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HK49496A - Process for the preparation of 7-substituted-hept-6-enoic and-heptanoic acids and derivatives thereof - Google Patents

Process for the preparation of 7-substituted-hept-6-enoic and-heptanoic acids and derivatives thereof

Info

Publication number
HK49496A
HK49496A HK49496A HK49496A HK49496A HK 49496 A HK49496 A HK 49496A HK 49496 A HK49496 A HK 49496A HK 49496 A HK49496 A HK 49496A HK 49496 A HK49496 A HK 49496A
Authority
HK
Hong Kong
Prior art keywords
enoic
hept
derivatives
substituted
preparation
Prior art date
Application number
HK49496A
Other languages
English (en)
Inventor
Kau-Ming Chen
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26945992&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK49496(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of HK49496A publication Critical patent/HK49496A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C223/00Compounds containing amino and —CHO groups bound to the same carbon skeleton
    • C07C223/02Compounds containing amino and —CHO groups bound to the same carbon skeleton having amino groups bound to acyclic carbon atoms of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/367Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of functional groups containing oxygen only in singly bound form
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/42Unsaturated compounds containing hydroxy or O-metal groups
    • C07C59/48Unsaturated compounds containing hydroxy or O-metal groups containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/12Radicals substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/24Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an alkyl or cycloalkyl radical attached to the ring nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Steroid Compounds (AREA)
HK49496A 1988-10-13 1996-03-21 Process for the preparation of 7-substituted-hept-6-enoic and-heptanoic acids and derivatives thereof HK49496A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25747588A 1988-10-13 1988-10-13
US35553189A 1989-05-22 1989-05-22

Publications (1)

Publication Number Publication Date
HK49496A true HK49496A (en) 1996-03-29

Family

ID=26945992

Family Applications (1)

Application Number Title Priority Date Filing Date
HK49496A HK49496A (en) 1988-10-13 1996-03-21 Process for the preparation of 7-substituted-hept-6-enoic and-heptanoic acids and derivatives thereof

Country Status (24)

Country Link
EP (2) EP0363934B1 (bg)
JP (1) JP2853227B2 (bg)
KR (1) KR0162656B1 (bg)
AT (1) ATE99281T1 (bg)
AU (1) AU636122B2 (bg)
BG (1) BG60555B1 (bg)
CA (1) CA2000553C (bg)
CZ (1) CZ283316B6 (bg)
DE (1) DE68911834T2 (bg)
DK (1) DK175073B1 (bg)
ES (1) ES2060712T3 (bg)
FI (1) FI98063C (bg)
HK (1) HK49496A (bg)
HU (1) HU207993B (bg)
IE (2) IE940109L (bg)
IL (1) IL91941A (bg)
MY (1) MY105067A (bg)
NO (1) NO174623C (bg)
NZ (1) NZ230973A (bg)
RO (1) RO109732B1 (bg)
SG (1) SG139553A1 (bg)
SK (1) SK579789A3 (bg)
WO (1) WO1990003962A1 (bg)
YU (1) YU48466B (bg)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5118853A (en) * 1988-10-13 1992-06-02 Sandoz Ltd. Processes for the synthesis of 3-disubstituted aminoacroleins
US5290946A (en) * 1988-10-13 1994-03-01 Sandoz Ltd. Processes for the synthesis of 3-(substituted indolyl-2-yl)propenaldehydes
CA2027179A1 (en) * 1989-10-10 1991-04-11 Barry C. Ross Chemical compounds
DE4424525A1 (de) * 1994-07-12 1995-01-26 Elmar Meyer Dauermagnet-Kolbenmotor
GT199800127A (es) 1997-08-29 2000-02-01 Combinaciones terapeuticas.
IL148127A0 (en) 1999-08-30 2002-09-12 Aventis Pharma Gmbh Use of inhibitors of the renin-angiotensin system in the prevention of cardiovascular events
JP2003535077A (ja) 2000-05-26 2003-11-25 チバ スペシャルティ ケミカルズ ホールディング インコーポレーテッド インドール誘導体を製造する方法、および該方法の中間体
US7777006B2 (en) 2002-12-31 2010-08-17 Csl Behring L.L.C. Method for purification of alpha-1-antitrypsin
WO2004094377A1 (ja) * 2003-04-24 2004-11-04 Daicel Chemical Industries Ltd. 光学活性なジヒドロキシヘプテン酸エステルの分離方法
ATE417827T1 (de) 2003-06-18 2009-01-15 Teva Pharma Fluvastatin-natrium in der kristallform xiv, verfahren zu deren herstellung, diese enthaltende zusammensetzungen und enstprechende anwendungsverfahren
US7368581B2 (en) 2003-06-18 2008-05-06 Teva Pharmaceutical Industries Ltd. Process for the preparation of fluvastatin sodium crystal from XIV
US7368468B2 (en) 2003-06-18 2008-05-06 Teva Pharmaceutical Industries Ltd. Fluvastatin sodium crystal forms XIV, LXXIII, LXXIX, LXXX and LXXXVII, processes for preparing them, compositions containing them and methods of using them
US8415364B2 (en) 2003-11-26 2013-04-09 Duke University Method of preventing or treating glaucoma
US7851624B2 (en) 2003-12-24 2010-12-14 Teva Pharamaceutical Industries Ltd. Triol form of rosuvastatin and synthesis of rosuvastatin
US20060211752A1 (en) 2004-03-16 2006-09-21 Kohn Leonard D Use of phenylmethimazoles, methimazole derivatives, and tautomeric cyclic thiones for the treatment of autoimmune/inflammatory diseases associated with toll-like receptor overexpression
US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
US7888376B2 (en) 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
EP1847529B1 (en) 2006-04-20 2009-05-20 F.I.S. Fabbrica Italiana Sintetici S.P.A. Process for the preparation of Fluvastatin Sodium salt
EP2327682A1 (en) 2009-10-29 2011-06-01 KRKA, D.D., Novo Mesto Use of amphiphilic compounds for controlled crystallization of statins and statin intermediates
WO2010069593A1 (en) 2008-12-19 2010-06-24 Krka, D. D., Novo Mesto Use of amphiphilic compounds for controlled crystallization of statins and statin intermediates
AU2013214693B2 (en) 2012-02-02 2017-02-23 Kenneth Gek-Jin OOI Improvements in tear film stability
RU2618628C1 (ru) 2013-04-17 2017-05-05 Пфайзер Инк. Производные N-пиперидин-3-илбензамида для лечения сердечно-сосудистых заболеваний
WO2016055901A1 (en) 2014-10-08 2016-04-14 Pfizer Inc. Substituted amide compounds
CA3125765A1 (en) 2019-01-18 2020-07-23 Astrazeneca Ab Pcsk9 inhibitors and methods of use thereof

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB945536A (en) * 1961-09-08 1964-01-02 Istituto Chemioterapico Method of preparing ª -amino-acroleins
US4739073A (en) * 1983-11-04 1988-04-19 Sandoz Pharmaceuticals Corp. Intermediates in the synthesis of indole analogs of mevalonolactone and derivatives thereof
HU204253B (en) * 1982-11-22 1991-12-30 Sandoz Ag Process for producing mevalonolactone analogues and derivatives and pharmaceutical compositions containing them
US4571428A (en) * 1983-07-08 1986-02-18 Sandoz, Inc. 6-Substituted-4-hydroxy-tetrahydropyran-2-ones
US4650890A (en) * 1984-04-03 1987-03-17 Sandoz Corp. Preparation of olefinic compounds and intermediates thereof
DE3582674D1 (de) * 1984-06-22 1991-05-29 Sandoz Ag Pyrazolanaloge von mevalonolakton und abkoemmlinge davon, verfahren zu deren herstellung und deren verwendung.
ATE60571T1 (de) * 1984-12-04 1991-02-15 Sandoz Ag Inden-analoga von mevalonolakton und ihre derivate.
US4668794A (en) * 1985-05-22 1987-05-26 Sandoz Pharm. Corp. Intermediate imidazole acrolein analogs
JPS6322056A (ja) * 1986-04-30 1988-01-29 サンド・アクチエンゲゼルシヤフト オレフイン性化合物の製造法
PT85662B (pt) * 1986-09-10 1990-06-29 Sandoz Sa Processo para a preparacao de derivados de aza-indol e de indolizina e de composicoes farmaceuticas que os contem

Also Published As

Publication number Publication date
ES2060712T3 (es) 1994-12-01
IE63477B1 (en) 1995-04-19
YU197389A (en) 1990-12-31
AU4344889A (en) 1990-05-01
DK144690D0 (da) 1990-06-13
ATE99281T1 (de) 1994-01-15
KR900701723A (ko) 1990-12-04
FI902935A0 (fi) 1990-06-12
BG92179A (bg) 1993-12-24
WO1990003962A1 (en) 1990-04-19
AU636122B2 (en) 1993-04-22
DK144690A (da) 1990-06-13
KR0162656B1 (ko) 1999-01-15
SG139553A1 (en) 2008-02-29
IL91941A0 (en) 1990-06-10
JPH03501735A (ja) 1991-04-18
DK175073B1 (da) 2004-05-24
IL91941A (en) 1994-10-21
DE68911834T2 (de) 1994-06-23
CZ283316B6 (cs) 1998-02-18
NO174623C (no) 1994-06-08
NO174623B (no) 1994-02-28
RO109732B1 (ro) 1995-05-30
JP2853227B2 (ja) 1999-02-03
NZ230973A (en) 1993-03-26
BG60555B1 (en) 1995-08-28
SK280845B6 (sk) 2000-08-14
HUT53860A (en) 1990-12-28
MY105067A (en) 1994-07-30
HU207993B (en) 1993-07-28
EP0363934B1 (en) 1993-12-29
CZ579789A3 (en) 1997-11-12
EP0562643A2 (en) 1993-09-29
DE68911834D1 (de) 1994-02-10
NO902598L (no) 1990-08-07
EP0562643A3 (en) 1994-05-18
FI98063C (fi) 1997-04-10
CA2000553A1 (en) 1990-04-13
SK579789A3 (en) 2000-08-14
YU48466B (sh) 1998-08-14
CA2000553C (en) 2001-12-04
EP0363934A1 (en) 1990-04-18
FI98063B (fi) 1996-12-31
NO902598D0 (no) 1990-06-12
HU896048D0 (en) 1990-11-28
IE893277L (en) 1990-04-13
IE940109L (en) 1990-04-13

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Legal Events

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PF Patent in force
PE Patent expired

Effective date: 20091010