HUE067383T2 - Fibronektin alapú, myostatinhoz kötõ állványdomén-fehérjék - Google Patents
Fibronektin alapú, myostatinhoz kötõ állványdomén-fehérjékInfo
- Publication number
- HUE067383T2 HUE067383T2 HUE20206702A HUE20206702A HUE067383T2 HU E067383 T2 HUE067383 T2 HU E067383T2 HU E20206702 A HUE20206702 A HU E20206702A HU E20206702 A HUE20206702 A HU E20206702A HU E067383 T2 HUE067383 T2 HU E067383T2
- Authority
- HU
- Hungary
- Prior art keywords
- myostatin
- bind
- domain proteins
- based scaffold
- scaffold domain
- Prior art date
Links
- 102100037362 Fibronectin Human genes 0.000 title 1
- 108010067306 Fibronectins Proteins 0.000 title 1
- 102100039939 Growth/differentiation factor 8 Human genes 0.000 title 1
- 108010056852 Myostatin Proteins 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
Classifications
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- C07K14/76—Albumins
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- C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
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- C07K14/79—Transferrins, e.g. lactoferrins, ovotransferrins
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- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
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- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/46—Hybrid immunoglobulins
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
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- C07K2319/00—Fusion polypeptide
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/31—Fusion polypeptide fusions, other than Fc, for prolonged plasma life, e.g. albumin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Biochemistry (AREA)
- Physical Education & Sports Medicine (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Hematology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Toxicology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Obesity (AREA)
- Rheumatology (AREA)
- Endocrinology (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Virology (AREA)
- Marine Sciences & Fisheries (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261700697P | 2012-09-13 | 2012-09-13 | |
US201361780005P | 2013-03-13 | 2013-03-13 |
Publications (1)
Publication Number | Publication Date |
---|---|
HUE067383T2 true HUE067383T2 (hu) | 2024-10-28 |
Family
ID=49253416
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HUE13767190A HUE043482T2 (hu) | 2012-09-13 | 2013-09-12 | Miosztatint megkötõ fibronektin alapú váz domén proteinek |
HUE19162848A HUE054699T2 (hu) | 2012-09-13 | 2013-09-12 | Miosztatinhoz kötõdõ fibronektinalapú vázdoménfehérjék |
HUE20206702A HUE067383T2 (hu) | 2012-09-13 | 2013-09-12 | Fibronektin alapú, myostatinhoz kötõ állványdomén-fehérjék |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HUE13767190A HUE043482T2 (hu) | 2012-09-13 | 2013-09-12 | Miosztatint megkötõ fibronektin alapú váz domén proteinek |
HUE19162848A HUE054699T2 (hu) | 2012-09-13 | 2013-09-12 | Miosztatinhoz kötõdõ fibronektinalapú vázdoménfehérjék |
Country Status (33)
Country | Link |
---|---|
US (9) | US8853154B2 (hu) |
EP (4) | EP3564258B1 (hu) |
JP (2) | JP6346895B2 (hu) |
KR (3) | KR102187714B1 (hu) |
CN (2) | CN108409856B (hu) |
AU (2) | AU2013315482B2 (hu) |
BR (1) | BR112015005466B1 (hu) |
CA (1) | CA2884730C (hu) |
CL (1) | CL2015000500A1 (hu) |
DK (3) | DK3835310T3 (hu) |
EA (1) | EA033536B1 (hu) |
ES (3) | ES2984405T3 (hu) |
FI (1) | FI3835310T3 (hu) |
HR (3) | HRP20240676T1 (hu) |
HU (3) | HUE043482T2 (hu) |
IL (3) | IL270110B (hu) |
LT (3) | LT3835310T (hu) |
MX (2) | MX366666B (hu) |
MY (2) | MY172863A (hu) |
NZ (2) | NZ628446A (hu) |
PE (1) | PE20150954A1 (hu) |
PH (1) | PH12015500397B1 (hu) |
PL (3) | PL3564258T3 (hu) |
PT (3) | PT2895503T (hu) |
RS (3) | RS65556B1 (hu) |
SG (3) | SG10201701970TA (hu) |
SI (3) | SI3564258T1 (hu) |
SM (1) | SMT202400214T1 (hu) |
TN (1) | TN2015000086A1 (hu) |
TW (2) | TWI633117B (hu) |
UY (2) | UY40128A (hu) |
WO (1) | WO2014043344A1 (hu) |
ZA (1) | ZA201501457B (hu) |
Families Citing this family (66)
Publication number | Priority date | Publication date | Assignee | Title |
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EP4001409A1 (en) | 2006-03-31 | 2022-05-25 | Chugai Seiyaku Kabushiki Kaisha | Methods for controlling blood pharmacokinetics of antibodies |
DK2202245T3 (en) | 2007-09-26 | 2016-11-21 | Chugai Pharmaceutical Co Ltd | A method of modifying an antibody isoelectric point VIA amino acid substitution in CDR |
JP4954326B2 (ja) | 2008-04-11 | 2012-06-13 | 中外製薬株式会社 | 複数分子の抗原に繰り返し結合する抗原結合分子 |
US9562089B2 (en) * | 2010-05-26 | 2017-02-07 | Bristol-Myers Squibb Company | Fibronectin based scaffold proteins having improved stability |
SG190727A1 (en) | 2010-11-30 | 2013-07-31 | Chugai Pharmaceutical Co Ltd | Antigen-binding molecule capable of binding to plurality of antigen molecules repeatedly |
DK2697257T3 (en) * | 2011-04-13 | 2017-01-30 | Bristol Myers Squibb Co | FC FUSION PROTEINS INCLUDING UNKNOWN LINKERS OR EVENTS |
SG11201500873XA (en) | 2012-08-24 | 2015-04-29 | Chugai Pharmaceutical Co Ltd | Fcgriib-specific fc region variant |
EP2889376A4 (en) | 2012-08-24 | 2016-11-02 | Chugai Pharmaceutical Co Ltd | ANTIBODIES Fc SPECIFIC TO FCTRII OF MOUSE |
HUE043482T2 (hu) | 2012-09-13 | 2019-08-28 | Bristol Myers Squibb Co | Miosztatint megkötõ fibronektin alapú váz domén proteinek |
MX362105B (es) | 2013-01-25 | 2019-01-04 | Shire Human Genetic Therapies | Folistatina en el tratamiento de distrofia muscular de duchenne. |
WO2014120891A2 (en) | 2013-02-01 | 2014-08-07 | Bristol-Myers Squibb Company | Fibronectin based scaffold proteins |
EP3406629B1 (en) | 2013-02-06 | 2020-06-24 | Bristol-Myers Squibb Company | Fibronectin type iii domain proteins with enhanced solubility |
WO2014126884A1 (en) | 2013-02-12 | 2014-08-21 | Bristol-Myers Squibb Company | High ph protein refolding methods |
CN113621057A (zh) | 2013-04-02 | 2021-11-09 | 中外制药株式会社 | Fc区变体 |
PT2981822T (pt) | 2013-05-06 | 2020-12-07 | Scholar Rock Inc | Composições e métodos para modulação do fator de crescimento |
IL275497B (en) | 2014-03-20 | 2022-09-01 | Bristol Myers Squibb Co | Serum albumin-binding fibronectin type iii domains |
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