HK1220233A1 - 用於神經變性疾病的細胞性發現平台 - Google Patents
用於神經變性疾病的細胞性發現平台Info
- Publication number
- HK1220233A1 HK1220233A1 HK16108219.0A HK16108219A HK1220233A1 HK 1220233 A1 HK1220233 A1 HK 1220233A1 HK 16108219 A HK16108219 A HK 16108219A HK 1220233 A1 HK1220233 A1 HK 1220233A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- neurodegenerative diseases
- discovery platform
- cellular
- cellular discovery
- platform
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
- G01N33/5058—Neurological cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/136—Screening for pharmacological compounds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/10—Screening for compounds of potential therapeutic value involving cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Food Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- General Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Tropical Medicine & Parasitology (AREA)
- Toxicology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361794870P | 2013-03-15 | 2013-03-15 | |
| US201361857648P | 2013-07-23 | 2013-07-23 | |
| US201361895274P | 2013-10-24 | 2013-10-24 | |
| PCT/US2014/030838 WO2014145975A2 (en) | 2013-03-15 | 2014-03-17 | Cellular discovery platform for neurodegenerative diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1220233A1 true HK1220233A1 (zh) | 2017-04-28 |
Family
ID=51538585
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK16108152.9A HK1220232A1 (zh) | 2013-03-15 | 2016-07-12 | 用於神經變性疾病的細胞性發現平台 |
| HK16108219.0A HK1220233A1 (zh) | 2013-03-15 | 2016-07-13 | 用於神經變性疾病的細胞性發現平台 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK16108152.9A HK1220232A1 (zh) | 2013-03-15 | 2016-07-12 | 用於神經變性疾病的細胞性發現平台 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US11047848B2 (zh) |
| EP (2) | EP3736343A1 (zh) |
| JP (2) | JP7182852B2 (zh) |
| CN (1) | CN105247070A (zh) |
| BR (1) | BR112015023533A2 (zh) |
| CA (1) | CA2906197A1 (zh) |
| HK (2) | HK1220232A1 (zh) |
| IL (1) | IL241310B (zh) |
| WO (1) | WO2014145975A2 (zh) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016033501A1 (en) | 2014-08-28 | 2016-03-03 | Robert John Petcavich | Method of fabricating cell arrays and uses thereof |
| US11261453B2 (en) | 2014-09-12 | 2022-03-01 | Whitehead Institute For Biomedical Research | Cells expressing apolipoprotein E and uses thereof |
| KR101816103B1 (ko) * | 2015-04-13 | 2018-01-08 | 고려대학교 산학협력단 | 소분자 화합물을 이용한 인간 섬유아세포를 신경줄기세포로 직접 전환하는 방법 |
| WO2016210313A1 (en) * | 2015-06-24 | 2016-12-29 | Whitehead Institute For Biomedical Research | Culture medium for generating microglia from pluripotent stem cells and related methods |
| US11248212B2 (en) | 2015-06-30 | 2022-02-15 | StemoniX Inc. | Surface energy directed cell self assembly |
| US10760053B2 (en) | 2015-10-15 | 2020-09-01 | StemoniX Inc. | Method of manufacturing or differentiating mammalian pluripotent stem cells or progenitor cells using a hollow fiber bioreactor |
| CN105838691B (zh) * | 2016-04-18 | 2018-07-06 | 浙江大学 | 一对转录激活子样效应因子核酸酶及其编码基因与应用 |
| CN106148286B (zh) * | 2016-06-29 | 2019-10-29 | 牛刚 | 一种用于检测热原的细胞模型的构建方法和细胞模型及热原检测试剂盒 |
| JP7288853B2 (ja) * | 2017-01-25 | 2023-06-08 | ホワイトヘッド・インスティテュート・フォー・バイオメディカル・リサーチ | ゲノムネットワークを構築するための方法およびその使用 |
| US10675328B2 (en) | 2017-02-14 | 2020-06-09 | Children's Hospital Medical Center | Compositions and methods for treatment of Gcase related disease states |
| CN106916907A (zh) * | 2017-05-04 | 2017-07-04 | 张家港蓝苏生物工程有限公司 | 一种特异性检测单纯疱疹病毒ⅰ、ⅱ型核酸的荧光pcr方法及试剂盒 |
| EP3694536A4 (en) * | 2017-10-12 | 2021-08-18 | The Regents of The University of California | CELL-BASED SEEDING ASSAY FOR HUNTINGTINE AGGREGATION |
| CN108913614B (zh) * | 2018-07-20 | 2022-11-04 | 江南大学 | 一种调节酿酒酵母氧胁迫的方法 |
| WO2020047043A1 (en) | 2018-08-28 | 2020-03-05 | Lenzi Tommaso | Variable transmission for assistive prosthesis device |
| KR102143320B1 (ko) * | 2018-08-28 | 2020-08-12 | 주식회사 스템랩 | 합성 메신저 rna를 이용하여 소변세포를 신경줄기세포로 직접 역분화하는 방법 |
| WO2020068731A1 (en) * | 2018-09-25 | 2020-04-02 | The General Hospital Corporation | Methods for integrating cell gene expression data from multiple single-cell data sets and uses thereof |
| EP3894578A4 (en) * | 2018-12-13 | 2022-12-14 | Ramot at Tel-Aviv University Ltd. | INTEGRATED DRUG DISCOVERY PLATFORM FOR INHERITED METABOLIC DISEASES |
| KR20210124374A (ko) | 2019-02-08 | 2021-10-14 | 듀포인트 테라퓨틱스, 인크. | 화합물의 응축물-연관된 특징을 특징규명하는 방법 및 그의 용도 |
| EP4031876A1 (en) * | 2019-09-18 | 2022-07-27 | Dewpoint Therapeutics, Inc. | Methods of screening for condensate-associated specificity and uses thereof |
| CA3154805A1 (en) * | 2019-10-18 | 2021-04-22 | Iosif PEDIADITAKIS | Brain-chip modeling neurodegeneration and neuroinflammation in parkinson's disease |
| WO2021158184A1 (en) * | 2020-02-07 | 2021-08-12 | Vidyasirimedhi Institute Of Science And Technology | Method of producing modified amyloid precursor protein anchored with detectable moieties and modified amyloid peptides derived thereof |
| WO2021188947A1 (en) | 2020-03-20 | 2021-09-23 | University Of Utah Research Foundation | Self-aligning mechanisms in passive and powered exoskeletons |
| WO2022126486A1 (zh) * | 2020-12-17 | 2022-06-23 | 深圳先进技术研究院 | 一种工程化神经细胞及其制备方法和应用 |
| WO2024026115A2 (en) * | 2022-07-28 | 2024-02-01 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Protein aggregation assay and methods of using the same |
| CN117050945B (zh) * | 2023-10-11 | 2024-01-26 | 北京市眼科研究所 | 体外培养类玻璃体的方法 |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69233061T3 (de) * | 1991-07-08 | 2008-07-10 | Neurospheres Holding Ltd., Calgary | Auf wachstumsfaktoren reagierende neurale vorläuferzellen, die in vitro vermehrt werden können. |
| US5843780A (en) | 1995-01-20 | 1998-12-01 | Wisconsin Alumni Research Foundation | Primate embryonic stem cells |
| EP1259637A2 (en) * | 2000-03-02 | 2002-11-27 | McGILL UNIVERSITY | Caspase-inhibitory-factor (cif) and uses thereof |
| US7118737B2 (en) | 2000-09-08 | 2006-10-10 | Amylin Pharmaceuticals, Inc. | Polymer-modified synthetic proteins |
| EP1392849B2 (en) | 2001-02-15 | 2012-01-18 | University Of Chicago | Yeast screens for agents affecting protein folding |
| US7432104B2 (en) | 2001-08-06 | 2008-10-07 | Bresgen Inc. | Methods for the culture of human embryonic stem cells on human feeder cells |
| US7452670B2 (en) | 2003-12-04 | 2008-11-18 | University Of Washington | Methods of identifying agents that diminish cellular toxicity associated with an α-synuclein polypeptide of Parkinson's disease in yeast |
| CA2563087A1 (en) * | 2004-04-09 | 2005-12-15 | Ronald S. Goldstein | Methods for generating neuronal cells from human embryonic stem cells and uses thereof |
| NZ588432A (en) | 2004-09-17 | 2012-03-30 | Whitehead Biomedical Inst | Compounds, Compositions and Methods of Inhibiting Alpha-Synuclein Toxicity |
| CA2589700A1 (en) | 2004-12-01 | 2006-07-13 | Whitehead Institute For Biomedical Research | Modulators of alpha-synuclein toxicity |
| JP2008545628A (ja) | 2005-05-13 | 2008-12-18 | ホワイトヘッド インスティテュート フォー バイオメディカル リサーチ | α−シヌクレイン毒性のモジュレーター |
| US20090227032A1 (en) | 2005-12-13 | 2009-09-10 | Kyoto University | Nuclear reprogramming factor and induced pluripotent stem cells |
| US20090010894A1 (en) | 2005-12-23 | 2009-01-08 | The Parkinson's Institute | Methods and systems for identifying compounds that modulate alpha-synuclein aggregation |
| BRPI0709699A2 (pt) | 2006-03-29 | 2011-07-26 | Foldrx Pharmaceuticals Inc | inibiÇço da toxidez da alfa-sinucleina |
| RU2502799C2 (ru) | 2007-04-07 | 2013-12-27 | Уайтхед Инститьют Фор Биомедикал Рисёч | Способ перепрограммирования соматических клеток |
| US7861880B2 (en) * | 2007-06-28 | 2011-01-04 | Britt Mark W | Portable and/or collapsible containers having pliable surfaces |
| US9102919B2 (en) | 2007-08-31 | 2015-08-11 | Whitehead Institute For Biomedical Research | WNT pathway stimulation in reprogramming somatic cells with nuclear reprogramming factors |
| WO2009086306A1 (en) | 2007-12-21 | 2009-07-09 | Whitehead Institute For Biomedical Research | Modulators of alpha-synuclein toxicity |
| WO2009102995A1 (en) | 2008-02-15 | 2009-08-20 | Whitehead Institute For Biomedical Research | Yeast cells expressing tar dna-binding protein 43 and uses therefor |
| US20100021437A1 (en) | 2008-04-07 | 2010-01-28 | The McLean Hospital Corporation Whitehead Institute for Biomedical Research | Neural stem cells derived from induced pluripotent stem cells |
| WO2010042669A2 (en) * | 2008-10-07 | 2010-04-15 | Ipierian, Inc. | Co-culture compositions and methods |
| US8865411B2 (en) | 2009-03-26 | 2014-10-21 | National Institutes Of Health (Nih) | Methods of identifying modulators of TDP-43 mediated cellular toxicity |
| WO2010117464A1 (en) | 2009-04-09 | 2010-10-14 | Sangamo Biosciences, Inc. | Targeted integration into stem cells |
| US20110088107A1 (en) | 2009-04-24 | 2011-04-14 | Yaqub Hanna | Compositions and methods for deriving or culturing pluripotent cells |
| US9677079B2 (en) | 2010-01-12 | 2017-06-13 | Whitehead Insititute for Biomedical Research | Yeast cells expressing amyloid beta and uses therefor |
| EP3594333B1 (en) | 2010-02-08 | 2023-11-01 | Sangamo Therapeutics, Inc. | Engineered cleavage half-domains |
| CA2796464C (en) | 2010-04-16 | 2021-08-03 | Immune Disease Institute, Inc. | Sustained polypeptide expression from synthetic, modified rnas and uses thereof |
| WO2011142832A2 (en) | 2010-05-13 | 2011-11-17 | Whitehead Institute For Biomedical Research | Stem cells derived under low oxygen conditions |
| US9267123B2 (en) * | 2011-01-05 | 2016-02-23 | Sangamo Biosciences, Inc. | Methods and compositions for gene correction |
| WO2012112737A2 (en) | 2011-02-16 | 2012-08-23 | The Regents Of The University Of California | Alzheimer's disease cellular model for diagnostic and therapeutic development |
| GB201103631D0 (en) | 2011-03-03 | 2011-04-13 | Univ Leeds | Identification of candidate therapeutics |
| US20130045483A1 (en) | 2011-07-01 | 2013-02-21 | Whitehead Institute For Biomedical Research | Yeast cells expressing amyloid beta and uses therefor |
-
2014
- 2014-03-17 CA CA2906197A patent/CA2906197A1/en not_active Abandoned
- 2014-03-17 CN CN201480027986.XA patent/CN105247070A/zh active Pending
- 2014-03-17 EP EP20163191.8A patent/EP3736343A1/en not_active Ceased
- 2014-03-17 JP JP2016502568A patent/JP7182852B2/ja active Active
- 2014-03-17 US US14/777,013 patent/US11047848B2/en active Active
- 2014-03-17 EP EP14762590.9A patent/EP2971056A4/en not_active Ceased
- 2014-03-17 BR BR112015023533A patent/BR112015023533A2/pt not_active IP Right Cessation
- 2014-03-17 WO PCT/US2014/030838 patent/WO2014145975A2/en active Application Filing
-
2015
- 2015-09-08 IL IL241310A patent/IL241310B/en unknown
-
2016
- 2016-07-12 HK HK16108152.9A patent/HK1220232A1/zh unknown
- 2016-07-13 HK HK16108219.0A patent/HK1220233A1/zh unknown
-
2020
- 2020-02-03 JP JP2020016490A patent/JP2020103289A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US20170153226A9 (en) | 2017-06-01 |
| IL241310A0 (en) | 2015-11-30 |
| HK1220232A1 (zh) | 2017-04-28 |
| CA2906197A1 (en) | 2014-09-18 |
| EP2971056A4 (en) | 2016-11-23 |
| WO2014145975A2 (en) | 2014-09-18 |
| US11047848B2 (en) | 2021-06-29 |
| JP7182852B2 (ja) | 2022-12-05 |
| WO2014145975A3 (en) | 2014-12-31 |
| BR112015023533A2 (pt) | 2017-10-24 |
| JP2020103289A (ja) | 2020-07-09 |
| EP2971056A2 (en) | 2016-01-20 |
| EP3736343A1 (en) | 2020-11-11 |
| IL241310B (en) | 2021-12-01 |
| CN105247070A (zh) | 2016-01-13 |
| JP2016513475A (ja) | 2016-05-16 |
| US20160041149A1 (en) | 2016-02-11 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HK1220233A1 (zh) | 用於神經變性疾病的細胞性發現平台 | |
| HK1217215A1 (zh) | 用於改變細胞表型的信號傳感器多核苷酸 | |
| HK1223158A1 (zh) | 移動成像平台校準 | |
| SG11201604614UA (en) | Modular mobile inspection vehicle | |
| HK1214627A1 (zh) | 大鼠的遺傳修飾 | |
| ZA201600708B (en) | Mobile operating system | |
| GB201322602D0 (en) | Pharmaceutical compounds | |
| GB201306610D0 (en) | Pharmaceutical compounds | |
| GB2515459B (en) | Duplexers | |
| GB201320799D0 (en) | Mobile WiFi | |
| ZA201602047B (en) | Pharmaceutical compounds | |
| EP2987923A4 (en) | MOBILE COVERAGE | |
| PL2853150T3 (pl) | Mobilne urządzenie do przycinania drzew | |
| GB201312386D0 (en) | Pharmaceutical compounds | |
| SMT201800400T1 (it) | Composti pirazolopirimidinici | |
| EP2989598A4 (en) | SYSTEM FOR MOBILE BOOKINGS | |
| SI2848467T1 (sl) | Premičen oder | |
| EP3027444B8 (en) | Mobile accommodation | |
| GB2518652B (en) | Wireless geometry discovery | |
| GB2518651B (en) | Wireless geometry discovery | |
| GB201302219D0 (en) | Contraceptive compounds | |
| AP00579S1 (en) | Footsteps for vehicles | |
| AP00577S1 (en) | Footsteps for vehicles | |
| AP00578S1 (en) | Footsteps for vehicles | |
| AP00580S1 (en) | Footsteps for vehicles |