GB597889A - The manufacture of 2-amino-5-methyl pyrazine - Google Patents
The manufacture of 2-amino-5-methyl pyrazineInfo
- Publication number
- GB597889A GB597889A GB25496/44A GB2549644A GB597889A GB 597889 A GB597889 A GB 597889A GB 25496/44 A GB25496/44 A GB 25496/44A GB 2549644 A GB2549644 A GB 2549644A GB 597889 A GB597889 A GB 597889A
- Authority
- GB
- United Kingdom
- Prior art keywords
- methylpyrazine
- amino
- manufacture
- carboxy
- reacting
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/20—Nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
2-Amino-5-methylpyrazine is prepared by reacting an alkali metal hypochlorite or hypobromite with aqueous 2 - carboxyamido - 5 - methylpyrazine, which may be prepared by esterifying 2-carboxy-5-methylpyrazine with a lower alcohol and then reacting with anhydrous ammonia. The amino compound may be extracted from the reaction products after they have been made strongly alkaline. In an example, 2-carboxy-5-methylpyrazine is esterified with methyl alcohol, the ester reacted with anhydrous ammonia and the resulting amide added to an aqueous solution of potassium hydroxide and chlorine to yield 2-amino-5-methylpyrazine.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US597889XA | 1943-12-10 | 1943-12-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB597889A true GB597889A (en) | 1948-02-05 |
Family
ID=22025220
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB25496/44A Expired GB597889A (en) | 1943-12-10 | 1944-12-19 | The manufacture of 2-amino-5-methyl pyrazine |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB597889A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3452014A (en) * | 1964-08-14 | 1969-06-24 | Upjohn Co | 2,5-dimethylpyrazine p-toluenesulfonate |
-
1944
- 1944-12-19 GB GB25496/44A patent/GB597889A/en not_active Expired
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3452014A (en) * | 1964-08-14 | 1969-06-24 | Upjohn Co | 2,5-dimethylpyrazine p-toluenesulfonate |
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