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HK1013847A1 - Gdf-1 and uog-1 proteins - Google Patents

Gdf-1 and uog-1 proteins

Info

Publication number
HK1013847A1
HK1013847A1 HK98115299A HK98115299A HK1013847A1 HK 1013847 A1 HK1013847 A1 HK 1013847A1 HK 98115299 A HK98115299 A HK 98115299A HK 98115299 A HK98115299 A HK 98115299A HK 1013847 A1 HK1013847 A1 HK 1013847A1
Authority
HK
Hong Kong
Prior art keywords
protein
gdf
uog
mammalian
proteins
Prior art date
Application number
HK98115299A
Other languages
English (en)
Inventor
Se-Jin Lee
Original Assignee
Carnegie Inst Of Washington
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Carnegie Inst Of Washington filed Critical Carnegie Inst Of Washington
Publication of HK1013847A1 publication Critical patent/HK1013847A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/51—Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
HK98115299A 1990-06-15 1998-12-24 Gdf-1 and uog-1 proteins HK1013847A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US53837290A 1990-06-15 1990-06-15
US61445290A 1990-11-16 1990-11-16
PCT/US1991/004096 WO1992000382A1 (en) 1990-06-15 1991-06-14 Gdf-1

Publications (1)

Publication Number Publication Date
HK1013847A1 true HK1013847A1 (en) 1999-12-10

Family

ID=27065793

Family Applications (1)

Application Number Title Priority Date Filing Date
HK98115299A HK1013847A1 (en) 1990-06-15 1998-12-24 Gdf-1 and uog-1 proteins

Country Status (10)

Country Link
US (2) US20040039162A1 (xx)
EP (1) EP0652951B1 (xx)
JP (1) JPH06500466A (xx)
AT (1) ATE184052T1 (xx)
AU (1) AU666291B2 (xx)
CA (1) CA2085134C (xx)
DE (1) DE69131580T2 (xx)
ES (1) ES2137931T3 (xx)
HK (1) HK1013847A1 (xx)
WO (1) WO1992000382A1 (xx)

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CA2104678C (en) 1991-03-11 2002-05-14 Charles M. Cohen Protein-induced morphogenesis
US6495513B1 (en) 1991-03-11 2002-12-17 Curis, Inc. Morphogen-enhanced survival and repair of neural cells
US6949505B1 (en) 1991-03-11 2005-09-27 Curis, Inc. Morphogen-induced dendritic growth
US7056882B2 (en) 1991-03-11 2006-06-06 Curis, Inc. Treatment to prevent loss of and/or increase bone mass in metabolic bone diseases
US5674844A (en) * 1991-03-11 1997-10-07 Creative Biomolecules, Inc. Treatment to prevent loss of and/or increase bone mass in metabolic bone diseases
ES2253736T3 (es) * 1991-08-30 2006-06-01 Curis, Inc. Tratamiento para prevenir la perdida y/o aumentar la masa osea en transtornos metabolicos del hueso.
DE69333040T3 (de) * 1992-07-31 2007-10-11 Curis, Inc., Cambridge Morphogen induzierte nerven wiederherstellung und wiedergutmachung.
EP1439190A1 (en) * 1993-01-12 2004-07-21 The Johns Hopkins University School Of Medicine Growth differentiation factor-5
US5821056A (en) 1993-01-12 1998-10-13 The Johns Hopkins University School Of Medicine Growth differentiation factor-9
AU697625B2 (en) * 1993-07-09 1998-10-15 Johns Hopkins University School Of Medicine, The Growth differentiation factor-6
EP0717633A4 (en) * 1993-07-09 1998-05-20 Univ Johns Hopkins Med GROWTH DIFFERENTIATION FACTOR-7
DK0776337T3 (da) * 1994-07-08 2005-12-12 Univ Johns Hopkins Med Vækstdifferentieringsfaktor-11
US20030167492A1 (en) 1994-07-08 2003-09-04 Johns Hopkins University School Of Medicine Transgenic non-human animals expressing a gdf-11 dominant negative polypeptide, and methods of making and using same
US5831054A (en) * 1994-07-13 1998-11-03 The Johns Hopkins University School Of Medicine Polynucleotide encoding growth differentiation factor-12
EP1364655B1 (en) 1996-03-22 2010-12-29 Stryker Corporation Method for enhancing functional recovery of motor coordination, speech or sensory perception after central nervous system ischemia or trauma
US6524802B1 (en) 1996-03-29 2003-02-25 The Johns Hopkins University School Of Medicine Methods of detecting growth differentiation factor-14
AU6267798A (en) 1997-02-07 1998-08-26 Stryker Corporation Matrix-free osteogenic devices, implants and methods of use thereof
US20010016646A1 (en) 1998-03-20 2001-08-23 David C. Rueger Osteogenic devices and methods of use thereof for repair of endochondral bone, osteochondral and chondral defects
US7041641B2 (en) 1997-03-20 2006-05-09 Stryker Corporation Osteogenic devices and methods of use thereof for repair of endochondral bone and osteochondral defects
EP2309261A1 (en) 1997-05-30 2011-04-13 Stryker Corporation Methods for evaluating tissue morphogenesis and morphogenic activity
WO1999058671A2 (en) * 1998-05-08 1999-11-18 Research Corporation Technologies, Inc. Human and nematode homologues of the yeast longevity assurance gene lag1
US7147839B2 (en) 1998-05-29 2006-12-12 Curis, Inc. Methods for evaluating tissue morphogenesis and activity
US6872698B2 (en) * 1998-07-06 2005-03-29 Scion Pharmaceuticals, Inc. Methods for treating neurological injuries and disorders
EP1094863A4 (en) * 1998-07-06 2005-02-02 Cambridge Neuroscience Inc METHOD FOR THE TREATMENT OF NEUROLOGICAL INJURIES AND DISEASES
DK1737734T3 (da) 2004-03-10 2010-11-08 Scil Technology Gmbh Overtrukne implantater, deres fremstilling og anvendelse deraf
AU2005247871A1 (en) 2004-04-27 2005-12-08 Research Development Foundation Antagonism of TGF-beta superfamily receptor signaling
ES2369629T3 (es) 2004-05-25 2011-12-02 Stryker Corporation Uso de op-1 para tratar defectos del cartílago.
EP2540310A1 (en) 2006-05-17 2013-01-02 Stryker Corporation Methods of treating cartilage defects using a soluble morphogenic protein complex
AU2007234612B2 (en) 2006-12-14 2013-06-27 Johnson & Johnson Regenerative Therapeutics, Llc Protein stabilization formulations
AU2007339280B2 (en) 2006-12-21 2013-12-05 Stryker Corporation Sustained-release formulations comprising crystals, macromolecular gels, and particulate suspensions of biologic agents
US7678764B2 (en) 2007-06-29 2010-03-16 Johnson & Johnson Regenerative Therapeutics, Llc Protein formulations for use at elevated temperatures
US8058237B2 (en) 2007-08-07 2011-11-15 Advanced Technologies & Regenerative Medicine, LLC Stable composition of GDF-5 and method of storage
JP2011514331A (ja) 2008-02-13 2011-05-06 キース フルスカ， 血管硬化症の治療における使用のためのｂｍｐ−７
EP2276458A1 (en) 2008-04-14 2011-01-26 Advanced Technologies and Regenerative Medicine, LLC Liquid buffered gdf-5 formulations
EP2396025A2 (en) 2009-02-12 2011-12-21 Stryker Corporation Peripheral administration of proteins including tgf-beta superfamily members for systemic treatment of disorders and disease
US20120148539A1 (en) 2009-03-24 2012-06-14 Moulay Hicham Alaoui-Ismaili Methods and Compositions for Tissue Engineering
WO2010144696A1 (en) 2009-06-11 2010-12-16 Burnham Institute For Medical Research Directed differentiation of stem cells
US20110224138A1 (en) 2009-09-09 2011-09-15 Julie Krop Methods for treating pain induced by injuries and diseases of an articular joint
US20110224410A1 (en) 2009-09-17 2011-09-15 Hile David Buffers for Controlling the pH of Bone Morphogenetic Proteins
EP2516456A1 (en) 2009-12-22 2012-10-31 Stryker Corporation Bmp-7 variants with reduced immunogenicity
BR112013003587B1 (pt) 2010-08-20 2022-11-08 Wyeth Llc Proteínas osteogênicas projetadas, seus usos, seu método de produção e molécula de ácido nucleico isolada
US9688735B2 (en) 2010-08-20 2017-06-27 Wyeth Llc Designer osteogenic proteins

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4886747A (en) * 1985-03-22 1989-12-12 Genentech, Inc. Nucleic acid encoding TGF-β and its uses

Also Published As

Publication number Publication date
WO1992000382A1 (en) 1992-01-09
AU8496491A (en) 1992-01-23
JPH06500466A (ja) 1994-01-20
EP0652951A4 (en) 1993-08-16
DE69131580D1 (de) 1999-10-07
EP0652951B1 (en) 1999-09-01
DE69131580T2 (de) 2000-01-13
ES2137931T3 (es) 2000-01-01
CA2085134C (en) 2003-03-18
EP0652951A1 (en) 1995-05-17
US20030040611A1 (en) 2003-02-27
ATE184052T1 (de) 1999-09-15
CA2085134A1 (en) 1991-12-16
AU666291B2 (en) 1996-02-08
US20040039162A1 (en) 2004-02-26

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Legal Events

Date Code Title Description
PF Patent in force
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20040614