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HK1003480A1 - Process for the stabilisation of a solid pharmaceutical composition comprising cyclic amino acids - Google Patents

Process for the stabilisation of a solid pharmaceutical composition comprising cyclic amino acids

Info

Publication number
HK1003480A1
HK1003480A1 HK98102503A HK98102503A HK1003480A1 HK 1003480 A1 HK1003480 A1 HK 1003480A1 HK 98102503 A HK98102503 A HK 98102503A HK 98102503 A HK98102503 A HK 98102503A HK 1003480 A1 HK1003480 A1 HK 1003480A1
Authority
HK
Hong Kong
Prior art keywords
amino acids
cyclic amino
stabilisation
pharmaceutical composition
solid pharmaceutical
Prior art date
Application number
HK98102503A
Other languages
English (en)
Inventor
Helmut Augart
Uwe Gebhardt
Wolfgang Herrmann
Original Assignee
Goedecke Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6387901&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1003480(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Goedecke Ag filed Critical Goedecke Ag
Publication of HK1003480A1 publication Critical patent/HK1003480A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/28—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and containing rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/18—Systems containing only non-condensed rings with a ring being at least seven-membered

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Indole Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Materials Applied To Surfaces To Minimize Adherence Of Mist Or Water (AREA)
  • Cephalosporin Compounds (AREA)
HK98102503A 1989-08-25 1998-03-24 Process for the stabilisation of a solid pharmaceutical composition comprising cyclic amino acids HK1003480A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3928183A DE3928183A1 (de) 1989-08-25 1989-08-25 Lactamfreie cyclische aminosaeuren

Publications (1)

Publication Number Publication Date
HK1003480A1 true HK1003480A1 (en) 1998-10-30

Family

ID=6387901

Family Applications (1)

Application Number Title Priority Date Filing Date
HK98102503A HK1003480A1 (en) 1989-08-25 1998-03-24 Process for the stabilisation of a solid pharmaceutical composition comprising cyclic amino acids

Country Status (11)

Country Link
US (1) US6054482A (de)
EP (1) EP0414263B1 (de)
JP (2) JP3148223B2 (de)
AT (1) ATE113272T1 (de)
DE (2) DE3928183A1 (de)
DK (1) DK0414263T3 (de)
ES (1) ES2063219T3 (de)
HK (1) HK1003480A1 (de)
IE (1) IE65291B1 (de)
MY (1) MY107056A (de)
PT (1) PT95082B (de)

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US6063794A (en) 1996-10-11 2000-05-16 Cor Therapeutics Inc. Selective factor Xa inhibitors
WO1998046591A1 (en) 1997-04-14 1998-10-22 Cor Therapeutics, Inc. SELECTIVE FACTOR Xa INHIBITORS
AU6896398A (en) 1997-04-14 1998-11-11 Cor Therapeutics, Inc. Selective factor xa inhibitors
NZ500353A (en) 1997-04-14 2002-02-01 Cor Therapeutics Inc Cyclic diaza compounds that are selective inhibitors of factor Xa
US6333321B1 (en) 1997-08-11 2001-12-25 Cor Therapeutics, Inc. Selective factor Xa inhibitors
US6228854B1 (en) 1997-08-11 2001-05-08 Cor Therapeutics, Inc. Selective factor Xa inhibitors
US6218382B1 (en) 1997-08-11 2001-04-17 Cor Therapeutics, Inc Selective factor Xa inhibitors
WO1999018063A2 (en) 1997-10-07 1999-04-15 Warner-Lambert Company Process for preparing a cyclic amino acid anticonvulsant compound
DE19751062A1 (de) * 1997-11-18 1999-07-08 Univ Ludwigs Albert An 4-Stellung substituierte 2-Pyrrolidinon-Derivate zur Verringerung des extrazellulären Glutamat-Spiegels
US6984659B2 (en) 1997-11-18 2006-01-10 Klinikum Der Albert-Ludwigs Universitaet 2-pyrrolidinone derivatives substituted at position 4 for reducing the extracellular glutamate level
HU228772B1 (en) * 1998-05-15 2013-05-28 Warner Lambert Co Gamma-aminobutyric acid derivatives containing, solid compositions and process for preparing the same
CA2327285C (en) * 1998-05-15 2005-06-14 Warner-Lambert Company Stabilized pharmaceutical preparations of gamma-aminobutyric acid derivatives and process for preparing the same
HU225502B1 (en) 1998-12-29 2007-01-29 Richter Gedeon Vegyeszet Process for producing 1-(amino-metyl)-cyclohexene-acetic-acid and intermediates
US6294198B1 (en) 1999-08-24 2001-09-25 Purepac Pharmaceutical Co. Pharmaceutical tablet formulation containing gabapentin with improved physical and chemical characteristics and method of making the same
DK1289364T3 (da) * 2000-06-16 2004-04-13 Teva Pharma Stabil gapapentin som indeholder mere end 20 ppm chlorioner
CZ200339A3 (cs) * 2000-06-16 2003-06-18 Teva Pharmaceutical Industries Ltd. Stabilní gabapentin vykazující neutrální pH
EP1384473A1 (de) * 2000-06-16 2004-01-28 Teva Pharmaceutical Industries Ltd. Stabiles Gabapentin das mehr als 20 ppm Chlor enthält
US7056951B2 (en) 2000-09-26 2006-06-06 Mutual Pharmaceutical Co., Inc. Stable solid dosage forms of amino acids and processes for producing same
IT1319234B1 (it) 2000-10-23 2003-09-26 Zambon Spa Processo di preparazione di gabapentina.
DE60142305D1 (de) 2000-11-17 2010-07-15 Takeda Pharmaceutical Pharmazeutische zubereitung enthaltend n-ä2-(1,6,7,8-tetrahydro-2h-indenoä5,4 büfuran-8-yl)ethylüpropionamid ummantelt mit einer copolyvidon-enthaltenden, polyäthylenglykolfreien umhüllung
US6818787B2 (en) * 2001-06-11 2004-11-16 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
US8048917B2 (en) * 2005-04-06 2011-11-01 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
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NZ567711A (en) 2001-06-11 2009-10-30 Xenoport Inc Orally administered dosage forms of GABA analog prodrugs having reduced toxicity
US8354438B2 (en) * 2001-08-08 2013-01-15 Michael Chez Neurological functions
US20060159743A1 (en) * 2001-10-25 2006-07-20 Depomed, Inc. Methods of treating non-nociceptive pain states with gastric retentive gabapentin
US7612112B2 (en) 2001-10-25 2009-11-03 Depomed, Inc. Methods of treatment using a gastric retained gabapentin dosage
US20070184104A1 (en) * 2001-10-25 2007-08-09 Depomed, Inc. Gastric retentive gabapentin dosage forms and methods for using same
TWI312285B (en) 2001-10-25 2009-07-21 Depomed Inc Methods of treatment using a gastric retained gabapentin dosage
US20030119908A1 (en) * 2001-12-21 2003-06-26 Zambon Group S.P.A. Stable gabapentin compositions
ITMI20012750A1 (it) 2001-12-21 2003-06-21 Procos Spa Processo per la produzione dell'acido 1-(amminometil)-cicloesil-acetico in forma pura
US6682759B2 (en) 2002-02-01 2004-01-27 Depomed, Inc. Manufacture of oral dosage forms delivering both immediate-release and sustained-release drugs
AU2003222033A1 (en) 2002-03-20 2003-10-08 Xenoport Cyclic 1-(acyloxy)-alkyl prodrugs of gaba analogs, compositions and uses thereof
EP1494996A1 (de) * 2002-04-16 2005-01-12 Taro Pharmaceutical Industries Limited Verfahren zur herstellung von gabapentin
EP1513504A1 (de) * 2002-06-07 2005-03-16 Ranbaxy Laboratories, Ltd. Orale dosierformen von gabapentin mit verzögerter freisetzung
CA2395931A1 (en) * 2002-08-07 2004-02-07 Bernard Charles Sherman Solid compositions comprising gabapentin having improved stability
ITMI20022071A1 (it) * 2002-10-01 2004-04-02 Erregierre Spa Processo di sintesi dell'acido 1-(aminometil)cicloesanacetico cloridato.
US20060039968A1 (en) * 2002-10-08 2006-02-23 Ramalingam Manikandan Gabapentin tablets and method for their preparation
DE60315258T2 (de) * 2002-12-20 2008-05-08 Dynogen Pharmaceuticals Inc., Waltham Behandlung von nicht-schmerzhaften blasenstörungen mit modulatoren der alpha-2-delta-untereinheit des calciumkanals
CA2519694A1 (en) * 2003-03-21 2004-10-07 Dynogen Pharmaceuticals, Inc. Methods for treating lower urinary tract disorders using smooth muscle modulators and alpha-2-delta subunit calcium channel modulators
US20040214893A1 (en) * 2003-04-11 2004-10-28 Matthew Peterson Gabapentin compositions
ITMI20030825A1 (it) * 2003-04-18 2004-10-19 Farchemia Srl Procedimento per la preparazione di gabapentin esente da
ITMI20031247A1 (it) 2003-06-20 2004-12-21 Zambon Spa Processo per la purificazione di gabapentina
US7169812B2 (en) * 2003-07-01 2007-01-30 Medtronic, Inc. Process for producing injectable gabapentin compositions
US20050013863A1 (en) 2003-07-18 2005-01-20 Depomed, Inc., A Corporation Of The State Of California Dual drug dosage forms with improved separation of drugs
WO2005046566A2 (en) * 2003-08-04 2005-05-26 Sun Pharmaceutical Industries Limited Stable gabapentin containing composition
CA2537837A1 (en) * 2003-09-11 2005-03-24 Xenoport, Inc. Treating and/or preventing urinary incontinence using prodrugs of gaba analogs
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JP4308263B2 (ja) 2003-10-14 2009-08-05 ゼノポート，インコーポレイティド γ−アミノ酪酸アナログの結晶形
US20050090549A1 (en) * 2003-10-23 2005-04-28 Medtronic, Inc. Intrathecal gabapentin for treatment of pain
US20050090548A1 (en) * 2003-10-23 2005-04-28 Medtronic, Inc. Intrathecal gabapentin for treatment of epilepsy
US20050187295A1 (en) * 2004-02-19 2005-08-25 Surendra Kalyan Processes for the preparation of gabapentin
US20050209319A1 (en) * 2004-03-18 2005-09-22 Xenoport, Inc. Treatment of local pain
ITMI20041447A1 (it) * 2004-07-20 2004-10-20 Zambon Spa Composizione farmaceutica comprendente gabapentina
CN100361964C (zh) * 2005-06-13 2008-01-16 江苏恩华药业股份有限公司 盐酸加巴喷丁及其中间体的制备方法
US20070049626A1 (en) * 2005-08-26 2007-03-01 Tran Pierre V Treating premature ejaculation using gabapentin and pregabalin prodrugs
US20070092565A1 (en) * 2005-10-25 2007-04-26 Pharmascience Inc. Gastric retention drug delivery system
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AU2007332904A1 (en) * 2006-12-08 2008-06-19 Xenoport, Inc. Use of prodrugs of GABA analogs for treating diseases
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CN101462975B (zh) * 2008-08-19 2012-07-25 宁波九胜创新医药科技有限公司 一种高纯度加巴喷丁的制备方法
HU230031B1 (hu) 2010-03-01 2015-05-28 Egis Gyógyszergyár Nyilvánosan Működő Részvénytársaság Pregabalint és izomaltot tartalmazó stabilizált gyógyszerkészítmény
WO2014163132A1 (ja) * 2013-04-04 2014-10-09 第一三共株式会社 アミノカルボン酸の塩の固形組成物
EP3513788B1 (de) 2015-03-19 2020-07-29 Daiichi Sankyo Company, Limited Feststoffpräparat mit farbstoff
CN107405322B (zh) 2015-03-19 2020-08-18 第一三共株式会社 含有抗氧化剂的固体制剂
CA3073229A1 (en) 2017-08-18 2019-02-21 Abbvie Inc. Pharmaceutical formulations for treating endometriosis, uterine fibroids, polycystic ovary syndrome or adenomyosis
TW201912157A (zh) 2017-08-18 2019-04-01 美商艾伯維有限公司 治療子宮內膜異位症、子宮纖維瘤、多囊性卵巢症候群及子宮腺肌症之固體醫藥調配物
JP7138666B2 (ja) * 2018-01-24 2022-09-16 大原薬品工業株式会社 γ－アミノ酪酸誘導体含有錠剤の化学的安定性を改善する方法
JP7312751B2 (ja) 2018-07-30 2023-07-21 第一三共株式会社 安定化剤を含有する医薬品の固形製剤
RU2736479C1 (ru) * 2019-07-30 2020-11-17 Общество С Ограниченной Ответственностью "Консорциум-Пик" Не содержащая наполнитель фармацевтическая композиция, содержащая фенозановую кислоту
RU2731536C1 (ru) * 2019-07-30 2020-09-04 Общество С Ограниченной Ответственностью "Консорциум-Пик" Фармацевтические композиции, содержащие фенозановую кислоту

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Also Published As

Publication number Publication date
JPH0390053A (ja) 1991-04-16
EP0414263A3 (en) 1991-06-05
JP2001058976A (ja) 2001-03-06
DE59007550D1 (de) 1994-12-01
JP3148223B2 (ja) 2001-03-19
DK0414263T3 (da) 1995-01-16
ATE113272T1 (de) 1994-11-15
ES2063219T3 (es) 1995-01-01
EP0414263B1 (de) 1994-10-26
JP3261123B2 (ja) 2002-02-25
PT95082B (pt) 1997-04-30
DE3928183A1 (de) 1991-02-28
IE65291B1 (en) 1995-10-18
IE903089A1 (en) 1991-02-27
PT95082A (pt) 1991-04-18
US6054482A (en) 2000-04-25
EP0414263A2 (de) 1991-02-27
MY107056A (en) 1995-09-30

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Effective date: 20100823