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HRP20030324A2 - Compounds of antiinflammatory effect - Google Patents

Compounds of antiinflammatory effect Download PDF

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Publication number
HRP20030324A2
HRP20030324A2 HR20030324A HRP20030324A HRP20030324A2 HR P20030324 A2 HRP20030324 A2 HR P20030324A2 HR 20030324 A HR20030324 A HR 20030324A HR P20030324 A HRP20030324 A HR P20030324A HR P20030324 A2 HRP20030324 A2 HR P20030324A2
Authority
HR
Croatia
Prior art keywords
compounds
image
acid
compound
indicated
Prior art date
Application number
HR20030324A
Other languages
English (en)
Croatian (hr)
Inventor
Merep Mladen
Mesi Milan
Toma�kovi� Linda
Markovi� Stribor
Hrva�i� Bo�ka
Makaruha Oresta
Poljak Vi�nja
Original Assignee
Pliva-Istra�iva�ki institut d.o.o.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pliva-Istra�iva�ki institut d.o.o. filed Critical Pliva-Istra�iva�ki institut d.o.o.
Priority to HR20030324A priority Critical patent/HRP20030324A2/hr
Priority to US10/830,858 priority patent/US7579334B2/en
Priority to ES09075145T priority patent/ES2370371T3/es
Priority to YU20050873A priority patent/RS52621B/en
Priority to MEP-347/08A priority patent/MEP34708A/xx
Priority to RU2005131937/04A priority patent/RU2355699C2/ru
Priority to SI200431768T priority patent/SI2070940T1/sl
Priority to DK09075145.4T priority patent/DK2070940T3/da
Priority to BRPI0410490-0A priority patent/BRPI0410490A/pt
Priority to CNB2004800110487A priority patent/CN100393741C/zh
Priority to AU2004232546A priority patent/AU2004232546B2/en
Priority to HK06108841.8A priority patent/HK1086842B/zh
Priority to DK04729157T priority patent/DK1633771T3/da
Priority to SI200431253T priority patent/SI1633771T1/sl
Priority to JP2006506511A priority patent/JP4613366B2/ja
Priority to AT09075145T priority patent/ATE518876T1/de
Priority to KR1020057020252A priority patent/KR101107336B1/ko
Priority to DE602004022047T priority patent/DE602004022047D1/de
Priority to PT09075145T priority patent/PT2070940E/pt
Priority to CL200400872A priority patent/CL2004000872A1/es
Priority to HR20090551T priority patent/HRP20090551T1/hr
Priority to PL09075145T priority patent/PL2070940T3/pl
Priority to PL04729157T priority patent/PL1633771T3/pl
Priority to CA2523081A priority patent/CA2523081C/en
Priority to ES04729157T priority patent/ES2330109T3/es
Priority to MXPA05011359A priority patent/MXPA05011359A/es
Priority to EP09075145A priority patent/EP2070940B1/en
Priority to PCT/IB2004/001235 priority patent/WO2004094449A1/en
Priority to ARP040101400A priority patent/AR044083A1/es
Priority to PT04729157T priority patent/PT1633771E/pt
Priority to EP04729157A priority patent/EP1633771B1/en
Publication of HRP20030324A2 publication Critical patent/HRP20030324A2/hr
Priority to ZA200508388A priority patent/ZA200508388B/xx
Priority to IS8141A priority patent/IS2736B/is
Priority to NO20055535A priority patent/NO333909B1/no
Priority to HK09106861.4A priority patent/HK1129681B/zh
Priority to CY20091101070T priority patent/CY1109491T1/el
Priority to IS8941A priority patent/IS8941A/is
Priority to HR20110763T priority patent/HRP20110763T1/hr
Priority to CY20111101008T priority patent/CY1111978T1/el
Priority to NO20130898A priority patent/NO335552B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D273/00—Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Genetics & Genomics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Cardiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Neurosurgery (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
HR20030324A 2003-04-24 2003-04-24 Compounds of antiinflammatory effect HRP20030324A2 (en)

Priority Applications (40)

Application Number Priority Date Filing Date Title
HR20030324A HRP20030324A2 (en) 2003-04-24 2003-04-24 Compounds of antiinflammatory effect
US10/830,858 US7579334B2 (en) 2003-04-24 2004-04-22 Compounds with anti-inflammatory activity
CL200400872A CL2004000872A1 (es) 2003-04-24 2004-04-23 Compuestos derivados de m-l-d, donde m es la porcion aglicona de un macrolido, l es un grupo de enlace y d es una subunidad antiinflamatoria no esteroidal o una subunidad antiinflamatoria esteroidal; composicion farmaceutica, y uso para el tratamient
HR20090551T HRP20090551T1 (hr) 2003-04-24 2004-04-23 Makrolidni konjugati s protuupalnom aktivnošću
MEP-347/08A MEP34708A (en) 2003-04-24 2004-04-23 Macrolide-conjugates with anti-inflammatory activity
RU2005131937/04A RU2355699C2 (ru) 2003-04-24 2004-04-23 Макролидные конъюгаты с противовоспалительной активностью
SI200431768T SI2070940T1 (sl) 2003-04-24 2004-04-23 Makrolidni konjugati z antivnetno aktivnostjo
DK09075145.4T DK2070940T3 (da) 2003-04-24 2004-04-23 Makrolid-konjugater med antiinflammatorisk aktivitet
BRPI0410490-0A BRPI0410490A (pt) 2003-04-24 2004-04-23 composto de macrolìdeo, composição farmacêutica e método de tratamento compreendendo o mesmo
CNB2004800110487A CN100393741C (zh) 2003-04-24 2004-04-23 具有抗炎活性的大环内酯类配合物
AU2004232546A AU2004232546B2 (en) 2003-04-24 2004-04-23 Macrolide-conjugates with anti-inflammatory activity
HK06108841.8A HK1086842B (zh) 2003-04-24 2004-04-23 具有抗炎活性的大环内酯类配合物
DK04729157T DK1633771T3 (da) 2003-04-24 2004-04-23 Macrolid-konjugater med anti-inflammatorisk aktivitet
SI200431253T SI1633771T1 (sl) 2003-04-24 2004-04-23 Makrolidni konjugati s protivnetno aktivnostjo
JP2006506511A JP4613366B2 (ja) 2003-04-24 2004-04-23 抗炎症活性を有するマクロライドコンジュゲート
AT09075145T ATE518876T1 (de) 2003-04-24 2004-04-23 Macrolid-konjugate mit entzündungshemmender wirkung
KR1020057020252A KR101107336B1 (ko) 2003-04-24 2004-04-23 항염증 작용이 있는 마크로라이드 복합체
DE602004022047T DE602004022047D1 (de) 2003-04-24 2004-04-23 Macrolid-konjugate mit entzündungshemmenden eigenschaften
YU20050873A RS52621B (en) 2003-04-24 2004-04-23 CONJUGATED MACROLIDE WITH ANTI-INFLAMMATORY ACTION
ES09075145T ES2370371T3 (es) 2003-04-24 2004-04-23 Conjugados de macrólido con actividad antiinflamatoria.
PL09075145T PL2070940T3 (pl) 2003-04-24 2004-04-23 Makrolidowe koniugaty o aktywności przeciwzapalnej
PT09075145T PT2070940E (pt) 2003-04-24 2004-04-23 Conjugados de macrólidos com actividade anti-inflamatória
MXPA05011359A MXPA05011359A (es) 2003-04-24 2004-04-23 Conjugados macrolidos con actividad anti-inflamatoria.
CA2523081A CA2523081C (en) 2003-04-24 2004-04-23 Macrolide-conjugates with anti-inflammatory activity
ES04729157T ES2330109T3 (es) 2003-04-24 2004-04-23 Conjugados de macrolidos con actividad antiinflmatoria.
PL04729157T PL1633771T3 (pl) 2003-04-24 2004-04-23 Koniugaty makrolidowe o aktywności przeciwzapalnej
EP09075145A EP2070940B1 (en) 2003-04-24 2004-04-23 Macrolide-conjugates with anti-inflammatory activity
PCT/IB2004/001235 WO2004094449A1 (en) 2003-04-24 2004-04-23 Macrolide-conjugates with anti-inflammatory activity
ARP040101400A AR044083A1 (es) 2003-04-24 2004-04-23 Compuestos con actividad anti-inflamatoria
PT04729157T PT1633771E (pt) 2003-04-24 2004-04-23 Conjugados de macrolidos com actividade anti-inflamatória
EP04729157A EP1633771B1 (en) 2003-04-24 2004-04-23 Macrolide-conjugates with anti-inflammatory activity
ZA200508388A ZA200508388B (en) 2003-04-24 2005-10-17 Macrolide-Conjugates with anti-inflammatory activity
IS8141A IS2736B (is) 2003-04-24 2005-11-22 Makrólíðsamrunaefnasambönd@með@bólgueyðandi@virkni
NO20055535A NO333909B1 (no) 2003-04-24 2005-11-23 Makrolidkonjugater med anti-inflammatorisk aktivitet, farmasøytisk sammensetning og anvendelse
HK09106861.4A HK1129681B (zh) 2003-04-24 2009-07-24 具有抗炎活性的化合物
CY20091101070T CY1109491T1 (el) 2003-04-24 2009-10-14 Συζυγη μακρολιδων με αντιφλεγμονωδη δραση
IS8941A IS8941A (is) 2003-04-24 2010-12-29 Efnasambönd með bólgueyðandi virkni
HR20110763T HRP20110763T1 (hr) 2003-04-24 2011-10-19 Makrolidni konjugati s protuupalnom aktivnošću
CY20111101008T CY1111978T1 (el) 2003-04-24 2011-10-25 Συζυγη μακρολιδων με αντιφλεγμονωδη δραση
NO20130898A NO335552B1 (no) 2003-04-24 2013-06-28 Makrolidkonjugater med anti-inflammatorisk aktivitet, anvendelse derav og farmasøytisk sammensetning inneholdende en slik forbindelse

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HR20030324A HRP20030324A2 (en) 2003-04-24 2003-04-24 Compounds of antiinflammatory effect

Publications (1)

Publication Number Publication Date
HRP20030324A2 true HRP20030324A2 (en) 2005-02-28

Family

ID=33307078

Family Applications (3)

Application Number Title Priority Date Filing Date
HR20030324A HRP20030324A2 (en) 2003-04-24 2003-04-24 Compounds of antiinflammatory effect
HR20090551T HRP20090551T1 (hr) 2003-04-24 2004-04-23 Makrolidni konjugati s protuupalnom aktivnošću
HR20110763T HRP20110763T1 (hr) 2003-04-24 2011-10-19 Makrolidni konjugati s protuupalnom aktivnošću

Family Applications After (2)

Application Number Title Priority Date Filing Date
HR20090551T HRP20090551T1 (hr) 2003-04-24 2004-04-23 Makrolidni konjugati s protuupalnom aktivnošću
HR20110763T HRP20110763T1 (hr) 2003-04-24 2011-10-19 Makrolidni konjugati s protuupalnom aktivnošću

Country Status (27)

Country Link
US (1) US7579334B2 (zh)
EP (2) EP2070940B1 (zh)
JP (1) JP4613366B2 (zh)
KR (1) KR101107336B1 (zh)
CN (1) CN100393741C (zh)
AR (1) AR044083A1 (zh)
AT (1) ATE518876T1 (zh)
AU (1) AU2004232546B2 (zh)
BR (1) BRPI0410490A (zh)
CA (1) CA2523081C (zh)
CL (1) CL2004000872A1 (zh)
CY (2) CY1109491T1 (zh)
DE (1) DE602004022047D1 (zh)
DK (2) DK1633771T3 (zh)
ES (2) ES2370371T3 (zh)
HR (3) HRP20030324A2 (zh)
IS (2) IS2736B (zh)
ME (1) MEP34708A (zh)
MX (1) MXPA05011359A (zh)
NO (2) NO333909B1 (zh)
PL (2) PL1633771T3 (zh)
PT (2) PT1633771E (zh)
RS (1) RS52621B (zh)
RU (1) RU2355699C2 (zh)
SI (2) SI1633771T1 (zh)
WO (1) WO2004094449A1 (zh)
ZA (1) ZA200508388B (zh)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2070940A1 (en) 2003-04-24 2009-06-17 GlaxoSmithKline istrazivacki centar Zagreb d.o.o. Compounds with anti-inflammatory activity

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR043050A1 (es) 2002-09-26 2005-07-13 Rib X Pharmaceuticals Inc Compuestos heterociclicos bifuncionales y metodos para preparar y usar los mismos
US8202843B2 (en) 2004-02-27 2012-06-19 Rib-X Pharmaceuticals, Inc. Macrocyclic compounds and methods of making and using the same
EP1778292A2 (en) * 2004-08-12 2007-05-02 GlaxoSmithKline istrazivacki centar Zagreb d.o.o. Use of cell-specific conjugates for treatment of inflammatory diseases of the gastrointestinal tract
US20060183696A1 (en) * 2004-08-12 2006-08-17 Pliva-Istrazivacki Institut D.O.O. Use of immune cell specific conjugates for treatment of inflammatory diseases of gastrointestinal tract
AU2005298312A1 (en) * 2004-10-27 2006-05-04 Glaxosmithkline Istrazivacki Centar Zagreb D.O.O. Conjugates with anti-inflammatory activity
AU2006327181A1 (en) * 2005-12-22 2007-06-28 Hydra Biosciences, Inc. TRPA1 inhibitors for treating pain
WO2007093840A2 (en) * 2006-02-15 2007-08-23 Glaxosmithkline Istrazivacki Centar Zagreb D.O.O. Use of cell-specific conjugates for treatment of inflammatory diseases of the gastrointestinal tract
CA2717456A1 (en) * 2008-03-05 2009-09-11 Panacea Biotec Limited Modified release pharmaceutical compositions comprising mycophenolate and processes thereof
CN102838660B (zh) * 2011-06-23 2016-11-02 上海市第一人民医院 一种抑制炎症免疫反应的小肽及其应用
WO2014115167A2 (en) * 2013-01-23 2014-07-31 Sphaera Pharma Pvt. Ltd. Novel compounds of 11beta-hydroxy-steroids for use in mitochondria biogenesis and diseases associated with mitochondrial dysfunction or depletion
US20140256666A1 (en) * 2013-03-08 2014-09-11 Allergan, Inc. Antibiotic conjugates with nonsteroidal anti-inflammatory drugs
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