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FI890123A0 - Menetelmä valmistaa terapeuttisesti vaikuttavia indolyylipiperidiiniyhdisteitä - Google Patents

Menetelmä valmistaa terapeuttisesti vaikuttavia indolyylipiperidiiniyhdisteitä

Info

Publication number
FI890123A0
FI890123A0 FI890123A FI890123A FI890123A0 FI 890123 A0 FI890123 A0 FI 890123A0 FI 890123 A FI890123 A FI 890123A FI 890123 A FI890123 A FI 890123A FI 890123 A0 FI890123 A0 FI 890123A0
Authority
FI
Finland
Prior art keywords
therapeutically active
method prepares
indolylpiperidine compounds
indolylpiperidine
compounds
Prior art date
Application number
FI890123A
Other languages
English (en)
Swedish (sv)
Other versions
FI91863B (fi
FI890123A (fi
FI91863C (fi
Inventor
Masaaki Matsuo
Takashi Manabe
Shinji Shigenaga
Hiroshi Matsuda
Original Assignee
Fujisawa Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB888800795A external-priority patent/GB8800795D0/en
Priority claimed from GB888818260A external-priority patent/GB8818260D0/en
Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co
Publication of FI890123A0 publication Critical patent/FI890123A0/fi
Publication of FI890123A publication Critical patent/FI890123A/fi
Publication of FI91863B publication Critical patent/FI91863B/fi
Application granted granted Critical
Publication of FI91863C publication Critical patent/FI91863C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
FI890123A 1988-01-14 1989-01-11 Menetelmä valmistaa terapeuttisesti vaikuttavia indolyylipiperidiiniyhdisteitä FI91863C (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB888800795A GB8800795D0 (en) 1988-01-14 1988-01-14 New indolylpiperidine compounds processes for preparations thereof & pharmaceutical composition comprising same
GB8800795 1988-01-14
GB888818260A GB8818260D0 (en) 1988-08-01 1988-08-01 New indolylpiperidine compounds processes for preparation thereof & pharmaceutical composition comprising same
GB8818260 1988-08-01

Publications (4)

Publication Number Publication Date
FI890123A0 true FI890123A0 (fi) 1989-01-11
FI890123A FI890123A (fi) 1989-07-15
FI91863B FI91863B (fi) 1994-05-13
FI91863C FI91863C (fi) 1994-08-25

Family

ID=26293316

Family Applications (1)

Application Number Title Priority Date Filing Date
FI890123A FI91863C (fi) 1988-01-14 1989-01-11 Menetelmä valmistaa terapeuttisesti vaikuttavia indolyylipiperidiiniyhdisteitä

Country Status (16)

Country Link
US (2) US4935432A (fi)
EP (1) EP0324431B1 (fi)
JP (1) JPH0759577B2 (fi)
KR (1) KR0130899B1 (fi)
CN (1) CN1021733C (fi)
AU (1) AU620583B2 (fi)
CA (1) CA1336605C (fi)
DE (1) DE68901039D1 (fi)
DK (1) DK733788A (fi)
ES (1) ES2032339T3 (fi)
FI (1) FI91863C (fi)
GR (1) GR3004987T3 (fi)
HU (2) HU202224B (fi)
IE (1) IE63476B1 (fi)
IL (1) IL88903A (fi)
NO (1) NO172539C (fi)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK733788A (da) * 1988-01-14 1989-07-15 Fujisawa Pharmaceutical Co Indolylpiperidinderivater og fremgangsmaade til fremstilling deraf
US5521196A (en) * 1994-10-05 1996-05-28 Eli Lilly And Company 5-HT1F agonists for the treatment of migraine
US5521197A (en) * 1994-12-01 1996-05-28 Eli Lilly And Company 3-<1-alkylenearyl>-4-<1,2,3,6-tetrahydropyridinyl>-and 3-<1-alkylenearyl>-4-piperidinyl-1h-indoles: new 5-HT1F agonists
DE19500689A1 (de) * 1995-01-12 1996-07-18 Merck Patent Gmbh Indolpiperidin-Derivate
WO1996029075A1 (en) * 1995-03-20 1996-09-26 Eli Lilly And Company 5-substituted-3-(1,2,3,6-tetrahydropyridin-4-yl)- and 3-(piperidin-4-yl)-1h-indoles: new 5-ht1f agonists
US6458806B1 (en) * 1996-08-15 2002-10-01 Millennium Pharmaceuticals, Inc. Aryl alkenamides derivatives as MCP-1 antagonists
ES2165274B1 (es) * 1999-06-04 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de indolilpiperidina como agentes antihistaminicos y antialergicos.
CN1158258C (zh) * 1999-06-24 2004-07-21 东丽株式会社 肾上腺素能α1B受体拮抗药
US6376514B1 (en) * 2000-10-17 2002-04-23 The Procter & Gamble Co. Substituted six-membered heterocyclic compounds useful for treating multidrug resistance and compositions and methods thereof
US6693099B2 (en) * 2000-10-17 2004-02-17 The Procter & Gamble Company Substituted piperazine compounds optionally containing a quinolyl moiety for treating multidrug resistance
ES2172436B1 (es) 2000-10-31 2004-01-16 Almirall Prodesfarma Sa Derivados de indolilpiperidina como agentes antihistaminicos y antialergicos.
JP4544820B2 (ja) * 2001-03-09 2010-09-15 オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド 複素環化合物
ES2201907B1 (es) 2002-05-29 2005-06-01 Almirall Prodesfarma, S.A. Nuevos derivados de indolilpiperidina como potentes agentes antihistaminicos y antialergicos.
RU2005106274A (ru) 2002-09-06 2005-11-10 Янссен Фармацевтика, Н.В. (Be) Гетероциклические соединения
CA2497829A1 (en) * 2002-09-06 2004-03-18 Janssen Pharmaceutica, N.V. Method to treat allergic rhinitis

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2193584B1 (fi) * 1972-07-28 1975-08-08 Roussel Uclaf
GB1425354A (en) * 1973-10-10 1976-02-18 Wyeth John & Brother Ltd Indole derivatives
FR2258843B1 (fi) * 1974-01-30 1977-09-09 Roussel Uclaf
IL48508A (en) * 1974-12-09 1979-10-31 Roussel Uclaf Pharmaceutical compositions comprising piperidylindole derivatives
FR2349331A1 (fr) * 1976-04-30 1977-11-25 Roussel Uclaf Nouveaux derives de 2,3 dihydro a/4-(3-indolyl) 1-piperidinyl/methyl 1,4-benzodioxin-2-methanol, un procede pour leur preparation et leur application comme medicaments
US4359468A (en) * 1981-02-25 1982-11-16 Boehringer Ingelheim Ltd. Antiallergic N-[4-(indolyl)-piperidino-alkyl]-benzimidazolones
JPS57188567A (en) * 1981-05-13 1982-11-19 Fujimoto Seiyaku Kk Novel preparation of etomidoline
US4443461A (en) * 1981-09-10 1984-04-17 John Wyeth & Brother Limited N-[2-[[1-[1H-Indolylalkyl- or oxoalkyl]-4-piperidinyl]-amino]-2-oxoethyl]-arylcarboxamide derivatives
FR2533924A1 (fr) * 1982-10-05 1984-04-06 Roussel Uclaf Nouveaux derives du 4-(1h-indol-3-yl)a-methyl piperidine-1-ethanol, leurs sels, le procede de preparation, l'application a titre de medicaments et les compositions les renfermant
JPS60142981A (ja) * 1983-12-28 1985-07-29 Yoshitomi Pharmaceut Ind Ltd ３−インド−ルカルボキサミド誘導体
US4673684A (en) * 1984-04-04 1987-06-16 Terumo Corporation Amide derivatives and 5-lipoxygenase inhibitors containing the same as an active ingredient
US4548939A (en) * 1984-10-01 1985-10-22 Janssen Pharmaceutica N. V. 1H-Indol-3-yl containing 1,3-dimethyl-1H-purine-2,6-diones
IE58370B1 (en) * 1985-04-10 1993-09-08 Lundbeck & Co As H Indole derivatives
US4742057A (en) * 1985-12-05 1988-05-03 Fujisawa Pharmaceutical Co., Ltd. Antiallergic thiazole compounds
DK733788A (da) * 1988-01-14 1989-07-15 Fujisawa Pharmaceutical Co Indolylpiperidinderivater og fremgangsmaade til fremstilling deraf
GB8819024D0 (en) * 1988-08-10 1988-09-14 Glaxo Group Ltd Chemical compounds
GB8903036D0 (en) * 1989-02-10 1989-03-30 Glaxo Group Ltd Chemical compounds

Also Published As

Publication number Publication date
IL88903A0 (en) 1989-08-15
NO890155D0 (no) 1989-01-13
CA1336605C (en) 1995-08-08
NO890155L (no) 1989-07-17
CN1021733C (zh) 1993-08-04
FI91863B (fi) 1994-05-13
JPH0759577B2 (ja) 1995-06-28
AU620583B2 (en) 1992-02-20
US4935432A (en) 1990-06-19
FI890123A (fi) 1989-07-15
HU211485A9 (en) 1995-11-28
CN1035112A (zh) 1989-08-30
GR3004987T3 (fi) 1993-04-28
EP0324431A1 (en) 1989-07-19
IE63476B1 (en) 1995-04-19
ES2032339T3 (es) 1993-02-01
NO172539B (no) 1993-04-26
HUT49871A (en) 1989-11-28
FI91863C (fi) 1994-08-25
KR890011872A (ko) 1989-08-23
IL88903A (en) 1993-03-15
NO172539C (no) 1993-08-04
US5017703A (en) 1991-05-21
JPH01221377A (ja) 1989-09-04
DK733788A (da) 1989-07-15
EP0324431B1 (en) 1992-03-25
KR0130899B1 (ko) 1998-04-23
DK733788D0 (da) 1988-12-30
IE890048L (en) 1989-07-14
DE68901039D1 (de) 1992-04-30
HU202224B (en) 1991-02-28
AU2837089A (en) 1989-07-20

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Legal Events

Date Code Title Description
BB Publication of examined application
MM Patent lapsed
MM Patent lapsed

Owner name: FUJISAWA PHARMACEUTICAL CO., LTD.