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HK1243764A1 - 用於富集循環腫瘤dna的方法 - Google Patents

用於富集循環腫瘤dna的方法

Info

Publication number
HK1243764A1
HK1243764A1 HK18103101.0A HK18103101A HK1243764A1 HK 1243764 A1 HK1243764 A1 HK 1243764A1 HK 18103101 A HK18103101 A HK 18103101A HK 1243764 A1 HK1243764 A1 HK 1243764A1
Authority
HK
Hong Kong
Prior art keywords
enrichment
circulating tumor
tumor dna
dna
circulating
Prior art date
Application number
HK18103101.0A
Other languages
English (en)
Inventor
Jacob Vincent Micallef
Marielle Herzog
Mark Edward Eccleston
Original Assignee
Belgian Volition Sprl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=54427791&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1243764(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GBGB1419225.6A external-priority patent/GB201419225D0/en
Priority claimed from GB201419299A external-priority patent/GB201419299D0/en
Application filed by Belgian Volition Sprl filed Critical Belgian Volition Sprl
Publication of HK1243764A1 publication Critical patent/HK1243764A1/zh

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6875—Nucleoproteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/62—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosols; by investigating electric discharges, e.g. emission of cathode
    • G01N27/622—Ion mobility spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2560/00—Chemical aspects of mass spectrometric analysis of biological material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/70—Mechanisms involved in disease identification
    • G01N2800/7023—(Hyper)proliferation
    • G01N2800/7028—Cancer

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plant Pathology (AREA)
  • Electrochemistry (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Biophysics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
HK18103101.0A 2014-10-29 2018-03-05 用於富集循環腫瘤dna的方法 HK1243764A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1419225.6A GB201419225D0 (en) 2014-10-29 2014-10-29 Method for the enrichment of circulating tumor DNA
GB201419299A GB201419299D0 (en) 2014-10-30 2014-10-30 Method for the enrichment of circulating tumour DNA
PCT/GB2015/053238 WO2016067029A1 (en) 2014-10-29 2015-10-29 Method for the enrichment of circulating tumor dna

Publications (1)

Publication Number Publication Date
HK1243764A1 true HK1243764A1 (zh) 2018-07-20

Family

ID=54427791

Family Applications (1)

Application Number Title Priority Date Filing Date
HK18103101.0A HK1243764A1 (zh) 2014-10-29 2018-03-05 用於富集循環腫瘤dna的方法

Country Status (13)

Country Link
US (2) US20180024141A1 (zh)
EP (2) EP3213084B2 (zh)
JP (1) JP6721599B2 (zh)
CN (2) CN107209190B (zh)
AU (1) AU2015340378B2 (zh)
CA (1) CA2965752C (zh)
DK (1) DK3213084T4 (zh)
ES (1) ES2839973T3 (zh)
HK (1) HK1243764A1 (zh)
IL (1) IL251896A0 (zh)
PL (1) PL3213084T3 (zh)
SG (2) SG10201903822XA (zh)
WO (1) WO2016067029A1 (zh)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4155401A1 (en) 2012-03-02 2023-03-29 Sequenom, Inc. Methods and processes for non-invasive assessment of genetic variations
EP2971100A1 (en) 2013-03-13 2016-01-20 Sequenom, Inc. Primers for dna methylation analysis
EP3117011B1 (en) 2014-03-13 2020-05-06 Sequenom, Inc. Methods and processes for non-invasive assessment of genetic variations
CN106544341A (zh) * 2017-01-17 2017-03-29 上海亿康医学检验所有限公司 高效检测样本中的ctDNA的方法
CN117138146A (zh) * 2017-09-18 2023-12-01 圣特萨斯股份公司 用于针对循环无细胞dna纯化血液的方法和装置
CN109932224A (zh) * 2017-12-18 2019-06-25 中国科学院大连化学物理研究所 一种富集提取循环肿瘤dna的方法
CN112119166A (zh) * 2018-03-13 2020-12-22 耶路撒冷希伯来大学伊萨姆研发有限公司 无细胞dna染色质免疫沉淀的诊断应用
BR112020023587A2 (pt) * 2018-05-18 2021-02-09 The Johns Hopkins University método para determinar um perfil de fragmentação de dna livre de células (cfdna), método para identificar um mamífero como tendo câncer, método de identificação do tecido de origem de um câncer e método para tratar um mamífero com câncer
GB201818965D0 (en) 2018-11-21 2019-01-09 Belgian Volition Sprl Method for the detection of colorectal cancer
GB201818963D0 (en) 2018-11-21 2019-01-09 Belgian Volition Sprl Methof for the detection of prostate cancer
CN109841265B (zh) * 2019-02-22 2021-09-21 清华大学 使用片段化模式确定血浆游离核酸分子组织来源的方法和系统及应用
GB201906201D0 (en) 2019-05-02 2019-06-19 Belgian Voltion Sprl Method for the detection of protate cancer
GB201906199D0 (en) 2019-05-02 2019-06-19 Belgian Volition Sprl Method for the detection of cancer
EP4041914A1 (en) * 2019-10-04 2022-08-17 Santersus AG Method for isolating and analyzing cell free dna
JP7349104B2 (ja) * 2019-11-13 2023-09-22 株式会社島津製作所 ベロ毒素の検出方法
KR20220110794A (ko) 2019-12-02 2022-08-09 벨지언 볼리션 에스알엘 바이오마커로서의 무세포 뉴클레오솜의 사용
WO2021236993A1 (en) * 2020-05-22 2021-11-25 Bloodq, Inc. Methods for characterizing cell-free nucleic acid fragments
GB202117799D0 (en) 2021-12-09 2022-01-26 Belgian Volition Srl Method for the detection of blood cancer
EP4453241A1 (en) * 2021-12-21 2024-10-30 Guardant Health, Inc. Methods and systems for combinatorial chromatin-ip sequencing
US12053567B2 (en) 2021-12-27 2024-08-06 Santersus Ag Method and device for removal of circulating cell free DNA
WO2023170298A1 (en) 2022-03-11 2023-09-14 Belgian Volition Srl Differential diagnosis method
WO2024042210A1 (en) * 2022-08-25 2024-02-29 Belgian Volition Srl Method for measuring cell free chromatin
WO2024148280A1 (en) 2023-01-06 2024-07-11 Ideaya Biosciences, Inc. Treatment of er+ breast cancer comprising homologous recombination deficiency using parc inhibitor
WO2024223947A1 (en) 2023-04-28 2024-10-31 Belgian Volition Srl Use of cell free nucleosomes as biomarkers of carcinomas
GB202307768D0 (en) 2023-05-24 2023-07-05 Belgian Volition Srl Use of cell free nucleosomes as biomarkers
GB202310137D0 (en) 2023-07-03 2023-08-16 Belgian Volition Srl Method for the detection of cancer
WO2025012440A1 (en) 2023-07-13 2025-01-16 Belgian Volition Srl Method for detection of the potential of a body fluid sample to produce extracellular traps

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0319376D0 (en) 2003-08-18 2003-09-17 Chroma Therapeutics Ltd Histone modification detection
US20060115482A1 (en) * 2004-04-27 2006-06-01 The Regents Of The University Of California Modifications of histone proteins as indicators of cell proliferation and differentiation
WO2007121276A2 (en) * 2006-04-12 2007-10-25 Biocept, Inc. Enrichment of circulating fetal dna
EP2062912A1 (en) * 2007-11-26 2009-05-27 Koninklijke Philips Electronics N.V. Selective enrichment of post-translationally modified proteins and/or peptides
US20100240054A1 (en) * 2008-09-22 2010-09-23 Biocept, Inc. Identification and isolation of fetal cells and nucleic acid
EP2419737A4 (en) * 2009-04-14 2013-02-13 Univ California HISTON MODIFYING PATTERN FOR CLINICAL DIAGNOSIS AND FORECASTING CANCER
US20140213475A1 (en) * 2011-07-14 2014-07-31 University Of Massachusetts Methods of diagnosing cancer using epigenetic biomarkers
GB201115095D0 (en) † 2011-09-01 2011-10-19 Singapore Volition Pte Ltd Method for detecting nucleosomes containing nucleotides
GB201115098D0 (en) 2011-09-01 2011-10-19 Belgian Volition Sa Method for detecting nucleosomes containing histone variants
EP2782928B1 (en) * 2011-11-21 2017-01-04 The Royal Institution for the Advancement of Learning / McGill University Mutations of histone proteins associated with proliferative disorders
MX356986B (es) 2011-12-07 2018-06-22 Singapore Volition Pte Ltd Metodo para detectar aductos de nucleosomas.
EP4155401A1 (en) * 2012-03-02 2023-03-29 Sequenom, Inc. Methods and processes for non-invasive assessment of genetic variations
US9388213B2 (en) * 2012-09-10 2016-07-12 The Rockefeller University Polycomb repressive complex 2 (PRC2) inhibitors and uses thereof

Also Published As

Publication number Publication date
EP3213084B1 (en) 2020-11-25
CN111505305B (zh) 2023-10-17
SG10201903822XA (en) 2019-05-30
EP3809140A1 (en) 2021-04-21
PL3213084T3 (pl) 2021-07-26
AU2015340378A1 (en) 2017-05-11
AU2015340378B2 (en) 2021-08-12
CA2965752A1 (en) 2016-05-06
WO2016067029A1 (en) 2016-05-06
CN111505305A (zh) 2020-08-07
CA2965752C (en) 2024-04-02
JP2017534300A (ja) 2017-11-24
EP3213084A1 (en) 2017-09-06
IL251896A0 (en) 2017-06-29
CN107209190B (zh) 2021-07-16
NZ731116A (en) 2024-03-22
DK3213084T4 (da) 2024-03-18
SG11201702978VA (en) 2017-05-30
JP6721599B2 (ja) 2020-07-15
US20180024141A1 (en) 2018-01-25
EP3213084B2 (en) 2023-12-13
ES2839973T3 (es) 2021-07-06
CN107209190A (zh) 2017-09-26
US20220334128A1 (en) 2022-10-20
DK3213084T3 (da) 2021-01-18

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AM43 Amendment of standard patent following opposition or revocation proceedings in the designated patent office (acc. sect 43 patent ordinance)