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HK1139390A1 - Cycloalkylamine substituted isoquinolone derivatives - Google Patents

Cycloalkylamine substituted isoquinolone derivatives

Info

Publication number
HK1139390A1
HK1139390A1 HK10105359.2A HK10105359A HK1139390A1 HK 1139390 A1 HK1139390 A1 HK 1139390A1 HK 10105359 A HK10105359 A HK 10105359A HK 1139390 A1 HK1139390 A1 HK 1139390A1
Authority
HK
Hong Kong
Prior art keywords
isoquinolone derivatives
substituted isoquinolone
cycloalkylamine
cycloalkylamine substituted
derivatives
Prior art date
Application number
HK10105359.2A
Other languages
English (en)
Inventor
Oliver Plettenburg
Armin Hofmeister
Katrin Lorenz
Joachim Brendel
Matthias Loehn
John Weston
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38565513&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1139390(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of HK1139390A1 publication Critical patent/HK1139390A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/24—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/472—Non-condensed isoquinolines, e.g. papaverine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
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    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Immunology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Endocrinology (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Reproductive Health (AREA)
  • Obesity (AREA)
  • Rheumatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Pulmonology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Hospice & Palliative Care (AREA)
  • Virology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Epidemiology (AREA)
HK10105359.2A 2006-12-27 2010-06-01 Cycloalkylamine substituted isoquinolone derivatives HK1139390A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06026899 2006-12-27
PCT/EP2007/011164 WO2008077551A1 (en) 2006-12-27 2007-12-19 Cycloalkylamine substituted isoquinolone derivatives

Publications (1)

Publication Number Publication Date
HK1139390A1 true HK1139390A1 (en) 2010-09-17

Family

ID=38565513

Family Applications (1)

Application Number Title Priority Date Filing Date
HK10105359.2A HK1139390A1 (en) 2006-12-27 2010-06-01 Cycloalkylamine substituted isoquinolone derivatives

Country Status (31)

Country Link
US (1) US8742116B2 (no)
EP (1) EP2125745B1 (no)
JP (1) JP5405314B2 (no)
KR (1) KR101474228B1 (no)
CN (1) CN101595094B (no)
AR (1) AR064492A1 (no)
AU (1) AU2007338407B2 (no)
BR (1) BRPI0722064A2 (no)
CA (1) CA2673917C (no)
CL (1) CL2007003821A1 (no)
CO (1) CO6210726A2 (no)
CR (1) CR10813A (no)
DO (1) DOP2009000164A (no)
EC (1) ECSP099467A (no)
ES (1) ES2625266T3 (no)
GT (1) GT200900179A (no)
HK (1) HK1139390A1 (no)
IL (1) IL199540A (no)
MA (1) MA31075B1 (no)
MX (1) MX2009005966A (no)
MY (1) MY155009A (no)
NI (1) NI200900108A (no)
NO (1) NO20092422L (no)
NZ (1) NZ577980A (no)
RU (1) RU2457203C2 (no)
SV (1) SV2009003318A (no)
TN (1) TN2009000269A1 (no)
TW (1) TWI434689B (no)
UY (1) UY30843A1 (no)
WO (1) WO2008077551A1 (no)
ZA (1) ZA200903551B (no)

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TWI512335B (zh) 2003-11-20 2015-12-11 尼康股份有限公司 光束變換元件、光學照明裝置、曝光裝置、以及曝光方法
TWI511182B (zh) 2004-02-06 2015-12-01 尼康股份有限公司 光學照明裝置、曝光裝置、曝光方法以及元件製造方法
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EP2303846B1 (en) * 2008-06-24 2015-04-29 Sanofi Substituted isoquinolines and isoquinolinones as rho kinase inhibitors
AU2009262509B2 (en) * 2008-06-24 2014-01-30 Sanofi Bi-and polycyclic substituted isoquinoline and isoquinoline derivatives as Rho kinase inhibitors
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US8450344B2 (en) 2008-07-25 2013-05-28 Aerie Pharmaceuticals, Inc. Beta- and gamma-amino-isoquinoline amide compounds and substituted benzamide compounds
ES2553827T3 (es) 2009-05-01 2015-12-14 Aerie Pharmaceuticals, Inc. Inhibidores de mecanismo doble para el tratamiento de enfermedad
WO2014144781A1 (en) 2013-03-15 2014-09-18 Aerie Pharmaceuticals, Inc. Combination therapy
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