HUP0104027A3 - Stereoselective process for producing cryptophycin - Google Patents
Stereoselective process for producing cryptophycinInfo
- Publication number
- HUP0104027A3 HUP0104027A3 HU0104027A HUP0104027A HUP0104027A3 HU P0104027 A3 HUP0104027 A3 HU P0104027A3 HU 0104027 A HU0104027 A HU 0104027A HU P0104027 A HUP0104027 A HU P0104027A HU P0104027 A3 HUP0104027 A3 HU P0104027A3
- Authority
- HU
- Hungary
- Prior art keywords
- stereoselective process
- cryptophycin
- producing
- producing cryptophycin
- stereoselective
- Prior art date
Links
- 229930188224 Cryptophycin Natural products 0.000 title 1
- 108010006226 cryptophycin Proteins 0.000 title 1
- PSNOPSMXOBPNNV-VVCTWANISA-N cryptophycin 1 Chemical compound C1=C(Cl)C(OC)=CC=C1C[C@@H]1C(=O)NC[C@@H](C)C(=O)O[C@@H](CC(C)C)C(=O)O[C@H]([C@H](C)[C@@H]2[C@H](O2)C=2C=CC=CC=2)C/C=C/C(=O)N1 PSNOPSMXOBPNNV-VVCTWANISA-N 0.000 title 1
- PSNOPSMXOBPNNV-UHFFFAOYSA-N cryptophycin-327 Natural products C1=C(Cl)C(OC)=CC=C1CC1C(=O)NCC(C)C(=O)OC(CC(C)C)C(=O)OC(C(C)C2C(O2)C=2C=CC=CC=2)CC=CC(=O)N1 PSNOPSMXOBPNNV-UHFFFAOYSA-N 0.000 title 1
- 230000000707 stereoselective effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D273/00—Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D273/00—Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00
- C07D273/08—Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00 having two nitrogen atoms and more than one oxygen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Epoxy Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pyrane Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10466498P | 1998-10-16 | 1998-10-16 | |
| PCT/US1999/024410 WO2000023429A2 (en) | 1998-10-16 | 1999-10-15 | Stereoselective process for producing cryptophycins |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUP0104027A2 HUP0104027A2 (hu) | 2002-03-28 |
| HUP0104027A3 true HUP0104027A3 (en) | 2002-08-28 |
Family
ID=22301706
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0104027A HUP0104027A3 (en) | 1998-10-16 | 1999-10-15 | Stereoselective process for producing cryptophycin |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP1127055A2 (pt) |
| JP (1) | JP2002527509A (pt) |
| KR (1) | KR20010099699A (pt) |
| AU (1) | AU1123200A (pt) |
| BR (1) | BR9916051A (pt) |
| CA (1) | CA2347246A1 (pt) |
| HU (1) | HUP0104027A3 (pt) |
| IL (1) | IL142565A0 (pt) |
| TR (1) | TR200101084T2 (pt) |
| WO (1) | WO2000023429A2 (pt) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI1006780A2 (pt) * | 2009-04-01 | 2019-03-26 | Lek Pharmaceuticals D. D. | processo para preparar um composto, processo para a preparação de 3-amino-2, 2-dimetilpropanamida,processo para preparar um agente terapêutico, profilático ou de diagnóstico, processo para preparar alisquireno, processo para preparar um derivado de criptoficina,uso de um composto,uso de 3-amino-2,2-dimetilpropanamida e uso de agente terapêutico,profilático ou de diagnóstico. |
| FR2947269B1 (fr) | 2009-06-29 | 2013-01-18 | Sanofi Aventis | Nouveaux composes anticancereux |
| CN102140068B (zh) * | 2010-01-30 | 2015-03-11 | 浙江华海药业股份有限公司 | 阿利吉仑中间体3-氨基-2,2-二甲基丙酰胺的制备方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CZ278197A3 (cs) * | 1995-03-07 | 1998-12-16 | University Of Hawaii | Kryptofycinové sloučeniny, způsob jejich výroby a farmaceutické prostředky na jejich bázi |
| ATE201018T1 (de) * | 1996-02-27 | 2001-05-15 | Lilly Co Eli | Cryptophycinderivate und ihre verwendung als antimikrotubuli mittel |
| CA2264557A1 (en) * | 1996-09-06 | 1998-03-12 | Eli Lilly And Company | Process and novel intermediates |
| IL131205A0 (en) * | 1997-02-26 | 2001-01-28 | Lilly Co Eli | Process for preparing pharmaceutical compounds |
-
1999
- 1999-10-15 EP EP99955034A patent/EP1127055A2/en not_active Withdrawn
- 1999-10-15 IL IL14256599A patent/IL142565A0/xx unknown
- 1999-10-15 AU AU11232/00A patent/AU1123200A/en not_active Abandoned
- 1999-10-15 KR KR1020017004775A patent/KR20010099699A/ko not_active Withdrawn
- 1999-10-15 TR TR2001/01084T patent/TR200101084T2/xx unknown
- 1999-10-15 CA CA002347246A patent/CA2347246A1/en not_active Abandoned
- 1999-10-15 HU HU0104027A patent/HUP0104027A3/hu unknown
- 1999-10-15 BR BR9916051-0A patent/BR9916051A/pt not_active Application Discontinuation
- 1999-10-15 WO PCT/US1999/024410 patent/WO2000023429A2/en not_active Application Discontinuation
- 1999-10-15 JP JP2000577157A patent/JP2002527509A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| BR9916051A (pt) | 2001-08-14 |
| WO2000023429A3 (en) | 2000-07-27 |
| KR20010099699A (ko) | 2001-11-09 |
| HUP0104027A2 (hu) | 2002-03-28 |
| WO2000023429A2 (en) | 2000-04-27 |
| JP2002527509A (ja) | 2002-08-27 |
| EP1127055A2 (en) | 2001-08-29 |
| TR200101084T2 (tr) | 2001-09-21 |
| CA2347246A1 (en) | 2000-04-27 |
| AU1123200A (en) | 2000-05-08 |
| IL142565A0 (en) | 2002-03-10 |
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