HK1140761A1 - Indole derivatives as s1p1 receptor agonists - Google Patents

Indole derivatives as s1p1 receptor agonists

Info

Publication number: HK1140761A1
Authority: HK; Hong Kong
Prior art keywords: receptor agonists; indole derivatives; indole; derivatives; agonists
Prior art date: 2006-12-21

Application number

HK10107189.4A

Other languages

English (en)

Inventor

Mahmood Ahmed

James Myatt

David Norton

Dean Andrew Rivers

Original Assignee

Glaxo Group Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-12-21

Filing date

2009-10-06

Publication date

2010-10-22

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39283563&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1140761(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2006-12-21 Priority claimed from GB0625647A external-priority patent/GB0625647D0/en

2007-04-19 Priority claimed from GB0707615A external-priority patent/GB0707615D0/en

2009-10-06 Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd

2010-10-22 Publication of HK1140761A1 publication Critical patent/HK1140761A1/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
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- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
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- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
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- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Immunology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Diabetes (AREA)
Pulmonology (AREA)
Oncology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Virology (AREA)
Communicable Diseases (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Emergency Medicine (AREA)
Endocrinology (AREA)
Hematology (AREA)
Obesity (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Transplantation (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Dermatology (AREA)

HK10107189.4A 2006-12-21 2009-10-06 Indole derivatives as s1p1 receptor agonists HK1140761A1 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GB0625647A GB0625647D0 (en)	2006-12-21	2006-12-21	Compounds
GB0707615A GB0707615D0 (en)	2007-04-19	2007-04-19	Compounds
HK09109205.3A HK1130255A1 (en)	2006-12-21	2009-10-06	Indole derivatives as s1p1 receptor agonists

Publications (1)

Publication Number	Publication Date
HK1140761A1 true HK1140761A1 (en)	2010-10-22

Family

ID=39283563

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
HK09109205.3A HK1130255A1 (en)	2006-12-21	2009-10-06	Indole derivatives as s1p1 receptor agonists
HK10107189.4A HK1140761A1 (en)	2006-12-21	2009-10-06	Indole derivatives as s1p1 receptor agonists

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
HK09109205.3A HK1130255A1 (en)	2006-12-21	2009-10-06	Indole derivatives as s1p1 receptor agonists

Country Status (33)

Country	Link
US (1)	US8101775B2 (xx)
EP (2)	EP2206710B1 (xx)
JP (1)	JP5309034B2 (xx)
KR (1)	KR101495927B1 (xx)
CN (1)	CN103012390B (xx)
AR (1)	AR064452A1 (xx)
AT (1)	ATE509927T1 (xx)
AU (1)	AU2007336224B2 (xx)
BR (1)	BRPI0721127A2 (xx)
CA (1)	CA2673468C (xx)
CL (1)	CL2007003755A1 (xx)
CR (2)	CR10922A (xx)
CY (2)	CY1111702T1 (xx)
DK (2)	DK2091949T3 (xx)
DO (1)	DOP2009000133A (xx)
EA (1)	EA017406B1 (xx)
ES (1)	ES2389879T3 (xx)
HK (2)	HK1130255A1 (xx)
HR (2)	HRP20110456T1 (xx)
IL (1)	IL199187A (xx)
JO (1)	JO2701B1 (xx)
MA (1)	MA30999B1 (xx)
MX (1)	MX2009006882A (xx)
MY (2)	MY148470A (xx)
NO (1)	NO20092385L (xx)
NZ (1)	NZ577387A (xx)
PE (2)	PE20081398A1 (xx)
PL (2)	PL2206710T3 (xx)
PT (2)	PT2091949E (xx)
SG (1)	SG177914A1 (xx)
SI (2)	SI2091949T1 (xx)
TW (1)	TWI393564B (xx)
WO (1)	WO2008074821A1 (xx)

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Publication number	Publication date
NZ577387A (en)	2012-01-12
CY1111702T1 (el)	2015-10-07
EP2091949B1 (en)	2011-05-18
PL2091949T3 (pl)	2011-10-31
EA200970612A1 (ru)	2009-10-30
JP5309034B2 (ja)	2013-10-09
KR20090092290A (ko)	2009-08-31
EP2091949A1 (en)	2009-08-26
MA30999B1 (fr)	2009-12-01
CA2673468A1 (en)	2008-06-26
HRP20110456T1 (hr)	2011-07-31
EP2206710B1 (en)	2012-07-04
EA017406B1 (ru)	2012-12-28
IL199187A0 (en)	2010-03-28
NO20092385L (no)	2009-08-24
PE20121076A1 (es)	2012-09-05
MY148470A (en)	2013-04-30
HK1130255A1 (en)	2009-12-24
PT2091949E (pt)	2011-07-13
US20100113796A1 (en)	2010-05-06
TW200843736A (en)	2008-11-16
HRP20120685T1 (hr)	2012-09-30
KR101495927B1 (ko)	2015-02-25
PT2206710E (pt)	2012-09-10
AR064452A1 (es)	2009-04-01
CR20140316A (es)	2014-08-20
TWI393564B (zh)	2013-04-21
MX2009006882A (es)	2009-07-03
JP2010513397A (ja)	2010-04-30
SI2206710T1 (sl)	2012-10-30
ES2389879T3 (es)	2012-11-02
JO2701B1 (en)	2013-03-03
CL2007003755A1 (es)	2008-08-22
SI2091949T1 (sl)	2011-08-31
IL199187A (en)	2015-04-30
PE20081398A1 (es)	2008-11-19
DK2206710T3 (da)	2012-08-27
WO2008074821A1 (en)	2008-06-26
MY156822A (en)	2016-03-31
BRPI0721127A2 (pt)	2014-03-11
EP2206710A1 (en)	2010-07-14
SG177914A1 (en)	2012-02-28
AU2007336224B2 (en)	2013-01-10
CR10922A (es)	2009-08-12
US8101775B2 (en)	2012-01-24
DOP2009000133A (es)	2009-08-15
DK2091949T3 (da)	2011-07-18
PL2206710T3 (pl)	2012-11-30
AU2007336224A1 (en)	2008-06-26
CN103012390B (zh)	2015-08-26
ATE509927T1 (de)	2011-06-15
CA2673468C (en)	2015-06-02
CY1113131T1 (el)	2016-04-13
CN103012390A (zh)	2013-04-03

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ZA200709086B (en)	2008-12-31	Novel thiophene derivatives as sphingosine-1-phosphate-1 receptor agonists
PT2003132E (pt)	2014-05-26	Derivados de oxadiazole como agonistas dos s1p1
EP2049520A4 (en)	2011-01-05	indole compounds
HK1149762A1 (en)	2011-10-14	Substituted indole derivatives
HK1110980A1 (en)	2008-07-25	Benzimidazole-carboxamide compounds as 5-ht4 receptor agonists
ZA200905265B (en)	2010-04-28	Indole derivatives
ZA200900843B (en)	2010-03-31	Indole compounds
ZA200903829B (en)	2010-04-28	Indole derivatives as S1P1 receptor agonists
ZA200709829B (en)	2008-11-26	Benzimidazole-carboxamide compounds as 5-HT4 receptor agonists
AU2008903336A0 (en)	2008-07-17	TPOR Receptor Agonists

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