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FR2574800B1 - Procede et separation de la lactoferrine bovine du lait de vache et sa purification - Google Patents

Procede et separation de la lactoferrine bovine du lait de vache et sa purification

Info

Publication number
FR2574800B1
FR2574800B1 FR8518779A FR8518779A FR2574800B1 FR 2574800 B1 FR2574800 B1 FR 2574800B1 FR 8518779 A FR8518779 A FR 8518779A FR 8518779 A FR8518779 A FR 8518779A FR 2574800 B1 FR2574800 B1 FR 2574800B1
Authority
FR
France
Prior art keywords
purification
separation
cow milk
bovine lactoferrin
lactoferrin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8518779A
Other languages
English (en)
Other versions
FR2574800A1 (fr
Inventor
Hiroshi Kawakami
Hiroshi Shinmoto
Shunichi Dosako
Kenkichi Ahiko
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Snow Brand Milk Products Co Ltd
Original Assignee
Snow Brand Milk Products Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Snow Brand Milk Products Co Ltd filed Critical Snow Brand Milk Products Co Ltd
Publication of FR2574800A1 publication Critical patent/FR2574800A1/fr
Application granted granted Critical
Publication of FR2574800B1 publication Critical patent/FR2574800B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/79—Transferrins, e.g. lactoferrins, ovotransferrins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/808—Materials and products related to genetic engineering or hybrid or fused cell technology, e.g. hybridoma, monoclonal products
    • Y10S530/809—Fused cells, e.g. hybridoma
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/832—Milk; colostrum

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
FR8518779A 1984-12-19 1985-12-18 Procede et separation de la lactoferrine bovine du lait de vache et sa purification Expired FR2574800B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP59266401A JPS61145200A (ja) 1984-12-19 1984-12-19 ウシラクトフェリンの分離精製法

Publications (2)

Publication Number Publication Date
FR2574800A1 FR2574800A1 (fr) 1986-06-20
FR2574800B1 true FR2574800B1 (fr) 1989-11-17

Family

ID=17430416

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8518779A Expired FR2574800B1 (fr) 1984-12-19 1985-12-18 Procede et separation de la lactoferrine bovine du lait de vache et sa purification

Country Status (8)

Country Link
US (1) US4668771A (fr)
JP (1) JPS61145200A (fr)
AU (1) AU585543B2 (fr)
BE (1) BE903886A (fr)
DE (1) DE3544400A1 (fr)
FR (1) FR2574800B1 (fr)
GB (1) GB2168982B (fr)
NZ (1) NZ213985A (fr)

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE61701B1 (en) * 1986-07-17 1994-11-30 Morinaga Milk Industry Co Ltd Process for producing bovine lactoferrin in high purity
DE3638767A1 (de) * 1986-11-13 1988-05-26 Behringwerke Ag Laktoferrin enthaltendes inkubationsmedium fuer festphasenimmunometrisches verfahren und seine verwendung
CA1339946C (fr) * 1987-03-31 1998-07-07 Michael J. Griffith Methode d'ultrapurification pour les polypeptides
JPH0725800B2 (ja) * 1987-04-10 1995-03-22 雪印乳業株式会社 硫酸エステル化物を用いて乳からラクトフエリンを分離、精製する方法
US5344820A (en) * 1987-05-15 1994-09-06 Snow Brand Milk Products Co., Ltd. Infection protectant
US4977137B1 (en) * 1987-06-03 1994-06-28 Baylor College Medicine Lactoferrin as a dietary ingredient promoting the growth of the gastrointestinal tract
SE458818B (sv) * 1987-11-27 1989-05-16 Svenska Mejeriernas Riksforeni Foerfarande foer utvinning av rena fraktioner av laktoperoxidas och laktoferrin ur mjoelkserum
FR2631785A1 (fr) * 1988-05-27 1989-12-01 Agronomique Inst Nat Rech Procede de fractionnement des proteines du lait humain, conduisant a la production, notamment de lactoferrine et d'(alpha)-lactalbumine, et produits obtenus
NZ230031A (en) * 1988-07-27 1991-10-25 Snow Brand Milk Products Co Ltd Separation of proteins (e.g. lactoferrin) using affinity gel carrier in a rotary column
JP2805490B2 (ja) 1989-02-07 1998-09-30 雪印乳業株式会社 細菌毒素中和剤
JPH0779684B2 (ja) 1989-02-27 1995-08-30 森永乳業株式会社 ビフィズス菌増殖促進組成物
US5639624A (en) * 1989-03-14 1997-06-17 Board Of Regents Of The University Of Nebraska Monoclonal antibodies specific for metallic cations and method therefor
ATE161852T1 (de) * 1989-03-14 1998-01-15 Univ Nebraska Monoklonale antikörper für metall kationen
US5972656A (en) * 1989-03-14 1999-10-26 Bionebraska, Inc. Mercury binding polypeptides and nucleotides coding therefore
US5571691A (en) * 1989-05-05 1996-11-05 Baylor College Of Medicine Production of recombinant lactoferrin and lactoferrin polypeptides using CDNA sequences in various organisms
US5766939A (en) * 1989-05-05 1998-06-16 Baylor College Of Medicine Production of recombinant lactoferrin and lactoferrin polypeptides using CDNA sequences in various organisms
US5849881A (en) * 1989-05-05 1998-12-15 Baylor College Medicine Production of recombinant lactoferrin and lactoferrin polypeptides using cDNA sequences in various organisms
US6100054A (en) * 1989-05-05 2000-08-08 Baylor College Of Medicine Production for recombinant lactoferrin and lactoferrin polypeptides using DNA sequences in various organisms
IL94183A (en) 1989-05-05 2003-09-17 Baylor College Medicine cDNA SEQUENCE CODING FOR HUMAN LACTOFERRIN PROTEIN OR PORTION THEREOF AND LACTOFERRIN PROTEIN PRODUCED FROM SAID SEQUENCE
US5633076A (en) * 1989-12-01 1997-05-27 Pharming Bv Method of producing a transgenic bovine or transgenic bovine embryo
US5573937A (en) * 1989-12-07 1996-11-12 Snow Brand Milk Products Co., Ltd. Serum free culture medium
US5198419A (en) * 1989-12-08 1993-03-30 Immuno Japan Inc. Formulated medicines for enhancing the efficacy of beta-lactam antibiotics in prophylaxis and treatment against infectious disease due to pathogenic bacteria
DE69017921T2 (de) * 1990-01-23 1995-10-12 Morinaga Milk Industry Co. Ltd., Tokio/Tokyo Lactoferrinhydrolysat zur Verwendung als tyrosinagehemmendes Mittel.
US6066469A (en) 1990-03-08 2000-05-23 Ferro Dynamics, Inc. Cloning, expression, and uses of human lactoferrin
US6319522B1 (en) 1990-07-13 2001-11-20 Gropep Limited Growth-promoting agent
US7033610B2 (en) 1990-07-13 2006-04-25 Gropep Pty, Ltd. Growth-promoting agent
CA2086681C (fr) * 1990-07-13 2004-01-06 Francis J. Ballard Agent stimulant la croissance derive du lait
JPH05202098A (ja) * 1992-01-29 1993-08-10 Snow Brand Milk Prod Co Ltd 乳質原料から生理活性物質の製造法
US6096870A (en) * 1994-01-05 2000-08-01 Sepragen Corporation Sequential separation of whey
EP1142484A2 (fr) * 1994-02-16 2001-10-10 Pharming Intellectual Property BV Isolation de la lactoferrine du lait
US6111079A (en) * 1995-06-05 2000-08-29 Bionebraska, Inc. Lead binding polypeptides and nucleotides coding therefore
US6111081A (en) * 1996-05-31 2000-08-29 Baylor College Of Medicine Lactoferrin variants and uses thereof
WO1998004922A1 (fr) * 1996-07-30 1998-02-05 Shionogi & Co., Ltd. Procede permettant d'empecher l'adsorption de lactoferrine
US20040259770A1 (en) * 2003-06-19 2004-12-23 Rush University Medical Center Method for determining leukocyte activation
WO2005041680A2 (fr) * 2003-11-03 2005-05-12 Advanced Protein Systems Nouveau procede de fractionnement du colostrum
US7780873B2 (en) * 2004-02-23 2010-08-24 Texas A&M University System Bioactive complexes compositions and methods of use thereof
WO2005085287A1 (fr) 2004-03-03 2005-09-15 En-N-Tech, Inc. Traitements pour la reduction de contaminants dans des preparations de lactoferrines et compositions contenant des lactoferrines
AU2006233196B2 (en) * 2005-10-28 2012-07-05 Fonterra Co-Operative Group Limited Enriched milk products
US20070212367A1 (en) * 2006-03-13 2007-09-13 Keech Andrew M Novel immunologically active peptide fragments of a proline-rich polypeptide isolated from colostral mammalian fluids for treatment of viral and non-viral diseases or diseased conditions
US20080003329A1 (en) * 2006-06-30 2008-01-03 Ricardo Rueda Enriched infant formulas
EP2173770B1 (fr) 2007-07-10 2015-05-27 Glanbia Nutritionals (Ireland) Limited Procédé d'élimination d'endotoxines de protéines
US9458225B2 (en) * 2013-06-26 2016-10-04 United Arab Emirates University Method for purifying lactoferrin
CN106140099B (zh) * 2015-04-17 2018-10-16 北京美正生物科技有限公司 一种分离纯化乳铁蛋白的免疫亲和柱及其制备方法和用途
JP6082941B2 (ja) * 2016-02-02 2017-02-22 株式会社Ｎｒｌファーマ 更年期障害改善用医薬組成物ならびに飲食物
EP3766354A4 (fr) 2018-03-12 2021-12-15 Morinaga Milk Industry Co., Ltd. Procédé de production d'une solution aqueuse contenant de la lactoferrine
US12263192B2 (en) 2019-02-26 2025-04-01 Pantheryx, Inc. Compositions for management of disorders of the gastrointestinal tract
CN113311155B (zh) * 2021-04-09 2022-11-29 深圳市计量质量检测研究院（国家高新技术计量站、国家数字电子产品质量监督检验中心） 一种牛乳蛋白和水牛乳蛋白二联检测卡的制备方法及应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4229342A (en) * 1977-05-18 1980-10-21 Rhone-Poulenc Industries Process for extracting proteins from milk using silica and anion exchange resins
GB2091739B (en) * 1981-01-27 1984-08-01 Pulblic Helth Lab Service Boar Purification of human growth hormone
FR2505615A1 (fr) * 1981-05-15 1982-11-19 Elf Aquitaine Procede d'extraction de lactoferrine et d'immunoglobulines du lait
JPS59148725A (ja) * 1983-02-14 1984-08-25 Snow Brand Milk Prod Co Ltd 高純度のヒト・トランスフエリンの製法
JPH0686480B2 (ja) * 1983-02-21 1994-11-02 雪印乳業株式会社 エリスロポエチン製造用モノクローナル抗体
JPH0669370B2 (ja) * 1984-07-13 1994-09-07 雪印乳業株式会社 モノクローナル抗ウシラクトフェリン抗体産生ハイブリドーマの製造法

Also Published As

Publication number Publication date
GB2168982A (en) 1986-07-02
DE3544400A1 (de) 1986-06-26
US4668771A (en) 1987-05-26
BE903886A (fr) 1986-04-16
GB8530898D0 (en) 1986-01-29
GB2168982B (en) 1989-02-01
FR2574800A1 (fr) 1986-06-20
JPS61145200A (ja) 1986-07-02
NZ213985A (en) 1989-02-24
JPH0566397B2 (fr) 1993-09-21
AU4922785A (en) 1986-06-26
AU585543B2 (en) 1989-06-22

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Legal Events

Date Code Title Description
ST Notification of lapse