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HU176216B - Process for producing terminally bifuntional xylite derivatives of citostatic activity - Google Patents

Process for producing terminally bifuntional xylite derivatives of citostatic activity Download PDF

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Publication number
HU176216B
HU176216B HU78CI1826A HUCI001826A HU176216B HU 176216 B HU176216 B HU 176216B HU 78CI1826 A HU78CI1826 A HU 78CI1826A HU CI001826 A HUCI001826 A HU CI001826A HU 176216 B HU176216 B HU 176216B
Authority
HU
Hungary
Prior art keywords
preparation
formula
phenyl
dianhydroxyl
benzoyl
Prior art date
Application number
HU78CI1826A
Other languages
English (en)
Hungarian (hu)
Inventor
Laszlone Vidra
Laszlo Institoris
Sandor Eckhardt
Karoly Lapis
Andras Jeney
Laszlo Kopper
Original Assignee
Chinoin Gyogyszer Es Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer Es Vegyeszet filed Critical Chinoin Gyogyszer Es Vegyeszet
Priority to HU78CI1826A priority Critical patent/HU176216B/hu
Priority to IL57182A priority patent/IL57182A/xx
Priority to DE19792917538 priority patent/DE2917538A1/de
Priority to IN447/CAL/79A priority patent/IN150040B/en
Priority to EG264/79A priority patent/EG15150A/xx
Priority to GR59037A priority patent/GR68495B/el
Priority to FR7911733A priority patent/FR2425445A1/fr
Priority to FI791484A priority patent/FI67845C/fi
Priority to SE7904080A priority patent/SE7904080L/xx
Priority to YU01080/79A priority patent/YU108079A/xx
Priority to NL7903634A priority patent/NL7903634A/xx
Priority to CA000327317A priority patent/CA1145349A/en
Priority to AR276464A priority patent/AR222332A1/es
Priority to AT347779A priority patent/AT361945B/de
Priority to CH438979A priority patent/CH641437A5/de
Priority to NO791564A priority patent/NO153928C/no
Priority to GB7916274A priority patent/GB2024204B/en
Priority to BE0/195089A priority patent/BE876166A/xx
Priority to DK195279A priority patent/DK195279A/da
Priority to PL1979215489A priority patent/PL121560B1/pl
Priority to IT67984/79A priority patent/IT1118485B/it
Priority to CS793205A priority patent/CS211399B2/cs
Priority to JP5758879A priority patent/JPS5522662A/ja
Priority to SU792764801A priority patent/SU984410A3/ru
Priority to ES480869A priority patent/ES480869A1/es
Priority to DD79212780A priority patent/DD143765A5/de
Publication of HU176216B publication Critical patent/HU176216B/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/16—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by esterified hydroxyl radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/62—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/64—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by simultaneous introduction of -OH groups and halogens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/63—Esters of sulfonic acids
    • C07C309/64—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms
    • C07C309/65—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms of a saturated carbon skeleton
    • C07C309/66—Methanesulfonates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/63—Esters of sulfonic acids
    • C07C309/72—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C309/73—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton to carbon atoms of non-condensed six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C31/00—Saturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C31/34—Halogenated alcohols
    • C07C31/42—Polyhydroxylic acyclic alcohols
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/14—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by free hydroxyl radicals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Epoxy Compounds (AREA)
HU78CI1826A 1978-05-11 1978-05-11 Process for producing terminally bifuntional xylite derivatives of citostatic activity HU176216B (en)

Priority Applications (26)

Application Number Priority Date Filing Date Title
HU78CI1826A HU176216B (en) 1978-05-11 1978-05-11 Process for producing terminally bifuntional xylite derivatives of citostatic activity
IL57182A IL57182A (en) 1978-05-11 1979-04-30 Xylite derivatives,their preparation and cytostatic pharmaceutical compositions containing them
DE19792917538 DE2917538A1 (de) 1978-05-11 1979-04-30 Terminal-bifunktionelle xylit-derivate
IN447/CAL/79A IN150040B (de) 1978-05-11 1979-05-02
EG264/79A EG15150A (en) 1978-05-11 1979-05-06 Process for preparing of xylite derivatives as cell growing stimulants
GR59037A GR68495B (de) 1978-05-11 1979-05-07
FR7911733A FR2425445A1 (fr) 1978-05-11 1979-05-09 Derives de xylite bifonctionnels terminaux utiles comme medicaments
FI791484A FI67845C (fi) 1978-05-11 1979-05-09 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara xylitolderivat
SE7904080A SE7904080L (sv) 1978-05-11 1979-05-09 Terminal-bifunktionella xylitderivat
YU01080/79A YU108079A (en) 1978-05-11 1979-05-09 Process for producing terminal bifunctional xylitol derivatives
NL7903634A NL7903634A (nl) 1978-05-11 1979-05-09 Eindstandig-bifunctionale xyliet-derivaten.
CA000327317A CA1145349A (en) 1978-05-11 1979-05-10 Terminal bifunktional xylite-derivatives
AR276464A AR222332A1 (es) 1978-05-11 1979-05-10 Procedimiento para la produccion de derivados de la xilita
AT347779A AT361945B (de) 1978-05-11 1979-05-10 Verfahren zur herstellung von neuen xylit- -derivaten
CH438979A CH641437A5 (de) 1978-05-11 1979-05-10 Cytostatisch-wirkende xylit-derivate.
NO791564A NO153928C (no) 1978-05-11 1979-05-10 Analogifremgangsmaate ved fremstilling av xylit-derivater.
GB7916274A GB2024204B (en) 1978-05-11 1979-05-10 Cylitol derivatives their preparation and pharmaceutical compositions containing them
BE0/195089A BE876166A (fr) 1978-05-11 1979-05-10 Derives de xylite bifonctionnels terminaux utiles comme medicaments
DK195279A DK195279A (da) 1978-05-11 1979-05-10 Fremgangsmaade til fremstilling af xylitolderivater
PL1979215489A PL121560B1 (en) 1978-05-11 1979-05-10 Process for preparing novel derivatives of xylitol
IT67984/79A IT1118485B (it) 1978-05-11 1979-05-10 Derivati della xillite bifunzionali terminali
CS793205A CS211399B2 (en) 1978-05-11 1979-05-10 Method of making the the new xylite derivatives
JP5758879A JPS5522662A (en) 1978-05-11 1979-05-10 Enddgroup bifunctional xylite derivative
SU792764801A SU984410A3 (ru) 1978-05-11 1979-05-11 Способ получени производных 1,2-4,5-диангидроксилита
ES480869A ES480869A1 (es) 1978-05-11 1979-05-11 Procedimiento de preparar derivados de xilita.
DD79212780A DD143765A5 (de) 1978-05-11 1979-05-11 Verfahren zur herstellung von neuen xylit-derivaten

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU78CI1826A HU176216B (en) 1978-05-11 1978-05-11 Process for producing terminally bifuntional xylite derivatives of citostatic activity

Publications (1)

Publication Number Publication Date
HU176216B true HU176216B (en) 1981-01-28

Family

ID=10994695

Family Applications (1)

Application Number Title Priority Date Filing Date
HU78CI1826A HU176216B (en) 1978-05-11 1978-05-11 Process for producing terminally bifuntional xylite derivatives of citostatic activity

Country Status (26)

Country Link
JP (1) JPS5522662A (de)
AR (1) AR222332A1 (de)
AT (1) AT361945B (de)
BE (1) BE876166A (de)
CA (1) CA1145349A (de)
CH (1) CH641437A5 (de)
CS (1) CS211399B2 (de)
DD (1) DD143765A5 (de)
DE (1) DE2917538A1 (de)
DK (1) DK195279A (de)
EG (1) EG15150A (de)
ES (1) ES480869A1 (de)
FI (1) FI67845C (de)
FR (1) FR2425445A1 (de)
GB (1) GB2024204B (de)
GR (1) GR68495B (de)
HU (1) HU176216B (de)
IL (1) IL57182A (de)
IN (1) IN150040B (de)
IT (1) IT1118485B (de)
NL (1) NL7903634A (de)
NO (1) NO153928C (de)
PL (1) PL121560B1 (de)
SE (1) SE7904080L (de)
SU (1) SU984410A3 (de)
YU (1) YU108079A (de)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH381666A (de) * 1958-04-24 1964-09-15 Nat Res Dev Verfahren zur Herstellung von Derivaten von polyhydrischen Alkoholen
DE1668241A1 (de) * 1968-03-06 1971-02-11 Herbrand Kg Dr Therapeutisch wirksame 1,5-di-substituierte Derivate von Xylit,Adonit und Arabit

Also Published As

Publication number Publication date
GB2024204A (en) 1980-01-09
FI791484A (fi) 1979-11-12
FR2425445B1 (de) 1984-06-08
GR68495B (de) 1982-01-07
IL57182A0 (en) 1979-07-25
IT7967984A0 (it) 1979-05-10
CS211399B2 (en) 1982-02-26
IN150040B (de) 1982-07-03
CA1145349A (en) 1983-04-26
NO153928C (no) 1986-06-18
FI67845C (fi) 1985-06-10
SE7904080L (sv) 1979-11-12
DE2917538A1 (de) 1979-11-15
FR2425445A1 (fr) 1979-12-07
AR222332A1 (es) 1981-05-15
IT1118485B (it) 1986-03-03
SU984410A3 (ru) 1982-12-23
ES480869A1 (es) 1980-06-16
YU108079A (en) 1982-10-31
NO791564L (no) 1979-11-13
JPS5522662A (en) 1980-02-18
EG15150A (en) 1985-12-31
PL215489A1 (de) 1980-02-11
FI67845B (fi) 1985-02-28
PL121560B1 (en) 1982-05-31
GB2024204B (en) 1982-10-27
DD143765A5 (de) 1980-09-10
ATA347779A (de) 1980-09-15
DK195279A (da) 1979-11-12
BE876166A (fr) 1979-09-03
CH641437A5 (de) 1984-02-29
NL7903634A (nl) 1979-11-13
AT361945B (de) 1981-04-10
NO153928B (no) 1986-03-10
IL57182A (en) 1983-07-31

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