HUP0400371A3 - Use of carbon monoxide for preparation of pharmaceutical composition available for improving survival or function of organ following transplantation - Google Patents
Use of carbon monoxide for preparation of pharmaceutical composition available for improving survival or function of organ following transplantationInfo
- Publication number
- HUP0400371A3 HUP0400371A3 HU0400371A HUP0400371A HUP0400371A3 HU P0400371 A3 HUP0400371 A3 HU P0400371A3 HU 0400371 A HU0400371 A HU 0400371A HU P0400371 A HUP0400371 A HU P0400371A HU P0400371 A3 HUP0400371 A3 HU P0400371A3
- Authority
- HU
- Hungary
- Prior art keywords
- preparation
- function
- pharmaceutical composition
- carbon monoxide
- following transplantation
- Prior art date
Links
- UGFAIRIUMAVXCW-UHFFFAOYSA-N Carbon monoxide Chemical compound [O+]#[C-] UGFAIRIUMAVXCW-UHFFFAOYSA-N 0.000 title 1
- 229910002091 carbon monoxide Inorganic materials 0.000 title 1
- 210000000056 organ Anatomy 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 230000004083 survival effect Effects 0.000 title 1
- 238000002054 transplantation Methods 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
- A01N1/12—Chemical aspects of preservation
- A01N1/122—Preservation or perfusion media
- A01N1/126—Physiologically active agents, e.g. antioxidants or nutrients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Zoology (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Environmental Sciences (AREA)
- Transplantation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Materials For Medical Uses (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US30028901P | 2001-06-21 | 2001-06-21 | |
US33434001P | 2001-11-29 | 2001-11-29 | |
US33797401P | 2001-12-07 | 2001-12-07 | |
PCT/US2002/019687 WO2003000114A2 (en) | 2001-06-21 | 2002-06-21 | Carbon monoxide improves outcomes in tissue and organ transplants and suppresses apoptosis |
Publications (2)
Publication Number | Publication Date |
---|---|
HUP0400371A2 HUP0400371A2 (hu) | 2004-08-30 |
HUP0400371A3 true HUP0400371A3 (en) | 2010-06-28 |
Family
ID=27404726
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0400371A HUP0400371A3 (en) | 2001-06-21 | 2002-06-21 | Use of carbon monoxide for preparation of pharmaceutical composition available for improving survival or function of organ following transplantation |
Country Status (25)
Country | Link |
---|---|
US (2) | US7238469B2 (hu) |
EP (2) | EP2033514A3 (hu) |
JP (1) | JP4521183B2 (hu) |
KR (1) | KR20040032115A (hu) |
CN (1) | CN100502650C (hu) |
AT (1) | ATE413883T1 (hu) |
AU (2) | AU2002318377B2 (hu) |
BG (1) | BG108492A (hu) |
BR (1) | BR0210599A (hu) |
CA (1) | CA2451266A1 (hu) |
CY (1) | CY1108798T1 (hu) |
CZ (1) | CZ20033448A3 (hu) |
DE (1) | DE60229848D1 (hu) |
DK (1) | DK1404811T3 (hu) |
ES (1) | ES2316583T3 (hu) |
HU (1) | HUP0400371A3 (hu) |
MX (1) | MXPA03012031A (hu) |
NO (1) | NO20035637L (hu) |
NZ (1) | NZ562962A (hu) |
PL (1) | PL367544A1 (hu) |
PT (1) | PT1404811E (hu) |
SG (1) | SG147305A1 (hu) |
SI (1) | SI1404811T1 (hu) |
SK (1) | SK15942003A3 (hu) |
WO (1) | WO2003000114A2 (hu) |
Families Citing this family (41)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8128963B2 (en) | 1996-09-27 | 2012-03-06 | The Trustees Of Columbia University In The City Of New York | Methods for treating ischemic disorders using carbon monoxide |
US7678390B2 (en) | 1999-04-01 | 2010-03-16 | Yale University | Carbon monoxide as a biomarker and therapeutic agent |
GB0111872D0 (en) | 2001-05-15 | 2001-07-04 | Northwick Park Inst For Medica | Therapeutic agents and methods |
EP2033514A3 (en) | 2001-06-21 | 2009-04-29 | Beth Israel Deaconess Medical Center, Inc. | Carbon Monoxide Improves Outcomes in Cell and Organ Transplants and Suppresses Apoptosis |
NZ534912A (en) | 2002-02-04 | 2007-08-31 | Alfama Investigacao E Desenvol | supramolecule aggregate comprising CO containing organometallic or transition metal complex and anti-inflammatory agent or biphosphonate phosphonate derivative |
US20080026984A1 (en) * | 2002-02-04 | 2008-01-31 | Alfama - Investigacao E Desenvolvimento De Productos Farmaceuticos Lda | Methods for treating inflammatory disease by administering aldehydes and derivatives thereof |
US7968605B2 (en) * | 2002-02-04 | 2011-06-28 | ALFAMA—Investigação e Desenvolvimento de Produtos Farmacêuticos, Lda. | Methods for treating inflammatory disease by administering aldehydes and derivatives thereof |
SG148850A1 (en) | 2002-02-13 | 2009-01-29 | Beth Israel Hospital | Methods of treating vascular disease |
EP1499186A4 (en) | 2002-04-15 | 2009-10-28 | Beth Israel Hospital | USE OF HEME-OXYGENASE-1 AND HEME DEGRADATION PRODUCTS |
PL373002A1 (en) * | 2002-04-15 | 2005-08-08 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Methods of treating ileus |
MXPA04010242A (es) * | 2002-04-15 | 2005-06-08 | Univ Pittsburgh | Metodos para tratar enterocolitis necrotizante. |
DK1505990T3 (da) * | 2002-05-17 | 2011-11-21 | Univ Yale | Fremgangsmåder til behandling af hepatitis |
EA200401622A1 (ru) * | 2002-06-05 | 2005-06-30 | Йейл Юниверсити | Способы лечения ангиогенеза, роста опухолей и метастазов |
HRP20041204A2 (en) * | 2002-06-21 | 2005-06-30 | University Of Pittsburgh Of The Commonwealth Systebeth Israel Deaconess Medical Center | Pharmaceutical use of nitric oxide, heme oxygenase-1 and products of heme degradation |
CA2504604A1 (en) * | 2002-11-07 | 2004-05-27 | Timothy R. Billiar | Treatment for hemorrhagic shock |
GB2395432B (en) * | 2002-11-20 | 2005-09-14 | Northwick Park Inst For Medica | Therapeutic delivery of carbon monoxide to extracorporeal and isolated organs |
BRPI0415752A (pt) * | 2003-10-22 | 2006-12-19 | Hutchinson Fred Cancer Res | métodos, composições e dispositivos para indução de estase em células, tecidos, órgãos e organismos |
EP1552840A1 (en) * | 2004-01-07 | 2005-07-13 | Aga Ab | Use of a xenon/carbon monoxide mixture for the protection of cells |
EP1863503B1 (en) | 2005-03-07 | 2019-05-22 | Sangart, Inc. | Composition for delivering carbon monoxide (co) and nitric ozide (no) co to tissue using heme proteins as carriers |
US7977042B2 (en) * | 2005-07-27 | 2011-07-12 | University Of North Carolina At Charlotte | Composition and method for the restoration and preservation of transplant organs procured from DCD donors |
WO2007073226A1 (en) * | 2005-12-20 | 2007-06-28 | Alfama - Investigação E Desenvolvimento De Produtos Farmacêuticos Lda | Method for treating a mammal by administration of a compound having the ability to release co |
WO2007073225A1 (en) * | 2005-12-20 | 2007-06-28 | Alfama - Investigação E Desenvolvimento De Produtos Farmacêuticos Lda. | Molybdenum carbonyl complexes for treating rheumatoid arthritis and other inflammatory diseases |
GB0601394D0 (en) | 2006-01-24 | 2006-03-01 | Hemocorm Ltd | Therapeutic delivery of carbon monoxide |
KR20090087900A (ko) | 2006-11-07 | 2009-08-18 | 더 제너럴 하스피탈 코포레이션 | 혈관작용성 산소운반체에 의해 유도되는 혈관수축의 감소 |
EP2435121B1 (en) | 2009-05-27 | 2017-04-05 | INO Therapeutics LLC | Device for engaging an indexed valve and pressurized canister assembly with a collar |
AU2009202685B1 (en) | 2009-06-30 | 2010-08-19 | Ino Therapeutics Llc | Methods of treating term and near-term neonates having hypoxic respiratory failure associated with clinical or echocardiographic evidence of pulmonary hypertension |
CN103491783A (zh) | 2011-01-14 | 2014-01-01 | 洛杉矶儿童医院 | 用于治疗包括镰状细胞疾病的疾病的一氧化碳溶液 |
US8927750B2 (en) | 2011-02-04 | 2015-01-06 | Universitaet Zu Koeln | Acyloxy- and phosphoryloxy-butadiene-Fe(CO)3 complexes as enzyme-triggered co-releasing molecules |
CA2830420A1 (en) | 2011-03-16 | 2012-09-20 | Mayo Foundation For Medical Education And Research | Methods and materials for prolonging useful storage of red blood cell preparations and platelet preparations |
ES2656237T3 (es) | 2011-04-19 | 2018-02-26 | Alfama, Inc. | Moléculas liberadoras de monóxido de carbono y usos de las mismas |
JP2014520113A (ja) * | 2011-06-10 | 2014-08-21 | ゲノ エルエルシー | 一酸化窒素(no)の加圧容器 |
WO2013013179A1 (en) | 2011-07-21 | 2013-01-24 | Alfama, Inc. | Ruthenium carbon monoxide releasing molecules and uses thereof |
EP2741821A4 (en) | 2011-08-09 | 2015-10-07 | Beth Israel Hospital | METHOD FOR TREATING DNA DAMAGE |
ES2981406T3 (es) | 2013-03-15 | 2024-10-08 | Mallinckrodt Pharmaceuticals Ireland Ltd | Administración y monitorización de óxido nítrico en fluidos ex vivo |
US9629358B2 (en) | 2013-03-15 | 2017-04-25 | Mallinckrodt Hospital Products IP Limited | Administration and monitoring of nitric oxide in ex vivo fluids |
TW201618795A (zh) * | 2014-04-15 | 2016-06-01 | 波泰里斯股份有限公司 | 用以改良器官功能及延長器官移植物壽命之系統及方法 |
EP3334484B1 (en) | 2015-08-12 | 2024-12-25 | The General Hospital Corporation | Compositions that promote hypoxia or the hypoxia response for the treatment and prevention of mitochondrial dysfunction |
CN105288599A (zh) * | 2015-10-22 | 2016-02-03 | 徐州医学院 | 血红素氧化酶-2在制备抑制器官移植免疫排斥制剂中的应用 |
AU2018322317B2 (en) | 2017-08-25 | 2023-11-23 | Mallinckrodt Pharmaceuticals Ireland Limited | Methods to improve organ viability |
EP3524290A1 (en) | 2018-02-09 | 2019-08-14 | Julius-Maximilians-Universitaet Wuerzburg | Method and system for monitoring carbon monoxide (co) administration to ex-vivo fluids |
CN116076484A (zh) * | 2022-11-30 | 2023-05-09 | 武汉大学 | 一种修复肾脏损伤的低温携氧机械灌注液及其应用 |
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US8128963B2 (en) * | 1996-09-27 | 2012-03-06 | The Trustees Of Columbia University In The City Of New York | Methods for treating ischemic disorders using carbon monoxide |
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US6203991B1 (en) | 1998-08-21 | 2001-03-20 | The Regents Of The University Of Michigan | Inhibition of smooth muscle cell migration by heme oxygenase I |
US7678390B2 (en) * | 1999-04-01 | 2010-03-16 | Yale University | Carbon monoxide as a biomarker and therapeutic agent |
US20050250688A1 (en) | 1999-04-01 | 2005-11-10 | The Trustees Of Columbia University In The City Of New York | Methods for treating an ischemic disorder and improving stroke outcome |
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FR2816212A1 (fr) | 2000-11-03 | 2002-05-10 | Air Liquide Sante Int | Utilisation de monoxyde de carbone (co) dans le traitement des inflammations du systeme cardiovasculaire |
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EP1381354A2 (en) | 2001-03-30 | 2004-01-21 | Sangstat Medical Corporation | Carbon monoxide generating compounds for treatment of vascular, inflammatory and immune disorders |
GB0111872D0 (en) * | 2001-05-15 | 2001-07-04 | Northwick Park Inst For Medica | Therapeutic agents and methods |
EP1395241B9 (en) | 2001-05-25 | 2005-06-15 | Medtronic, Inc. | Implantable medical device with controllable gaseous agent release system |
EP2033514A3 (en) * | 2001-06-21 | 2009-04-29 | Beth Israel Deaconess Medical Center, Inc. | Carbon Monoxide Improves Outcomes in Cell and Organ Transplants and Suppresses Apoptosis |
NZ534912A (en) | 2002-02-04 | 2007-08-31 | Alfama Investigacao E Desenvol | supramolecule aggregate comprising CO containing organometallic or transition metal complex and anti-inflammatory agent or biphosphonate phosphonate derivative |
SG148850A1 (en) * | 2002-02-13 | 2009-01-29 | Beth Israel Hospital | Methods of treating vascular disease |
EP1499186A4 (en) * | 2002-04-15 | 2009-10-28 | Beth Israel Hospital | USE OF HEME-OXYGENASE-1 AND HEME DEGRADATION PRODUCTS |
MXPA04010242A (es) * | 2002-04-15 | 2005-06-08 | Univ Pittsburgh | Metodos para tratar enterocolitis necrotizante. |
PL373002A1 (en) * | 2002-04-15 | 2005-08-08 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Methods of treating ileus |
DK1505990T3 (da) * | 2002-05-17 | 2011-11-21 | Univ Yale | Fremgangsmåder til behandling af hepatitis |
EA200401622A1 (ru) * | 2002-06-05 | 2005-06-30 | Йейл Юниверсити | Способы лечения ангиогенеза, роста опухолей и метастазов |
HRP20041204A2 (en) * | 2002-06-21 | 2005-06-30 | University Of Pittsburgh Of The Commonwealth Systebeth Israel Deaconess Medical Center | Pharmaceutical use of nitric oxide, heme oxygenase-1 and products of heme degradation |
CA2504604A1 (en) * | 2002-11-07 | 2004-05-27 | Timothy R. Billiar | Treatment for hemorrhagic shock |
US20050255178A1 (en) * | 2004-02-04 | 2005-11-17 | Bloch Kenneth D | Enhancing the effectiveness of an inhaled therapeutic gas |
-
2002
- 2002-06-21 EP EP08168801A patent/EP2033514A3/en not_active Withdrawn
- 2002-06-21 WO PCT/US2002/019687 patent/WO2003000114A2/en active Application Filing
- 2002-06-21 DK DK02747932T patent/DK1404811T3/da active
- 2002-06-21 SK SK1594-2003A patent/SK15942003A3/sk not_active Application Discontinuation
- 2002-06-21 JP JP2003506568A patent/JP4521183B2/ja not_active Expired - Fee Related
- 2002-06-21 CA CA002451266A patent/CA2451266A1/en not_active Abandoned
- 2002-06-21 AU AU2002318377A patent/AU2002318377B2/en not_active Ceased
- 2002-06-21 PL PL02367544A patent/PL367544A1/xx unknown
- 2002-06-21 EP EP02747932A patent/EP1404811B1/en not_active Revoked
- 2002-06-21 SG SG200601852-7A patent/SG147305A1/en unknown
- 2002-06-21 ES ES02747932T patent/ES2316583T3/es not_active Expired - Lifetime
- 2002-06-21 DE DE60229848T patent/DE60229848D1/de not_active Expired - Lifetime
- 2002-06-21 BR BR0210599-3A patent/BR0210599A/pt not_active IP Right Cessation
- 2002-06-21 AT AT02747932T patent/ATE413883T1/de not_active IP Right Cessation
- 2002-06-21 NZ NZ562962A patent/NZ562962A/en not_active IP Right Cessation
- 2002-06-21 CZ CZ20033448A patent/CZ20033448A3/cs unknown
- 2002-06-21 PT PT02747932T patent/PT1404811E/pt unknown
- 2002-06-21 US US10/177,930 patent/US7238469B2/en not_active Expired - Lifetime
- 2002-06-21 CN CNB028163443A patent/CN100502650C/zh not_active Expired - Fee Related
- 2002-06-21 SI SI200230772T patent/SI1404811T1/sl unknown
- 2002-06-21 HU HU0400371A patent/HUP0400371A3/hu unknown
- 2002-06-21 KR KR10-2003-7016702A patent/KR20040032115A/ko not_active Abandoned
- 2002-06-21 MX MXPA03012031A patent/MXPA03012031A/es active IP Right Grant
-
2003
- 2003-12-17 NO NO20035637A patent/NO20035637L/no not_active Application Discontinuation
- 2003-12-22 BG BG108492A patent/BG108492A/xx unknown
-
2006
- 2006-04-10 US US11/401,722 patent/US20070202083A1/en not_active Abandoned
-
2008
- 2008-09-18 AU AU2008221551A patent/AU2008221551A1/en not_active Ceased
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2009
- 2009-02-09 CY CY20091100145T patent/CY1108798T1/el unknown
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