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GB9117175D0 - 13-dihydro-3'-(2-alkoxy-4-morpholinyl)anthracyclines - Google Patents

13-dihydro-3'-(2-alkoxy-4-morpholinyl)anthracyclines

Info

Publication number
GB9117175D0
GB9117175D0 GB919117175A GB9117175A GB9117175D0 GB 9117175 D0 GB9117175 D0 GB 9117175D0 GB 919117175 A GB919117175 A GB 919117175A GB 9117175 A GB9117175 A GB 9117175A GB 9117175 D0 GB9117175 D0 GB 9117175D0
Authority
GB
United Kingdom
Prior art keywords
anthracyclines
morpholinyl
dihydro
alkoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB919117175A
Other versions
GB2247885A (en
GB2247885B (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Farmitalia Carlo Erba SRL
Carlo Erba SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmitalia Carlo Erba SRL, Carlo Erba SpA filed Critical Farmitalia Carlo Erba SRL
Publication of GB9117175D0 publication Critical patent/GB9117175D0/en
Publication of GB2247885A publication Critical patent/GB2247885A/en
Application granted granted Critical
Publication of GB2247885B publication Critical patent/GB2247885B/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/24Condensed ring systems having three or more rings
    • C07H15/252Naphthacene radicals, e.g. daunomycins, adriamycins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/24Heterocyclic radicals containing oxygen or sulfur as ring hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
GB9117175A 1990-09-12 1991-08-08 13-Dihydro-3'-(2-alkoxy-4-morpholinyl)anthracyclines Expired - Lifetime GB2247885B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909019933A GB9019933D0 (en) 1990-09-12 1990-09-12 13-dihydro-3'-(2-alkoxy-4-morphlinyl)anthracyclines

Publications (3)

Publication Number Publication Date
GB9117175D0 true GB9117175D0 (en) 1991-09-25
GB2247885A GB2247885A (en) 1992-03-18
GB2247885B GB2247885B (en) 1994-02-09

Family

ID=10682082

Family Applications (2)

Application Number Title Priority Date Filing Date
GB909019933A Pending GB9019933D0 (en) 1990-09-12 1990-09-12 13-dihydro-3'-(2-alkoxy-4-morphlinyl)anthracyclines
GB9117175A Expired - Lifetime GB2247885B (en) 1990-09-12 1991-08-08 13-Dihydro-3'-(2-alkoxy-4-morpholinyl)anthracyclines

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GB909019933A Pending GB9019933D0 (en) 1990-09-12 1990-09-12 13-dihydro-3'-(2-alkoxy-4-morphlinyl)anthracyclines

Country Status (4)

Country Link
JP (1) JP3068258B2 (en)
DE (1) DE4126475B4 (en)
GB (2) GB9019933D0 (en)
IT (1) IT1251158B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8742076B2 (en) 2008-02-01 2014-06-03 Genentech, Inc. Nemorubicin metabolite and analog reagents, antibody-drug conjugates and methods
WO2010009124A2 (en) 2008-07-15 2010-01-21 Genentech, Inc. Anthracycline derivative conjugates, process for their preparation and their use as antitumor compounds
RU2563638C2 (en) 2010-12-02 2015-09-20 НЕРВИАНО МЕДИКАЛ САЙЕНСИЗ С.р.л. Method of obtaining morpholinylanthracycline derivatives
RU2666356C2 (en) * 2013-04-29 2018-09-07 НЕРВИАНО МЕДИКАЛ САЙЕНСИЗ С.р.л. New morpholinyl anthracycline derivatives

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4464529A (en) * 1982-07-20 1984-08-07 Sri International Analogues of morpholinyl daunorubicin and morpholinyl doxorubicin
JPS59212499A (en) * 1983-05-13 1984-12-01 アドリヤ・ラボラトリ−ズ・インコ−ポレ−テツド 4-demethoxy-3'-deamino-3'(4-morpholinyl) derivative
GB2172594B (en) * 1985-03-22 1988-06-08 Erba Farmitalia New morpholino derivatives of daunorubicin and doxorubicin
GB8905668D0 (en) * 1989-03-13 1989-04-26 Erba Carlo Spa New 3'-(4-morpholinyl)-and 3'-(2-methoxy-4-morpholinyl)-anthracycline derivatives

Also Published As

Publication number Publication date
GB2247885A (en) 1992-03-18
DE4126475B4 (en) 2005-09-15
ITMI912222A0 (en) 1991-08-07
GB2247885B (en) 1994-02-09
JP3068258B2 (en) 2000-07-24
JPH04247096A (en) 1992-09-03
ITMI912222A1 (en) 1992-03-13
DE4126475A1 (en) 1992-03-19
IT1251158B (en) 1995-05-04
GB9019933D0 (en) 1990-10-24

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Legal Events

Date Code Title Description
PE20 Patent expired after termination of 20 years

Expiry date: 20110807