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HK1055749A1 - Process for the synthesis of an lhrh peptide - Google Patents

Process for the synthesis of an lhrh peptide Download PDF

Info

Publication number
HK1055749A1
HK1055749A1 HK03107934A HK03107934A HK1055749A1 HK 1055749 A1 HK1055749 A1 HK 1055749A1 HK 03107934 A HK03107934 A HK 03107934A HK 03107934 A HK03107934 A HK 03107934A HK 1055749 A1 HK1055749 A1 HK 1055749A1
Authority
HK
Hong Kong
Prior art keywords
boc
resin
peptide
gly
yield
Prior art date
Application number
HK03107934A
Other languages
German (de)
English (en)
French (fr)
Chinese (zh)
Other versions
HK1055749B (en
Inventor
Steven Allen Jackson
Original Assignee
Ipsen Manufacturing Ireland Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ipsen Manufacturing Ireland Limited filed Critical Ipsen Manufacturing Ireland Limited
Publication of HK1055749A1 publication Critical patent/HK1055749A1/en
Publication of HK1055749B publication Critical patent/HK1055749B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C07K1/061General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
    • C07K1/068General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups for heterocyclic side chains
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/23Luteinising hormone-releasing hormone [LHRH]; Related peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HK03107934.1A 2000-12-22 2001-12-19 Process for the synthesis of an lhrh peptide HK1055749B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IE2000/1079 2000-12-22
IE20001079 2000-12-22
PCT/IE2001/000159 WO2002051861A2 (en) 2000-12-22 2001-12-19 Process for the synthesis of a peptide having a tryptophan residue

Publications (2)

Publication Number Publication Date
HK1055749A1 true HK1055749A1 (en) 2004-01-21
HK1055749B HK1055749B (en) 2006-11-17

Family

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Also Published As

Publication number Publication date
JP2004516330A (ja) 2004-06-03
US7122628B2 (en) 2006-10-17
KR100591832B1 (ko) 2006-06-20
AU2002222439B2 (en) 2005-04-07
KR20030081355A (ko) 2003-10-17
US20040077827A1 (en) 2004-04-22
ZA200304809B (en) 2004-04-20
NO20032852L (no) 2003-08-22
PL361993A1 (en) 2004-10-18
WO2002051861A3 (en) 2002-10-10
RU2003122779A (ru) 2005-02-20
IES20011090A2 (en) 2002-12-30
IL156258A0 (en) 2004-01-04
ES2266104T3 (es) 2007-03-01
HU230601B1 (hu) 2017-02-28
CA2432708A1 (en) 2002-07-04
PT1343808E (pt) 2007-01-31
WO2002051861A2 (en) 2002-07-04
NO20032852D0 (no) 2003-06-20
EP1343808A2 (en) 2003-09-17
HU229701B1 (en) 2014-05-28
CZ299141B6 (cs) 2008-04-30
JP4064817B2 (ja) 2008-03-19
IL156258A (en) 2008-06-05
DK1343808T3 (da) 2006-12-11
CA2432708C (en) 2011-07-12
MXPA03005678A (es) 2003-10-06
CN1481389A (zh) 2004-03-10
CN101003563A (zh) 2007-07-25
NZ526990A (en) 2005-04-29
HUP0302633A3 (en) 2008-04-28
PL205949B1 (pl) 2010-06-30
DE60123115D1 (de) 2006-10-26
ATE339442T1 (de) 2006-10-15
HUP0302633A2 (hu) 2003-12-29
BR0116447A (pt) 2003-10-07
DE60123115T2 (de) 2007-03-29
RU2276156C2 (ru) 2006-05-10
CZ20031634A3 (cs) 2003-09-17
EP1343808B1 (en) 2006-09-13
AU2002222439C1 (en) 2005-10-27
NO325038B1 (no) 2008-01-21
HUP1400157A2 (en) 2003-12-29
BR0116447B1 (pt) 2014-04-29

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Legal Events

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CHPA Change of a particular in the register (except of change of ownership)
PE Patent expired

Effective date: 20211218