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HUE050665T2 - Radiojelzett MGLUR2/3 PET ligandumok - Google Patents

Radiojelzett MGLUR2/3 PET ligandumok

Info

Publication number
HUE050665T2
HUE050665T2 HUE16812961A HUE16812961A HUE050665T2 HU E050665 T2 HUE050665 T2 HU E050665T2 HU E16812961 A HUE16812961 A HU E16812961A HU E16812961 A HUE16812961 A HU E16812961A HU E050665 T2 HUE050665 T2 HU E050665T2
Authority
HU
Hungary
Prior art keywords
mglur2
radiolabeled
pet ligands
ligands
pet
Prior art date
Application number
HUE16812961A
Other languages
English (en)
Inventor
Jose Ignacio Andres-Gil
Gool Michiel Luc Maria Van
Guy Maurits R Bormans
Joost Verbeek
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of HUE050665T2 publication Critical patent/HUE050665T2/hu

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/041Heterocyclic compounds
    • A61K51/044Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K51/0459Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C07B59/002Heterocyclic compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HUE16812961A 2015-12-18 2016-12-16 Radiojelzett MGLUR2/3 PET ligandumok HUE050665T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP15201240 2015-12-18

Publications (1)

Publication Number Publication Date
HUE050665T2 true HUE050665T2 (hu) 2020-12-28

Family

ID=55023944

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE16812961A HUE050665T2 (hu) 2015-12-18 2016-12-16 Radiojelzett MGLUR2/3 PET ligandumok

Country Status (17)

Country Link
US (1) US11033641B2 (hu)
EP (1) EP3389727B1 (hu)
JP (1) JP6927974B2 (hu)
AU (1) AU2016374571B2 (hu)
CA (1) CA3003998A1 (hu)
CY (1) CY1124935T1 (hu)
DK (1) DK3389727T3 (hu)
ES (1) ES2828976T3 (hu)
HR (1) HRP20201372T1 (hu)
HU (1) HUE050665T2 (hu)
LT (1) LT3389727T (hu)
PL (1) PL3389727T3 (hu)
PT (1) PT3389727T (hu)
RS (1) RS60981B1 (hu)
SI (1) SI3389727T1 (hu)
SM (1) SMT202000591T1 (hu)
WO (1) WO2017103182A1 (hu)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
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JOP20150179B1 (ar) 2014-08-01 2021-08-17 Janssen Pharmaceutica Nv مركبات 6 ، 7 ثاني هيدرو بيرازولو [ 1، 5 الفا ] بيرازين – 4 (5 يد) – اون واستخدامها كمنظمات الوسترية سلبية لمستقبلات ملجور 2
EP3226915B1 (en) 2014-12-03 2019-02-20 Janssen Pharmaceutica NV Radiolabelled mglur2 pet ligands
AU2015357167B2 (en) 2014-12-03 2020-06-25 Janssen Pharmaceutica Nv 6,7-dihydropyrazolo(1,5-alpha)pyrazin-4(5H)-one compounds and their use as negative allosteric modulators of mGluR2 receptors
HUE050665T2 (hu) 2015-12-18 2020-12-28 Janssen Pharmaceutica Nv Radiojelzett MGLUR2/3 PET ligandumok
ES2820823T3 (es) * 2015-12-18 2021-04-22 Janssen Pharmaceutica Nv Ligandos PET mGluR2/3 radiomarcados
JP7242548B2 (ja) 2017-11-24 2023-03-20 住友ファーマ株式会社 6,7-ジヒドロピラゾロ[1,5-a]ピラジノン誘導体及びその医薬用途

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EP3226915B1 (en) 2014-12-03 2019-02-20 Janssen Pharmaceutica NV Radiolabelled mglur2 pet ligands
AU2015357167B2 (en) 2014-12-03 2020-06-25 Janssen Pharmaceutica Nv 6,7-dihydropyrazolo(1,5-alpha)pyrazin-4(5H)-one compounds and their use as negative allosteric modulators of mGluR2 receptors
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ES2820823T3 (es) * 2015-12-18 2021-04-22 Janssen Pharmaceutica Nv Ligandos PET mGluR2/3 radiomarcados
HUE050665T2 (hu) 2015-12-18 2020-12-28 Janssen Pharmaceutica Nv Radiojelzett MGLUR2/3 PET ligandumok

Also Published As

Publication number Publication date
EP3389727A1 (en) 2018-10-24
AU2016374571A1 (en) 2018-05-17
US11033641B2 (en) 2021-06-15
ES2828976T3 (es) 2021-05-28
SMT202000591T1 (it) 2020-11-10
PL3389727T3 (pl) 2021-02-08
WO2017103182A1 (en) 2017-06-22
PT3389727T (pt) 2020-10-30
JP6927974B2 (ja) 2021-09-01
US20200306389A1 (en) 2020-10-01
LT3389727T (lt) 2020-10-12
CA3003998A1 (en) 2017-06-22
DK3389727T3 (da) 2020-11-02
CY1124935T1 (el) 2022-07-22
SI3389727T1 (sl) 2020-10-30
AU2016374571B2 (en) 2021-05-06
HRP20201372T1 (hr) 2020-11-27
EP3389727B1 (en) 2020-08-12
JP2019502700A (ja) 2019-01-31
RS60981B1 (sr) 2020-11-30

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