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GB452447A - The production of acyl derivatives of germinal gland hormone preparations - Google Patents

The production of acyl derivatives of germinal gland hormone preparations

Info

Publication number
GB452447A
GB452447A GB5735/35A GB573535A GB452447A GB 452447 A GB452447 A GB 452447A GB 5735/35 A GB5735/35 A GB 5735/35A GB 573535 A GB573535 A GB 573535A GB 452447 A GB452447 A GB 452447A
Authority
GB
United Kingdom
Prior art keywords
acyl derivatives
germinal gland
production
methyldiol
gland hormone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB5735/35A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Schering Kahlbaum AG
Original Assignee
Schering Kahlbaum AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Kahlbaum AG filed Critical Schering Kahlbaum AG
Publication of GB452447A publication Critical patent/GB452447A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J9/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J75/00Processes for the preparation of steroids in general

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Acyl derivatives of germinal gland hormones are prepared by hydrogenating esters of unsaturated compounds of similar chemical configuration to the female germinal gland hormone but containing in their ring skeleton directly connected to the carbon atoms thereof two hydroxyl groups and also at least two hydrocarbon residues. Mono acyl compounds prepared in the above manner may be converted into di-acyl compounds by further acylation. The preferred method of hydrogenation is the catalytic method, but other methods may be used. In an example the 3-acetoxy-methyldiol produced by acylation of the compound prepared according to example 1 of Specification 446,501 is hydrogenated in the presence of a platinum oxide catalyst according to the method of Adams-Schriner. On evaporation of the reaction solution the corresponding 3-acetoxyhexahydro-methyldiol is obtained. Specification 434,390 is referred to.
GB5735/35A 1934-02-22 1935-02-22 The production of acyl derivatives of germinal gland hormone preparations Expired GB452447A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE452447X 1934-02-22

Publications (1)

Publication Number Publication Date
GB452447A true GB452447A (en) 1936-08-24

Family

ID=6538655

Family Applications (1)

Application Number Title Priority Date Filing Date
GB5735/35A Expired GB452447A (en) 1934-02-22 1935-02-22 The production of acyl derivatives of germinal gland hormone preparations

Country Status (1)

Country Link
GB (1) GB452447A (en)

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