HK1011710A1 - Process for the preparation of immunogens or diagnostic reagents and immunogens or diagnostic reagents thereby obtainable - Google Patents

Process for the preparation of immunogens or diagnostic reagents and immunogens or diagnostic reagents thereby obtainable

Info

Publication number: HK1011710A1
Authority: HK; Hong Kong
Prior art keywords: disease; organism; immunogens; fragments; derivatives
Prior art date: 1993-05-11

Application number

HK98112929A

Other languages

English (en)

Inventor

Franco Felici

Alessandra Luzzago

Alfredo Nicosia

Paolo Monaci

Riccardo Cortese

Original Assignee

Istituto Di Recerche Di Biolog

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-05-11

Filing date

1998-12-08

Publication date

1999-07-16

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11401749&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1011710(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1998-12-08 Application filed by Istituto Di Recerche Di Biolog filed Critical Istituto Di Recerche Di Biolog

1999-07-16 Publication of HK1011710A1 publication Critical patent/HK1011710A1/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/02—Libraries contained in or displayed by microorganisms, e.g. bacteria or animal cells; Libraries contained in or displayed by vectors, e.g. plasmids; Libraries containing only microorganisms or vectors
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4713—Autoimmune diseases, e.g. Insulin-dependent diabetes mellitus, multiple sclerosis, rheumathoid arthritis, systemic lupus erythematosus; Autoantigens
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1037—Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/735—Fusion polypeptide containing domain for protein-protein interaction containing a domain for self-assembly, e.g. a viral coat protein (includes phage display)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2730/00—Reverse transcribing DNA viruses
- C12N2730/00011—Details
- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
- C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
- C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/811—Test for named disease, body condition or organ function

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Biophysics (AREA)
Zoology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Engineering & Computer Science (AREA)
Biomedical Technology (AREA)
Wood Science & Technology (AREA)
Microbiology (AREA)
Immunology (AREA)
Bioinformatics & Cheminformatics (AREA)
General Engineering & Computer Science (AREA)
Biotechnology (AREA)
Virology (AREA)
Gastroenterology & Hepatology (AREA)
Plant Pathology (AREA)
General Chemical & Material Sciences (AREA)
Crystallography & Structural Chemistry (AREA)
Physics & Mathematics (AREA)
Rheumatology (AREA)
Rehabilitation Therapy (AREA)
Hematology (AREA)
Diabetes (AREA)
Oncology (AREA)
Chemical Kinetics & Catalysis (AREA)
Toxicology (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Peptides Or Proteins (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

HK98112929A 1993-05-11 1998-12-08 Process for the preparation of immunogens or diagnostic reagents and immunogens or diagnostic reagents thereby obtainable HK1011710A1 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
ITRM930301A IT1270939B (it)	1993-05-11	1993-05-11	Procedimento per la preparazione di immunogeni e reagenti diagnostici,e immunogeni e reagenti diagnostici cosi' ottenibili.
PCT/IT1994/000054 WO1994026886A2 (en)	1993-05-11	1994-05-05	Process for the preparation of immunogens or diagnostic reagents, and immunogens or diagnostic reagents thereby obtainable

Publications (1)

Publication Number	Publication Date
HK1011710A1 true HK1011710A1 (en)	1999-07-16

Family

ID=11401749

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HK98112929A HK1011710A1 (en)	1993-05-11	1998-12-08	Process for the preparation of immunogens or diagnostic reagents and immunogens or diagnostic reagents thereby obtainable

Country Status (15)

Country	Link
US (2)	US5994083A (ja)
EP (1)	EP0698091B1 (ja)
JP (1)	JP2813468B2 (ja)
CN (1)	CN1093881C (ja)
AT (1)	ATE170558T1 (ja)
AU (1)	AU685121B2 (ja)
BR (1)	BR9406595A (ja)
CA (1)	CA2160486C (ja)
DE (1)	DE69413024T2 (ja)
DK (1)	DK0698091T3 (ja)
ES (1)	ES2120046T3 (ja)
HK (1)	HK1011710A1 (ja)
IT (1)	IT1270939B (ja)
RU (1)	RU2136697C1 (ja)
WO (1)	WO1994026886A2 (ja)

Families Citing this family (41)

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US5492807A (en)	1993-11-19	1996-02-20	Santi; Daniel V.	Method of obtaining diagnostic reagents, assays and therapeutics based on clinical manifestations of a disease
JP3830525B2 (ja) *	1995-11-10	2006-10-04	サイトジェン，コーポレーション	組織横断輸送を強化するペプチドとその同定法および使用法
US6361938B1 (en)	1996-11-08	2002-03-26	Elan Corporation, Plc	Peptides which enhance transport across tissues and methods of identifying and using the same
FR2762601B3 (fr)	1997-04-29	1999-06-04	Bio Merieux	Polypeptide capable de reagir avec les anticorps de patients atteints de sclerose en plaques et utilisations
IT1291913B1 (it) *	1997-05-22	1999-01-21	Angeletti P Ist Richerche Bio	Metodo che prevede l'uso di batteriofagi per la rivelazione della presenza di molecole di interesse in campioni biologici
US7588766B1 (en)	2000-05-26	2009-09-15	Elan Pharma International Limited	Treatment of amyloidogenic disease
TWI239847B (en)	1997-12-02	2005-09-21	Elan Pharm Inc	N-terminal fragment of Abeta peptide and an adjuvant for preventing and treating amyloidogenic disease
US20080050367A1 (en)	1998-04-07	2008-02-28	Guriq Basi	Humanized antibodies that recognize beta amyloid peptide
US6761888B1 (en)	2000-05-26	2004-07-13	Neuralab Limited	Passive immunization treatment of Alzheimer's disease
US7964192B1 (en)	1997-12-02	2011-06-21	Janssen Alzheimer Immunotherapy	Prevention and treatment of amyloidgenic disease
US7790856B2 (en)	1998-04-07	2010-09-07	Janssen Alzheimer Immunotherapy	Humanized antibodies that recognize beta amyloid peptide
US6787523B1 (en) *	1997-12-02	2004-09-07	Neuralab Limited	Prevention and treatment of amyloidogenic disease
WO1999033969A1 (en) *	1997-12-31	1999-07-08	Pincus Seth H	A method of isolating a peptide which immunologically mimics microbial carbohydrates including group b streptococcal carbohydrates and the use thereof in a vaccine
GB9810756D0 (en)	1998-05-19	1998-07-15	Angeletti P Ist Richerche Bio	Mimotopes of hypervariable region 1 of the e2 glycoprotein of hcv and uses thereof
US6413721B1 (en)	1998-07-24	2002-07-02	Her Majesty the Queen in Right of Canada, as represented by the “Canadian Food Inspection Agency”	Methods of isolating common and specific antigens from excretory-secretory products of protostrongylidae
SE9803993D0 (sv) *	1998-11-23	1998-11-23	Bjoern Carlsson	New reagent and use thereof
GB9827228D0 (en) *	1998-12-10	1999-02-03	Univ Nottingham	Cancer detection method and reagents
US9974847B2 (en) *	2000-08-24	2018-05-22	Immunitor USA, Inc.	Treatment and prevention of tuberculosis
US20030092145A1 (en) *	2000-08-24	2003-05-15	Vic Jira	Viral vaccine composition, process, and methods of use
GB0024200D0 (en) *	2000-10-03	2000-11-15	Smithkline Beecham Sa	Component vaccine
US7700751B2 (en)	2000-12-06	2010-04-20	Janssen Alzheimer Immunotherapy	Humanized antibodies that recognize β-amyloid peptide
PE20020574A1 (es)	2000-12-06	2002-07-02	Wyeth Corp	Anticuerpos humanizados que reconocen el peptido amiloideo beta
CA2461380C (en)	2001-10-11	2011-03-22	Merck & Co., Inc.	Hepatitis c virus vaccine
CN101988071B (zh)	2001-10-11	2016-07-06	默沙东公司	丙型肝炎病毒疫苗
US20050019751A1 (en) *	2001-11-09	2005-01-27	Riccardo Cortese	Screening for hepatitis c virus entry inhibitors
WO2003074003A2 (en) *	2002-03-01	2003-09-12	Applied Immune Technologies	Immunogens for treatment of neoplastic and infectious disease
MY139983A (en)	2002-03-12	2009-11-30	Janssen Alzheimer Immunotherap	Humanized antibodies that recognize beta amyloid peptide
WO2004098529A2 (en) *	2003-04-30	2004-11-18	Emory University	Therapeutic compositions and vaccines by glycosyl-phosphatidylinositol (gpi)-anchored cytokines and immunostimulatory molecules
TWI374893B (en)	2003-05-30	2012-10-21	Janssen Alzheimer Immunotherap	Humanized antibodies that recognize beta amyloid peptide
ES2396555T3 (es)	2004-12-15	2013-02-22	Janssen Alzheimer Immunotherapy	Anticuerpos que reconocen péptido beta amiloide
EP1838348B1 (en)	2004-12-15	2013-06-26	Janssen Alzheimer Immunotherapy	Humanized amyloid beta antibodies for use in improving cognition
WO2006133911A2 (en)	2005-06-17	2006-12-21	Istituto Di Ricerche Di Biologia Molecolare P Angeletti Spa	Hepatitis c virus nucleic acid vaccine
WO2007087758A2 (es) *	2006-01-31	2007-08-09	Centro De Ingenieria Genetica Y Biotecnologia	Mimotopos de polisacáridos capsulares de neisseria meningitidis y formulaciones farmacéuticas
US8784810B2 (en)	2006-04-18	2014-07-22	Janssen Alzheimer Immunotherapy	Treatment of amyloidogenic diseases
FR2910492B1 (fr)	2006-12-20	2013-02-15	Bio Modeling Systems Ou Bmsystems	Procede de preparation de bacteriophages modifies par insertion de sequences aleatoires dans les proteines de ciblage desdits bacteriophages
US8003097B2 (en)	2007-04-18	2011-08-23	Janssen Alzheimer Immunotherapy	Treatment of cerebral amyloid angiopathy
EP2158220B1 (en) *	2007-06-26	2017-04-19	F-Star Biotechnologische Forschungs- und Entwicklungsges.m.b.H	Display of binding agents
SI2182983T1 (sl)	2007-07-27	2014-09-30	Janssen Alzheimer Immunotherapy	Zdravljenje amiloidogenih bolezni s humaniziranimi protitelesi proti abeta
JO3076B1 (ar)	2007-10-17	2017-03-15	Janssen Alzheimer Immunotherap	نظم العلاج المناعي المعتمد على حالة apoe
US9067981B1 (en)	2008-10-30	2015-06-30	Janssen Sciences Ireland Uc	Hybrid amyloid-beta antibodies
CN114230632B (zh) *	2021-09-18	2023-01-24	华南农业大学	一种丙烯酰胺衍生物模拟表位肽及应用

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US5223409A (en) *	1988-09-02	1993-06-29	Protein Engineering Corp.	Directed evolution of novel binding proteins
US5182366A (en) *	1990-05-15	1993-01-26	Huebner Verena D	Controlled synthesis of peptide mixtures using mixed resins
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IL99553A0 (en) *	1990-09-28	1992-08-18	Ixsys Inc	Compositions containing oligonucleotides linked to expression elements,a kit for the preparation of vectors useful for the expression of a diverse population of random peptides and methods utilizing the same
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DE4122599C2 (de) *	1991-07-08	1993-11-11	Deutsches Krebsforsch	Phagemid zum Screenen von Antikörpern
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US5492807A (en) *	1993-11-19	1996-02-20	Santi; Daniel V.	Method of obtaining diagnostic reagents, assays and therapeutics based on clinical manifestations of a disease

1993
- 1993-05-11 IT ITRM930301A patent/IT1270939B/it active IP Right Grant
1994
- 1994-05-05 WO PCT/IT1994/000054 patent/WO1994026886A2/en active IP Right Grant
- 1994-05-05 RU RU95122726A patent/RU2136697C1/ru active
- 1994-05-05 ES ES94916385T patent/ES2120046T3/es not_active Expired - Lifetime
- 1994-05-05 CA CA002160486A patent/CA2160486C/en not_active Expired - Lifetime
- 1994-05-05 AT AT94916385T patent/ATE170558T1/de active
- 1994-05-05 DK DK94916385T patent/DK0698091T3/da active
- 1994-05-05 BR BR9406595A patent/BR9406595A/pt not_active Application Discontinuation
- 1994-05-05 JP JP6525217A patent/JP2813468B2/ja not_active Expired - Lifetime
- 1994-05-05 EP EP94916385A patent/EP0698091B1/en not_active Expired - Lifetime
- 1994-05-05 DE DE69413024T patent/DE69413024T2/de not_active Expired - Lifetime
- 1994-05-05 US US08/553,257 patent/US5994083A/en not_active Expired - Lifetime
- 1994-05-05 CN CN94192060A patent/CN1093881C/zh not_active Expired - Lifetime
- 1994-05-05 AU AU68069/94A patent/AU685121B2/en not_active Expired
1998
- 1998-12-08 HK HK98112929A patent/HK1011710A1/xx not_active IP Right Cessation
1999
- 1999-11-18 US US09/441,992 patent/US6541210B1/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
ITRM930301A1 (it)	1994-11-11
WO1994026886A2 (en)	1994-11-24
JPH08506493A (ja)	1996-07-16
JP2813468B2 (ja)	1998-10-22
CN1122613A (zh)	1996-05-15
AU685121B2 (en)	1998-01-15
ATE170558T1 (de)	1998-09-15
BR9406595A (pt)	1996-01-02
RU2136697C1 (ru)	1999-09-10
DE69413024T2 (de)	1999-02-04
US5994083A (en)	1999-11-30
ITRM930301A0 (it)	1993-05-11
EP0698091B1 (en)	1998-09-02
CA2160486A1 (en)	1994-11-24
DE69413024D1 (de)	1998-10-08
IT1270939B (it)	1997-05-26
CA2160486C (en)	2001-02-13
EP0698091A1 (en)	1996-02-28
WO1994026886A3 (en)	1995-03-16
CN1093881C (zh)	2002-11-06
ES2120046T3 (es)	1998-10-16
DK0698091T3 (da)	1999-06-07
AU6806994A (en)	1994-12-12
US6541210B1 (en)	2003-04-01

Publication	Publication Date	Title
HK1011710A1 (en)	1999-07-16	Process for the preparation of immunogens or diagnostic reagents and immunogens or diagnostic reagents thereby obtainable
WO1994026886B1 (en)	1995-04-20	Process for the preparation of immunogens or diagnostic reagents, and immunogens or diagnostic reagents thereby obtainable
RU95122726A (ru)	1998-02-27	Способ получения иммуногенов или диагностических реагентов, а также иммуногены и диагностические реагенты, получаемые с его помощью
Burton	1995	Phage display
Scott	1992	Discovering peptide ligands using epitope libraries
Cortese et al.	1994	Epitope discovery using peptide libraries displayed on phage
Legutki et al.	2010	A general method for characterization of humoral immunity induced by a vaccine or infection
JP3135126B2 (ja)	2001-02-13	疾患の臨床的発現に基づく、診断用試薬を得る方法、アッセイ、及び治療剤
AR052377A2 (es)	2007-03-14	Polipeptidos y polinucleotidos de neisseria meningitidis, un huesped unicelular, un metodo para producir una secuencia de adn, un metodo para producir un polipeptido, un metodo para aislar el antigeno, una composicion farmaceutica, uso de una proteina para producir una vacuna destinada para la preve
NO924780L (no)	1993-06-14	Ekspresjon av spesifikke immunogener ved bruk av virusantigener
WO2001088162A3 (en)	2002-09-19	Methods and vectors for generating antibodies in avian species and uses therefor
Jemmerson et al.	1986	Mapping antigenic sites on proteins: Implications for the design of synthetic vaccines.
Valadon et al.	1996	Enhancement of ELISAs for screening peptides in epitope phage display libraries
Zhong et al.	1992	Antigenic analysis of the chlamydial 75-kilodalton protein
CN115286712A (zh)	2022-11-04	新型冠状病毒Delta突变株特异性抗体及其应用
Wang et al.	1997	Cloning of anti-Gal Fabs from combinatorial phage display libraries: structural analysis and comparison of Fab expression in pComb3H and pComb8 phage
CN116355094B (zh)	2023-10-20	抗小鼠白介素12的单克隆抗体及制备方法
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Szecsi et al.	1999	Identification of patient‐specific peptides for detection of M‐proteins and myeloma cells
Barbas et al.	1994	Filamentous phage display
Bradbury	2010	The use of phage display in neurobiology
Tafi et al.	1997	Identification of HCV core mimotopes: improved methods for the selection and use of disease-related phage-displayed peptides
Tarlinton et al.	1998	Affinity maturation of the primary response by V gene diversification
Xin et al.	2004	A subtractive fluorescence-activated cell-sorting strategy to identify mimotopes of HBV–preS protein from bacterially displayed peptide library

Legal Events

Date	Code	Title	Description
2004-12-15	PF	Patent in force
2014-06-06	PE	Patent expired	Effective date: 20140504