HRP20191069T1 - Stanice filamentoznih gljiva s deficijencijom o-manozil transferaze i postupci njihove uporabe - Google Patents
Stanice filamentoznih gljiva s deficijencijom o-manozil transferaze i postupci njihove uporabeInfo
- Publication number
- HRP20191069T1 HRP20191069T1 HRP20191069T HRP20191069T1 HR P20191069 T1 HRP20191069 T1 HR P20191069T1 HR P20191069 T HRP20191069 T HR P20191069T HR P20191069 T1 HRP20191069 T1 HR P20191069T1
- Authority
- HR
- Croatia
- Prior art keywords
- mannosyltransferase
- methods
- filamentous fungal
- fungal cells
- deficient filamentous
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1048—Glycosyltransferases (2.4)
- C12N9/1051—Hexosyltransferases (2.4.1)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y204/00—Glycosyltransferases (2.4)
- C12Y204/01—Hexosyltransferases (2.4.1)
- C12Y204/01109—Dolichyl-phosphate-mannose-protein mannosyltransferase (2.4.1.109)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
- C07K2317/41—Glycosylation, sialylation, or fucosylation
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Engineering & Computer Science (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Gastroenterology & Hepatology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP13175141 | 2013-07-04 | ||
| PCT/EP2014/064248 WO2015001049A1 (en) | 2013-07-04 | 2014-07-03 | O-mannosyltransferase deficient filamentous fungal cells and methods of use thereof |
| EP14734515.1A EP3016970B1 (en) | 2013-07-04 | 2014-07-03 | O-mannosyltransferase deficient filamentous fungal cells and methods of use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20191069T1 true HRP20191069T1 (hr) | 2019-11-01 |
Family
ID=48740957
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HRP20191069 HRP20191069T1 (hr) | 2013-07-04 | 2014-07-03 | Stanice filamentoznih gljiva s deficijencijom o-manozil transferaze i postupci njihove uporabe |
Country Status (15)
| Country | Link |
|---|---|
| US (4) | US20160376570A1 (hr) |
| EP (1) | EP3016970B1 (hr) |
| KR (1) | KR102111078B1 (hr) |
| CN (1) | CN105492457A (hr) |
| BR (1) | BR112015032695A2 (hr) |
| CA (1) | CA2916594C (hr) |
| DK (1) | DK3016970T3 (hr) |
| ES (1) | ES2739280T3 (hr) |
| HR (1) | HRP20191069T1 (hr) |
| MX (1) | MX364532B (hr) |
| PL (1) | PL3016970T3 (hr) |
| RU (1) | RU2016103373A (hr) |
| SG (1) | SG11201510814YA (hr) |
| SI (1) | SI3016970T1 (hr) |
| WO (1) | WO2015001049A1 (hr) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3172333B1 (en) | 2014-07-21 | 2020-05-13 | Glykos Finland Oy | Production of glycoproteins with mammalian-like n-glycans in filamentous fungi |
| CA3113661A1 (en) * | 2018-09-20 | 2020-03-26 | Perfect Day, Inc. | Methods and compositions for producing homokaryotic filamentous fungal cells |
| CA3121271A1 (en) * | 2018-11-28 | 2020-06-04 | Novozymes A/S | Modified filamentous fungal host cells |
| CN110885810B (zh) * | 2019-12-16 | 2021-03-23 | 华中农业大学 | 一种利用真核发酵制备得到的抑菌蛋白酶CmYC1及其应用 |
| CN115976033B (zh) * | 2022-12-14 | 2024-05-17 | 西南大学 | 瓜实蝇tssk1和tssk3基因及其应用 |
| KR20250004526A (ko) * | 2023-06-29 | 2025-01-08 | 씨제이제일제당 (주) | 아스파르트산 프로테아제 변이체 |
| CN119931997B (zh) * | 2025-04-09 | 2025-07-25 | 安琪酵母股份有限公司 | 天冬氨酸蛋白酶突变体及其应用 |
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| WO1998011203A1 (en) | 1996-09-13 | 1998-03-19 | Novo Nordisk Biotech, Inc. | Cells having dna insertion mutations which produce altered amounts of a polypeptide |
| DE19754622A1 (de) | 1997-12-09 | 1999-06-10 | Antje Von Dr Schaewen | Pflanzliche GntI-Sequenzen und Verwendung derselben zur Gewinnung von Pflanzen mit verminderter oder fehlender N-Acetylglucosaminyltransferase I (GnTI)-Aktivität |
| GB9902000D0 (en) | 1999-01-30 | 1999-03-17 | Delta Biotechnology Ltd | Process |
| GB0021421D0 (en) | 2000-08-31 | 2000-10-18 | Oxford Glycosciences Uk Ltd | Compounds |
| RU2003120093A (ru) | 2000-12-05 | 2005-01-27 | Дзе Пенн Стейт Рисерч Фаундейшн (Us) | Способы и композиции для высокоэффективного получения гетерологичных белков в дрожжах |
| EP1573017B1 (en) | 2002-12-20 | 2008-07-09 | Unilever Plc | Preparation of antifreeze protein |
| CA2513213C (en) | 2003-01-22 | 2013-07-30 | Human Genome Sciences, Inc. | Albumin fusion proteins |
| ZA200605449B (en) | 2003-12-03 | 2007-11-28 | Delta Biotechnology Ltd | Interleukin-11 fusion proteins |
| ES2567634T3 (es) | 2004-02-09 | 2016-04-25 | Human Genome Sciences, Inc. | Proteínas de fusión de albúmina |
| WO2006036817A2 (en) | 2004-09-24 | 2006-04-06 | Microbia, Inc. | Fungal variants and uses thereof |
| DK1941025T3 (da) * | 2005-10-17 | 2011-09-26 | Novozymes As | Brug af svampemutanter til ekspression af antistoffer |
| ES2534465T3 (es) | 2005-11-15 | 2015-04-23 | Glycofi, Inc. | Producción de glucoproteínas con O-glucosilación reducida |
| KR20090031359A (ko) | 2006-05-16 | 2009-03-25 | 교와 핫꼬 기린 가부시키가이샤 | 단백질의 고분비 생산 방법 |
| US8680252B2 (en) | 2006-12-10 | 2014-03-25 | Dyadic International (Usa), Inc. | Expression and high-throughput screening of complex expressed DNA libraries in filamentous fungi |
| GB0711424D0 (en) | 2007-06-13 | 2007-07-25 | Novozymes Delta Ltd | Recombinant transferrin mutants |
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| WO2009105357A1 (en) * | 2008-02-20 | 2009-08-27 | Glycofi, Inc. | Vectors and yeast strains for protein production |
| US20090253173A1 (en) * | 2008-04-08 | 2009-10-08 | Danisco Us Inc., Genencor Division | Filamentous fungi with inactivated protease genes for altered protein production |
| CA2721459A1 (en) | 2008-05-20 | 2009-11-26 | Merck Sharp & Dohme Corp. | Efficient production of heterologous proteins using mannosyl transferase inhibitors |
| JP2011530311A (ja) * | 2008-08-12 | 2011-12-22 | グライコフィ, インコーポレイテッド | タンパク質製造のための改良されたベクターおよび酵母株:Ca2+ATPアーゼ過剰発現 |
| WO2010034708A1 (en) | 2008-09-23 | 2010-04-01 | Unilever Plc | A polynucleotide expression cassette |
| KR101722961B1 (ko) | 2009-02-11 | 2017-04-04 | 알부메딕스 에이/에스 | 알부민 변이체 및 접합체 |
| EP2427488A1 (en) | 2009-05-07 | 2012-03-14 | Novozymes Biopharma DK A/S | Method of controlling o-linked glycosylation of antibodies |
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| KR20140018851A (ko) | 2010-11-24 | 2014-02-13 | 노파르티스 인터내셔널 파마슈티칼 리미티드 | N-아세틸글루코사미닐트랜스퍼라제 활성을 갖는 융합 효소 |
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-
2014
- 2014-07-03 ES ES14734515T patent/ES2739280T3/es active Active
- 2014-07-03 DK DK14734515.1T patent/DK3016970T3/da active
- 2014-07-03 WO PCT/EP2014/064248 patent/WO2015001049A1/en not_active Ceased
- 2014-07-03 HR HRP20191069 patent/HRP20191069T1/hr unknown
- 2014-07-03 CN CN201480048205.5A patent/CN105492457A/zh active Pending
- 2014-07-03 CA CA2916594A patent/CA2916594C/en active Active
- 2014-07-03 PL PL14734515T patent/PL3016970T3/pl unknown
- 2014-07-03 US US14/902,492 patent/US20160376570A1/en not_active Abandoned
- 2014-07-03 SI SI201431239T patent/SI3016970T1/sl unknown
- 2014-07-03 EP EP14734515.1A patent/EP3016970B1/en active Active
- 2014-07-03 MX MX2016000128A patent/MX364532B/es active IP Right Grant
- 2014-07-03 KR KR1020157036975A patent/KR102111078B1/ko active Active
- 2014-07-03 RU RU2016103373A patent/RU2016103373A/ru not_active Application Discontinuation
- 2014-07-03 BR BR112015032695A patent/BR112015032695A2/pt not_active Application Discontinuation
- 2014-07-03 SG SG11201510814YA patent/SG11201510814YA/en unknown
-
2018
- 2018-09-07 US US16/124,679 patent/US10724013B2/en active Active
-
2020
- 2020-06-15 US US16/901,175 patent/US20200362319A1/en not_active Abandoned
-
2022
- 2022-03-21 US US17/699,302 patent/US20220213451A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CN105492457A (zh) | 2016-04-13 |
| US20220213451A1 (en) | 2022-07-07 |
| CA2916594A1 (en) | 2015-01-08 |
| US10724013B2 (en) | 2020-07-28 |
| MX364532B (es) | 2019-04-29 |
| EP3016970A1 (en) | 2016-05-11 |
| DK3016970T3 (da) | 2019-06-24 |
| RU2016103373A3 (hr) | 2018-03-26 |
| KR20160030127A (ko) | 2016-03-16 |
| RU2016103373A (ru) | 2017-08-10 |
| SI3016970T1 (sl) | 2019-08-30 |
| KR102111078B1 (ko) | 2020-05-18 |
| SG11201510814YA (en) | 2016-01-28 |
| US20160376570A1 (en) | 2016-12-29 |
| WO2015001049A1 (en) | 2015-01-08 |
| CA2916594C (en) | 2020-03-10 |
| US20200362319A1 (en) | 2020-11-19 |
| PL3016970T3 (pl) | 2019-09-30 |
| ES2739280T3 (es) | 2020-01-30 |
| EP3016970B1 (en) | 2019-05-22 |
| MX2016000128A (es) | 2016-03-01 |
| US20200040314A1 (en) | 2020-02-06 |
| BR112015032695A2 (pt) | 2017-10-24 |
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