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HK1045171A1 - 進行一種液體的生物學上改良的裝置及方法 - Google Patents

進行一種液體的生物學上改良的裝置及方法 Download PDF

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Publication number
HK1045171A1
HK1045171A1 HK02106341.1A HK02106341A HK1045171A1 HK 1045171 A1 HK1045171 A1 HK 1045171A1 HK 02106341 A HK02106341 A HK 02106341A HK 1045171 A1 HK1045171 A1 HK 1045171A1
Authority
HK
Hong Kong
Prior art keywords
fluid
modification
biological modification
organ
biological
Prior art date
Application number
HK02106341.1A
Other languages
English (en)
Inventor
N. Mitrani Eduardo
Original Assignee
Yissum Research Development Company Of The Hebrew University Of Jerusalem
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yissum Research Development Company Of The Hebrew University Of Jerusalem filed Critical Yissum Research Development Company Of The Hebrew University Of Jerusalem
Publication of HK1045171A1 publication Critical patent/HK1045171A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/14—Scaffolds; Matrices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/3472—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration with treatment of the filtrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/3472—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration with treatment of the filtrate
    • A61M1/3486—Biological, chemical treatment, e.g. chemical precipitation; treatment by absorbents
    • A61M1/3489—Biological, chemical treatment, e.g. chemical precipitation; treatment by absorbents by biological cells, e.g. bioreactor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/10—Perfusion
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/067—Hepatocytes
    • C12N5/0671—Three-dimensional culture, tissue culture or organ culture; Encapsulated cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Sustainable Development (AREA)
  • Vascular Medicine (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Anesthesiology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Prostheses (AREA)
HK02106341.1A 1997-01-16 1998-01-09 進行一種液體的生物學上改良的裝置及方法 HK1045171A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US78390397A 1997-01-16 1997-01-16
US08/783,903 1997-01-16
PCT/US1998/000594 WO1999049807A2 (en) 1997-01-16 1998-01-09 A device and method for performing a biological modification of a fluid

Publications (1)

Publication Number Publication Date
HK1045171A1 true HK1045171A1 (zh) 2002-11-15

Family

ID=25130767

Family Applications (1)

Application Number Title Priority Date Filing Date
HK02106341.1A HK1045171A1 (zh) 1997-01-16 1998-01-09 進行一種液體的生物學上改良的裝置及方法

Country Status (8)

Country Link
US (1) US6372482B1 (zh)
EP (1) EP1181355A4 (zh)
JP (1) JP2002514128A (zh)
CN (1) CN1373800A (zh)
AU (1) AU748044B2 (zh)
CA (1) CA2279996A1 (zh)
HK (1) HK1045171A1 (zh)
WO (1) WO1999049807A2 (zh)

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US7759113B2 (en) * 1999-04-30 2010-07-20 The General Hospital Corporation Fabrication of tissue lamina using microfabricated two-dimensional molds
WO2004006831A2 (en) * 2002-07-12 2004-01-22 Yissum Research Development Company Of The Hebrew University Of Jerusalem Method and device for inducing biological processes by micro-organs
US20030152562A1 (en) * 2001-10-23 2003-08-14 Yissum Research Development Company Of The Hebrew University Of Jerusalem Vitro micro-organs, and uses related thereto
CA2435411A1 (en) * 1999-06-25 2001-01-04 Yissum Research Development Company Of The Hebrew University Of Jerusale M Method of inducing angiogenesis by micro-organs
US7776021B2 (en) * 2000-04-28 2010-08-17 The Charles Stark Draper Laboratory Micromachined bilayer unit for filtration of small molecules
US20020173033A1 (en) * 2001-05-17 2002-11-21 Kyle Hammerick Device and method or three-dimensional spatial localization and functional interconnection of different types of cells
US7455657B2 (en) * 2001-06-19 2008-11-25 Boston Scientific Scimed, Inc Method and apparatus to modify a fluid using a selectively permeable membrane
AU2002317458A1 (en) * 2001-07-09 2003-01-29 Medgenics, Inc. Efficient methods for assessing and validating candidate protein-based therapeutic molecules encoded by nucleic acid sequences of interest
US7468242B2 (en) 2001-11-05 2008-12-23 Medgenics, Inc. Dermal micro organs, methods and apparatuses for producing and using the same
US8088568B2 (en) 2001-11-05 2012-01-03 Medgentics, Inc. Dermal micro-organs, methods and apparatuses for producing and using the same
JP4447916B2 (ja) * 2001-11-05 2010-04-07 メドジニックス・インコーポレイテッド 微小器官処理システム及びそれを用いた微小器官の製造方法
US8501396B2 (en) 2001-11-05 2013-08-06 Medgenics Medical Israel Ltd. Dermal micro-organs, methods and apparatuses for producing and using the same
US7297540B2 (en) * 2002-01-15 2007-11-20 Yissum Research Development Company Of The Hebrew University Of Jerusalem Methods of generating tissue using devitalized, acellular scaffold matrices derived from micro-organs
ATE439039T1 (de) 2003-01-16 2009-08-15 Gen Hospital Corp Verwendung von dreidimensionalen, mikrogefertigten, mittels gewebetechnologie hergestellten systemen für pharmakologische anwendungen
US20040228829A1 (en) * 2003-03-11 2004-11-18 Roberts Craig P. Plasma detoxification system and methods of use
EP2377401B1 (en) 2003-05-01 2016-07-20 Medgenics, Inc. A genetically modified dermal micro-organ expressing erythropoietin and/or interferon
US7960166B2 (en) 2003-05-21 2011-06-14 The General Hospital Corporation Microfabricated compositions and processes for engineering tissues containing multiple cell types
US20070048732A1 (en) * 2005-08-30 2007-03-01 Hepahope, Inc. Chemosensitivity tester
US20040265997A1 (en) * 2003-06-27 2004-12-30 Park Sung-Soo Bio-artificial liver system
US8097456B2 (en) * 2003-08-18 2012-01-17 The Charles Stark Draper Laboratory Nanotopographic compositions and methods for cellular organization in tissue engineered structures
US20050244967A1 (en) * 2004-05-03 2005-11-03 Pearlman Andrew L Closed automated system for tissue based therapy
US9155749B2 (en) 2006-09-14 2015-10-13 Medgenics Medical Israel Ltd. Long lasting drug formulations
US8454948B2 (en) 2006-09-14 2013-06-04 Medgenics Medical Israel Ltd. Long lasting drug formulations
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IL196820A0 (en) 2009-02-01 2009-11-18 Yissum Res Dev Co Devitalized, acellular scaffold matrices derived from micro-organs seeded with various cells
WO2011140441A2 (en) 2010-05-06 2011-11-10 Children's Hospital Medical Center Methods and systems for converting precursor cells into intestinal tissues through directed differentiation
JP2013532152A (ja) 2010-06-15 2013-08-15 メドジェニクス・メディカル・イスラエル・リミテッド 長期持続性の医薬製剤
CN102703374B (zh) * 2012-05-07 2014-04-02 敦振毅 贴壁型细胞培养方法
CN102703319B (zh) * 2012-05-07 2014-08-06 敦振毅 贴壁型细胞培养装置及贴壁型细胞培养系统
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CN104611225A (zh) * 2015-02-16 2015-05-13 昆明市第一人民医院 体外循环灌流构建组织工程肝的生物反应器
CN106139289B (zh) * 2016-07-29 2018-06-19 武汉仝干医疗科技股份有限公司 半透膜分层一体式生物反应器
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JP2020536529A (ja) 2017-10-10 2020-12-17 チルドレンズ ホスピタル メディカル センター 食道組織および／または臓器組成物およびそれを作製する方法
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Also Published As

Publication number Publication date
JP2002514128A (ja) 2002-05-14
AU6433098A (en) 1999-10-18
EP1181355A2 (en) 2002-02-27
WO1999049807A2 (en) 1999-10-07
CN1373800A (zh) 2002-10-09
US6372482B1 (en) 2002-04-16
CA2279996A1 (en) 1998-07-16
EP1181355A4 (en) 2005-05-04
WO1999049807A3 (en) 2001-11-29
AU748044B2 (en) 2002-05-30

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