HK1205740A1 - Pyrrolotriazinone derivatives - Google Patents
Pyrrolotriazinone derivativesInfo
- Publication number
- HK1205740A1 HK1205740A1 HK15106267.6A HK15106267A HK1205740A1 HK 1205740 A1 HK1205740 A1 HK 1205740A1 HK 15106267 A HK15106267 A HK 15106267A HK 1205740 A1 HK1205740 A1 HK 1205740A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- pyrrolotriazinone derivatives
- pyrrolotriazinone
- derivatives
- Prior art date
Links
- BEBRHYJBTAMGRW-UHFFFAOYSA-N pyrrolo[3,2-d]triazin-4-one Chemical class O=C1N=NN=C2C=CN=C12 BEBRHYJBTAMGRW-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Rheumatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pain & Pain Management (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Oncology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12003445 | 2012-05-04 | ||
| PCT/EP2013/001026 WO2013164061A1 (en) | 2012-05-04 | 2013-04-06 | Pyrrolotriazinone derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1205740A1 true HK1205740A1 (en) | 2015-12-24 |
Family
ID=48050660
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK15106267.6A HK1205740A1 (en) | 2012-05-04 | 2015-07-02 | Pyrrolotriazinone derivatives |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US9174995B2 (xx) |
| EP (1) | EP2844659B1 (xx) |
| JP (1) | JP6097820B2 (xx) |
| KR (1) | KR20150006873A (xx) |
| CN (1) | CN104271580B (xx) |
| AR (1) | AR090896A1 (xx) |
| AU (1) | AU2013257018B2 (xx) |
| CA (1) | CA2872334C (xx) |
| EA (1) | EA027628B1 (xx) |
| ES (1) | ES2587939T3 (xx) |
| HK (1) | HK1205740A1 (xx) |
| HR (1) | HRP20161033T1 (xx) |
| HU (1) | HUE028325T2 (xx) |
| IL (1) | IL235414A (xx) |
| MX (1) | MX357502B (xx) |
| PL (1) | PL2844659T3 (xx) |
| PT (1) | PT2844659T (xx) |
| RS (1) | RS55062B1 (xx) |
| SG (1) | SG11201406997WA (xx) |
| SI (1) | SI2844659T1 (xx) |
| WO (1) | WO2013164061A1 (xx) |
| ZA (1) | ZA201408876B (xx) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9193689B2 (en) | 2012-03-07 | 2015-11-24 | Institute Of Cancer Research: Royal Cancer Hospital (The) | 3-aryl-5-substituted-isoquinolin-1-one compounds and their therapeutic use |
| CN105722835B (zh) | 2013-09-11 | 2018-07-31 | 癌症研究协会:皇家癌症医院 | 3-芳基-5-取代的-异喹啉-1-酮化合物及它们的疗法应用 |
| HUE037606T2 (hu) * | 2013-12-23 | 2018-09-28 | Merck Patent Gmbh | Imidazopirazinon-származékok |
| UY36060A (es) | 2014-04-02 | 2015-10-30 | Bayer Pharma AG | Compuestos de azol sustituidos con amida |
| US9856262B2 (en) * | 2014-04-10 | 2018-01-02 | Hubei Bio-Pharmaceutical Industrial Technological Institute Inc. | Analogues of 4H-pyrazolo[1,5-a] benzimidazole compound as PARP inhibitors |
| KR20160007347A (ko) * | 2014-07-11 | 2016-01-20 | 에스티팜 주식회사 | 신규한 이미다조트리아지논 또는 이미다조피라지논 유도체, 및 이들의 용도 |
| KR101775356B1 (ko) * | 2015-07-06 | 2017-09-06 | 재단법인 아산사회복지재단 | Parp 및 탄키라제 동시 저해제에 대한 감수성 결정 방법 |
| CA3038280A1 (en) * | 2015-09-30 | 2017-04-06 | Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. - Generalverwaltung | Heteroaryl derivatives as sepiapterin reductase inhibitors |
| WO2017055313A1 (en) | 2015-10-01 | 2017-04-06 | Bayer Pharma Aktiengesellschaft | Amido-substituted azole compounds |
| WO2017055316A1 (en) | 2015-10-01 | 2017-04-06 | Bayer Pharma Aktiengesellschaft | Amido-substituted azole compounds |
| EP3377495B1 (en) | 2015-11-16 | 2022-03-16 | Topadur Pharma AG | 2-phenyl-3,4-dihydropyrrolo[2,1-f] [1,2,4]triazinone derivatives as phosphodiesterase inhibitors and uses thereof |
| WO2017156350A1 (en) | 2016-03-09 | 2017-09-14 | K-Gen, Inc. | Methods of cancer treatment |
| WO2018078009A1 (en) | 2016-10-29 | 2018-05-03 | Bayer Pharma Aktiengesellschaft | Amido-substituted cyclohexane derivatives |
| WO2018078005A1 (en) | 2016-10-29 | 2018-05-03 | Bayer Pharma Aktiengesellschaft | Amido-substituted azaspiro derivatives as tankyrase inhibitors |
| WO2018087126A1 (en) | 2016-11-09 | 2018-05-17 | Bayer Pharma Aktiengesellschaft | Amido-substituted cyclohexane derivatives as inhibitors of tankyrase |
| CN109180702B (zh) * | 2018-10-29 | 2021-11-30 | 四川大学 | 一种噻吩并嘧啶酮化合物及其用途 |
| CN111961058B (zh) * | 2020-08-03 | 2022-12-16 | 天津全和诚科技有限责任公司 | 4-氨基-吡咯并三嗪衍生物及其制备方法和用途 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9624482D0 (en) | 1995-12-18 | 1997-01-15 | Zeneca Phaema S A | Chemical compounds |
| ATE237596T1 (de) | 1996-02-13 | 2003-05-15 | Astrazeneca Ab | Chinazolinderivate und deren verwendung als vegf hemmer |
| PT885198E (pt) | 1996-03-05 | 2002-06-28 | Astrazeneca Ab | Derivados de 4-anilinoquinazolina |
| GB9718972D0 (en) | 1996-09-25 | 1997-11-12 | Zeneca Ltd | Chemical compounds |
| GB9714249D0 (en) | 1997-07-08 | 1997-09-10 | Angiogene Pharm Ltd | Vascular damaging agents |
| GB9900334D0 (en) | 1999-01-07 | 1999-02-24 | Angiogene Pharm Ltd | Tricylic vascular damaging agents |
| GB9900752D0 (en) | 1999-01-15 | 1999-03-03 | Angiogene Pharm Ltd | Benzimidazole vascular damaging agents |
| AU2001258628A1 (en) | 2000-05-31 | 2001-12-11 | Astrazeneca Ab | Indole derivatives with vascular damaging activity |
| RU2003103603A (ru) | 2000-07-07 | 2004-08-20 | Энджиоджен Фармасьютикалз Лимитед (Gb) | Производные колхинола в качестве ингибиторов ангиогенеза |
| CN1255391C (zh) | 2000-07-07 | 2006-05-10 | 安吉奥金尼药品有限公司 | 作为血管破坏剂的colchinol衍生物 |
| JP2006521398A (ja) | 2003-03-28 | 2006-09-21 | サイオス・インコーポレーテツド | ＴＧＦβの二−環式ピリミジン阻害剤 |
| CN100594903C (zh) | 2004-09-30 | 2010-03-24 | 泰博特克药品有限公司 | Hcv抑制性双环嘧啶 |
| WO2008092861A1 (en) | 2007-01-30 | 2008-08-07 | Janssen Pharmaceutica N.V. | Bicyclic derivatives as ep4 agonists |
| CA2678248C (en) | 2007-03-08 | 2016-06-28 | Janssen Pharmaceutica Nv | Quinolinone derivatives as parp and tank inhibitors |
| EP2134716A1 (en) * | 2007-04-18 | 2009-12-23 | Bristol-Myers Squibb Company | Pyrrolotriazine kinase inhibitors |
-
2013
- 2013-04-06 SI SI201330275A patent/SI2844659T1/sl unknown
- 2013-04-06 KR KR1020147033753A patent/KR20150006873A/ko not_active Ceased
- 2013-04-06 CN CN201380023419.2A patent/CN104271580B/zh not_active Expired - Fee Related
- 2013-04-06 RS RS20160696A patent/RS55062B1/sr unknown
- 2013-04-06 US US14/398,212 patent/US9174995B2/en not_active Expired - Fee Related
- 2013-04-06 MX MX2014013090A patent/MX357502B/es active IP Right Grant
- 2013-04-06 EA EA201401212A patent/EA027628B1/ru not_active IP Right Cessation
- 2013-04-06 ES ES13714859.9T patent/ES2587939T3/es active Active
- 2013-04-06 HU HUE13714859A patent/HUE028325T2/en unknown
- 2013-04-06 JP JP2015509321A patent/JP6097820B2/ja not_active Expired - Fee Related
- 2013-04-06 EP EP13714859.9A patent/EP2844659B1/en active Active
- 2013-04-06 WO PCT/EP2013/001026 patent/WO2013164061A1/en active Application Filing
- 2013-04-06 PL PL13714859.9T patent/PL2844659T3/pl unknown
- 2013-04-06 PT PT137148599T patent/PT2844659T/pt unknown
- 2013-04-06 SG SG11201406997WA patent/SG11201406997WA/en unknown
- 2013-04-06 AU AU2013257018A patent/AU2013257018B2/en not_active Ceased
- 2013-04-06 CA CA2872334A patent/CA2872334C/en active Active
- 2013-04-30 AR ARP130101468A patent/AR090896A1/es unknown
-
2014
- 2014-10-30 IL IL235414A patent/IL235414A/en active IP Right Grant
- 2014-12-03 ZA ZA2014/08876A patent/ZA201408876B/en unknown
-
2015
- 2015-07-02 HK HK15106267.6A patent/HK1205740A1/xx not_active IP Right Cessation
-
2016
- 2016-08-17 HR HRP20161033TT patent/HRP20161033T1/hr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2872334C (en) | 2020-06-30 |
| ZA201408876B (en) | 2017-06-28 |
| AU2013257018B2 (en) | 2017-02-16 |
| CN104271580B (zh) | 2017-02-22 |
| SG11201406997WA (en) | 2014-11-27 |
| CA2872334A1 (en) | 2013-11-07 |
| EP2844659B1 (en) | 2016-05-25 |
| IL235414A (en) | 2017-11-30 |
| JP6097820B2 (ja) | 2017-03-15 |
| HRP20161033T1 (hr) | 2016-10-21 |
| RS55062B1 (sr) | 2016-12-30 |
| CN104271580A (zh) | 2015-01-07 |
| EA027628B1 (ru) | 2017-08-31 |
| MX2014013090A (es) | 2014-12-08 |
| US20150133453A1 (en) | 2015-05-14 |
| JP2015515961A (ja) | 2015-06-04 |
| AU2013257018A1 (en) | 2014-12-18 |
| EP2844659A1 (en) | 2015-03-11 |
| SI2844659T1 (sl) | 2016-10-28 |
| PL2844659T3 (pl) | 2016-11-30 |
| HUE028325T2 (en) | 2016-12-28 |
| ES2587939T3 (es) | 2016-10-27 |
| AR090896A1 (es) | 2014-12-17 |
| WO2013164061A8 (en) | 2014-11-06 |
| EA201401212A1 (ru) | 2015-08-31 |
| KR20150006873A (ko) | 2015-01-19 |
| WO2013164061A1 (en) | 2013-11-07 |
| PT2844659T (pt) | 2016-08-31 |
| US9174995B2 (en) | 2015-11-03 |
| MX357502B (es) | 2018-07-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20210402 |