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HK8594A - Anti-tumor agents - Google Patents

Anti-tumor agents

Info

Publication number
HK8594A
HK8594A HK85/94A HK8594A HK8594A HK 8594 A HK8594 A HK 8594A HK 85/94 A HK85/94 A HK 85/94A HK 8594 A HK8594 A HK 8594A HK 8594 A HK8594 A HK 8594A
Authority
HK
Hong Kong
Prior art keywords
tumor agents
tumor
agents
Prior art date
Application number
HK85/94A
Other languages
English (en)
Inventor
Leslie Richard Hughes
Original Assignee
Ici Plc
Nat Res Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ici Plc, Nat Res Dev filed Critical Ici Plc
Publication of HK8594A publication Critical patent/HK8594A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/88—Oxygen atoms
    • C07D239/90—Oxygen atoms with acyclic radicals attached in position 2 or 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • C07D239/96—Two oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
HK85/94A 1986-03-27 1994-01-21 Anti-tumor agents HK8594A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB868607683A GB8607683D0 (en) 1986-03-27 1986-03-27 Anti-tumor agents

Publications (1)

Publication Number Publication Date
HK8594A true HK8594A (en) 1994-02-04

Family

ID=10595358

Family Applications (1)

Application Number Title Priority Date Filing Date
HK85/94A HK8594A (en) 1986-03-27 1994-01-21 Anti-tumor agents

Country Status (22)

Country Link
US (2) US4992550A (no)
EP (1) EP0239362B1 (no)
JP (1) JPH0657699B2 (no)
AR (1) AR244213A1 (no)
AT (1) ATE70057T1 (no)
AU (1) AU592628B2 (no)
CA (1) CA1285943C (no)
DE (1) DE3774909D1 (no)
DK (1) DK166621B1 (no)
ES (1) ES2038170T3 (no)
FI (1) FI89912C (no)
GB (2) GB8607683D0 (no)
GR (1) GR3003282T3 (no)
HK (1) HK8594A (no)
HU (1) HU197317B (no)
IE (1) IE60302B1 (no)
IL (1) IL81924A (no)
LU (1) LU88797I2 (no)
NL (1) NL970024I2 (no)
NO (2) NO173545C (no)
PT (1) PT84571B (no)
ZA (1) ZA871998B (no)

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GB8513754D0 (en) * 1985-05-31 1985-07-03 Jones T R Anti-cancer quinazoline derivatives
GB8625019D0 (en) * 1986-10-18 1986-11-19 Wellcome Found Compounds
GB8707053D0 (en) * 1987-03-25 1987-04-29 Ici Plc Anti-tumour agents
US4857530A (en) * 1987-11-03 1989-08-15 Warner-Lambert Company Substituted quinazolinones as anticancer agents
GB8727737D0 (en) * 1987-11-26 1987-12-31 Ici Plc Antitumour agents
US5019577A (en) * 1988-04-15 1991-05-28 Burroughs Welcome Co. Novel compounds and use
US4940713A (en) * 1988-04-15 1990-07-10 Burroughs Wellcome Co. Substituted glutamic acids
GB8809978D0 (en) * 1988-04-27 1988-06-02 Ici Plc Anti-tumour agents
EP0365763A1 (en) * 1988-09-30 1990-05-02 Agouron Pharmaceuticals, Inc. Antiproliferative cyclic compounds
US5252573A (en) * 1988-12-15 1993-10-12 Imperial Chemical Industries Plc Anti-tumor agents
GB8829296D0 (en) * 1988-12-15 1989-01-25 Ici Plc Anti-tumour compounds
US5286726A (en) * 1990-04-12 1994-02-15 The Regents Of The University Of Michigan Difluoroglutamic acid conjugates with folates and anti-folates for the treatment of neoplastic diseases
ZA913730B (en) * 1990-05-30 1992-02-26 Ici Plc Anti-tumor compounds
GB9013615D0 (en) * 1990-06-19 1990-08-08 Wellcome Found Pharmaceutical compounds
US5290780A (en) * 1991-01-30 1994-03-01 American Cyanamid Co. Angiotensin II receptor blocking 2,3,6 substituted quinazolinones
GB9105771D0 (en) * 1991-03-19 1991-05-01 Cancer Res Inst Royal Anti-cancer compounds
NZ243082A (en) 1991-06-28 1995-02-24 Ici Plc 4-anilino-quinazoline derivatives; pharmaceutical compositions, preparatory processes, and use thereof
EP0530537B1 (en) * 1991-08-12 1997-01-08 Takeda Chemical Industries, Ltd. Condensed pyrimidine derivatives, their production and use as antitumor agents
US5145854A (en) * 1991-11-27 1992-09-08 Nair Madhavan G 1-formyl-5,8,10-trideazafolates
GB9205320D0 (en) * 1992-03-11 1992-04-22 Ici Plc Anti-tumour compounds
GB9205907D0 (en) * 1992-03-18 1992-04-29 Cancer Res Inst Royal Anti-cancer compounds
ES2049659B1 (es) * 1992-10-08 1994-10-16 Ici Plc Una composicion farmaceutica a base de derivados de quinazolina con actividad anti-cancerigena.
GB9223352D0 (en) * 1992-11-06 1992-12-23 Ici Plc Tricyclic compounds
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Also Published As

Publication number Publication date
JPH0657699B2 (ja) 1994-08-03
NL970024I2 (nl) 1997-10-01
NO1998020I1 (no) 1998-09-28
NL970024I1 (nl) 1997-09-01
FI871139A0 (fi) 1987-03-16
PT84571B (pt) 1989-11-30
ZA871998B (en) 1987-11-25
FI89912B (fi) 1993-08-31
DK155087A (da) 1987-09-28
EP0239362A3 (en) 1989-07-05
DK155087D0 (da) 1987-03-26
AU7047287A (en) 1987-10-01
US5081124A (en) 1992-01-14
FI89912C (fi) 1993-12-10
LU88797I2 (fr) 1996-11-05
GB8607683D0 (en) 1986-04-30
IE870699L (en) 1987-09-27
ATE70057T1 (de) 1991-12-15
EP0239362B1 (en) 1991-12-04
ES2038170T3 (es) 1993-07-16
GR3003282T3 (en) 1993-02-17
HUT43835A (en) 1987-12-28
NO871266D0 (no) 1987-03-26
NO871266L (no) 1987-09-28
AR244213A1 (es) 1993-10-29
CA1285943C (en) 1991-07-09
JPH01125373A (ja) 1989-05-17
US4992550A (en) 1991-02-12
EP0239362A2 (en) 1987-09-30
FI871139A (fi) 1987-09-28
IL81924A (en) 1991-07-18
IE60302B1 (en) 1994-06-29
DE3774909D1 (de) 1992-01-16
PT84571A (en) 1987-04-01
DK166621B1 (da) 1993-06-21
NO173545B (no) 1993-09-20
AU592628B2 (en) 1990-01-18
HU197317B (en) 1989-03-28
GB2188319A (en) 1987-09-30
NO173545C (no) 1993-12-29
GB8706948D0 (en) 1987-04-29
GB2188319B (en) 1989-12-13

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