HUE035931T2 - N-[2,4-bis(1,1-dimetiletil)-5-hidroxipenil]-1,4-dihidro-4-oxokinolin-3-karboxamid gyógyszerészeti készítménye és annak alkalmazása - Google Patents
N-[2,4-bis(1,1-dimetiletil)-5-hidroxipenil]-1,4-dihidro-4-oxokinolin-3-karboxamid gyógyszerészeti készítménye és annak alkalmazásaInfo
- Publication number
- HUE035931T2 HUE035931T2 HUE09789125A HUE09789125A HUE035931T2 HU E035931 T2 HUE035931 T2 HU E035931T2 HU E09789125 A HUE09789125 A HU E09789125A HU E09789125 A HUE09789125 A HU E09789125A HU E035931 T2 HUE035931 T2 HU E035931T2
- Authority
- HU
- Hungary
- Prior art keywords
- hydroxypenyl
- oxoquinoline
- dimethylethyl
- carboxamide
- dihydro
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
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- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
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- A61K9/2004—Excipients; Inactive ingredients
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- A61K9/2022—Organic macromolecular compounds
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- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
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- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
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- Neurology (AREA)
- Biomedical Technology (AREA)
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- Neurosurgery (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Obesity (AREA)
- Rheumatology (AREA)
- Reproductive Health (AREA)
- Urology & Nephrology (AREA)
- Otolaryngology (AREA)
- Hospice & Palliative Care (AREA)
- Gastroenterology & Hepatology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
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Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US8870408P | 2008-08-13 | 2008-08-13 | |
US8880108P | 2008-08-14 | 2008-08-14 | |
US9009608P | 2008-08-19 | 2008-08-19 | |
US14616309P | 2009-01-21 | 2009-01-21 | |
US18152709P | 2009-05-27 | 2009-05-27 | |
US18334509P | 2009-06-02 | 2009-06-02 |
Publications (1)
Publication Number | Publication Date |
---|---|
HUE035931T2 true HUE035931T2 (hu) | 2018-06-28 |
Family
ID=41206223
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HUE17204189A HUE053357T2 (hu) | 2008-08-13 | 2009-08-13 | Gyógyszerészeti készítmény és annak beadásai |
HUE09789125A HUE035931T2 (hu) | 2008-08-13 | 2009-08-13 | N-[2,4-bis(1,1-dimetiletil)-5-hidroxipenil]-1,4-dihidro-4-oxokinolin-3-karboxamid gyógyszerészeti készítménye és annak alkalmazása |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HUE17204189A HUE053357T2 (hu) | 2008-08-13 | 2009-08-13 | Gyógyszerészeti készítmény és annak beadásai |
Country Status (28)
Country | Link |
---|---|
US (1) | US20120220625A1 (hu) |
EP (3) | EP3842037A1 (hu) |
JP (2) | JP5575768B2 (hu) |
KR (5) | KR20220057663A (hu) |
CN (1) | CN102231990B (hu) |
AU (2) | AU2009282419B2 (hu) |
BR (1) | BRPI0916877A2 (hu) |
CA (1) | CA2733908C (hu) |
CY (2) | CY1119945T1 (hu) |
DK (2) | DK2328618T3 (hu) |
EA (1) | EA021706B1 (hu) |
ES (2) | ES2660143T3 (hu) |
HK (2) | HK1161140A1 (hu) |
HR (2) | HRP20180328T1 (hu) |
HU (2) | HUE053357T2 (hu) |
IL (3) | IL211203A (hu) |
LT (2) | LT2328618T (hu) |
ME (1) | ME03019B (hu) |
MX (3) | MX373230B (hu) |
NO (1) | NO2328618T3 (hu) |
NZ (1) | NZ591535A (hu) |
PL (2) | PL3345625T3 (hu) |
PT (2) | PT3345625T (hu) |
RS (2) | RS56894B1 (hu) |
SI (2) | SI3345625T1 (hu) |
SM (2) | SMT202100077T1 (hu) |
WO (1) | WO2010019239A2 (hu) |
ZA (1) | ZA201101097B (hu) |
Families Citing this family (107)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20100074949A1 (en) | 2008-08-13 | 2010-03-25 | William Rowe | Pharmaceutical composition and administration thereof |
AU2004272599A1 (en) | 2003-09-06 | 2005-03-24 | Vertex Pharmaceuticals Incorporated | Modulators of ATP-binding cassette transporters |
US7977322B2 (en) | 2004-08-20 | 2011-07-12 | Vertex Pharmaceuticals Incorporated | Modulators of ATP-binding cassette transporters |
DK2502911T3 (en) | 2004-06-24 | 2017-06-06 | Vertex Pharma | Modulators of ATP-binding cassette transporters |
CA2618057A1 (en) | 2005-08-11 | 2007-02-22 | Vertex Pharmaceuticals Incorporated | Modulators of cystic fibrosis transmembrane conductance regulator |
SI2404919T1 (sl) | 2005-11-08 | 2013-12-31 | Vertex Pharmaceuticals Incorporated | Heterocikliäśna spojina uporabna kot modulator za prenaĺ alce z atp-vezavno kaseto |
LT1993360T (lt) | 2005-12-28 | 2017-06-12 | Vertex Pharmaceuticals Incorporated | N-[2,4-bis(1,1-dimetiletil)-5-hidroksifenil]-1,4-dihidro-4-oksochinolin-3-karboksamido kieta forma |
CN101395147B (zh) | 2005-12-28 | 2013-05-29 | 弗特克斯药品有限公司 | 作为atp-结合盒转运蛋白调节剂用于治疗囊性纤维化的1-(苯并[d][1,3]间二氧杂环戊烯-5-基)-n-(苯基)环丙烷-甲酰胺衍生物及相关化合物 |
EP2007756B1 (en) | 2006-04-07 | 2015-08-26 | Vertex Pharmaceuticals Incorporated | Modulators of atp-binding cassette transporters |
US10022352B2 (en) | 2006-04-07 | 2018-07-17 | Vertex Pharmaceuticals Incorporated | Modulators of ATP-binding cassette transporters |
US7645789B2 (en) | 2006-04-07 | 2010-01-12 | Vertex Pharmaceuticals Incorporated | Indole derivatives as CFTR modulators |
US8563573B2 (en) | 2007-11-02 | 2013-10-22 | Vertex Pharmaceuticals Incorporated | Azaindole derivatives as CFTR modulators |
JP5497633B2 (ja) | 2007-05-09 | 2014-05-21 | バーテックス ファーマシューティカルズ インコーポレイテッド | Cftrのモジュレーター |
WO2009038913A2 (en) | 2007-08-24 | 2009-03-26 | Vertex Pharmaceuticals Incorporated | Isothiazolopyridinones useful for the treatment of (inter alia) cystic fibrosis |
DK2217572T3 (da) | 2007-11-16 | 2014-02-03 | Vertex Pharma | Isoquinoliner som modulatorer af ATP-bindingskassettetransportører |
ES2993060T3 (en) | 2007-12-07 | 2024-12-20 | Vertex Pharma | Solid forms of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyridin-2-yl) benzoic acid |
EP2237768A2 (en) * | 2007-12-07 | 2010-10-13 | Vertex Pharmaceuticals Incorporated | Formulations of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid |
PT2231606E (pt) | 2007-12-07 | 2013-05-17 | Vertex Pharma | Processos para a produção de ácidos cicloalquilcarboxiamido-piridina benzóicos |
US20100036130A1 (en) | 2007-12-07 | 2010-02-11 | Vertex Pharmaceuticals Incorporated | Processes for producing cycloalkylcarboxamido-pyridine benzoic acids |
CA2716109C (en) | 2008-02-28 | 2016-07-19 | Vertex Pharmaceuticals Incorporated | Heteroaryl derivatives as cftr modulators |
ES2442945T3 (es) | 2008-03-31 | 2014-02-14 | Vertex Pharmaceuticals Inc. | Derivados de piridilo como moduladores del CFTR |
AU2009296271A1 (en) * | 2008-09-29 | 2010-04-01 | Vertex Pharmaceuticals Incorporated | Dosage units of 3-(6-(1-(2,2-difluorobenzo [d] [1,3] dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid |
US8513282B2 (en) | 2008-10-23 | 2013-08-20 | Vertex Pharmaceuticals Incorporated | Modulators of cystic fibrosis transmembrane conductance regulator |
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