GR3029717T3 - HYBRID PROTEIN BETWEEN CS FROM PLASMODIUM AND HBsAG. - Google Patents
HYBRID PROTEIN BETWEEN CS FROM PLASMODIUM AND HBsAG.Info
- Publication number
- GR3029717T3 GR3029717T3 GR990400668T GR990400668T GR3029717T3 GR 3029717 T3 GR3029717 T3 GR 3029717T3 GR 990400668 T GR990400668 T GR 990400668T GR 990400668 T GR990400668 T GR 990400668T GR 3029717 T3 GR3029717 T3 GR 3029717T3
- Authority
- GR
- Greece
- Prior art keywords
- hbsag
- plasmodium
- hybrid protein
- protein
- falciparum
- Prior art date
Links
- 102000004169 proteins and genes Human genes 0.000 title abstract 4
- 108090000623 proteins and genes Proteins 0.000 title abstract 4
- 241000224016 Plasmodium Species 0.000 title 1
- 241000700721 Hepatitis B virus Species 0.000 abstract 1
- 241000223960 Plasmodium falciparum Species 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 238000002255 vaccination Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
- C07K14/445—Plasmodium
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2730/00—Reverse transcribing DNA viruses
- C12N2730/00011—Details
- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
- C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2730/00—Reverse transcribing DNA viruses
- C12N2730/00011—Details
- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
- C12N2730/10123—Virus like particles [VLP]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Virology (AREA)
- Gastroenterology & Hepatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Microbiology (AREA)
- Toxicology (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Engineering & Computer Science (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB919124390A GB9124390D0 (en) | 1991-11-16 | 1991-11-16 | Vaccines |
US84269492A | 1992-02-27 | 1992-02-27 | |
PCT/EP1992/002591 WO1993010152A1 (en) | 1991-11-16 | 1992-11-11 | HYBRID PROTEIN BETWEEN CS FROM PLASMODIUM AND HBsAG |
Publications (1)
Publication Number | Publication Date |
---|---|
GR3029717T3 true GR3029717T3 (en) | 1999-06-30 |
Family
ID=26299880
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GR990400668T GR3029717T3 (en) | 1991-11-16 | 1999-03-18 | HYBRID PROTEIN BETWEEN CS FROM PLASMODIUM AND HBsAG. |
Country Status (15)
Country | Link |
---|---|
EP (1) | EP0614465B1 (el) |
JP (2) | JP3954643B2 (el) |
KR (1) | KR100251505B1 (el) |
AT (1) | ATE177755T1 (el) |
AU (2) | AU2927892A (el) |
CA (1) | CA2123612C (el) |
DE (1) | DE69228698T2 (el) |
DK (1) | DK0614465T3 (el) |
ES (1) | ES2129461T3 (el) |
GR (1) | GR3029717T3 (el) |
MX (1) | MX9206574A (el) |
NZ (1) | NZ245114A (el) |
PT (1) | PT101052B (el) |
SG (1) | SG48390A1 (el) |
WO (1) | WO1993010152A1 (el) |
Families Citing this family (74)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6620414B2 (en) | 1992-03-27 | 2003-09-16 | Smithkline Beecham Biologicals (S.A.) | Hepatitis vaccines containing 3-0-deacylated monophoshoryl lipid A |
ES2143716T3 (es) | 1992-06-25 | 2000-05-16 | Smithkline Beecham Biolog | Composicion de vacuna que contiene adyuvantes. |
GB9616351D0 (en) * | 1996-08-02 | 1996-09-11 | Smithkline Beecham Biolog | Vaccine composition |
SI1126876T1 (sl) | 1998-10-16 | 2007-08-31 | Glaxosmithkline Biolog Sa | Adjuvantni sistemi in vakcine |
GB9915204D0 (en) * | 1999-06-29 | 1999-09-01 | Smithkline Beecham Biolog | Vaccine |
GB0109297D0 (en) | 2001-04-12 | 2001-05-30 | Glaxosmithkline Biolog Sa | Vaccine |
NZ539509A (en) | 2002-10-23 | 2008-05-30 | Glaxosmithkline Biolog Sa | Priming vaccine comprising a polynucleotide encoding at least one first malarial antigen and a boosting vaccine comprising at least one polypeptide comprising at least one second malarial antigen having at least one epitope in common with the first malarial antigen of the priming vaccine |
NZ539813A (en) | 2002-12-17 | 2008-04-30 | Crucell Holland Bv | A replication defective recombinant adenovirus comprising a antigenic determinant of Plasmodium falciparum wherein the antigenic determinant is SEQ ID 6 |
CN1298742C (zh) * | 2003-06-03 | 2007-02-07 | 上海新药研究开发中心 | 一种适合于高效表达的融合蛋白及其生产方法 |
CA2678736A1 (en) | 2003-07-21 | 2005-02-17 | Transgene S.A. | Novel multifunctional il-2 - il-18 fusion proteins |
GB0420634D0 (en) * | 2004-09-16 | 2004-10-20 | Glaxosmithkline Biolog Sa | Vaccines |
CN101068568B (zh) * | 2004-10-14 | 2012-09-26 | 克鲁塞尔荷兰公司 | 抗疟疾的初始/加强免疫疫苗 |
US8119146B2 (en) * | 2005-04-18 | 2012-02-21 | Angelica Medina-Selby | Expressing hepatitis B virus surface antigen for vaccine preparation |
GB0513421D0 (en) * | 2005-06-30 | 2005-08-03 | Glaxosmithkline Biolog Sa | Vaccines |
TWI457133B (zh) | 2005-12-13 | 2014-10-21 | Glaxosmithkline Biolog Sa | 新穎組合物 |
GB0614254D0 (en) * | 2006-07-18 | 2006-08-30 | Smithkline Beecham Biolog | Vaccine |
BRPI0715581A2 (pt) * | 2006-07-18 | 2013-04-24 | Glaxosmithkline Biolog Sa | proteÍna de fusço hÍbrida imunogÊnica, composiÇço, uso de uma proteÍna ou uma partÍcula, mÉtodo para tratar um paciente suscetÍvel À infecÇço por plasmàdio, sequÊncia de nucleotÍdeo, hospedeiro, e, processo para a produÇço de proteÍna |
EP2097102B1 (en) | 2006-09-07 | 2012-05-30 | GlaxoSmithKline Biologicals s.a. | Combination vaccine having reduced polio virus antigen quantities |
DK2468300T3 (da) | 2006-09-26 | 2018-01-29 | Infectious Disease Res Inst | Vaccinesammensætning indeholdende syntetisk adjuvant |
US20090181078A1 (en) | 2006-09-26 | 2009-07-16 | Infectious Disease Research Institute | Vaccine composition containing synthetic adjuvant |
SI2086582T1 (sl) | 2006-10-12 | 2013-02-28 | Glaxosmithkline Biologicals S.A. | Cepivo, ki obsega emulzijo olja v vodi kot adjuvans |
HRP20130023T1 (hr) | 2006-10-12 | 2013-02-28 | Glaxosmithkline Biologicals S.A. | Cjepivo koje sadrži emulziju ulje u vodi kao adjuvans |
US9717788B2 (en) | 2007-03-02 | 2017-08-01 | Glaxosmithkline Biologicals Sa | Method of inducing an immune response against HIV employing HIV immunogens, adenoviral vectors encoding said immunogens, and adjuvant |
CL2008000611A1 (es) | 2007-03-02 | 2008-09-05 | Glaxosmithkline Biolog Sa | Procedimiento para fomentar respuesta inmunitaria frente a un patogeno que comprende administrar i) uno o mas polipeptidos inmunogenicos derivados del patogeno, ii) uno o mas vectores adenoviricos que comprenden uno o mas polinucleotidos que codifica |
TW200908994A (en) | 2007-04-20 | 2009-03-01 | Glaxosmithkline Biolog Sa | Vaccine |
TW200924791A (en) | 2007-08-13 | 2009-06-16 | Glaxosmithkline Biolog Sa | Vaccines |
CN101951947A (zh) | 2007-12-24 | 2011-01-19 | 葛兰素史密丝克莱恩生物有限公司 | 疟疾疫苗 |
GB0815872D0 (en) | 2008-09-01 | 2008-10-08 | Pasteur Institut | Novel method and compositions |
JP5830015B2 (ja) | 2009-06-05 | 2015-12-09 | インフェクシャス ディズィーズ リサーチ インスティチュート | 合成グルコピラノシル脂質アジュバント |
US9555089B2 (en) | 2009-08-18 | 2017-01-31 | The Rockefeller University | Modification of recombinant adenovirus with immunogenic plasmodium circumsporozoite protein epitopes |
WO2012041669A1 (en) | 2010-09-27 | 2012-04-05 | Crucell Holland B.V. | Heterologous prime boost vaccination regimen against malaria |
GB201022007D0 (en) | 2010-12-24 | 2011-02-02 | Imp Innovations Ltd | DNA-sensor |
EA027236B1 (ru) | 2011-04-08 | 2017-07-31 | Иммьюн Дизайн Корп. | Иммуногенные композиции и способы применения таких композиций для индукции гуморального и клеточного иммунного ответа |
GB201116248D0 (en) | 2011-09-20 | 2011-11-02 | Glaxosmithkline Biolog Sa | Liposome production using isopropanol |
RS58868B1 (sr) | 2012-02-07 | 2019-08-30 | Infectious Disease Res Inst | Poboljšane adjuvansne formulacije koje sadrže agoniste tlr4 i postupci upotrebe istih |
SG11201404711WA (en) | 2012-02-16 | 2014-09-26 | Vlp Therapeutics Llc | Virus like particle composition |
EP3388835B1 (en) | 2012-05-16 | 2020-04-01 | Immune Design Corp. | Vaccines for hsv-2 |
JP6430949B2 (ja) | 2012-10-23 | 2018-11-28 | エモリー ユニバーシティ | Gm−csfとil−4のコンジュゲート、組成物、ならびにそれに関連する方法 |
JPWO2014103608A1 (ja) | 2012-12-25 | 2017-01-12 | 一般財団法人化学及血清療法研究所 | HPV/HBsキメラタンパク質を有効成分とするHPV感染症及び/又はB型肝炎用ワクチン |
EP2941269B1 (en) | 2013-01-07 | 2020-12-09 | Mucosal Vaccine Technologies LLC | Therapeutic vaccines for treating herpes simplex virus type 2 infections |
EP2945649B1 (en) | 2013-01-22 | 2018-12-12 | Oxford University Innovation Limited | Composition and uses thereof |
UY35418A (es) | 2013-03-15 | 2014-10-31 | Glaxosmithkline Biolog Sa | Vacuna que proporciona protección frente a diferentes Picornavirus humanos. |
KR102039520B1 (ko) | 2013-04-18 | 2019-11-01 | 이뮨 디자인 코포레이션 | 암 치료에 이용하기 위한 gla 단일요법 |
EP3004348B1 (en) | 2013-06-03 | 2023-03-08 | VLP Therapeutics, Inc. | Malaria vaccine |
US9463198B2 (en) | 2013-06-04 | 2016-10-11 | Infectious Disease Research Institute | Compositions and methods for reducing or preventing metastasis |
TWI676636B (zh) | 2013-07-12 | 2019-11-11 | Vlp醫療股份有限公司 | 包含pd-1抗原或pd-1配體抗原的類病毒粒子 |
EP2873728A1 (en) | 2013-11-18 | 2015-05-20 | Institut Pasteur | A subunit vaccine platform based on multimeric ribonucleoproteins comprising nucleoproteins of a non-segmented negative-strand RNA virus as carriers of heterologous polypeptides |
US11801223B2 (en) | 2013-12-31 | 2023-10-31 | Access To Advanced Health Institute | Single vial vaccine formulations |
TWI720946B (zh) | 2014-08-08 | 2021-03-11 | 美商Vlp醫療股份有限公司 | 包含改質套膜蛋白質e3之類病毒粒子 |
US10385101B2 (en) | 2014-08-08 | 2019-08-20 | Vlp Therapeutics, Llc | Virus like particle comprising modified envelope protein E3 |
US10189877B2 (en) | 2014-09-01 | 2019-01-29 | International Centre For Genetic Engineering And Biotechnology | Tetravalent dengue vaccine |
MX383330B (es) | 2014-09-11 | 2025-03-13 | Vlp Therapeutics Inc | Particula tipo virus de flavivirus. |
WO2016184784A1 (en) | 2015-05-15 | 2016-11-24 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Peptides including binding domain of plasmodium falciparum proteins (cbp1 and cbp2) to chemokine cx3cl1 |
WO2017176076A1 (en) | 2016-04-06 | 2017-10-12 | Ewha University - Industry Collaboration Foundation | A peptide with ability to penetrate cell membrane |
JP7195147B2 (ja) | 2016-05-16 | 2022-12-23 | アクセス ツー アドバンスト ヘルス インスティチュート | Peg化リポソームおよび使用方法 |
IL314130A (en) | 2016-05-16 | 2024-09-01 | Access To Advanced Health Inst | Formulation containing tlr agonist and methods of use |
US11173126B2 (en) | 2016-06-01 | 2021-11-16 | Infectious Disease Research Institute | Nanoalum particles comprising a PAA sizing agent |
ES2988600T3 (es) | 2016-12-07 | 2024-11-21 | Glaxosmithkline Biologicals Sa | Proceso para elaborar una composición de liposoma que comprende una saponina |
GB201621686D0 (en) | 2016-12-20 | 2017-02-01 | Glaxosmithkline Biologicals Sa | Novel methods for inducing an immune response |
GB201707700D0 (en) | 2017-05-12 | 2017-06-28 | Glaxosmithkline Biologicals Sa | Dried composition |
CA3063954A1 (en) | 2017-05-30 | 2018-12-06 | Glaxosmithline Biologicals S.A. | Methods for manufacturing an adjuvant |
CN111315362A (zh) | 2017-06-15 | 2020-06-19 | 传染病研究所 | 纳米结构脂质载剂和稳定乳剂以及其用途 |
CN111315406A (zh) | 2017-09-08 | 2020-06-19 | 传染病研究所 | 包括皂苷的脂质体调配物及其使用方法 |
WO2019106192A1 (en) | 2017-12-01 | 2019-06-06 | Glaxosmithkline Biologicals Sa | Saponin purification |
CA3086219A1 (en) | 2017-12-20 | 2019-06-27 | Vlp Therapeutics, Llc | Alphavirus replicon particle |
US20220177558A1 (en) | 2019-03-25 | 2022-06-09 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Treatment of taupathy disorders by targeting new tau species |
CN114340665A (zh) | 2019-05-25 | 2022-04-12 | 传染病研究所 | 用于对佐剂疫苗乳剂进行喷雾干燥的组合物和方法 |
BR112021024363A2 (pt) | 2019-06-05 | 2022-03-22 | Glaxosmithkline Biologicals Sa | Purificação de saponina |
JP7644993B2 (ja) | 2020-04-17 | 2025-03-13 | ブイエルピー・セラピューティクス・インコーポレイテッド | コロナウイルスワクチン |
KR20230005883A (ko) | 2020-04-30 | 2023-01-10 | 브이엘피 테라퓨틱스 인코포레이티드 | 사이토카인 면역요법 |
AU2021337493A1 (en) | 2020-09-04 | 2023-05-18 | Access To Advanced Health Institute | Co-lyophilized rna and nanostructured lipid carrier |
WO2022266383A1 (en) | 2021-06-17 | 2022-12-22 | Atreca, Inc. | Anti-csp antibodies |
EP4169513A1 (en) | 2021-10-19 | 2023-04-26 | GlaxoSmithKline Biologicals S.A. | Adjuvant composition comprising sting agonists |
AU2023336224A1 (en) | 2022-09-09 | 2025-03-27 | Access To Advanced Health Institute | Immunogenic vaccine composition incorporating a saponin |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0175261B1 (en) * | 1984-09-12 | 1991-12-11 | Chiron Corporation | Hybrid particle immunogens |
US4722840A (en) * | 1984-09-12 | 1988-02-02 | Chiron Corporation | Hybrid particle immunogens |
AP56A (en) * | 1987-01-30 | 1989-09-26 | Smithkline Biologicals S A | Hepatitis B virus surface antigens and hybrid antigehs containing them. |
US4886782A (en) * | 1987-02-26 | 1989-12-12 | The United States Of America As Represented By The Department Of Health And Human Services | Malarial immunogen |
KR890701742A (ko) * | 1987-06-22 | 1989-12-21 | 메디코 랩스 에이지 | 이형바이러스 펩티드 입자 임뮤노겐 |
GB8812214D0 (en) * | 1988-05-24 | 1988-06-29 | Hoffmann La Roche | Use of peptide from circumsporozoite protein of p falciparum as universally recognized t-cell epitope |
US5028425A (en) * | 1988-07-07 | 1991-07-02 | The United States Of America As Represented By The Department Of Health And Human Services | Synthetic vaccine against P. falciparum malaria |
-
1992
- 1992-11-11 AU AU29278/92A patent/AU2927892A/en not_active Abandoned
- 1992-11-11 ES ES92923486T patent/ES2129461T3/es not_active Expired - Lifetime
- 1992-11-11 DK DK92923486T patent/DK0614465T3/da active
- 1992-11-11 WO PCT/EP1992/002591 patent/WO1993010152A1/en active IP Right Grant
- 1992-11-11 SG SG1996009300A patent/SG48390A1/en unknown
- 1992-11-11 CA CA002123612A patent/CA2123612C/en not_active Expired - Lifetime
- 1992-11-11 AT AT92923486T patent/ATE177755T1/de active
- 1992-11-11 JP JP50895793A patent/JP3954643B2/ja not_active Expired - Lifetime
- 1992-11-11 EP EP92923486A patent/EP0614465B1/en not_active Expired - Lifetime
- 1992-11-11 DE DE69228698T patent/DE69228698T2/de not_active Expired - Lifetime
- 1992-11-11 KR KR1019940701652A patent/KR100251505B1/ko not_active Expired - Lifetime
- 1992-11-13 MX MX9206574A patent/MX9206574A/es unknown
- 1992-11-13 PT PT101052A patent/PT101052B/pt not_active IP Right Cessation
- 1992-11-13 NZ NZ245114A patent/NZ245114A/en not_active IP Right Cessation
-
1997
- 1997-02-14 AU AU14717/97A patent/AU712409B2/en not_active Expired
-
1999
- 1999-03-18 GR GR990400668T patent/GR3029717T3/el unknown
-
2007
- 2007-03-15 JP JP2007066032A patent/JP4241846B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
CA2123612A1 (en) | 1993-05-27 |
AU2927892A (en) | 1993-06-15 |
NZ245114A (en) | 1995-07-26 |
AU712409B2 (en) | 1999-11-04 |
DE69228698D1 (de) | 1999-04-22 |
JP3954643B2 (ja) | 2007-08-08 |
EP0614465A1 (en) | 1994-09-14 |
HK1012405A1 (en) | 1999-07-30 |
JP2007209343A (ja) | 2007-08-23 |
WO1993010152A1 (en) | 1993-05-27 |
JPH07501213A (ja) | 1995-02-09 |
DE69228698T2 (de) | 1999-09-16 |
ES2129461T3 (es) | 1999-06-16 |
PT101052B (pt) | 1999-10-29 |
MX9206574A (es) | 1993-05-01 |
JP4241846B2 (ja) | 2009-03-18 |
ATE177755T1 (de) | 1999-04-15 |
EP0614465B1 (en) | 1999-03-17 |
CA2123612C (en) | 2002-06-25 |
PT101052A (pt) | 1994-01-31 |
SG48390A1 (en) | 1998-04-17 |
DK0614465T3 (da) | 1999-09-27 |
AU1471797A (en) | 1997-06-12 |
KR100251505B1 (ko) | 2000-05-01 |
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