NO974744D0 - Oksygenert-heterocykelinneholdende sulfonamidhemmere av aspartylprotease - Google Patents

Oksygenert-heterocykelinneholdende sulfonamidhemmere av aspartylprotease

Info

Publication number: NO974744D0
Authority: NO; Norway
Prior art keywords: heterocycle; oxygen; aspartyl protease; containing sulfonamide; sulfonamide inhibitors
Prior art date: 1995-04-19

Application number

NO974744A

Other languages

English (en)

Other versions

NO974744L (no

Inventor

Roger D Tung

Govinda Rao Bhisetti

Original Assignee

Vertex Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-04-19

Filing date

1997-10-14

Publication date

1997-10-14

1997-10-14 Application filed by Vertex Pharma filed Critical Vertex Pharma

1997-10-14 Publication of NO974744L publication Critical patent/NO974744L/no

1997-10-14 Publication of NO974744D0 publication Critical patent/NO974744D0/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/20—Oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
- C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
- C07D317/24—Radicals substituted by singly bound oxygen or sulfur atoms esterified
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/32—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D317/34—Oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/32—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D317/34—Oxygen atoms
- C07D317/36—Alkylene carbonates; Substituted alkylene carbonates
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
- C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Virology (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Molecular Biology (AREA)
Tropical Medicine & Parasitology (AREA)
AIDS & HIV (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
Furan Compounds (AREA)
Pyrane Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Peptides Or Proteins (AREA)
Enzymes And Modification Thereof (AREA)

NO974744A 1995-04-19 1997-10-14 Oksygenert-heterocykelinneholdende sulfonamidhemmere av aspartylprotease NO974744D0 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US08/424,810 US5691372A (en)	1995-04-19	1995-04-19	Oxygenated-Heterocycle containing sulfonamide inhibitors of aspartyl protease
PCT/US1996/005473 WO1996033187A1 (en)	1995-04-19	1996-04-18	Oxygenated-heterocycle containing sulfonamide inhibitors of aspartyl protease

Publications (2)

Publication Number	Publication Date
NO974744L NO974744L (no)	1997-10-14
NO974744D0 true NO974744D0 (no)	1997-10-14

Family

ID=23683966

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO974744A NO974744D0 (no)	1995-04-19	1997-10-14	Oksygenert-heterocykelinneholdende sulfonamidhemmere av aspartylprotease

Country Status (35)

Country	Link
US (2)	US5691372A (no)
EP (3)	EP0833826B1 (no)
JP (1)	JP4240532B2 (no)
KR (1)	KR100485237B1 (no)
CN (1)	CN1110491C (no)
AP (2)	AP9600827A0 (no)
AR (1)	AR004663A1 (no)
AT (3)	ATE212344T1 (no)
AU (1)	AU712913B2 (no)
BG (1)	BG102041A (no)
BR (1)	BR9608033A (no)
CA (1)	CA2217745C (no)
CO (1)	CO4700433A1 (no)
CZ (1)	CZ329497A3 (no)
DE (3)	DE69638252D1 (no)
DK (1)	DK0833826T3 (no)
EA (1)	EA000906B1 (no)
EE (1)	EE9700254A (no)
ES (3)	ES2351970T3 (no)
GE (1)	GEP20001915B (no)
HK (2)	HK1092791A1 (no)
HU (1)	HUP9801948A3 (no)
IL (1)	IL117962A0 (no)
IS (1)	IS4575A (no)
MY (1)	MY115797A (no)
NO (1)	NO974744D0 (no)
NZ (1)	NZ307342A (no)
PE (1)	PE43697A1 (no)
PL (1)	PL322904A1 (no)
PT (1)	PT833826E (no)
SK (1)	SK143097A3 (no)
TR (1)	TR199701194T1 (no)
TW (1)	TW404945B (no)
WO (1)	WO1996033187A1 (no)
ZA (1)	ZA962891B (no)

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CO5261510A1 (es)	1999-02-12	2003-03-31	Vertex Pharma	Inhibidores de aspartil proteasa
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AR031520A1 (es) *	1999-06-11	2003-09-24	Vertex Pharma	Un compuesto inhibidor de aspartilo proteasa, una composicion que lo comprende y un metodo para tratar un paciente con dicha composicion
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US7135465B2 (en)	2000-03-30	2006-11-14	Bristol-Myers Squibb Company	Sustained release beadlets containing stavudine
EA007383B1 (ru) *	2001-04-09	2006-10-27	Тиботек Фармасьютикалз Лтд.	2-(замещенный амино)бензоксазолсульфонамидные ингибиторы вич-протеазы широкого спектра
CA2472580A1 (en) *	2002-01-07	2003-07-17	Sequoia Pharmaceuticals	Broad spectrum inhibitors
US7157489B2 (en) *	2002-03-12	2007-01-02	The Board Of Trustees Of The University Of Illinois	HIV protease inhibitors
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1995
- 1995-04-19 US US08/424,810 patent/US5691372A/en not_active Expired - Lifetime
1996
- 1996-04-11 TW TW085104278A patent/TW404945B/zh not_active IP Right Cessation
- 1996-04-11 ZA ZA962891A patent/ZA962891B/xx unknown
- 1996-04-17 AR ARP960102210A patent/AR004663A1/es unknown
- 1996-04-17 AP APAP/P/1996/000827A patent/AP9600827A0/en unknown
- 1996-04-18 ES ES05028389T patent/ES2351970T3/es not_active Expired - Lifetime
- 1996-04-18 DE DE69638252T patent/DE69638252D1/de not_active Expired - Lifetime
- 1996-04-18 PL PL96322904A patent/PL322904A1/xx unknown
- 1996-04-18 CZ CZ973294A patent/CZ329497A3/cs unknown
- 1996-04-18 HU HU9801948A patent/HUP9801948A3/hu unknown
- 1996-04-18 EA EA199700330A patent/EA000906B1/ru not_active IP Right Cessation
- 1996-04-18 CN CN96193903A patent/CN1110491C/zh not_active Expired - Fee Related
- 1996-04-18 EE EE9700254A patent/EE9700254A/xx unknown
- 1996-04-18 EP EP96913811A patent/EP0833826B1/en not_active Expired - Lifetime
- 1996-04-18 TR TR97/01194T patent/TR199701194T1/xx unknown
- 1996-04-18 ES ES96913811T patent/ES2171670T3/es not_active Expired - Lifetime
- 1996-04-18 EP EP05028389A patent/EP1637528B1/en not_active Expired - Lifetime
- 1996-04-18 AT AT96913811T patent/ATE212344T1/de active
- 1996-04-18 EP EP01113575A patent/EP1136479B1/en not_active Expired - Lifetime
- 1996-04-18 DK DK96913811T patent/DK0833826T3/da active
- 1996-04-18 JP JP53195396A patent/JP4240532B2/ja not_active Expired - Lifetime
- 1996-04-18 IL IL11796296A patent/IL117962A0/xx unknown
- 1996-04-18 MY MYPI96001465A patent/MY115797A/en unknown
- 1996-04-18 GE GEAP19963972A patent/GEP20001915B/en unknown
- 1996-04-18 DE DE69618779T patent/DE69618779T2/de not_active Expired - Lifetime
- 1996-04-18 PE PE1996000266A patent/PE43697A1/es not_active Application Discontinuation
- 1996-04-18 CA CA2217745A patent/CA2217745C/en not_active Expired - Lifetime
- 1996-04-18 AU AU56655/96A patent/AU712913B2/en not_active Expired
- 1996-04-18 DE DE69635679T patent/DE69635679T2/de not_active Expired - Lifetime
- 1996-04-18 SK SK1430-97A patent/SK143097A3/sk unknown
- 1996-04-18 BR BR9608033A patent/BR9608033A/pt not_active Application Discontinuation
- 1996-04-18 ES ES01113575T patent/ES2256117T3/es not_active Expired - Lifetime
- 1996-04-18 WO PCT/US1996/005473 patent/WO1996033187A1/en active IP Right Grant
- 1996-04-18 PT PT96913811T patent/PT833826E/pt unknown
- 1996-04-18 AP APAP/P/1997/001104A patent/AP862A/en active
- 1996-04-18 AT AT01113575T patent/ATE314360T1/de active
- 1996-04-18 AT AT05028389T patent/ATE479674T1/de not_active IP Right Cessation
- 1996-04-18 KR KR1019970707346A patent/KR100485237B1/ko not_active IP Right Cessation
- 1996-04-19 CO CO96019067A patent/CO4700433A1/es unknown
1997
- 1997-10-02 IS IS4575A patent/IS4575A/is unknown
- 1997-10-08 NZ NZ307342A patent/NZ307342A/en unknown
- 1997-10-14 NO NO974744A patent/NO974744D0/no not_active Application Discontinuation
- 1997-11-13 BG BG102041A patent/BG102041A/xx unknown
- 1997-11-24 US US08/977,365 patent/US5990155A/en not_active Expired - Lifetime
1998
- 1998-09-22 HK HK06110563.0A patent/HK1092791A1/xx not_active IP Right Cessation
- 1998-09-22 HK HK98110833A patent/HK1009811A1/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
DE69638252D1 (de)	2010-10-14
AP9701104A0 (en)	1997-10-31
NO974744L (no)	1997-10-14
TR199701194T1 (xx)	1998-03-21
DE69635679D1 (de)	2006-02-02
MY115797A (en)	2003-09-30
EP0833826B1 (en)	2002-01-23
BG102041A (en)	1998-09-30
PL322904A1 (en)	1998-03-02
CO4700433A1 (es)	1998-12-29
EA199700330A1 (ru)	1998-04-30
HUP9801948A2 (hu)	1999-09-28
HK1092791A1 (en)	2007-02-16
ZA962891B (en)	1996-10-15
JP4240532B2 (ja)	2009-03-18
SK143097A3 (en)	1998-03-04
WO1996033187A1 (en)	1996-10-24
CZ329497A3 (cs)	1998-03-18
EP0833826A1 (en)	1998-04-08
ES2256117T3 (es)	2006-07-16
ATE314360T1 (de)	2006-01-15
HK1009811A1 (en)	1999-06-11
CN1184474A (zh)	1998-06-10
GEP20001915B (en)	2000-01-05
AU712913B2 (en)	1999-11-18
CA2217745C (en)	2011-07-05
EP1136479A1 (en)	2001-09-26
EP1637528B1 (en)	2010-09-01
ATE479674T1 (de)	2010-09-15
EE9700254A (et)	1998-04-15
CN1110491C (zh)	2003-06-04
PT833826E (pt)	2002-06-28
CA2217745A1 (en)	1996-10-24
AR004663A1 (es)	1999-03-10
AP9600827A0 (en)	1997-10-17
EP1136479B1 (en)	2005-12-28
NZ307342A (en)	1999-04-29
ES2351970T3 (es)	2011-02-14
EA000906B1 (ru)	2000-06-26
DK0833826T3 (da)	2002-05-06
AU5665596A (en)	1996-11-07
AP862A (en)	2000-08-04
KR19990007823A (ko)	1999-01-25
DE69618779D1 (de)	2002-03-14
KR100485237B1 (ko)	2005-09-30
PE43697A1 (es)	1997-10-11
BR9608033A (pt)	1999-01-12
IS4575A (is)	1997-10-02
JPH11504628A (ja)	1999-04-27
TW404945B (en)	2000-09-11
EP1637528A1 (en)	2006-03-22
US5990155A (en)	1999-11-23
DE69635679T2 (de)	2006-08-31
ES2171670T3 (es)	2002-09-16
HUP9801948A3 (en)	2002-04-29
ATE212344T1 (de)	2002-02-15
IL117962A0 (en)	1996-08-04
US5691372A (en)	1997-11-25
DE69618779T2 (de)	2002-08-29

Publication	Publication Date	Title
NO974722D0 (no)	1997-10-13	THF-inneholdende sulfonamidhemmere av aspartylprotease
NO974744D0 (no)	1997-10-14	Oksygenert-heterocykelinneholdende sulfonamidhemmere av aspartylprotease
NO303444B1 (no)	1998-07-13	Sulfonamidinhibitorer av HIV-aspartylprotease
NO20003332D0 (no)	2000-06-26	Midisinforløper av aspartylproteaseinhibitorer
NL300339I2 (nl)	2009-11-02	Sulfonamidederivaten als progeneesmiddelen van aspartylproteaseremmers
AP2000002023A0 (en)	2000-12-31	Sulfonamide inhibitors of aspartyl protease
NO20016034L (no)	2002-01-18	Inhibitorer av aspartylprotease
DE69631100D1 (de)	2004-01-29	Ätzung von Nitridkristallen
SI0846110T1 (en)	2003-04-30	Thf-containing sulfonamide inhibitors of aspartyl protease
HK1042892A1 (en)	2002-08-30	Oxygenated-heterocycle containing sulfonamide inhibitors of aspartyl protease
BR9612344A (pt)	1999-07-13	Inibidores de proteases

Legal Events

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2003-01-20	FC2A	Withdrawal, rejection or dismissal of laid open patent application