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HUP9802394A2 - Szulfatált oligoszacharidok és ezeket hatóanyagként tartalmazó gyógyszerkészítmények - Google Patents

Szulfatált oligoszacharidok és ezeket hatóanyagként tartalmazó gyógyszerkészítmények

Info

Publication number
HUP9802394A2
HUP9802394A2 HU9802394A HUP9802394A HUP9802394A2 HU P9802394 A2 HUP9802394 A2 HU P9802394A2 HU 9802394 A HU9802394 A HU 9802394A HU P9802394 A HUP9802394 A HU P9802394A HU P9802394 A2 HUP9802394 A2 HU P9802394A2
Authority
HU
Hungary
Prior art keywords
monosaccharide
pharmaceutical compositions
active ingredients
compositions containing
sulfated oligosaccharides
Prior art date
Application number
HU9802394A
Other languages
English (en)
Inventor
William Butler Cowden
Christopher Richard Parish
Original Assignee
The Australian National University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=3786969&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUP9802394(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by The Australian National University filed Critical The Australian National University
Publication of HUP9802394A2 publication Critical patent/HUP9802394A2/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/702—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/722—Chitin, chitosan
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H11/00—Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/06—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0024—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof
    • C08B37/0027—2-Acetamido-2-deoxy-beta-glucans; Derivatives thereof
    • C08B37/003—Chitin, i.e. 2-acetamido-2-deoxy-(beta-1,4)-D-glucan or N-acetyl-beta-1,4-D-glucosamine; Chitosan, i.e. deacetylated product of chitin or (beta-1,4)-D-glucosamine; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Pulmonology (AREA)
  • Polymers & Plastics (AREA)
  • Materials Engineering (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Obesity (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Transplantation (AREA)
  • Ophthalmology & Optometry (AREA)
  • Emergency Medicine (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)

Abstract

A találmány tárgya szűlfatált őligőszacharid, ahől az őligőszacharid R1-(Rx)n-R2 (I) általánős képletű, a képletben R1 és R2, és mindegyik Rx jelentésemőnőszacharid egység, amelyek mindegyike azőnős vagy különböző lehet,a szőmszédős mőnőszacharid egységek12, 13, 14 és/vagy 16 glükőzidőskötéssel kapcsőlódnak egymáshőz, és n értéke 1, 2, 3, 4, 5 vagy 6. A találmány szerinti vegyületek angiőgenézisellenes, metasztázis-ellenes és gyűlladásellenes hatásúak. A találmány tárgyát képezik a fenti őligőszacharidőkat tartalmazó,angiőgenezisellenes, metasztázisellenes és gyűlladásellenes hatásúgyógyszerkészítmények is. ŕ
HU9802394A 1995-04-28 1996-04-24 Szulfatált oligoszacharidok és ezeket hatóanyagként tartalmazó gyógyszerkészítmények HUP9802394A2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AUPN2618A AUPN261895A0 (en) 1995-04-28 1995-04-28 Preparation and use of sulfated oligosaccharides

Publications (1)

Publication Number Publication Date
HUP9802394A2 true HUP9802394A2 (hu) 1999-02-01

Family

ID=3786969

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9802394A HUP9802394A2 (hu) 1995-04-28 1996-04-24 Szulfatált oligoszacharidok és ezeket hatóanyagként tartalmazó gyógyszerkészítmények

Country Status (26)

Country Link
US (1) US6143730A (hu)
EP (1) EP0837683B1 (hu)
JP (2) JP4514240B2 (hu)
KR (1) KR100591960B1 (hu)
CN (1) CN1090021C (hu)
AT (1) ATE463250T1 (hu)
AU (1) AUPN261895A0 (hu)
BR (1) BR9608041B8 (hu)
CA (1) CA2218872C (hu)
CZ (1) CZ341097A3 (hu)
DE (1) DE69638158D1 (hu)
EA (1) EA001199B1 (hu)
EE (1) EE9700277A (hu)
ES (1) ES2341924T3 (hu)
FI (1) FI974060L (hu)
HU (1) HUP9802394A2 (hu)
IL (1) IL118047A (hu)
IS (1) IS4596A (hu)
NO (1) NO974911L (hu)
NZ (1) NZ305815A (hu)
PL (1) PL184357B1 (hu)
PT (1) PT837683E (hu)
TR (1) TR199701264T1 (hu)
TW (1) TW446710B (hu)
WO (1) WO1996033726A1 (hu)
ZA (1) ZA963339B (hu)

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CN111904968A (zh) * 2020-08-21 2020-11-10 青岛市中心医院 硫酸半乳四糖及其衍生物在制备抗上皮细胞黏附药物中的应用
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EP0837683A4 (en) 2007-07-04
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EA199700347A1 (ru) 1998-06-25
CA2218872A1 (en) 1996-10-31
EE9700277A (et) 1998-04-15
FI974060A7 (fi) 1997-10-27
JP4514240B2 (ja) 2010-07-28
IL118047A0 (en) 1996-08-04
ATE463250T1 (de) 2010-04-15
IS4596A (is) 1997-10-21
KR100591960B1 (ko) 2007-12-04
TR199701264T1 (xx) 1998-02-21
AUPN261895A0 (en) 1995-05-18
NO974911D0 (no) 1997-10-24
IL118047A (en) 2000-11-21
JPH11504018A (ja) 1999-04-06
BR9608041B8 (pt) 2014-11-18
ES2341924T3 (es) 2010-06-29
US6143730A (en) 2000-11-07
EP0837683B1 (en) 2010-04-07
PT837683E (pt) 2010-07-09
CA2218872C (en) 2007-02-20
FI974060A0 (fi) 1997-10-27
FI974060L (fi) 1997-10-27
NO974911L (no) 1997-12-29
BR9608041A (pt) 1999-01-26
MX9708289A (es) 1998-06-30
CZ341097A3 (cs) 1998-03-18
ZA963339B (en) 1997-01-03
PL323080A1 (en) 1998-03-02
CN1090021C (zh) 2002-09-04
BR9608041B1 (pt) 2012-02-22
CN1183043A (zh) 1998-05-27
EP0837683A1 (en) 1998-04-29
KR19990008198A (ko) 1999-01-25
EA001199B1 (ru) 2000-12-25
WO1996033726A1 (en) 1996-10-31
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DE69638158D1 (de) 2010-05-20
PL184357B1 (pl) 2002-10-31

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