FI893170L - Menetelmä uusien terapeuttisesti käyttökelpoisten 1,2,3-triatsolo/4,5-f/kinoksaliinijohdannaisten valmistamiseksi - Google Patents

Menetelmä uusien terapeuttisesti käyttökelpoisten 1,2,3-triatsolo/4,5-f/kinoksaliinijohdannaisten valmistamiseksi Download PDF

Info

Publication number: FI893170L
Authority: FI; Finland
Prior art keywords: triazolo; therapeutically useful; quinoxaline derivatives; preparing novel; novel therapeutically
Prior art date: 1988-06-28

Application number

FI893170A

Other languages

English (en)

Swedish (sv)

Other versions

FI893170A0 (fi

FI91259C (fi

FI91259B (fi

Inventor

Poul Jacobsen

Flemming Elmelund Nielsen

Tage Honore

Joergen Drejer

Original Assignee

Ferrosan As

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-06-28

Filing date

1989-06-28

Publication date

1989-12-29

1989-06-28 Application filed by Ferrosan As filed Critical Ferrosan As

1989-06-28 Publication of FI893170A0 publication Critical patent/FI893170A0/fi

1989-12-29 Publication of FI893170L publication Critical patent/FI893170L/fi

1993-04-27 Priority to FI931893A priority Critical patent/FI93840C/fi

1993-04-27 Priority to FI931891A priority patent/FI93838C/fi

1993-04-27 Priority to FI931894A priority patent/FI93839C/fi

1993-04-27 Priority to FI931892A priority patent/FI93841C/fi

1994-02-28 Application granted granted Critical

1994-02-28 Publication of FI91259B publication Critical patent/FI91259B/fi

1994-06-10 Publication of FI91259C publication Critical patent/FI91259C/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D517/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having selenium, tellurium, or halogen atoms as ring hetero atoms
- C07D517/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having selenium, tellurium, or halogen atoms as ring hetero atoms in which the condensed system contains two hetero rings
- C07D517/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Plural Heterocyclic Compounds (AREA)
Luminescent Compositions (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

FI893170A 1988-06-28 1989-06-28 Menetelmä uusien terapeuttisesti käyttökelpoisten 1,2,3-triatsolo/4,5-f/kinoksaliinijohdannaisten valmistamiseksi FI91259C (fi)

Priority Applications (4)

Application Number	Priority Date	Filing Date	Title
FI931893A FI93840C (fi)	1988-06-28	1993-04-27	Menetelmä uusien terapeuttisesti käyttökelpoisten 7,8-dihydroksi-1,2,5-oksa-, tia- ja seleenidiatsolo/3,4-f/kinoksaliinijohdannaisten valmistamiseksi
FI931891A FI93838C (fi)	1988-06-28	1993-04-27	Menetelmä uusien terapeuttisesti käyttökelpoisten 7,8-dihydroksi-1H-imidatso- ja pyratsolo/3,4-f/kinoksaliinijohdannaisten valmistamiseksi
FI931894A FI93839C (fi)	1988-06-28	1993-04-27	Menetelmä uusien terapeuttisesti käyttökelpoisten 2,3-dihydroksi-pyratsino/2,3-f/kinoksaliini- ja pyratsino/2,3-g//1,5/bentsodiatsepiinijohdannaisten valmistamiseksi
FI931892A FI93841C (fi)	1988-06-28	1993-04-27	Menetelmä uusien terapeuttisesti käyttökelpoisten tiatsolo/5,4-f/- ja tieno/3,2-f/kinoksaliinijohdannaisten valmistamiseksi

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DK356788A DK160941C (da)	1988-06-28	1988-06-28	Kondenserede 2,3-dihydroxypyraziner, fremgangsmaade til deres fremstilling og farmaceutiske praeparater, hvori forbindelserne indgaar
DK356788		1988-06-28

Publications (4)

Publication Number	Publication Date
FI893170A0 FI893170A0 (fi)	1989-06-28
FI893170L true FI893170L (fi)	1989-12-29
FI91259B FI91259B (fi)	1994-02-28
FI91259C FI91259C (fi)	1994-06-10

Family

ID=8124358

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI893170A FI91259C (fi)	1988-06-28	1989-06-28	Menetelmä uusien terapeuttisesti käyttökelpoisten 1,2,3-triatsolo/4,5-f/kinoksaliinijohdannaisten valmistamiseksi

Country Status (18)

Country	Link
US (5)	US4977155A (fi)
EP (1)	EP0348872B1 (fi)
JP (1)	JPH0248578A (fi)
KR (1)	KR910000735A (fi)
AT (1)	ATE95181T1 (fi)
AU (1)	AU619863B2 (fi)
CA (1)	CA1326670C (fi)
DE (1)	DE68909513T2 (fi)
DK (1)	DK160941C (fi)
ES (1)	ES2059636T3 (fi)
FI (1)	FI91259C (fi)
IE (1)	IE64289B1 (fi)
IL (1)	IL90733A (fi)
NO (1)	NO169390C (fi)
NZ (1)	NZ229730A (fi)
PH (1)	PH27565A (fi)
PT (1)	PT91010B (fi)
ZA (1)	ZA894903B (fi)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK716188D0 (da) *	1988-12-22	1988-12-22	Ferrosan As	Quinoxalinforbindelser, deres fremstilling og anvendelse
US5153195A (en) *	1988-12-22	1992-10-06	Novo Nordisk A/S	Quinoxaline compounds and their preparation and use
PT99864B (pt)	1990-12-21	1999-06-30	Schering Ag	Processo para a preparacao de novas composicoes farmaceuticas contendo antagonistas de receptor de quisqualato
US5196421A (en) *	1991-06-05	1993-03-23	Eli Lilly And Company	Excitatory amino acid receptor antagonists in methods for the use thereof
US5153196A (en) *	1991-06-05	1992-10-06	Eli Lilly And Company	Excitatory amino acid receptor antagonists and methods for the use thereof
DK162491D0 (da) *	1991-09-20	1991-09-20	Novo Nordisk As	Heterocycliske forbindelser, deres fremstilling og farmaceutiske praeparater indeholdende forbindelserne
CA2138026C (en) *	1992-06-22	2003-09-09	Eckard Weber	Novel 1,4-dihydroquinoxaline-2,3-diones and uses therefor as glycine receptor antagonists
AU680632B2 (en)	1992-10-13	1997-08-07	Neurosearch A/S	Quinoxalinedione derivatives as EAA antagonists
DE4310523A1 (de) *	1993-03-31	1994-10-06	Basf Ag	Imidazolo-chinoxalinone zur Behandlung zentralnervöser Erkrankungen
US5631373A (en)	1993-11-05	1997-05-20	State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon, Eugene Oregon	Alkyl, azido, alkoxy, and fluoro-substituted and fused quinoxalinediones
US5576323A (en) *	1993-12-03	1996-11-19	Eli Lilly And Company	Excitatory amino acid receptor antagonists
AU688459B2 (en) *	1994-04-08	1998-03-12	Shionogi & Co., Ltd.	Oxopyridinylquinoxaline derivative
US5476851A (en) *	1994-09-08	1995-12-19	Rhone-Poulenc Rorer Pharmaceuticals, Inc.	Pyrazolo[3,4-g]quinoxaline compounds which inhibit PDGF receptor protein tyrosine kinase
US5719153A (en) *	1995-08-15	1998-02-17	American Home Products Corporation	5H,8H-2-oxa-1,3,5,8-tetraaza-cyclopenta b!-naphthalene-6,7-diones
US6017903A (en)	1996-09-27	2000-01-25	Guilford Pharmaceuticals Inc.	Pharmaceutical compositions and methods of treating a glutamate abnormality and effecting a neuronal activity in an animal using NAALADase inhibitors
US5824662A (en)	1996-09-27	1998-10-20	Guilford Pharmaceuticals Inc.	Treatment of global and focal ischemia using naaladase inhibitors
PL332413A1 (en)	1996-09-27	1999-09-13	Guilford Pharm Inc	Compositions containing inhibitors of naaladase as well as methods of treating glutamatic anomaly and influencing neuronic functions among animals
IL131004A0 (en) *	1997-01-23	2001-01-28	Smithkline Beecham Corp	Il-8 receptor antagonists
FR2760237B1 (fr) *	1997-02-28	1999-04-16	Rhone Poulenc Rorer Sa	Thiazolobenzoheterocycles, leur preparation et les medicaments les contenant
US6288075B1 (en)	1998-02-26	2001-09-11	Rhone-Poulenc Rorer S.A.	Thiazolo[5,4,3-ij]quinolines, preparation and medicines containing the same
FR2766487B1 (fr) *	1997-07-28	1999-08-27	Rhone Poulenc Rorer Sa	Thiazolobenzoheterocycles, leur preparation et les medicaments les contenant
US6262044B1 (en)	1998-03-12	2001-07-17	Novo Nordisk A/S	Modulators of protein tyrosine phosphatases (PTPASES)
WO1999046267A1 (en) *	1998-03-12	1999-09-16	Novo Nordisk A/S	Modulators of protein tyrosine phosphatases (ptpases)
JP2009286778A (ja) *	2008-04-30	2009-12-10	Sumitomo Chemical Co Ltd	ｔｅｒｔ−ブチル３−アミノピペリジン−１−カルボキシレートの製造方法およびその中間体
EP2338492A1 (en)	2009-12-24	2011-06-29	Universidad del Pais Vasco	Methods and compositions for the treatment of alzheimer
EP3427729A1 (en)	2017-07-13	2019-01-16	Paris Sciences et Lettres - Quartier Latin	Probenecid for use in treating epileptic diseases, disorders or conditions
CN113549087A (zh) *	2020-04-26	2021-10-26	北京鼎材科技有限公司	一种化合物及其应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA1246578A (en) *	1982-03-29	1988-12-13	John H. Musser	2-oxo-1,3-oxazolo[4,5]quinolines useful as anti-allergy agents
DK146787A (da) *	1987-03-23	1988-09-24	Ferrosan	Heterocykliske forbindelser, deres fremstilling og anvendelse

1988
- 1988-06-28 DK DK356788A patent/DK160941C/da not_active IP Right Cessation
1989
- 1989-06-21 IE IE200889A patent/IE64289B1/en not_active IP Right Cessation
- 1989-06-22 US US07/369,762 patent/US4977155A/en not_active Expired - Fee Related
- 1989-06-23 IL IL9073389A patent/IL90733A/en not_active IP Right Cessation
- 1989-06-23 CA CA000603702A patent/CA1326670C/en not_active Expired - Fee Related
- 1989-06-26 AT AT89111622T patent/ATE95181T1/de active
- 1989-06-26 ES ES89111622T patent/ES2059636T3/es not_active Expired - Lifetime
- 1989-06-26 DE DE89111622T patent/DE68909513T2/de not_active Expired - Fee Related
- 1989-06-26 EP EP89111622A patent/EP0348872B1/en not_active Expired - Lifetime
- 1989-06-27 AU AU37077/89A patent/AU619863B2/en not_active Ceased
- 1989-06-27 NZ NZ229730A patent/NZ229730A/en unknown
- 1989-06-27 NO NO892680A patent/NO169390C/no unknown
- 1989-06-28 ZA ZA894903A patent/ZA894903B/xx unknown
- 1989-06-28 PH PH38872A patent/PH27565A/en unknown
- 1989-06-28 JP JP1164091A patent/JPH0248578A/ja active Pending
- 1989-06-28 FI FI893170A patent/FI91259C/fi not_active IP Right Cessation
- 1989-06-28 KR KR1019890008933A patent/KR910000735A/ko not_active Ceased
- 1989-06-28 PT PT91010A patent/PT91010B/pt not_active IP Right Cessation
1990
- 1990-08-20 US US07/570,019 patent/US5075306A/en not_active Expired - Fee Related
- 1990-08-22 US US07/570,819 patent/US5109001A/en not_active Expired - Fee Related
- 1990-08-22 US US07/570,903 patent/US5057516A/en not_active Expired - Fee Related
- 1990-08-23 US US07/572,172 patent/US5079250A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
EP0348872A1 (en)	1990-01-03
ATE95181T1 (de)	1993-10-15
FI893170A0 (fi)	1989-06-28
ES2059636T3 (es)	1994-11-16
US5079250A (en)	1992-01-07
CA1326670C (en)	1994-02-01
KR910000735A (ko)	1991-01-30
ZA894903B (en)	1990-03-28
US5109001A (en)	1992-04-28
EP0348872B1 (en)	1993-09-29
FI91259C (fi)	1994-06-10
US5075306A (en)	1991-12-24
US4977155A (en)	1990-12-11
PT91010A (pt)	1989-12-29
DE68909513T2 (de)	1994-01-20
DK356788D0 (da)	1988-06-28
AU3707789A (en)	1990-01-04
NO169390B (no)	1992-03-09
NO892680L (no)	1989-12-29
IL90733A0 (en)	1990-01-18
DK160941C (da)	1991-10-21
PT91010B (pt)	1995-01-31
US5057516A (en)	1991-10-15
DK160941B (da)	1991-05-06
DK356788A (da)	1990-03-21
IE892008L (en)	1989-12-28
NO169390C (no)	1992-06-17
DE68909513D1 (de)	1993-11-04
AU619863B2 (en)	1992-02-06
PH27565A (en)	1993-08-18
IL90733A (en)	1994-02-27
JPH0248578A (ja)	1990-02-19
FI91259B (fi)	1994-02-28
IE64289B1 (en)	1995-07-26
NO892680D0 (no)	1989-06-27
NZ229730A (en)	1991-07-26

Publication	Publication Date	Title
FI893170L (fi)	1989-12-29	Menetelmä uusien terapeuttisesti käyttökelpoisten 1,2,3-triatsolo/4,5-f/kinoksaliinijohdannaisten valmistamiseksi
FI890282L (fi)	1989-07-21	Menetelmä terapeuttisesti käyttökelpoisten 23,24-didehydro-25-hydroksikalsiferolijohdannaisten valmistamiseksi
FI906438L (fi)	1991-06-30	Menetelmä uusien, terapeuttisesti käyttökelpoisten A-nor-steroidi-3-karboksyylihappojohdannaisten valmistamiseksi
FI881180L (fi)	1988-09-14	Menetelmä terapeuttisesti käytettävien tetrahydronaftaleenijohdannaisten valmistamiseksi
PT88596A (pt)	1988-10-01	Process for preparing 2-anilinopyrimidine derivatives useful aspesticidas
NO167034C (no)	1991-09-25	Fremgangsmaate for fremstilling av 1,6-diklor-1,6-dideoksy-beta-d-fruktofuranosyl-4-kloro-4-dioksy-alfa-galactopyranosid
FI981807L (fi)	1998-08-24	Menetelmä terapeuttisesti käyttökelpoisten starburst-konjugaattien valmistamiseksi
FI871492L (fi)	1987-04-06	Menetelmä lääkeaineina käyttökelpoisten 2-tiometyyli-substituoitujen 1,4-dihydropyridiinien valmistamiseksi
FI883632L (fi)	1989-02-05	Menetelmä uusien, terapeuttisesti käyttökelpoisten eetterien valmistamiseksi
FI890245A0 (fi)	1989-01-17	Menetelmä uusien terapeuttisesti käyttökelpoisten 1,4-disubstituoitujen piperidinyylijohdannaisten valmistamiseksi
FI873350A (fi)	1988-02-05	Menetelmä terapeuttisesti käyttökelpoisten 1,4-dihydropyridiinijohdannaisten valmistamiseksi
FI880467A0 (fi)	1988-02-02	Menetelmä terapeuttisesti käyttökelpoisten substituoitujen 3,4-dihydro-2H-bentsopyraanien valmistamiseksi
FI884660L (fi)	1989-04-13	Menetelmä terapeuttisesti aktiivisten 2,2-dimetyylikromeenijohdannaisten valmistamiseksi
FI893003L (fi)	1989-12-21	Menetelmä uusien terapeuttisesti käyttökelpoisten neplanosiinijohdannaisten valmistamiseksi
KR850004570A (ko)	1985-07-25	2,2-디플루오로프로피온산 유도체의 제조방법
FI925260L (fi)	1992-11-19	Menetelmä terapeuttisesti käyttökelpoisten 6-amino-substituoitujen oktahydro-1,7,8-indolitsiinitriolijohdannaisten valmistamiseksi
FI98459B (fi)	1997-03-14	Menetelmä terapeuttisesti käyttökelpoisten 5-etano-2,3,4,5-1H-2-bentsatsepin-7-olikarbamaattijohdannaisten valmistamiseksi
FI874789L (fi)	1988-05-05	Menetelmä valmistaa farmakologisesti aktiivisia substituoituja 1H-imidatsoleja
FI911701L (fi)	1991-10-11	Menetelmä terapeuttisesti käyttökelpoisten 2-substituoitujen alkyyli-3-karboksikarbapeneemien valmistamiseksi
FI893682L (fi)	1990-02-14	Menetelmä terapeuttisesti käyttökelpoisten 1,2,5-ditiatsosiinijohdannaisten valmistamiseksi
DE3885482D1 (de)	1993-12-16	Pyridyloxy-Derivate.
DK360888A (da)	1989-01-02	3',4'-dinitrogen-substituerede epipodophyllotoxinglucosidderivater
DK10190D0 (da)	1990-01-12	1,1-dioxo-cephem-4-carbothiolsyrederivater
KR860005812A (ko)	1986-08-13	4,4-디알킬-2-아제티디논의 제조 방법
FI93216C (fi)	1995-03-10	Analogiamenetelmä terapeuttisesti käyttökelpoisten 1,3-dioksaanialkeenihappojohdannaisten valmistamiseksi

Legal Events

Date	Code	Title	Description
1994-02-01	BB	Publication of examined application
1998-01-12	MM	Patent lapsed
2004-08-31	MM	Patent lapsed	Owner name: NOVO NORDISK A/S