu)	1999-07-28
KR19990044347A (ko)	1999-06-25
BR9610262A (pt)	1999-07-06
SI0851927T1 (en)	2004-02-29
EP0851927A2 (de)	1998-07-08
CA2653566A1 (en)	1997-03-13
CA2653566C (en)	2013-06-25
EP1398379A2 (de)	2004-03-17
ATE513915T1 (de)	2011-07-15
CZ300688B6 (cs)	2009-07-15
EP1203817B1 (de)	2006-04-12
DE69636487D1 (de)	2006-10-05
ES2324529T3 (es)	2009-08-10
DE69636046T2 (de)	2006-11-23
TR200806259T2 (tr)	2008-10-21
ES2210392T3 (es)	2004-07-01
DK0851927T3 (da)	2004-01-26
JP4382160B2 (ja)	2009-12-09
ATE426025T1 (de)	2009-04-15
DE69630457T2 (de)	2004-11-25
NO336288B1 (no)	2015-07-13
HU225979B1 (en)	2008-02-28
EP1398379B1 (de)	2006-08-23
ATE252640T1 (de)	2003-11-15
MX9801638A (es)	1998-05-31
PT1203817E (pt)	2006-08-31

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ATE513915T1 (de)	2011-07-15	Verbindungen und verfahren zur immuntherapie und diagnose von tuberkulose
WO1998016646A3 (en)	1998-10-08	Compounds and methods for immunotherapy and diagnosis of tuberculosis
WO1998053075A3 (en)	1999-04-01	Compounds for immunotherapy and diagnosis of tuberculosis and methods of their use
WO1999042076A3 (en)	1999-10-14	Compounds and methods for immunotherapy and diagnosis of tuberculosis
CY1108864T1 (el)	2014-07-02	Ενωσεις για ανοσοθεραπεια και διαγνωση φυματιωσης και μεθοδοι χρησεις τους
AR010517A1 (es)	2000-06-28	Compuestos y metodos para la inmunoterapia y diagnostico de tuberculosis

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