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GB733459A - Process for preparing stimulating agents for clinical use from bacterial polysaccharides - Google Patents

Process for preparing stimulating agents for clinical use from bacterial polysaccharides

Info

Publication number
GB733459A
GB733459A GB14053/53A GB1405353A GB733459A GB 733459 A GB733459 A GB 733459A GB 14053/53 A GB14053/53 A GB 14053/53A GB 1405353 A GB1405353 A GB 1405353A GB 733459 A GB733459 A GB 733459A
Authority
GB
United Kingdom
Prior art keywords
polysaccharides
bacteria
pyridine
stimulating agents
coli
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB14053/53A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wander AG
Original Assignee
Wander AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wander AG filed Critical Wander AG
Publication of GB733459A publication Critical patent/GB733459A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Pyrogenic polysaccharides derived from gramnegative bacteria are acylated, e.g. with an organic acid anhydride. The dried bacteria containing such polysaccharides and preextracted with a solvent for lipoids may replace the polysaccharides themselves. The products are stated to be useful as stimulating agents for the pituitary-adreno-cortical system with only very negligible p side-effects. To minimise side-effects, acylation should continue for at least five hours. Examples describe the treatment of a pyrogenic coli polysaccharide with acetic or propionic anhydride in pyridine and water or in pyridine and formamide, and also the extraction of coli bacteria with chloroform and ethanol, acylation with acetic anhydride in pyridine and water, and further extraction with chloroform and ethanol. Polysaccharides from other bacteria than coli bacteria are referred to.
GB14053/53A 1952-05-21 1953-05-19 Process for preparing stimulating agents for clinical use from bacterial polysaccharides Expired GB733459A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH733459X 1952-05-21

Publications (1)

Publication Number Publication Date
GB733459A true GB733459A (en) 1955-07-13

Family

ID=4532534

Family Applications (1)

Application Number Title Priority Date Filing Date
GB14053/53A Expired GB733459A (en) 1952-05-21 1953-05-19 Process for preparing stimulating agents for clinical use from bacterial polysaccharides

Country Status (1)

Country Link
GB (1) GB733459A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3534983A (en) * 1968-08-02 1970-10-20 Joseph R Alvey Elevatable fifth wheel
WO2003080678A1 (en) * 2002-03-26 2003-10-02 Chiron Srl Modified saccharides having improved stability in water

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3534983A (en) * 1968-08-02 1970-10-20 Joseph R Alvey Elevatable fifth wheel
WO2003080678A1 (en) * 2002-03-26 2003-10-02 Chiron Srl Modified saccharides having improved stability in water

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