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HUP9801948A3 - Oxygenated-heterocycle containing sulfonamides and medicaments containing the same compounds - Google Patents

Oxygenated-heterocycle containing sulfonamides and medicaments containing the same compounds

Info

Publication number
HUP9801948A3
HUP9801948A3 HU9801948A HUP9801948A HUP9801948A3 HU P9801948 A3 HUP9801948 A3 HU P9801948A3 HU 9801948 A HU9801948 A HU 9801948A HU P9801948 A HUP9801948 A HU P9801948A HU P9801948 A3 HUP9801948 A3 HU P9801948A3
Authority
HU
Hungary
Prior art keywords
oxygenated
sulfonamides
same compounds
medicaments
heterocycle
Prior art date
Application number
HU9801948A
Other languages
English (en)
Hungarian (hu)
Original Assignee
Vertex Pharmaceuticals Inc Cam
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vertex Pharmaceuticals Inc Cam filed Critical Vertex Pharmaceuticals Inc Cam
Publication of HUP9801948A2 publication Critical patent/HUP9801948A2/hu
Publication of HUP9801948A3 publication Critical patent/HUP9801948A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/20—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
    • C07D317/24—Radicals substituted by singly bound oxygen or sulfur atoms esterified
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/32—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D317/34—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/32—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D317/34—Oxygen atoms
    • C07D317/36—Alkylene carbonates; Substituted alkylene carbonates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Furan Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
HU9801948A 1995-04-19 1996-04-18 Oxygenated-heterocycle containing sulfonamides and medicaments containing the same compounds HUP9801948A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/424,810 US5691372A (en) 1995-04-19 1995-04-19 Oxygenated-Heterocycle containing sulfonamide inhibitors of aspartyl protease

Publications (2)

Publication Number Publication Date
HUP9801948A2 HUP9801948A2 (hu) 1999-09-28
HUP9801948A3 true HUP9801948A3 (en) 2002-04-29

Family

ID=23683966

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9801948A HUP9801948A3 (en) 1995-04-19 1996-04-18 Oxygenated-heterocycle containing sulfonamides and medicaments containing the same compounds

Country Status (35)

Country Link
US (2) US5691372A (zh)
EP (3) EP0833826B1 (zh)
JP (1) JP4240532B2 (zh)
KR (1) KR100485237B1 (zh)
CN (1) CN1110491C (zh)
AP (2) AP9600827A0 (zh)
AR (1) AR004663A1 (zh)
AT (3) ATE314360T1 (zh)
AU (1) AU712913B2 (zh)
BG (1) BG102041A (zh)
BR (1) BR9608033A (zh)
CA (1) CA2217745C (zh)
CO (1) CO4700433A1 (zh)
CZ (1) CZ329497A3 (zh)
DE (3) DE69638252D1 (zh)
DK (1) DK0833826T3 (zh)
EA (1) EA000906B1 (zh)
EE (1) EE9700254A (zh)
ES (3) ES2256117T3 (zh)
GE (1) GEP20001915B (zh)
HK (2) HK1009811A1 (zh)
HU (1) HUP9801948A3 (zh)
IL (1) IL117962A0 (zh)
IS (1) IS4575A (zh)
MY (1) MY115797A (zh)
NO (1) NO974744D0 (zh)
NZ (1) NZ307342A (zh)
PE (1) PE43697A1 (zh)
PL (1) PL322904A1 (zh)
PT (1) PT833826E (zh)
SK (1) SK143097A3 (zh)
TR (1) TR199701194T1 (zh)
TW (1) TW404945B (zh)
WO (1) WO1996033187A1 (zh)
ZA (1) ZA962891B (zh)

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DE69321845T2 (de) 1992-08-25 1999-04-29 Monsanto Co Hydroxyethylaminosulfonamide verwendbar als inhibitoren retroviraler proteasen
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US20010049381A1 (en) 1997-06-04 2001-12-06 Gpl Nil Holdings, Inc., Pyrrolidine derivative hair growth compositions and uses
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WO1999065870A2 (en) 1998-06-19 1999-12-23 Vertex Pharmaceuticals Incorporated Sulfonamide inhibitors of aspartyl protease
JP4776775B2 (ja) * 1998-06-23 2011-09-21 アメリカ合衆国 Ｈｉｖ感染哺乳動物を治療するための医薬組成物
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US6395758B1 (en) 1998-08-14 2002-05-28 Gpi Nil Holdings, Inc. Small molecule carbamates or ureas for vision and memory disorders
US7338976B1 (en) 1998-08-14 2008-03-04 Gpi Nil Holdings, Inc. Heterocyclic esters or amides for vision and memory disorders
US6337340B1 (en) 1998-08-14 2002-01-08 Gpi Nil Holdings, Inc. Carboxylic acids and isosteres of heterocyclic ring compounds having multiple heteroatoms for vision and memory disorders
US6399648B1 (en) 1998-08-14 2002-06-04 Gpi Nil Holdings, Inc. N-oxides of heterocyclic ester, amide, thioester, or ketone for vision and memory disorders
US6218423B1 (en) 1998-08-14 2001-04-17 Gpi Nil Holdings, Inc. Pyrrolidine derivatives for vision and memory disorders
US6462072B1 (en) 1998-09-21 2002-10-08 Gpi Nil Holdings, Inc. Cyclic ester or amide derivatives
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Also Published As

Publication number Publication date
BG102041A (en) 1998-09-30
NO974744L (no) 1997-10-14
AU5665596A (en) 1996-11-07
AU712913B2 (en) 1999-11-18
IL117962A0 (en) 1996-08-04
PE43697A1 (es) 1997-10-11
EP1637528B1 (en) 2010-09-01
DE69618779T2 (de) 2002-08-29
BR9608033A (pt) 1999-01-12
AR004663A1 (es) 1999-03-10
ATE479674T1 (de) 2010-09-15
CN1110491C (zh) 2003-06-04
ATE314360T1 (de) 2006-01-15
EA199700330A1 (ru) 1998-04-30
EP1136479A1 (en) 2001-09-26
ES2256117T3 (es) 2006-07-16
CA2217745A1 (en) 1996-10-24
JPH11504628A (ja) 1999-04-27
US5691372A (en) 1997-11-25
AP9701104A0 (en) 1997-10-31
MY115797A (en) 2003-09-30
HK1009811A1 (en) 1999-06-11
GEP20001915B (en) 2000-01-05
WO1996033187A1 (en) 1996-10-24
HK1092791A1 (en) 2007-02-16
AP9600827A0 (en) 1997-10-17
DE69618779D1 (de) 2002-03-14
JP4240532B2 (ja) 2009-03-18
EP0833826A1 (en) 1998-04-08
EP1136479B1 (en) 2005-12-28
KR19990007823A (ko) 1999-01-25
EP0833826B1 (en) 2002-01-23
DE69638252D1 (de) 2010-10-14
DE69635679T2 (de) 2006-08-31
AP862A (en) 2000-08-04
CA2217745C (en) 2011-07-05
TW404945B (en) 2000-09-11
ATE212344T1 (de) 2002-02-15
EP1637528A1 (en) 2006-03-22
ES2351970T3 (es) 2011-02-14
DK0833826T3 (da) 2002-05-06
CZ329497A3 (cs) 1998-03-18
PL322904A1 (en) 1998-03-02
US5990155A (en) 1999-11-23
SK143097A3 (en) 1998-03-04
HUP9801948A2 (hu) 1999-09-28
PT833826E (pt) 2002-06-28
KR100485237B1 (ko) 2005-09-30
NZ307342A (en) 1999-04-29
EE9700254A (et) 1998-04-15
ES2171670T3 (es) 2002-09-16
TR199701194T1 (xx) 1998-03-21
EA000906B1 (ru) 2000-06-26
NO974744D0 (no) 1997-10-14
CN1184474A (zh) 1998-06-10
DE69635679D1 (de) 2006-02-02
IS4575A (is) 1997-10-02
ZA962891B (en) 1996-10-15
CO4700433A1 (es) 1998-12-29

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