[go: up one dir, main page]

FR3087659B1 - Dispositif miniaturise de fabrication automatisee de compositions pharmaceutiques, et procede associes - Google Patents

Dispositif miniaturise de fabrication automatisee de compositions pharmaceutiques, et procede associes Download PDF

Info

Publication number
FR3087659B1
FR3087659B1 FR1859870A FR1859870A FR3087659B1 FR 3087659 B1 FR3087659 B1 FR 3087659B1 FR 1859870 A FR1859870 A FR 1859870A FR 1859870 A FR1859870 A FR 1859870A FR 3087659 B1 FR3087659 B1 FR 3087659B1
Authority
FR
France
Prior art keywords
pharmaceutical compositions
automated manufacturing
associated process
miniaturized device
mixing vessel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR1859870A
Other languages
English (en)
Other versions
FR3087659A1 (fr
Inventor
Josselin Saunier
Robert Ronnback
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ferring BV
Original Assignee
Ferring BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR1859870A priority Critical patent/FR3087659B1/fr
Application filed by Ferring BV filed Critical Ferring BV
Priority to TW108138621A priority patent/TWI874329B/zh
Priority to KR1020217015122A priority patent/KR20210084513A/ko
Priority to CN201980070142.6A priority patent/CN112969525A/zh
Priority to US17/287,802 priority patent/US20210308642A1/en
Priority to BR112021007578-0A priority patent/BR112021007578A2/pt
Priority to ARP190103086A priority patent/AR116856A1/es
Priority to EP19790234.9A priority patent/EP3870350A1/fr
Priority to JP2021523054A priority patent/JP7470113B2/ja
Priority to AU2019365493A priority patent/AU2019365493A1/en
Priority to CA3117270A priority patent/CA3117270C/fr
Priority to EA202191092A priority patent/EA202191092A1/ru
Priority to MX2021004522A priority patent/MX2021004522A/es
Priority to PCT/EP2019/079311 priority patent/WO2020084159A1/fr
Publication of FR3087659A1 publication Critical patent/FR3087659A1/fr
Application granted granted Critical
Publication of FR3087659B1 publication Critical patent/FR3087659B1/fr
Priority to IL282520A priority patent/IL282520A/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/80—Mixing plants; Combinations of mixers
    • B01F33/84—Mixing plants with mixing receptacles receiving material dispensed from several component receptacles, e.g. paint tins
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/40—Mixing liquids with liquids; Emulsifying
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/50—Mixing liquids with solids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/80—After-treatment of the mixture
    • B01F23/808—Filtering the mixture
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F27/00—Mixers with rotary stirring devices in fixed receptacles; Kneaders
    • B01F27/80—Mixers with rotary stirring devices in fixed receptacles; Kneaders with stirrers rotating about a substantially vertical axis
    • B01F27/88—Mixers with rotary stirring devices in fixed receptacles; Kneaders with stirrers rotating about a substantially vertical axis with a separate receptacle-stirrer unit that is adapted to be coupled to a drive mechanism
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F29/00—Mixers with rotating receptacles
    • B01F29/15—Use of centrifuges for mixing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
    • B01F31/20—Mixing the contents of independent containers, e.g. test tubes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/45—Magnetic mixers; Mixers with magnetically driven stirrers
    • B01F33/452—Magnetic mixers; Mixers with magnetically driven stirrers using independent floating stirring elements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/80—Mixing plants; Combinations of mixers
    • B01F33/84—Mixing plants with mixing receptacles receiving material dispensed from several component receptacles, e.g. paint tins
    • B01F33/844—Mixing plants with mixing receptacles receiving material dispensed from several component receptacles, e.g. paint tins with means for customizing the mixture on the point of sale, e.g. by sensing, receiving or analysing information about the characteristics of the mixture to be made
    • B01F33/8442—Mixing plants with mixing receptacles receiving material dispensed from several component receptacles, e.g. paint tins with means for customizing the mixture on the point of sale, e.g. by sensing, receiving or analysing information about the characteristics of the mixture to be made using a computer for controlling information and converting it in a formula and a set of operation instructions, e.g. on the point of sale
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/80—Mixing plants; Combinations of mixers
    • B01F33/84—Mixing plants with mixing receptacles receiving material dispensed from several component receptacles, e.g. paint tins
    • B01F33/848—Mixing plants with mixing receptacles receiving material dispensed from several component receptacles, e.g. paint tins using data, i.e. barcodes, 3D codes or similar type of tagging information, as instruction or identification codes for controlling the dispensing and mixing operations
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/10—Maintenance of mixers
    • B01F35/145—Washing or cleaning mixers not provided for in other groups in this subclass; Inhibiting build-up of material on machine parts using other means
    • B01F35/146—Working under sterile conditions; Sterilizing the mixer or parts thereof
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/181—Preventing generation of dust or dirt; Sieves; Filters
    • B01F35/187—Preventing generation of dust or dirt; Sieves; Filters using filters in mixers, e.g. during venting
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/20—Measuring; Control or regulation
    • B01F35/21—Measuring
    • B01F35/211—Measuring of the operational parameters
    • B01F35/2117—Weight
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/20—Measuring; Control or regulation
    • B01F35/21—Measuring
    • B01F35/2132—Concentration, pH, pOH, p(ION) or oxygen-demand
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/20—Measuring; Control or regulation
    • B01F35/22—Control or regulation
    • B01F35/2201—Control or regulation characterised by the type of control technique used
    • B01F35/2202—Controlling the mixing process by feed-back, i.e. a measured parameter of the mixture is measured, compared with the set-value and the feed values are corrected
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/20—Measuring; Control or regulation
    • B01F35/22—Control or regulation
    • B01F35/2201—Control or regulation characterised by the type of control technique used
    • B01F35/2209—Controlling the mixing process as a whole, i.e. involving a complete monitoring and controlling of the mixing process during the whole mixing cycle
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/20—Measuring; Control or regulation
    • B01F35/22—Control or regulation
    • B01F35/221—Control or regulation of operational parameters, e.g. level of material in the mixer, temperature or pressure
    • B01F35/2218—Weight of at least one component to be mixed
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/40—Mounting or supporting mixing devices or receptacles; Clamping or holding arrangements therefor
    • B01F35/41—Mounting or supporting stirrer shafts or stirrer units on receptacles
    • B01F35/412—Mounting or supporting stirrer shafts or stirrer units on receptacles by supporting both extremities of the shaft
    • B01F35/4122—Mounting or supporting stirrer shafts or stirrer units on receptacles by supporting both extremities of the shaft at the side walls of the receptacle
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/80—Forming a predetermined ratio of the substances to be mixed
    • B01F35/88—Forming a predetermined ratio of the substances to be mixed by feeding the materials batchwise
    • B01F35/881—Forming a predetermined ratio of the substances to be mixed by feeding the materials batchwise by weighing, e.g. with automatic discharge
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/90—Heating or cooling systems
    • B01F35/92—Heating or cooling systems for heating the outside of the receptacle, e.g. heated jackets or burners
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F2101/00—Mixing characterised by the nature of the mixed materials or by the application field
    • B01F2101/22—Mixing of ingredients for pharmaceutical or medical compositions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F2101/00—Mixing characterised by the nature of the mixed materials or by the application field
    • B01F2101/2202—Mixing compositions or mixers in the medical or veterinary field

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Accessories For Mixers (AREA)
  • Mixers With Rotating Receptacles And Mixers With Vibration Mechanisms (AREA)
  • Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)
  • Medicinal Preparation (AREA)

Abstract

La présente invention concerne un dispositif (60) de fabrication de compositions pharmaceutiques, comprenant: un support (62); un récipient de mélange (16); une pluralité de réservoirs (18, 20) contenant des produits de départ entrant dans la composition d'un médicament ; au moins un dispositif de distribution (64, 66) apte à distribuer une quantité d'un produit de départ dans le récipient de mélange, ledit dispositif de distribution étant assemblé ou apte à être assemblé à un réservoir ; un dispositif d'agitation (68), apte à agiter le récipient de mélange et/ou un contenu dudit récipient de mélange ; et un module électronique (74) de commande de l'au moins un dispositif de distribution.
FR1859870A 2018-10-25 2018-10-25 Dispositif miniaturise de fabrication automatisee de compositions pharmaceutiques, et procede associes Active FR3087659B1 (fr)

Priority Applications (15)

Application Number Priority Date Filing Date Title
FR1859870A FR3087659B1 (fr) 2018-10-25 2018-10-25 Dispositif miniaturise de fabrication automatisee de compositions pharmaceutiques, et procede associes
CA3117270A CA3117270C (fr) 2018-10-25 2019-10-25 Dispositif miniaturise de fabrication automatisee de compositions pharmaceutiques, et procede associes
CN201980070142.6A CN112969525A (zh) 2018-10-25 2019-10-25 用于自动化制造药物组合物的微型化装置以及相关方法
US17/287,802 US20210308642A1 (en) 2018-10-25 2019-10-25 Miniaturised device for automated manufacture of pharmaceutical compositions, and associated method
BR112021007578-0A BR112021007578A2 (pt) 2018-10-25 2019-10-25 dispositivo miniaturizado para o fabrico automatizado de composições farmacêuticas e método associado
ARP190103086A AR116856A1 (es) 2018-10-25 2019-10-25 Dispositivo miniaturizado para la fabricación automatizada de composiciones farmacéuticas y método asociado
EP19790234.9A EP3870350A1 (fr) 2018-10-25 2019-10-25 Dispositif miniaturisé de fabrication automatisée de compositions pharmaceutiques, et procédé associés
JP2021523054A JP7470113B2 (ja) 2018-10-25 2019-10-25 医薬組成物の自動製造用の小型デバイス及び関連方法
TW108138621A TWI874329B (zh) 2018-10-25 2019-10-25 用於自動化製備醫藥組合物之微型化裝置及相關方法
KR1020217015122A KR20210084513A (ko) 2018-10-25 2019-10-25 약제 조성물의 자동 제조를 위한 소형화된 장치, 및 연관된 방법
EA202191092A EA202191092A1 (ru) 2018-10-25 2019-10-25 Миниатюризированное устройство для автоматического изготовления фармацевтических композиций и связанный способ
MX2021004522A MX2021004522A (es) 2018-10-25 2019-10-25 Dispositivo miniaturizado para fabricacion automatica de composiciones farmaceuticas, y procedimiento asociado.
PCT/EP2019/079311 WO2020084159A1 (fr) 2018-10-25 2019-10-25 Dispositif miniaturisé de fabrication automatisée de compositions pharmaceutiques, et procédé associés
AU2019365493A AU2019365493A1 (en) 2018-10-25 2019-10-25 Miniaturised device for automated manufacture of pharmaceutical compositions, and associated method
IL282520A IL282520A (en) 2018-10-25 2021-04-21 A miniaturized device for the automatic production of pharmaceutical preparations and a related method

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR1859870A FR3087659B1 (fr) 2018-10-25 2018-10-25 Dispositif miniaturise de fabrication automatisee de compositions pharmaceutiques, et procede associes

Publications (2)

Publication Number Publication Date
FR3087659A1 FR3087659A1 (fr) 2020-05-01
FR3087659B1 true FR3087659B1 (fr) 2021-03-05

Family

ID=65444081

Family Applications (1)

Application Number Title Priority Date Filing Date
FR1859870A Active FR3087659B1 (fr) 2018-10-25 2018-10-25 Dispositif miniaturise de fabrication automatisee de compositions pharmaceutiques, et procede associes

Country Status (14)

Country Link
US (1) US20210308642A1 (fr)
EP (1) EP3870350A1 (fr)
JP (1) JP7470113B2 (fr)
KR (1) KR20210084513A (fr)
CN (1) CN112969525A (fr)
AR (1) AR116856A1 (fr)
AU (1) AU2019365493A1 (fr)
BR (1) BR112021007578A2 (fr)
CA (1) CA3117270C (fr)
EA (1) EA202191092A1 (fr)
FR (1) FR3087659B1 (fr)
IL (1) IL282520A (fr)
MX (1) MX2021004522A (fr)
WO (1) WO2020084159A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113546536B (zh) * 2021-07-28 2022-09-06 吉林隆源农业服务有限公司 一种防沉积的高塔复合肥生产用料浆环流式乳化装置
KR102717805B1 (ko) * 2022-03-22 2024-10-15 한국기계연구원 전자동 화합물 합성 장치 및 이를 이용한 화합물 합성 방법
CN114733388B (zh) * 2022-04-22 2022-12-30 安徽金兄弟环保科技股份有限公司 一种污泥回填剂原料混合加工装置
CN118988121B (zh) * 2024-10-25 2024-12-20 南通市肿瘤医院（南通市第五人民医院） 一种化疗药物处理用的调配装置

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5822401B2 (ja) * 1979-10-25 1983-05-09 株式会社 東京商会 自動分包装置
JPH029891Y2 (fr) * 1985-09-28 1990-03-12
JPS6451131A (en) * 1987-08-21 1989-02-27 Fuji Denki Seisakusho Kk Method and apparatus for stirring and mixing fluids
JPH0921687A (ja) * 1995-07-03 1997-01-21 Toyoyoshi Watanabe 重量の秤量を伴う配合あるいは混合のための秤量装置
JPH0933538A (ja) * 1995-07-19 1997-02-07 Toa Medical Electronics Co Ltd 試薬調製装置およびその方法
FR2856940B1 (fr) * 2003-07-04 2007-02-09 Stedim Sa Systeme clos a usage unique de melange, de stockage et d'homogeneisation de liquides en conditions propres ou steriles
NL1026375C1 (nl) * 2004-06-10 2005-12-14 Medical Dispensing Systems V O Werkwijze en inrichting voor het bereiden van preparaten.
WO2006069361A2 (fr) 2004-12-22 2006-06-29 Intelligent Hospital Systems Ltd. Systeme de melange de pharmacie automatise (apas)
FR2932085B1 (fr) * 2008-06-06 2012-08-10 Pharmed Sam Station de travail automatisee pour la preparation securisee d'un produit final a usage medical ou pharmaceutique
JP2010022579A (ja) 2008-07-18 2010-02-04 Shimadzu Corp 自動調剤装置及び調剤システム
US9138693B2 (en) * 2011-03-22 2015-09-22 Salah M. Aouad Automated high precision solution preparation apparatus
FR2957533B1 (fr) * 2010-03-17 2012-09-14 Assistance Et Service Specialise En Innovation Scient Et Tech Dispositif de dosage et de melange controles de plusieurs substances liquides actives
SG10201502122TA (en) * 2011-06-17 2015-05-28 Kiro Robotics Sl Machine And Method For The Automatic Preparation Of Intravenous Medication
JP6106846B2 (ja) 2012-12-13 2017-04-05 パナソニックＩｐマネジメント株式会社 薬剤混合方法
US9364394B2 (en) * 2014-03-14 2016-06-14 Deka Products Limited Partnership Compounder apparatus
DK3254165T3 (da) * 2015-02-06 2021-08-02 Labminds Ltd Automatiseret opløsningsdispenser
CN108025271A (zh) * 2015-09-22 2018-05-11 费森尤斯卡比德国有限公司 配制药物制剂的方法和装置

Also Published As

Publication number Publication date
BR112021007578A2 (pt) 2021-07-27
US20210308642A1 (en) 2021-10-07
JP2022505962A (ja) 2022-01-14
EA202191092A1 (ru) 2021-07-19
CN112969525A (zh) 2021-06-15
TW202031232A (zh) 2020-09-01
FR3087659A1 (fr) 2020-05-01
CA3117270A1 (fr) 2020-04-30
MX2021004522A (es) 2021-07-16
JP7470113B2 (ja) 2024-04-17
WO2020084159A1 (fr) 2020-04-30
EP3870350A1 (fr) 2021-09-01
AR116856A1 (es) 2021-06-23
AU2019365493A1 (en) 2021-06-03
KR20210084513A (ko) 2021-07-07
CA3117270C (fr) 2023-11-14
IL282520A (en) 2021-06-30

Similar Documents

Publication Publication Date Title
FR3087659B1 (fr) Dispositif miniaturise de fabrication automatisee de compositions pharmaceutiques, et procede associes
Williams et al. Mechanochemical organocatalysis: do high enantioselectivities contradict what we might expect?
US20050247742A1 (en) Metering and dispensing closure
WO2012128603A1 (fr) Dispositif automatique et procede de preparation de solutions
ATE539004T1 (de) Abgabekapsel für einen flüssigkeitsbehälter
EP1356866A3 (fr) Système et procédé automatisé pour la préparation de formulation de fluides à haute viscosité
FR2403471A1 (fr) Pompe a piston pour remplir des gelules dures avec un liquide
UA91373C2 (ru) Аппарат для дозирования и смешивания жидкостей
FR3046359B1 (fr) Procede et dispositif pour la fabrication d'un produit personnalise par melange avec capsules
FR3078626B1 (fr) Dispositif d'elaboration d'une dose d'un medicament, a la demande
FR2560072B1 (fr) Dispositif d'actionnement auto-nettoyant pour la distribution de liquides contenant des solides en particules depuis un recipient sous pression ou au moyen d'une pompe a piston.
BE832400A (fr) Dispositif pour injecter des liquides, en particulier une solution de lavage, dans des recipients contenant des matieres solides
TWI537054B (zh) Automatic feeding device
CN206008524U (zh) 污水处理用高精度配药系统
ATE321728T1 (de) Dosiersystem
EP2236199A3 (fr) Processus et installation pour le dosage et mélange automatique et stérile d'infusions
Li et al. Solubility measurement and calculation of difenoconazole in several solvents at 278.15 to 323.15 K
FR2400708A1 (fr) Moyen permettant la preparation de solutions temoins liquides
CN109999695A (zh) 一种果树病虫害防治用农药精量配制装置
CN109455801B (zh) 一种固体二氧化氯消毒设备
ATE456319T1 (de) Insbesondere als dosierpender ausgebildeter spender und spendereinheit zum einsetzen in den spender
CN1471835A (zh) 生产含有少量活性物质的疏松材料的方法
ITVI20060214A1 (it) Coperchio per recipienti e contenitore utilizzante tale coperchio
CN221889618U (zh) 一种畜牧用配药器
DE602004028585D1 (de) Verpackung für Arzneimittel

Legal Events

Date Code Title Description
PLFP Fee payment

Year of fee payment: 2

PLSC Publication of the preliminary search report

Effective date: 20200501

PLFP Fee payment

Year of fee payment: 3

PLFP Fee payment

Year of fee payment: 4

PLFP Fee payment

Year of fee payment: 5

PLFP Fee payment

Year of fee payment: 6

PLFP Fee payment

Year of fee payment: 7