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HK1049440A1 - 含有一種抗腫瘤的蒽環素糖苷之可注射的立即可用型溶液 - Google Patents

含有一種抗腫瘤的蒽環素糖苷之可注射的立即可用型溶液 Download PDF

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Publication number
HK1049440A1
HK1049440A1 HK03101548.2A HK03101548A HK1049440A1 HK 1049440 A1 HK1049440 A1 HK 1049440A1 HK 03101548 A HK03101548 A HK 03101548A HK 1049440 A1 HK1049440 A1 HK 1049440A1
Authority
HK
Hong Kong
Prior art keywords
hcl
doxorubicin
solution
stability
physiologically acceptable
Prior art date
Application number
HK03101548.2A
Other languages
English (en)
Inventor
Gatti Gaetano
Oldani Diego
Bottoni Giuseppe
Confalonieri Carlo
Gambini Luciano
De Ponti Roberto
Original Assignee
Pharmacia Italia S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26291656&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1049440(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB868629193A external-priority patent/GB8629193D0/en
Application filed by Pharmacia Italia S.P.A. filed Critical Pharmacia Italia S.P.A.
Publication of HK1049440A1 publication Critical patent/HK1049440A1/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HK03101548.2A 1986-12-05 1998-11-30 含有一種抗腫瘤的蒽環素糖苷之可注射的立即可用型溶液 HK1049440A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB8629193 1986-12-05
GB868629193A GB8629193D0 (en) 1986-12-05 1986-12-05 Injectable ready-to-use solutions
US6465387A 1987-06-22 1987-06-22

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
HK98112442.2A Addition HK1011288B (zh) 1986-12-05 1998-11-30 含有羅紅莓素(doxorubicin)之可注射的立即可用型溶液

Related Child Applications (1)

Application Number Title Priority Date Filing Date
HK98112442.2A Division HK1011288B (zh) 1986-12-05 1998-11-30 含有羅紅莓素(doxorubicin)之可注射的立即可用型溶液

Publications (1)

Publication Number Publication Date
HK1049440A1 true HK1049440A1 (zh) 2003-05-16

Family

ID=26291656

Family Applications (2)

Application Number Title Priority Date Filing Date
HK395/91A HK39591A (en) 1986-12-05 1991-05-23 Injectable ready-to-use solutions containing an antitumor anthracycline glycoside
HK03101548.2A HK1049440A1 (zh) 1986-12-05 1998-11-30 含有一種抗腫瘤的蒽環素糖苷之可注射的立即可用型溶液

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HK395/91A HK39591A (en) 1986-12-05 1991-05-23 Injectable ready-to-use solutions containing an antitumor anthracycline glycoside

Country Status (22)

Country Link
EP (4) EP0438183B1 (zh)
JP (1) JP2621255B2 (zh)
KR (2) KR960007861B1 (zh)
CN (1) CN1058391C (zh)
AT (2) ATE240108T1 (zh)
AU (1) AU632036B2 (zh)
BE (1) BE1000540A5 (zh)
CH (1) CH680494A5 (zh)
DE (4) DE3751589T2 (zh)
DK (1) DK175815B1 (zh)
ES (3) ES2198424T3 (zh)
FI (1) FI91710C (zh)
FR (1) FR2607702B1 (zh)
GB (1) GB2200047B (zh)
GR (2) GR871846B (zh)
HK (2) HK39591A (zh)
IT (1) IT1226072B (zh)
NL (1) NL8702914A (zh)
NO (1) NO175802C (zh)
PT (1) PT86285B (zh)
SE (1) SE512881C2 (zh)
SG (1) SG36591G (zh)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8519452D0 (en) * 1985-08-02 1985-09-11 Erba Farmitalia Injectable solutions
DE10300323A1 (de) * 2003-01-09 2004-10-14 Baxter Healthcare S.A. Sicherheitsbehälter mit erhöhter Bruch und Splitterfestigkeit sowie kontaminationsfreier Außenfläche für biologisch aktive Substanzen und Verfahren zu deren Herstellung
CN1525856A (zh) * 2001-05-11 2004-09-01 三菱制药株式会社 含吡唑啉酮衍生物的稳定的高浓度注射剂
WO2006085336A2 (en) * 2005-02-11 2006-08-17 Dabur Pharma Limited Stabilized anthracycline glycoside pharmaceutical compositions
EP1814525A2 (en) * 2005-05-11 2007-08-08 Sicor Inc. Stable lyophilized anthracycline glycosides
US8227430B2 (en) * 2007-09-04 2012-07-24 Meiji Seika Pharma Co., Ltd Injectable, injection solution, and injection kit preparation
EP2174651A1 (en) * 2008-10-09 2010-04-14 Charité-Universitätsmedizin Berlin (Charité) A polymer-free hydrogel
CN102614118B (zh) * 2012-03-15 2014-04-30 北京协和药厂 注射用盐酸表柔比星制剂的制备方法及制剂
CN111617030B (zh) * 2020-05-22 2021-09-07 广东药科大学 壳寡糖口服液及其在制备减肥药物中的应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4177264A (en) * 1977-10-17 1979-12-04 Sri International N-benzyl anthracyclines
GB2007645B (en) * 1977-10-17 1982-05-12 Stanford Res Inst Int Benzyl anthracyclines and pharmaceutical compositions containing them
GB2187311B (en) * 1984-07-27 1988-02-10 Ae Plc Automatic vehicle speed control system
GB8426672D0 (en) * 1984-10-22 1984-11-28 Erba Farmitalia Pharmaceutical compositions
GB8519452D0 (en) * 1985-08-02 1985-09-11 Erba Farmitalia Injectable solutions
JPH0655667A (ja) * 1992-08-06 1994-03-01 Nippon Zeon Co Ltd 複合成形体

Also Published As

Publication number Publication date
NL8702914A (nl) 1988-07-01
EP0273603A3 (en) 1988-07-20
EP1283044A2 (en) 2003-02-12
AU8205987A (en) 1988-06-09
EP0273603B1 (en) 1992-03-11
DK175815B1 (da) 2005-03-07
FI875340L (fi) 1988-06-06
EP0438183A1 (en) 1991-07-24
NO875055L (no) 1988-06-06
PT86285B (pt) 1990-11-07
GB2200047B (en) 1990-11-21
SG36591G (en) 1991-06-21
GR871846B (en) 1988-04-01
GB2200047A (en) 1988-07-27
PT86285A (en) 1988-01-01
DE3752368T2 (de) 2004-02-12
ES2039460T3 (es) 1993-10-01
CN87108225A (zh) 1988-09-14
EP0659435A1 (en) 1995-06-28
FR2607702B1 (fr) 1991-08-16
EP0273603A2 (en) 1988-07-06
KR960007861B1 (ko) 1996-06-13
HK1011288A1 (zh) 1999-07-09
KR0158672B1 (en) 1998-12-01
DE3751589D1 (de) 1995-12-14
ATE129896T1 (de) 1995-11-15
SE8704849L (sv) 1988-06-06
SE512881C2 (sv) 2000-05-29
AU632036B2 (en) 1992-12-17
GR3004303T3 (zh) 1993-03-31
JPS63215633A (ja) 1988-09-08
IT1226072B (it) 1990-12-10
IT8722869A0 (it) 1987-12-03
DK635287A (da) 1988-06-06
DE3752368D1 (de) 2003-06-18
ATE240108T1 (de) 2003-05-15
CN1058391C (zh) 2000-11-15
EP0438183B1 (en) 1995-11-08
FI875340A0 (fi) 1987-12-03
KR880007086A (ko) 1988-08-26
DE3751589T2 (de) 1996-05-02
CH680494A5 (zh) 1992-09-15
ES2082023T3 (es) 1996-03-16
EP0659435B1 (en) 2003-05-14
DE3777365D1 (de) 1992-04-16
FR2607702A1 (fr) 1988-06-10
ES2198424T3 (es) 2004-02-01
GB8728313D0 (en) 1988-01-06
HK39591A (en) 1991-05-31
JP2621255B2 (ja) 1997-06-18
DE3741037A1 (de) 1988-06-09
FI91710C (fi) 1994-08-10
DK635287D0 (da) 1987-12-03
FI91710B (fi) 1994-04-29
SE8704849D0 (sv) 1987-12-03
BE1000540A5 (fr) 1989-01-24
NO875055D0 (no) 1987-12-03
EP1283044A3 (en) 2003-05-14
NO175802B (no) 1994-09-05
NO175802C (no) 1994-12-14

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