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GB1436970A - 2-aminoindane derivatives - Google Patents

2-aminoindane derivatives

Info

Publication number
GB1436970A
GB1436970A GB897474A GB897474A GB1436970A GB 1436970 A GB1436970 A GB 1436970A GB 897474 A GB897474 A GB 897474A GB 897474 A GB897474 A GB 897474A GB 1436970 A GB1436970 A GB 1436970A
Authority
GB
United Kingdom
Prior art keywords
formula
radical
represent
phenyl
aminoindane
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB897474A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MANUF PROD PHARMA
Original Assignee
MANUF PROD PHARMA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MANUF PROD PHARMA filed Critical MANUF PROD PHARMA
Priority to GB897474A priority Critical patent/GB1436970A/en
Publication of GB1436970A publication Critical patent/GB1436970A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

1436970 2-Aminoindane derivatives MANUFACTURE DE PRODUITS PHARMACEUTIQUES A. CHRISTIAENS SA 1 March 1974 [1 March 1973] 8974/74 Divided out of 1405444 Heading C2C Compounds of Formula I wherein n is equal to 2 or 3, the (CH 2 ) n group having a straight or branched chain, R 1 and R 2 represent a lower alkyl radical containing 1 to 3 carbon atoms, whereby R 1 and R 2 may also form together with the adjacent nitrogen atom a nitrogenous heterocyclic ring, A is an unsubstituted phenyl radical or a phenyl radical substituted by at least one substituent selected from Cl, OH or C 1-3 alkoxy in the ortho, meta and/or para position of the phenyl radical and B represents hydrogen, an alkoxy radical containing 1 to 3 carbon atoms or a group of the formula in which R 3 and R 4 which may be identical or different represent a C 1-3 alkyl or C 1-3 hydroxyalkyl radical, whereby R 3 may also represent hydrogen, whereas R 3 and R 4 may also form with the attached nitrogen atom a nitrogenous heterocyclic ring, as well as the acid addition salts of said compounds, are prepared by the two following step process:- reaction of a N- phenyl-2-aminoindane of the formula with a bromoehloroalkane Br(CH 2 ) n Cl to give a compound of Formula IV which is optionally isolated or reacted as such with the amine R 1 NHR 2 . Reference has been directed by the Comptroller to Specification 1,321,424.
GB897474A 1973-03-01 1973-03-01 2-aminoindane derivatives Expired GB1436970A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB897474A GB1436970A (en) 1973-03-01 1973-03-01 2-aminoindane derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB897474A GB1436970A (en) 1973-03-01 1973-03-01 2-aminoindane derivatives

Publications (1)

Publication Number Publication Date
GB1436970A true GB1436970A (en) 1976-05-26

Family

ID=9862903

Family Applications (1)

Application Number Title Priority Date Filing Date
GB897474A Expired GB1436970A (en) 1973-03-01 1973-03-01 2-aminoindane derivatives

Country Status (1)

Country Link
GB (1) GB1436970A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2600332A1 (en) * 1986-06-19 1987-12-24 Squibb & Sons Inc P-AMINOPHENOLS AND DERIVATIVES WITH THERAPEUTIC ACTION

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2600332A1 (en) * 1986-06-19 1987-12-24 Squibb & Sons Inc P-AMINOPHENOLS AND DERIVATIVES WITH THERAPEUTIC ACTION
GB2191999A (en) * 1986-06-19 1987-12-31 Squibb & Sons Inc p-Aminophenols, derivatives thereof and method of use

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Legal Events

Date Code Title Description
PS Patent sealed
PS Patent sealed

Free format text: DELETE IN JOURNAL 4573 PAGE 3479

PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee