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GR3025846T3 - Expression of the binding subunit of cholera toxin with the aid of foreign promoters and/or leader sequences - Google Patents

Expression of the binding subunit of cholera toxin with the aid of foreign promoters and/or leader sequences

Info

Publication number
GR3025846T3
GR3025846T3 GR970402939T GR970402939T GR3025846T3 GR 3025846 T3 GR3025846 T3 GR 3025846T3 GR 970402939 T GR970402939 T GR 970402939T GR 970402939 T GR970402939 T GR 970402939T GR 3025846 T3 GR3025846 T3 GR 3025846T3
Authority
GR
Greece
Prior art keywords
cholera toxin
aid
expression
binding subunit
foreign
Prior art date
Application number
GR970402939T
Other languages
English (en)
Inventor
Jan Holmgren
Castillo Joaquin Sanches
Original Assignee
Vitec Aktiebolag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vitec Aktiebolag filed Critical Vitec Aktiebolag
Publication of GR3025846T3 publication Critical patent/GR3025846T3/el

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70Vectors or expression systems specially adapted for E. coli
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/245Escherichia (G)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/28Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Vibrionaceae (F)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/036Fusion polypeptide containing a localisation/targetting motif targeting to the medium outside of the cell, e.g. type III secretion
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/55Fusion polypeptide containing a fusion with a toxin, e.g. diphteria toxin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Soy Sauces And Products Related Thereto (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Exhaust Gas Treatment By Means Of Catalyst (AREA)
GR970402939T 1988-09-16 1998-01-08 Expression of the binding subunit of cholera toxin with the aid of foreign promoters and/or leader sequences GR3025846T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8803291A SE462285B (sv) 1988-09-16 1988-09-16 Expression av koleratoxinets bindande subenhet med hjaelp av fraemmande promotor- och/eller ledarpeptidstrukturer

Publications (1)

Publication Number Publication Date
GR3025846T3 true GR3025846T3 (en) 1998-04-30

Family

ID=20373364

Family Applications (1)

Application Number Title Priority Date Filing Date
GR970402939T GR3025846T3 (en) 1988-09-16 1998-01-08 Expression of the binding subunit of cholera toxin with the aid of foreign promoters and/or leader sequences

Country Status (13)

Country Link
EP (1) EP0368819B1 (el)
JP (1) JP2790333B2 (el)
AT (1) ATE161885T1 (el)
AU (1) AU633842B2 (el)
CA (1) CA1340577C (el)
DE (1) DE68928529T2 (el)
DK (1) DK175694B1 (el)
ES (1) ES2113342T3 (el)
FI (1) FI104496B (el)
GR (1) GR3025846T3 (el)
IS (1) IS1804B (el)
NO (1) NO301175B1 (el)
SE (1) SE462285B (el)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH03187383A (ja) * 1989-09-04 1991-08-15 Takeda Chem Ind Ltd 発現プラスミドおよびその用途
US5356797A (en) * 1991-11-15 1994-10-18 Board Of Regents, The University Of Texas Membrane expression of heterologous genes
EP0613500A1 (en) * 1991-11-15 1994-09-07 The Board Of Regents, The University Of Texas System Membrane expression of heterologous genes
US5932714A (en) * 1995-02-23 1999-08-03 Connaught Laboratories Limited Expression of gene products from genetically manipulated strains of Bordetella
US5998168A (en) * 1995-06-07 1999-12-07 Connaught Laboratories Limited Expression of gene products from genetically manipulated strains of bordetella
US6008329A (en) * 1998-03-06 1999-12-28 The United States Of America As Represented By The Secretary Of The Army Method for purifying cholera toxin
WO2007117339A2 (en) * 2006-01-11 2007-10-18 The United States Of America As Respresented By The Secretary Of The Navy Adhesin-enterotoxin chimera based immunogenic composition against entertoxigenic escherichia coli
DE102011111688A1 (de) * 2011-08-24 2013-02-28 Bioserv Analytik Und Medizinprodukte Gmbh Verfahren zur schnellen Isolation bzw. Aufreinigung von rekombinanten Proteinen mit einer (nicht toxischen) Choleratoxin-Domäne
CN109096403B (zh) * 2018-07-04 2020-06-30 浙江工商大学 一种用于蛋白质转导的蛋白质载体及其制备方法和应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4666837A (en) * 1982-05-24 1987-05-19 Smithkline-Rit DNA sequences, recombinant DNA molecules and processes for producing the A and B subunits of cholera toxin and preparations containing so-obtained subunit or subunits
US5135862A (en) * 1983-03-04 1992-08-04 University Of Maryland Method of isolating restriction fragment deletions in vibrio cholerae, products thereof
US4882278A (en) * 1983-04-29 1989-11-21 President And Fellows Of Harvard College Non-toxinogenic vibrio cholerae mutants
EP0251579A3 (en) * 1986-06-24 1989-03-22 Enterovax Research Pty. Ltd. Non-antibiotic marker system
DE3856199T2 (de) * 1987-04-29 1999-02-04 The President and Fellows of Harvard College, Cambridge, Mass. Impfstoff gegen cholera

Also Published As

Publication number Publication date
FI894368A (fi) 1990-03-17
IS1804B (is) 2002-02-26
NO301175B1 (no) 1997-09-22
SE8803291D0 (sv) 1988-09-16
EP0368819A1 (en) 1990-05-16
JPH0322997A (ja) 1991-01-31
DK456989A (da) 1990-03-17
AU633842B2 (en) 1993-02-11
JP2790333B2 (ja) 1998-08-27
ES2113342T3 (es) 1998-05-01
NO893702L (no) 1990-03-19
ATE161885T1 (de) 1998-01-15
FI104496B (fi) 2000-02-15
FI894368A0 (fi) 1989-09-15
DK456989D0 (da) 1989-09-15
SE462285B (sv) 1990-05-28
NO893702D0 (no) 1989-09-15
DE68928529D1 (de) 1998-02-12
EP0368819B1 (en) 1998-01-07
DE68928529T2 (de) 1998-04-16
IS3505A7 (is) 1990-03-17
AU4134989A (en) 1990-04-05
CA1340577C (en) 1999-06-01
DK175694B1 (da) 2005-01-24

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