HUE054594T2 - Bilasztint, béta-ciklodextrint és legalább egy gélesítõszert tartalmazó szemészeti kompozíciók - Google Patents

Bilasztint, béta-ciklodextrint és legalább egy gélesítõszert tartalmazó szemészeti kompozíciók

Info

Publication number: HUE054594T2
Authority: HU; Hungary
Prior art keywords: bilastine; cyclodextrin; beta; gelling agent; ophthalmic compositions
Prior art date: 2018-01-18

Application number

HUE19701154A

Other languages

English (en)

Inventor

Herrero Gonzalo Hernandez

Gorostiza Ana Gonzalo

Poladura Pablo Moran

Arce Arturo Zazpe

Hernando Nieves Fernandez

Garcia Tania Gonzalez

Cerdeiras Paloma Tato

Espinar Francisco Javier Otero

Ferreiro Anxo Fernandez

Tome Victoria Diaz

Original Assignee

Faes Farma Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2018-01-18

Filing date

2019-01-09

Publication date

2021-09-28

2019-01-09 Application filed by Faes Farma Sa filed Critical Faes Farma Sa

2021-09-28 Publication of HUE054594T2 publication Critical patent/HUE054594T2/hu

Links

229920000858 Cyclodextrin Polymers 0.000 title 1
239000001116 FEMA 4028 Substances 0.000 title 1
WHGYBXFWUBPSRW-FOUAGVGXSA-N beta-cyclodextrin Chemical compound OC[C@H]([C@H]([C@@H]([C@H]1O)O)O[C@H]2O[C@@H]([C@@H](O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O3)[C@H](O)[C@H]2O)CO)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@@H]3O[C@@H]1CO WHGYBXFWUBPSRW-FOUAGVGXSA-N 0.000 title 1
235000011175 beta-cyclodextrine Nutrition 0.000 title 1
229960004853 betadex Drugs 0.000 title 1
ACCMWZWAEFYUGZ-UHFFFAOYSA-N bilastine Chemical compound N=1C2=CC=CC=C2N(CCOCC)C=1C(CC1)CCN1CCC1=CC=C(C(C)(C)C(O)=O)C=C1 ACCMWZWAEFYUGZ-UHFFFAOYSA-N 0.000 title 1
229960004314 bilastine Drugs 0.000 title 1
239000003349 gelling agent Substances 0.000 title 1
239000000203 mixture Substances 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/40—Cyclodextrins; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Epidemiology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Ophthalmology & Optometry (AREA)
Oil, Petroleum & Natural Gas (AREA)
Inorganic Chemistry (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

HUE19701154A 2018-01-18 2019-01-09 Bilasztint, béta-ciklodextrint és legalább egy gélesítõszert tartalmazó szemészeti kompozíciók HUE054594T2 (hu)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP18382021		2018-01-18

Publications (1)

Publication Number	Publication Date
HUE054594T2 true HUE054594T2 (hu)	2021-09-28

Family

ID=61017875

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HUE19701154A HUE054594T2 (hu)	2018-01-18	2019-01-09	Bilasztint, béta-ciklodextrint és legalább egy gélesítõszert tartalmazó szemészeti kompozíciók

Country Status (28)

Country	Link
US (1)	US20210128544A1 (hu)
EP (2)	EP3915539A1 (hu)
JP (1)	JP7309729B2 (hu)
KR (1)	KR102695627B1 (hu)
CN (1)	CN111727035B (hu)
AR (1)	AR114216A1 (hu)
AU (1)	AU2019209214B2 (hu)
BR (1)	BR112020014265A2 (hu)
CA (1)	CA3088740A1 (hu)
CL (1)	CL2020001895A1 (hu)
CO (1)	CO2020009992A2 (hu)
CY (1)	CY1124270T1 (hu)
DK (1)	DK3740191T3 (hu)
EA (1)	EA202091725A1 (hu)
ES (1)	ES2878107T3 (hu)
HR (1)	HRP20211037T1 (hu)
HU (1)	HUE054594T2 (hu)
LT (1)	LT3740191T (hu)
MA (1)	MA51612B1 (hu)
MX (1)	MX2020007692A (hu)
PL (1)	PL3740191T3 (hu)
PT (1)	PT3740191T (hu)
SA (1)	SA520412443B1 (hu)
SI (1)	SI3740191T1 (hu)
TW (1)	TWI833727B (hu)
UY (1)	UY38055A (hu)
WO (1)	WO2019141563A1 (hu)
ZA (1)	ZA202005077B (hu)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU2023221541A1 (en)	2022-02-17	2024-08-08	Faes Farma, S.A.	Bilastine composition for once-daily parenteral administration
CN116211795A (zh) *	2022-12-26	2023-06-06	深圳市贝美药业有限公司	一种比拉斯汀口服液体制剂及其制备方法
CN115970066B (zh) *	2022-12-29	2024-09-27	成都爱睿康乐医疗器械有限公司	基于主客体相互作用的载药纳米凝胶生物润滑剂及其制备方法和应用
WO2024224308A1 (en) *	2023-04-27	2024-10-31	Leiutis Pharmaceuticals Llp	Liquid parenteral formulations of bilastine free of cyclodextrins
WO2024224326A1 (en) *	2023-04-27	2024-10-31	Leiutis Pharmaceuticals Llp	Liquid parenteral formulations of bilastine
WO2024256956A1 (en) *	2023-06-13	2024-12-19	Leiutis Pharmaceuticals Llp	Stable formulations of bilastine for nasal and ophthalmic use

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1229075B (it) *	1985-04-05	1991-07-17	Fidia Farmaceutici	Medicamenti per uso topico, ottenuti tramite l'impiego dell'acido ialuronico
ES2048109B1 (es)	1992-07-20	1994-12-16	Espanola Prod Quimicos	Procedimiento de preparacion de nuevos derivados piperidicos del bencimidazol.
JP3527256B2 (ja)	1992-12-09	2004-05-17	ロート製薬株式会社	抗アレルギー点眼剤
TW401300B (en) *	1992-12-25	2000-08-11	Senju Pharma Co	Antiallergic composition for ophthalmic or nasal use
ES2124167B1 (es)	1996-06-04	1999-09-16	Espanola Prod Quimicos	Nuevos derivados del bencimidazol con actividad antihistaminica.
DE10161149B4 (de)	2001-12-12	2007-03-08	Ursapharm Arzneimittel Gmbh & Co. Kg	Verwendung von Heparin-haltigem Ophthalmikum
DE60216641T2 (de)	2002-04-19	2007-09-27	Faes Farma S.A.	Polymorph von 4-ä2-ä4-ä1-(2-ethoxyethyl)-1h-benzimidazol-2-ylü-1-piperidinylüethylü-alpha, alpha-dimethylbenzolessigsäure
US20050239745A1 (en) *	2004-03-03	2005-10-27	Ophthalmic Research Associates, Inc.	Novel topical ophthalmic formulations
US7247623B2 (en)	2005-08-19	2007-07-24	Inspire Pharmaceuticals, Inc.	Method of treating dry eye disease with non-drying antihistamines
WO2007047253A2 (en)	2005-10-11	2007-04-26	Eastman Chemical Company	Pharmaceutical formulations of cyclodextrins and antifungal azole compounds
EP3150209B1 (en)	2006-03-31	2019-07-24	Vistakon Pharmaceuticals, LLC	Ocular allergy treatments
UA94938C2 (ru) *	2006-03-31	2011-06-25	ВИСТЕКОН ФАРМАСЬЮТИКАЛС, ЭлЭлСи	Офтальмическая композиция для лечения клинических симптомов глазной аллергии, которая содержит алкафтадин или его производное (варианты)
CN106038481A (zh)	2007-06-28	2016-10-26	锡德克斯药物公司	皮质类固醇水溶液的鼻部和眼部给药
EP2408302A4 (en)	2009-03-17	2012-08-15	Aciex Therapeutics Inc	OPHTALMIC FORMULATIONS OF KTOTICENE AND METHODS OF USE
TWI544922B (zh)	2011-05-19	2016-08-11	愛爾康研究有限公司	高濃度歐羅派特錠（ｏｌｏｐａｔａｄｉｎｅ）眼用組成物
CN103110575B (zh) *	2013-03-07	2014-11-05	宁夏康亚药业有限公司	一种美洛昔康滴眼液及其制备方法和应用
WO2014150899A1 (en)	2013-03-15	2014-09-25	Chapin Matthew J	Topical ophthalmic formulations for treating migraine
CN103784462A (zh) *	2014-02-25	2014-05-14	宋俊智	包含比拉斯汀及甾族化合物的药物制剂
EP3040334A1 (en)	2014-12-29	2016-07-06	Faes Farma, S.A.	New benzimidazole derivatives as antihistamine agents

2019
- 2019-01-09 CA CA3088740A patent/CA3088740A1/en not_active Abandoned
- 2019-01-09 SI SI201930076T patent/SI3740191T1/sl unknown
- 2019-01-09 MA MA51612A patent/MA51612B1/fr unknown
- 2019-01-09 EA EA202091725A patent/EA202091725A1/ru unknown
- 2019-01-09 PT PT197011547T patent/PT3740191T/pt unknown
- 2019-01-09 LT LTEP19701154.7T patent/LT3740191T/lt unknown
- 2019-01-09 CN CN201980009293.0A patent/CN111727035B/zh active Active
- 2019-01-09 EP EP21169956.6A patent/EP3915539A1/en not_active Withdrawn
- 2019-01-09 PL PL19701154T patent/PL3740191T3/pl unknown
- 2019-01-09 ES ES19701154T patent/ES2878107T3/es active Active
- 2019-01-09 AU AU2019209214A patent/AU2019209214B2/en active Active
- 2019-01-09 EP EP19701154.7A patent/EP3740191B1/en active Active
- 2019-01-09 BR BR112020014265-4A patent/BR112020014265A2/pt unknown
- 2019-01-09 WO PCT/EP2019/050433 patent/WO2019141563A1/en active Application Filing
- 2019-01-09 KR KR1020207023573A patent/KR102695627B1/ko active Active
- 2019-01-09 DK DK19701154.7T patent/DK3740191T3/da active
- 2019-01-09 MX MX2020007692A patent/MX2020007692A/es unknown
- 2019-01-09 HU HUE19701154A patent/HUE054594T2/hu unknown
- 2019-01-09 JP JP2020539288A patent/JP7309729B2/ja active Active
- 2019-01-09 US US16/963,219 patent/US20210128544A1/en active Pending
- 2019-01-17 TW TW108101861A patent/TWI833727B/zh active
- 2019-01-17 AR ARP190100094A patent/AR114216A1/es not_active Application Discontinuation
- 2019-01-18 UY UY38055A patent/UY38055A/es unknown
2020
- 2020-07-15 SA SA520412443A patent/SA520412443B1/ar unknown
- 2020-07-17 CL CL2020001895A patent/CL2020001895A1/es unknown
- 2020-08-13 CO CONC2020/0009992A patent/CO2020009992A2/es unknown
- 2020-08-17 ZA ZA2020/05077A patent/ZA202005077B/en unknown
2021
- 2021-06-25 CY CY20211100569T patent/CY1124270T1/el unknown
- 2021-06-30 HR HRP20211037TT patent/HRP20211037T1/hr unknown

Also Published As

Publication number	Publication date
KR102695627B1 (ko)	2024-08-16
LT3740191T (lt)	2021-08-10
TW201932110A (zh)	2019-08-16
AU2019209214A1 (en)	2020-08-13
CN111727035A (zh)	2020-09-29
CN111727035B (zh)	2024-05-28
ZA202005077B (en)	2024-12-18
DK3740191T3 (da)	2021-06-07
HRP20211037T1 (hr)	2021-10-01
SI3740191T1 (sl)	2021-09-30
KR20200111727A (ko)	2020-09-29
TWI833727B (zh)	2024-03-01
EP3915539A1 (en)	2021-12-01
ES2878107T3 (es)	2021-11-18
MX2020007692A (es)	2020-09-14
CY1124270T1 (el)	2022-07-22
AR114216A1 (es)	2020-08-05
EA202091725A1 (ru)	2020-10-12
MA51612A (fr)	2020-11-25
AU2019209214B2 (en)	2023-11-23
PL3740191T3 (pl)	2021-11-29
EP3740191B1 (en)	2021-04-28
MA51612B1 (fr)	2021-06-30
JP2021511317A (ja)	2021-05-06
CL2020001895A1 (es)	2020-12-04
WO2019141563A1 (en)	2019-07-25
CA3088740A1 (en)	2019-07-25
JP7309729B2 (ja)	2023-07-18
CO2020009992A2 (es)	2021-01-18
UY38055A (es)	2019-08-30
SA520412443B1 (ar)	2022-09-01
EP3740191A1 (en)	2020-11-25
US20210128544A1 (en)	2021-05-06
PT3740191T (pt)	2021-07-09
BR112020014265A2 (pt)	2020-12-08

Publication	Publication Date	Title
HUE054594T2 (hu)	2021-09-28	Bilasztint, béta-ciklodextrint és legalább egy gélesítõszert tartalmazó szemészeti kompozíciók
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