HK1134294A1 - Thiophene derivatives as s1p1/edg1 receptor agonists - Google Patents

Thiophene derivatives as s1p1/edg1 receptor agonists

Info

Publication number: HK1134294A1
Authority: HK; Hong Kong
Prior art keywords: receptor agonists; thiophene derivatives; edg1 receptor; edg1; thiophene
Prior art date: 2006-09-07

Application number

HK10102436.6A

Other languages

English (en)

Inventor

Martin Bolli

David Lehmann

Boris Mathys

Claus Mueller

Oliver Nayler

Beat Steiner

Joerg Velker

Original Assignee

Actelion Pharmaceuticals Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-09-07

Filing date

2010-03-08

Publication date

2010-04-23

2010-03-08 Application filed by Actelion Pharmaceuticals Ltd filed Critical Actelion Pharmaceuticals Ltd

2010-04-23 Publication of HK1134294A1 publication Critical patent/HK1134294A1/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
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- A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
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- A—HUMAN NECESSITIES
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- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Immunology (AREA)
Diabetes (AREA)
Pulmonology (AREA)
Dermatology (AREA)
Urology & Nephrology (AREA)
Rheumatology (AREA)
Endocrinology (AREA)
Cardiology (AREA)
Neurosurgery (AREA)
Vascular Medicine (AREA)
Oncology (AREA)
Transplantation (AREA)
Obesity (AREA)
Pain & Pain Management (AREA)
Hematology (AREA)
Ophthalmology & Optometry (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Heart & Thoracic Surgery (AREA)
Emergency Medicine (AREA)
Otolaryngology (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

HK10102436.6A 2006-09-07 2010-03-08 Thiophene derivatives as s1p1/edg1 receptor agonists HK1134294A1 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
IB2006053150		2006-09-07
PCT/IB2007/052742 WO2008029306A2 (en)	2006-09-07	2007-07-10	Thiophene derivatives as s1p1/edg1 receptor agonists

Publications (1)

Publication Number	Publication Date
HK1134294A1 true HK1134294A1 (en)	2010-04-23

Family

ID=38969819

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HK10102436.6A HK1134294A1 (en)	2006-09-07	2010-03-08	Thiophene derivatives as s1p1/edg1 receptor agonists

Country Status (28)

Country	Link
US (1)	US8133910B2 (xx)
EP (1)	EP2069322B1 (xx)
JP (1)	JP5250555B2 (xx)
KR (1)	KR101409560B1 (xx)
CN (1)	CN101528726B (xx)
AR (1)	AR061841A1 (xx)
AU (1)	AU2007293113B2 (xx)
BR (1)	BRPI0716482A2 (xx)
CA (1)	CA2661102C (xx)
CL (1)	CL2007001997A1 (xx)
CY (1)	CY1113267T1 (xx)
DK (1)	DK2069322T3 (xx)
ES (1)	ES2393002T3 (xx)
HK (1)	HK1134294A1 (xx)
HR (1)	HRP20120962T1 (xx)
IL (1)	IL197395A (xx)
MA (1)	MA30765B1 (xx)
MX (1)	MX2009002227A (xx)
MY (1)	MY149869A (xx)
NO (1)	NO20091395L (xx)
NZ (1)	NZ575979A (xx)
PL (1)	PL2069322T3 (xx)
PT (1)	PT2069322E (xx)
RU (1)	RU2442783C2 (xx)
SI (1)	SI2069322T1 (xx)
TW (1)	TWI408139B (xx)
WO (1)	WO2008029306A2 (xx)
ZA (1)	ZA200902391B (xx)

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JP2010502693A (ja)	2010-01-28
IL197395A0 (en)	2009-12-24
JP5250555B2 (ja)	2013-07-31
CN101528726B (zh)	2012-11-14
CY1113267T1 (el)	2016-04-13
CA2661102A1 (en)	2008-03-13
BRPI0716482A2 (pt)	2013-03-12
MA30765B1 (fr)	2009-10-01
NZ575979A (en)	2012-02-24
PL2069322T3 (pl)	2013-02-28
NO20091395L (no)	2009-04-06
MY149869A (en)	2013-10-31
WO2008029306A2 (en)	2008-03-13
ZA200902391B (en)	2015-08-26
AU2007293113B2 (en)	2013-02-14
PT2069322E (pt)	2012-11-21
DK2069322T3 (da)	2012-11-05
RU2009112536A (ru)	2010-10-20
AR061841A1 (es)	2008-09-24
KR101409560B1 (ko)	2014-06-19
MX2009002227A (es)	2009-03-16
SI2069322T1 (sl)	2012-12-31
WO2008029306A3 (en)	2008-05-15
EP2069322B1 (en)	2012-09-12
EP2069322A2 (en)	2009-06-17
AU2007293113A1 (en)	2008-03-13
TWI408139B (zh)	2013-09-11
US20100048648A1 (en)	2010-02-25
HRP20120962T1 (hr)	2012-12-31
IL197395A (en)	2014-06-30
CA2661102C (en)	2014-10-14
ES2393002T3 (es)	2012-12-17
KR20090059144A (ko)	2009-06-10
CL2007001997A1 (es)	2008-03-07
US8133910B2 (en)	2012-03-13
RU2442783C2 (ru)	2012-02-20
CN101528726A (zh)	2009-09-09
TW200813044A (en)	2008-03-16

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