HRP20050756A2 - Process for the preparation of anticonvulsant derivatives of topiramate - Google Patents

Process for the preparation of anticonvulsant derivatives of topiramate

Info

Publication number: HRP20050756A2
Authority: HR; Croatia
Prior art keywords: preparation; topiramate; anticonvulsant derivatives; derivatives; anticonvulsant
Prior art date: 2003-03-04

Application number

HR20050756A

Other languages

English (en)

Croatian (hr)

Inventor

Ernest Barkner Joachim

Duncan Scott

Mills John

Original Assignee

Ortho-Mcneil Pharmaceutical

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-03-04

Filing date

2004-03-02

Publication date

2006-07-31

2004-03-02 Application filed by Ortho-Mcneil Pharmaceutical filed Critical Ortho-Mcneil Pharmaceutical

2006-07-31 Publication of HRP20050756A2 publication Critical patent/HRP20050756A2/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C307/00—Amides of sulfuric acids, i.e. compounds having singly-bound oxygen atoms of sulfate groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C307/02—Monoamides of sulfuric acids or esters thereof, e.g. sulfamic acids
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H9/00—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
- C07H9/02—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical the hetero ring containing only oxygen as ring hetero atoms
- C07H9/04—Cyclic acetals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A61P25/10—Antiepileptics; Anticonvulsants for petit-mal
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A61P25/12—Antiepileptics; Anticonvulsants for grand-mal
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C307/00—Amides of sulfuric acids, i.e. compounds having singly-bound oxygen atoms of sulfate groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C307/04—Diamides of sulfuric acids

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Neurosurgery (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biomedical Technology (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
Pain & Pain Management (AREA)
Neurology (AREA)
Veterinary Medicine (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Pyridine Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Saccharide Compounds (AREA)

HR20050756A 2003-03-04 2004-03-02 Process for the preparation of anticonvulsant derivatives of topiramate HRP20050756A2 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US45186303P	2003-03-04	2003-03-04
PCT/US2004/006263 WO2004078769A1 (en)	2003-03-04	2004-03-02	Process for the preparation of anticonvulsant derivatives of topiramate

Publications (1)

Publication Number	Publication Date
HRP20050756A2 true HRP20050756A2 (en)	2006-07-31

Family

ID=32962650

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HR20050756A HRP20050756A2 (en)	2003-03-04	2004-03-02	Process for the preparation of anticonvulsant derivatives of topiramate

Country Status (26)

Country	Link
US (1)	US7157589B2 (pt)
EP (1)	EP1599490B8 (pt)
JP (1)	JP4725976B2 (pt)
KR (1)	KR20050119111A (pt)
CN (1)	CN100376591C (pt)
AR (1)	AR043466A1 (pt)
AT (1)	ATE421521T1 (pt)
AU (1)	AU2004217974A1 (pt)
BR (1)	BRPI0407967A (pt)
CA (1)	CA2517964A1 (pt)
CL (1)	CL2004000438A1 (pt)
DE (1)	DE602004019191D1 (pt)
DK (1)	DK1599490T3 (pt)
ES (1)	ES2254047T3 (pt)
HR (1)	HRP20050756A2 (pt)
MX (1)	MXPA05009384A (pt)
MY (1)	MY139235A (pt)
NO (1)	NO20054538L (pt)
NZ (1)	NZ541811A (pt)
PT (1)	PT1599490E (pt)
RU (1)	RU2333216C2 (pt)
SI (1)	SI1599490T1 (pt)
TW (1)	TW200504089A (pt)
UA (1)	UA81657C2 (pt)
WO (1)	WO2004078769A1 (pt)
ZA (1)	ZA200507995B (pt)

Families Citing this family (57)

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US20060088886A1 (en) *	2004-10-25	2006-04-27	Anlong Ouyang	Topiramate analogs
US7638291B2 (en) *	2004-10-25	2009-12-29	Seradyn, Inc.	Immunoassays for topiramate
WO2007099388A1 (en) *	2006-03-01	2007-09-07	Glade Organics Private Limited	An improved process for the manufacture of topiramate
WO2008010231A2 (en) *	2006-05-26	2008-01-24	Alembic Limited	A process for the purification of topiramate
US20090076128A1 (en) *	2007-09-15	2009-03-19	Protia Llc	Deuterium-enriched topiramate
US9303038B2 (en)	2011-09-06	2016-04-05	Cellix Bio Private Limited	Compositions and methods for the treatment of epilepsy and neurological diseases
US9738631B2 (en)	2012-05-07	2017-08-22	Cellix Bio Private Limited	Compositions and methods for the treatment of neurological disorders
CN104603096A (zh)	2012-05-07	2015-05-06	塞利克斯比奥私人有限公司	用于治疗神经肌肉障碍和神经退行性疾病的组合物和方法
WO2013167990A1 (en)	2012-05-07	2013-11-14	Mahesh Kandula	Compositions and methods for the treatment of depression
WO2013168023A1 (en)	2012-05-08	2013-11-14	Mahesh Kandula	Compositions and methods for treatment of parkinson's disease
WO2013168025A1 (en)	2012-05-08	2013-11-14	Mahesh Kandula	Compositions and methods for treatment of blood clotting disorders
WO2013167992A1 (en)	2012-05-08	2013-11-14	Mahesh Kandula	Compositions and methods for the treatment of inflammatory disorders
WO2013167993A1 (en)	2012-05-08	2013-11-14	Mahesh Kandula	Compositions and methods for the treatment of neurological degenerative disorders
WO2013167991A1 (en)	2012-05-08	2013-11-14	Mahesh Kandula	Compositions and methods for the treatment of metabolic disorders
US9233161B2 (en)	2012-05-10	2016-01-12	Cellix Bio Private Limited	Compositions and methods for the treatment of neurological conditions
WO2013168000A1 (en)	2012-05-10	2013-11-14	Mahesh Kandula	Compositions and methods for the treatment of severe pain
US9339484B2 (en)	2012-05-10	2016-05-17	Cellix Bio Private Limited	Compositions and methods for the treatment of restless leg syndrome and fibromyalgia
US9346742B2 (en)	2012-05-10	2016-05-24	Cellix Bio Private Limited	Compositions and methods for the treatment of fibromyalgia pain
WO2013168033A1 (en)	2012-05-10	2013-11-14	Mahesh Kandula	Compositions and methods for treatment of neurologic diseases
US9394288B2 (en)	2012-05-10	2016-07-19	Cellix Bio Private Limited	Compositions and methods for the treatment of asthma and allergy
US9403857B2 (en)	2012-05-10	2016-08-02	Cellix Bio Private Limited	Compositions and methods for the treatment of metabolic syndrome
WO2013168001A1 (en)	2012-05-10	2013-11-14	Mahesh Kandula	Compositions and methods for the treatment of moderate to severe pain
WO2013167997A2 (en)	2012-05-10	2013-11-14	Mahesh Kandula	Compositions and methods for the treatment of metabolic syndrome
WO2013167999A2 (en)	2012-05-10	2013-11-14	Mahesh Kandula	Compositions and methods for the treatment of neurologic diseases
US9273061B2 (en)	2012-05-10	2016-03-01	Cellix Bio Private Limited	Compositions and methods for the treatment of chronic pain
US9242939B2 (en)	2012-05-10	2016-01-26	Cellix Bio Private Limited	Compositions and methods for the treatment of respiratory disorders
WO2013168014A1 (en)	2012-05-10	2013-11-14	Mahesh Kandula	Compositions and methods for the treatment of familial amyloid polyneuropathy
US9492409B2 (en)	2012-05-23	2016-11-15	Cellix Bio Private Limited	Compositions and methods for the treatment of local pain
WO2013175359A2 (en)	2012-05-23	2013-11-28	Mahesh Kandula	Compositions and methods for the treatment of multiple sclerosis
WO2013175347A2 (en)	2012-05-23	2013-11-28	Mahesh Kandula	Compositions and methods for the treatment of respiratory disorders
AU2013264820A1 (en)	2012-05-23	2014-11-27	Cellixbio Private Limited	Compositions and methods for treatment of mucositis
WO2013175344A2 (en)	2012-05-23	2013-11-28	Mahesh Kandula	Compositions and methods for the treatment of periodontitis and rheumatoid arthritis
SG11201407319YA (en)	2012-05-23	2014-12-30	Cellix Bio Private Ltd	Compositions and methods for treatment of inflammatory bowel disease
US9108942B1 (en)	2014-11-05	2015-08-18	Mahesh Kandula	Compositions and methods for the treatment of moderate to severe pain
US9187427B2 (en)	2012-08-03	2015-11-17	Cellix Bio Private Limited	N-substituted nicotinamide compounds and compositions for the treatment migraine and neurologic diseases
US9624168B2 (en)	2012-09-06	2017-04-18	Cellix Bio Private Limited	Compositions and methods for the treatment inflammation and lipid disorders
US9670153B2 (en)	2012-09-08	2017-06-06	Cellix Bio Private Limited	Compositions and methods for the treatment of inflammation and lipid disorders
US8652527B1 (en)	2013-03-13	2014-02-18	Upsher-Smith Laboratories, Inc	Extended-release topiramate capsules
US9101545B2 (en)	2013-03-15	2015-08-11	Upsher-Smith Laboratories, Inc.	Extended-release topiramate capsules
US9333187B1 (en)	2013-05-15	2016-05-10	Cellix Bio Private Limited	Compositions and methods for the treatment of inflammatory bowel disease
EP3004049B1 (en)	2013-06-04	2018-09-05	Cellixbio Private Limited	Compositions and methods for the treatment of diabetes and pre-diabetes
US9096537B1 (en)	2014-12-31	2015-08-04	Mahesh Kandula	Compositions and methods for the treatment of mucositis
CA2976314C (en)	2014-09-26	2021-02-23	Cellix Bio Private Limited	Compositions and methods for the treatment of epilepsy and neurological disorders
CA2967908C (en)	2014-09-29	2020-11-17	Mahesh Kandula	Compositions and methods for the treatment of multiple sclerosis
SG11201703369WA (en)	2014-10-27	2017-05-30	Cellix Bio Private Ltd	Three component salts of fumaric acid monomethyl ester with piperazine or ethylene diamine for the treatment of multiple sclerosis
US9284287B1 (en)	2014-11-05	2016-03-15	Cellix Bio Private Limited	Compositions and methods for the suppression of carbonic anhydrase activity
US9290486B1 (en)	2014-11-05	2016-03-22	Cellix Bio Private Limited	Compositions and methods for the treatment of epilepsy
US10208014B2 (en)	2014-11-05	2019-02-19	Cellix Bio Private Limited	Compositions and methods for the treatment of neurological disorders
US9175008B1 (en)	2014-11-05	2015-11-03	Cellix Bio Private Limited	Prodrugs of anti-platelet agents
US9321716B1 (en)	2014-11-05	2016-04-26	Cellix Bio Private Limited	Compositions and methods for the treatment of metabolic syndrome
US9150557B1 (en)	2014-11-05	2015-10-06	Cellix Bio Private Limited	Compositions and methods for the treatment of hyperglycemia
US9173877B1 (en)	2014-11-05	2015-11-03	Cellix Bio Private Limited	Compositions and methods for the treatment of local pain
US9932294B2 (en)	2014-12-01	2018-04-03	Cellix Bio Private Limited	Compositions and methods for the treatment of multiple sclerosis
US9206111B1 (en)	2014-12-17	2015-12-08	Cellix Bio Private Limited	Compositions and methods for the treatment of neurological diseases
SG11201705524SA (en)	2015-01-06	2017-08-30	Cellix Bio Private Ltd	Compositions and methods for the treatment of inflammation and pain
CN106632530A (zh) *	2016-12-08	2017-05-10	陕西大生制药科技有限公司	高纯度托吡酯的制备方法
CN108341844A (zh) *	2018-04-25	2018-07-31	广州小桔生物科技有限公司	一种高纯度托吡酯的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4513006A (en) *	1983-09-26	1985-04-23	Mcneil Lab., Inc.	Anticonvulsant sulfamate derivatives
US4582916A (en)	1983-09-26	1986-04-15	Mcneilab, Inc.	Chlorosulfate and azidosulfate esters of tetrahydro-2H-pyran-2-yl-methanol
AU651244B2 (en) *	1991-09-19	1994-07-14	Mcneilab, Inc.	Process for the preparation of chlorosulfate and sulfamate derivatives of 2,3:4,5-bis-0-(1-methylethylidene)-beta-D- fructopyranose and (1-methylcyclohexyl)methanol
FR2704226B1 (fr) *	1993-04-22	1995-07-21	Sanofi Elf	3-desoxy oligosaccharides, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
FR2751334B1 (fr) *	1996-07-19	1998-10-16	Sanofi Sa	Polysaccharides synthetiques, procede pour leur preparation et compositions pharmaceutiques les contenant

2004
- 2004-02-03 UA UAA200508358A patent/UA81657C2/ru unknown
- 2004-03-01 US US10/790,274 patent/US7157589B2/en not_active Expired - Lifetime
- 2004-03-02 CA CA002517964A patent/CA2517964A1/en not_active Abandoned
- 2004-03-02 DE DE602004019191T patent/DE602004019191D1/de not_active Expired - Lifetime
- 2004-03-02 HR HR20050756A patent/HRP20050756A2/xx not_active Application Discontinuation
- 2004-03-02 PT PT04716438T patent/PT1599490E/pt unknown
- 2004-03-02 CN CNB2004800057108A patent/CN100376591C/zh not_active Expired - Fee Related
- 2004-03-02 DK DK04716438T patent/DK1599490T3/da active
- 2004-03-02 MX MXPA05009384A patent/MXPA05009384A/es active IP Right Grant
- 2004-03-02 NZ NZ541811A patent/NZ541811A/en unknown
- 2004-03-02 JP JP2006508970A patent/JP4725976B2/ja not_active Expired - Fee Related
- 2004-03-02 KR KR1020057016420A patent/KR20050119111A/ko not_active Ceased
- 2004-03-02 AU AU2004217974A patent/AU2004217974A1/en not_active Abandoned
- 2004-03-02 AT AT04716438T patent/ATE421521T1/de not_active IP Right Cessation
- 2004-03-02 ES ES04716438T patent/ES2254047T3/es not_active Expired - Lifetime
- 2004-03-02 RU RU2005127626/04A patent/RU2333216C2/ru active
- 2004-03-02 EP EP04716438A patent/EP1599490B8/en not_active Expired - Lifetime
- 2004-03-02 SI SI200431098T patent/SI1599490T1/sl unknown
- 2004-03-02 WO PCT/US2004/006263 patent/WO2004078769A1/en active Application Filing
- 2004-03-02 BR BRPI0407967-1A patent/BRPI0407967A/pt not_active IP Right Cessation
- 2004-03-03 MY MYPI20040728A patent/MY139235A/en unknown
- 2004-03-03 TW TW093105458A patent/TW200504089A/zh unknown
- 2004-03-04 CL CL200400438A patent/CL2004000438A1/es unknown
- 2004-03-04 AR ARP040100680A patent/AR043466A1/es not_active Application Discontinuation
2005
- 2005-10-03 ZA ZA200507995A patent/ZA200507995B/en unknown
- 2005-10-03 NO NO20054538A patent/NO20054538L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
JP4725976B2 (ja)	2011-07-13
EP1599490B1 (en)	2009-01-21
ZA200507995B (en)	2007-01-31
BRPI0407967A (pt)	2006-03-07
SI1599490T1 (sl)	2009-06-30
CL2004000438A1 (es)	2005-01-21
KR20050119111A (ko)	2005-12-20
TW200504089A (en)	2005-02-01
US7157589B2 (en)	2007-01-02
JP2006519860A (ja)	2006-08-31
AR043466A1 (es)	2005-07-27
CA2517964A1 (en)	2004-09-16
US20040215004A1 (en)	2004-10-28
ES2254047T3 (es)	2009-05-14
WO2004078769A1 (en)	2004-09-16
HK1088336A1 (zh)	2006-11-03
EP1599490B8 (en)	2009-04-08
RU2333216C2 (ru)	2008-09-10
NO20054538L (no)	2005-10-03
ATE421521T1 (de)	2009-02-15
CN100376591C (zh)	2008-03-26
RU2005127626A (ru)	2006-01-27
EP1599490A1 (en)	2005-11-30
PT1599490E (pt)	2009-04-03
MY139235A (en)	2009-09-30
UA81657C2 (ru)	2008-01-25
MXPA05009384A (es)	2006-02-28
DE602004019191D1 (de)	2009-03-12
ES2254047T1 (es)	2006-06-16
DK1599490T3 (da)	2009-04-27
CN1756760A (zh)	2006-04-05
NZ541811A (en)	2008-07-31
AU2004217974A1 (en)	2004-09-16

Publication	Publication Date	Title
HRP20050756A2 (en)	2006-07-31	Process for the preparation of anticonvulsant derivatives of topiramate
WO2003097656A3 (en)	2004-06-10	Novel substituted sulfamate anticonvulsant derivatives
BR0309242A (pt)	2005-02-09	Derivados de acil-4-carboxifenil-uréia, processo para a sua preparação e sua aplicação
YU70901A (sh)	2005-07-19	Derivati 1,4-benzotiazepin-1,1 dioksida zamenjeni radikalima šećera, postupak za njihovu proizvodnju, lekovi koji sadrže ova jedinjenja i njihova primena
BR0215493A (pt)	2004-12-28	Processo para preparação de ésteres escopìnicos
BR0017030A (pt)	2003-01-07	Derivados de tiazolilamida
BR0214142A (pt)	2004-09-14	Derivados e intermediários de n-adamantilmetila como composições farmacêuticas e processos para sua preparação
BR0116067A (pt)	2003-10-28	Derivado de metanossulfonamido-benzofurano, seu processo de preparação e sua utilização como intermediário de sìntese
YU40997A (sh)	2000-10-30	Novi oksadiazoli, postupci za njihovo pripremanje
TNSN01047A1 (fr)	2005-11-10	Procede pour la preparation de derives de piperazine nouveaux
PT1259498E (pt)	2005-02-28	Derivados do 8,8a-di-hidroindeno[1,2-d]tiazole substituidos na posicao 8a, processo para a sua preparacao e sua utilizacao como medicamentos, p. ex. como anorecticos
BRPI0409716A (pt)	2006-05-02	derivados de 2-acilamino-4-feniltiazol, seu preparo e sua aplicação em terapêutica
PT1303632E (pt)	2005-02-28	Oligossacarideos de galactomanano e processo para a sua preparacao bem como sua utilizacao
EA200100983A1 (ru)	2002-10-31	Производные 13-метилэритромицина
BR9812895B1 (pt)	2009-05-05	derivados de triazolintiona, bem como processo para sua preparação.
BR0208534A (pt)	2004-03-23	Processo para preparação de 4,6-diaminopirimido[5,4-d]pirimidinas
DE60031886D1 (de)	2006-12-28	Purinderivate
MA28286A1 (fr)	2006-11-01	Dérivés de 1-N-phenyl-amino-1H-imidazole et compositions pharmaceutiques les contenant
BR0312593A (pt)	2005-04-12	Aciluréias substituìdas por uréia e uretano, processo para a sua produção e sua aplicação
BR0113259A (pt)	2003-07-15	Processo para a preparação de um composto, composto e processo para a preparação de compostos
UA66866C2 (uk)	2004-06-15	Синтез морфолінових похідних
YU37597A (en)	1999-11-22	New pyranosid derivatives
PT1206452E (pt)	2005-02-28	Processo de preparacao de compostos benzoper-hidroisoindole
HRP20050370A2 (en)	2006-07-31	Continuos process for the preparation of fructopyranose sulfamate derivatives
ATE446952T1 (de)	2009-11-15	Herstellungsverfahren von 2-cyanopyridinen

Legal Events

Date	Code	Title	Description
2006-07-31	A1OB	Publication of a patent application
2007-01-25	ARAI	Request for the grant of a patent on the basis of the submitted results of a substantive examination of a patent application
2009-03-02	ODRP	Renewal fee for the maintenance of a patent	Payment date: 20090302 Year of fee payment: 6
2010-02-04	OBST	Application withdrawn