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FR2414920A1 - Interferon et preparation le contenant - Google Patents

Interferon et preparation le contenant

Info

Publication number
FR2414920A1
FR2414920A1 FR7901324A FR7901324A FR2414920A1 FR 2414920 A1 FR2414920 A1 FR 2414920A1 FR 7901324 A FR7901324 A FR 7901324A FR 7901324 A FR7901324 A FR 7901324A FR 2414920 A1 FR2414920 A1 FR 2414920A1
Authority
FR
France
Prior art keywords
interferon
cells
container preparation
animal
viral
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7901324A
Other languages
English (en)
Other versions
FR2414920B1 (fr
Inventor
Kaname Sugimoto
Shokichi Yuen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
HAYASHIBARA KEN
Original Assignee
HAYASHIBARA KEN
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP536878A external-priority patent/JPS5498307A/ja
Priority claimed from JP13402678A external-priority patent/JPS5562024A/ja
Application filed by HAYASHIBARA KEN filed Critical HAYASHIBARA KEN
Publication of FR2414920A1 publication Critical patent/FR2414920A1/fr
Application granted granted Critical
Publication of FR2414920B1 publication Critical patent/FR2414920B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/91—Cell lines ; Processes using cell lines
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/811—Interferon

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Production d'interféron à partir de cellules humaines. Le procédé consiste à multiplier ces cellules dans le corps d'un autre animal à sang chaud, éventuellement par l'intermédiaire d'une chambre de diffusion, le fluide corporel nutritif de l'animal servant à la nourriture des cellules; puis les cellules multipliées sont soumises in vivo ou in vitro à l'action d'un inducteur d'interféron, et celui-ci est recueilli et purifié. L'interféron ainsi produit en grande quantite est de qualité supérieure, et il est utilisable pour le traitement de maladies virales et tumorales.
FR7901324A 1978-01-22 1979-01-19 Interferon et preparation le contenant Granted FR2414920A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP536878A JPS5498307A (en) 1978-01-22 1978-01-22 Production of interferon
JP13402678A JPS5562024A (en) 1978-10-31 1978-10-31 Preventive and remedy for interferon-sensitive disease

Publications (2)

Publication Number Publication Date
FR2414920A1 true FR2414920A1 (fr) 1979-08-17
FR2414920B1 FR2414920B1 (fr) 1982-08-06

Family

ID=26339293

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7901324A Granted FR2414920A1 (fr) 1978-01-22 1979-01-19 Interferon et preparation le contenant

Country Status (14)

Country Link
US (1) US4276282A (fr)
AU (1) AU533201B2 (fr)
CA (1) CA1135186A (fr)
CH (1) CH637831A5 (fr)
DE (1) DE2902136C2 (fr)
DK (1) DK153848C (fr)
ES (1) ES477060A1 (fr)
FI (1) FI66428C (fr)
FR (1) FR2414920A1 (fr)
GB (1) GB2016015B (fr)
IT (1) IT1116493B (fr)
NL (1) NL192086C (fr)
NO (1) NO152976C (fr)
SE (1) SE436969B (fr)

Cited By (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2446637A1 (fr) * 1979-01-18 1980-08-14 Hayashibara Ken Procede pour preparer de l'interferon de type ii et preparations contenant de l'interferon de type ii
FR2487851A1 (fr) * 1980-07-30 1982-02-05 Hayashibara Biochem Lab Procede pour la production d'insuline humaine
FR2487852A1 (fr) * 1980-07-31 1982-02-05 Hayashibara Biochem Lab Production d'hormone de croissance humaine
FR2488805A1 (fr) * 1980-08-23 1982-02-26 Hayashibara Seibutsu Chem Inst Procede pour la production de gonadotrophine chorionique humaine
FR2488804A1 (fr) * 1980-08-22 1982-02-26 Hayashibara Seibutsu Chem Inst Procede pour la production de prolactine humaine
FR2488803A1 (fr) * 1980-08-25 1982-02-26 Hayashibara Ken Procede pour la production d'erythropoietine humaine
FR2489151A1 (fr) * 1980-08-27 1982-03-05 Hayashibara Seibutsu Chem Inst Production d'hormone luteinisante humaine
FR2489152A1 (fr) * 1980-08-27 1982-03-05 Hayashibara Seibutsu Chem Inst Production d'hormone humaine stimulant les follicules
FR2495635A1 (fr) * 1980-12-05 1982-06-11 Hayashibara Biochem Lab Production d'urokinase humaine
FR2495938A1 (fr) * 1980-12-13 1982-06-18 Hayashibara Biochem Lab Procede pour la production d'hormone adrenocorticotrope humaine
FR2495937A1 (fr) * 1980-12-11 1982-06-18 Hayashibara Biochem Lab Procede pour la production du facteur de croissance epidermique humain
FR2496466A1 (fr) * 1980-12-19 1982-06-25 Hayashibara Biochem Lab Production d'hormone lactogene, placentaire, humaine
FR2497103A1 (fr) * 1980-12-31 1982-07-02 Hayashibara Biochem Lab Production de facteur de croissance humain
FR2497100A1 (fr) * 1980-12-30 1982-07-02 Hayashibara Biochem Lab Production de calcitonine humaine
FR2497101A1 (fr) * 1980-12-30 1982-07-02 Hayashibara Seibutsu Chem Inst Production d'hormone stimulation de la thyroide humaine
FR2497102A1 (fr) * 1980-12-30 1982-07-02 Hayashibara Seibutsu Chem Inst Production d'hormone parathyroidienne humaine
FR2513124A1 (fr) * 1981-07-21 1983-03-25 Hayashibara Biochem Lab Production et applications du facteur de lyse des cellules-cibles
FR2521588A1 (fr) * 1982-02-12 1983-08-19 Hayashibara Biochem Lab Procede de production de suppresseur de reponse immunitaire humain

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55122717A (en) * 1979-03-15 1980-09-20 Asai Gerumaniumu Kenkyusho:Kk Interferon inducer
WO1981001102A1 (fr) * 1979-10-19 1981-04-30 A Romano Remede pour le traitement des infections virales de l'oeil et d'autres organes
US4328207A (en) * 1979-12-27 1982-05-04 Ken Hayashibara Process for preparing mouse interferon
US4497796A (en) * 1980-03-26 1985-02-05 The Regents Of The University Of California Gene transfer in intact mammals
US4396601A (en) * 1980-03-26 1983-08-02 The Regents Of The University Of Calif. Gene transfer in intact mammals
US4621053A (en) * 1980-07-30 1986-11-04 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Process for the production of human peptide hormones
US4462985A (en) * 1980-08-22 1984-07-31 University Of Illinois Foundation Delivery of biologically active components of heterologous species interferon isolates
US4364863A (en) * 1980-12-29 1982-12-21 Schering Corporation Extraction of interferon from bacteria
JPS6030654B2 (ja) * 1980-12-31 1985-07-17 株式会社林原生物化学研究所 ヒトコロニ−刺激因子の製造方法
DE3249946C2 (de) * 1981-07-21 1996-03-21 Hayashibara Biochem Lab hTNF-haltiges therapeutisches Mittel gegen maligne Tumoren und dessen Verwendung
WO1983001198A1 (fr) * 1981-10-08 1983-04-14 Kurt Frimann Berg Procede et composition de traitement d'un patient presentant des troubles sensibles a l'interferon
US4675295A (en) * 1981-10-28 1987-06-23 Denki Kagaku Kogyo Kabushiki Kaisha Process for producing subculturable lymphokine-producing human T cell hybridomas
JPS58126786A (ja) * 1982-01-25 1983-07-28 Hayashibara Biochem Lab Inc ヒトカリクレインの製造方法
US4624917A (en) * 1982-02-17 1986-11-25 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Process for the production of human T-cell growth factor
US4987079A (en) * 1982-07-06 1991-01-22 Wilbur D. Smith Composition and method for in vitro cell culture
EP0116631A4 (fr) * 1982-08-10 1986-04-15 Univ Columbia Utilisation de sequences activantes eucaryotiques dans la production de materiaux proteiques.
US5702699A (en) * 1982-09-23 1997-12-30 Cetus Corporation Process for the recovery of lipophilic proteins
US4870009A (en) * 1982-11-22 1989-09-26 The Salk Institute For Biological Studies Method of obtaining gene product through the generation of transgenic animals
US5910304A (en) * 1982-12-13 1999-06-08 Texas A&M University System Low-dose oral administration of interferons
US4820515A (en) * 1982-12-13 1989-04-11 Texas A&M University System Method of using interferon in low dosage to regulate appetite and efficiency of food utilization
JPS59163313A (ja) * 1983-03-09 1984-09-14 Teijin Ltd 経鼻投与用ペプチドホルモン類組成物
US4489163A (en) 1983-04-14 1984-12-18 The Salk Institute For Biological Studies rCRF and analogs
DE3476634D1 (en) * 1983-06-13 1989-03-16 Ragnvald Erik Lindblom A method of treating interferon sensitive diseases, and a method and a device for preparing a _g(g)-interferon containing preparation
US4680174A (en) * 1984-05-24 1987-07-14 Damon Biotech, Inc. Induction of immune response by immunization with encapsulated antigen-producing cells
US5019385A (en) * 1984-11-09 1991-05-28 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Novel lymphopine LK 2 and pharmaceutic compositions containing same
CA1320905C (fr) * 1986-11-06 1993-08-03 Joseph M. Cummins Traitement d'affections immuno-resistantes
ZA878295B (en) * 1986-11-06 1988-05-03 Amarillo Cell Culture Co. Inc. Treatment of immuno-resistant disease
US5175385A (en) * 1987-09-03 1992-12-29 Ohio University/Edison Animal Biotechnolgy Center Virus-resistant transgenic mice
DE3731255A1 (de) * 1987-09-17 1989-04-06 Boehringer Ingelheim Int Stabilisierung von therapeutisch wirksamen proteinen in pharmazeutischen zubereitungen
US5017371A (en) * 1988-01-06 1991-05-21 Amarillo Cell Culture Company, Incorporated Method for reducing side effects of cancer therapy
JPH0665297A (ja) * 1992-08-21 1994-03-08 Hayashibara Biochem Lab Inc メラニン合成抑制蛋白質とその製造方法並びに用途
DE69431320T2 (de) * 1993-04-09 2003-04-17 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo, Okayama Verwendung von menschlichem Interferon-d zur Herstellung eines Arzneimittels zur Behandlung von Atemwegserkrankungen in Katzen
US7135458B1 (en) 1995-11-15 2006-11-14 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Interferon-γ inducing polypeptide, pharmaceutical composition thereof, monoclonal antibody thereto, and methods of use
JP4004088B2 (ja) 1995-09-26 2007-11-07 株式会社林原生物化学研究所 免疫担当細胞においてインターフェロン−γの産生を誘導する蛋白質
US5723718A (en) * 1994-12-20 1998-03-03 St. Joseph's Hospital And Medical Center Induction of immune tolerance to tumor cells
US5939286A (en) * 1995-05-10 1999-08-17 University Of Florida Hybrid interferon tau/alpha polypeptides, their recombinant production, and methods using them
US6204022B1 (en) 1996-04-12 2001-03-20 Pepgen Corporation And University Of Florida Low-toxicity human interferon-alpha analogs
JPH1080270A (ja) * 1996-07-19 1998-03-31 Hayashibara Biochem Lab Inc ポリペプチドをプロセッシングする酵素
TW515843B (en) * 1996-07-25 2003-01-01 Hayashibara Biochem Lab Process for producing an active polypeptide inducing interferon-γ production
EP1013667B1 (fr) * 1998-11-09 2006-10-11 Nippon Biologicals, Inc. Procédé de production de cytokines grâce à un système d'expression de virus sendai
EP1092773A3 (fr) * 1999-10-15 2001-08-08 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Polypeptide et ses utilisations
JP2002201141A (ja) * 2000-10-27 2002-07-16 Hayashibara Biochem Lab Inc 蛋白質合成抑制遺伝子の発現増強剤
EP1425409A4 (fr) * 2001-08-12 2005-11-09 Pepgen Corp Proteines d'interferon hybride/interferon tau, compositions et procedes d'utilisation associes
CA2911613A1 (fr) 2013-03-29 2014-10-02 Centre National De La Recherche Scientifique (Cnrs) Agoniste de recepteur cgrp pour le traitement ou la prevention du vih
WO2015140348A2 (fr) 2014-03-21 2015-09-24 Centre National De La Recherche Scientifique (Cnrs) Utilisation de l'activité de dj-1 déglycase

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2034473A1 (fr) * 1969-01-17 1970-12-11 Merck & Co Inc

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2034473A1 (fr) * 1969-01-17 1970-12-11 Merck & Co Inc

Cited By (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2446637A1 (fr) * 1979-01-18 1980-08-14 Hayashibara Ken Procede pour preparer de l'interferon de type ii et preparations contenant de l'interferon de type ii
FR2487851A1 (fr) * 1980-07-30 1982-02-05 Hayashibara Biochem Lab Procede pour la production d'insuline humaine
FR2487852A1 (fr) * 1980-07-31 1982-02-05 Hayashibara Biochem Lab Production d'hormone de croissance humaine
FR2488804A1 (fr) * 1980-08-22 1982-02-26 Hayashibara Seibutsu Chem Inst Procede pour la production de prolactine humaine
FR2488805A1 (fr) * 1980-08-23 1982-02-26 Hayashibara Seibutsu Chem Inst Procede pour la production de gonadotrophine chorionique humaine
FR2488803A1 (fr) * 1980-08-25 1982-02-26 Hayashibara Ken Procede pour la production d'erythropoietine humaine
FR2489151A1 (fr) * 1980-08-27 1982-03-05 Hayashibara Seibutsu Chem Inst Production d'hormone luteinisante humaine
FR2489152A1 (fr) * 1980-08-27 1982-03-05 Hayashibara Seibutsu Chem Inst Production d'hormone humaine stimulant les follicules
FR2495635A1 (fr) * 1980-12-05 1982-06-11 Hayashibara Biochem Lab Production d'urokinase humaine
FR2495937A1 (fr) * 1980-12-11 1982-06-18 Hayashibara Biochem Lab Procede pour la production du facteur de croissance epidermique humain
FR2495938A1 (fr) * 1980-12-13 1982-06-18 Hayashibara Biochem Lab Procede pour la production d'hormone adrenocorticotrope humaine
FR2496466A1 (fr) * 1980-12-19 1982-06-25 Hayashibara Biochem Lab Production d'hormone lactogene, placentaire, humaine
FR2497100A1 (fr) * 1980-12-30 1982-07-02 Hayashibara Biochem Lab Production de calcitonine humaine
FR2497101A1 (fr) * 1980-12-30 1982-07-02 Hayashibara Seibutsu Chem Inst Production d'hormone stimulation de la thyroide humaine
FR2497102A1 (fr) * 1980-12-30 1982-07-02 Hayashibara Seibutsu Chem Inst Production d'hormone parathyroidienne humaine
FR2497103A1 (fr) * 1980-12-31 1982-07-02 Hayashibara Biochem Lab Production de facteur de croissance humain
FR2513124A1 (fr) * 1981-07-21 1983-03-25 Hayashibara Biochem Lab Production et applications du facteur de lyse des cellules-cibles
FR2521588A1 (fr) * 1982-02-12 1983-08-19 Hayashibara Biochem Lab Procede de production de suppresseur de reponse immunitaire humain

Also Published As

Publication number Publication date
FR2414920B1 (fr) 1982-08-06
NO152976B (no) 1985-09-16
SE7900493L (sv) 1979-07-23
DE2902136C2 (de) 1986-09-04
DE2902136A1 (de) 1979-08-09
NL192086C (nl) 1997-02-04
AU4334579A (en) 1979-08-02
DK153848B (da) 1988-09-12
AU533201B2 (en) 1983-11-10
FI66428B (fi) 1984-06-29
NO152976C (no) 1985-12-27
FI790188A (fi) 1979-07-23
GB2016015A (en) 1979-09-19
GB2016015B (en) 1982-05-06
NL7900476A (nl) 1979-07-24
NL192086B (nl) 1996-10-01
FI66428C (fi) 1984-10-10
DK25579A (da) 1979-07-23
CA1135186A (fr) 1982-11-09
DK153848C (da) 1989-04-03
SE436969B (sv) 1985-02-04
ES477060A1 (es) 1979-12-16
NO790195L (no) 1979-07-24
IT7947712A0 (it) 1979-01-19
IT1116493B (it) 1986-02-10
US4276282A (en) 1981-06-30
CH637831A5 (fr) 1983-08-31

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